Cervus canadensis (wapiti): 122433836
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Entry
122433836 CDS
T07554
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad00230
Purine metabolism
ccad01100
Metabolic pathways
ccad04024
cAMP signaling pathway
ccad05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122433836 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
122433836 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122433836 (PDE10A)
Enzymes [BR:
ccad01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
122433836 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
122433836 (PDE10A)
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GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
122433836
NCBI-ProteinID:
XP_043312732
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Position
33:complement(34930261..35268161)
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AA seq
1067 aa
AA seq
DB search
MASPEKPLAPRPQAPLPAAGDEPGSGKLRPEPGRSAAGGRSAAGPGPAPEPPGRGPAERA
WSPLPPPSSAGRASPPGGPGALSARGGGGGWVAARAPFALAFSSPVRASAPSSFYFWPPP
PQPPPSLLPSSSAFHLPARLPGREGAAAAAAAARGGGGDAGGGRGQEAAPLSVPPSRSHR
GGGGRRRLFLSPALRGLLLSARAGPRPPPPPPRLPFGPAAPRAGSRGFPGAGGGCPAHGP
GPSPGGGGRTARRPRGPGAALAAAFPLLFGSDMEDGPSNNASCFRRLTECFLSPNLTDEK
VKAYLSLHPQVLDEFVSESVSAETIEKWLKRKNKKSEDESAPKEVSRYQDTNMQGVVYEL
NSYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGECNNSLCVFIPPGIKEGKPK
LIPAGPIAQGTTTSAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIG
DLIGILELYRHWGKEAFRLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSK
TYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNQELYSDLFDIGEEKEGKPVFKK
TKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSV
IGVVQMVNKLSGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYH
SICTAEEWQGLMHFSLPGRLCKEIELFHFDVGPFENMWPGIFVYMIHRSCGTACFELEKL
CRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQSNHGLFTDLERKGLLIACLCHDLDHR
GFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRK
AIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTRLT
ANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQIFPAT
EPLLKACRNNLSQWEKVIRGEESALGILDTPELAQESSEKLPVKTDD
NT seq
3204 nt
NT seq
+upstream
nt +downstream
nt
atggccagccccgaaaagccactcgctccccgcccccaggcccccctgcccgcggcgggg
gacgagcccggctccggcaaactccgcccggagcccgggcgcagcgccgccggcgggagg
agcgcagcgggcccgggcccggcccccgagccgcctggccgcggcccggccgagcgcgcc
tggtccccgctcccgcccccctcttccgctggccgcgccagccccccggggggccccggc
gccctgtctgcgcgcggcggcgggggcggctgggtcgcagcgcgcgctcccttcgcgctc
gccttctcctccccggtccgcgcctccgctccatcttccttttacttctggccgccgccc
ccccaacccccgccttctcttctcccctcctcatctgccttccacctccccgcgcgtctc
ccaggaagggagggcgcagcggcggcggcggcggcggcccgaggaggcggcggcgatgct
ggcggcggcagaggacaagaggcggctcccctgagcgtcccccccagcaggagtcaccgc
ggcggcggcgggcggcggcggctcttcctctcccccgcgctccggggcttgctgctctcg
gcccgtgccgggccccggccgccgccgccgccgccccggctcccgttcggcccggccgcc
ccccgcgcgggctcccgcggcttcccgggcgccggcgggggctgccccgctcacggtccc
ggtcccagcccgggcggcggcggccgaacggcgcggcggccccgaggccccggcgccgcg
ctcgccgccgcgttcccgctgctcttcggctccgacatggaagatggaccttctaataat
gcgagctgcttccgaaggctgacggagtgtttcctgagccccaatttgacagatgaaaaa
gtgaaggcctatctttctctccaccctcaggtattagatgaatttgtgtctgaaagcgtt
agtgcagagactatagaaaaatggctgaagcggaaaaacaagaaatcagaagatgaatca
gctcctaaggaagtcagcaggtatcaagatacaaatatgcaaggagttgtgtatgaacta
aacagctatatagaacaacggctggatacaggaggtgacaaccagctactcctctatgaa
ttgagtagcatcatcaaaattgccacgaaagctgatggatttgcattgtatttcctggga
gagtgcaataacagcctttgtgtgtttatcccgcctggaatcaaggaaggaaaacccaag
ctcatccccgcgggtcccatcgcccagggcaccaccacctccgcctacgtggccaagtcc
agaaaaacgttgctggtggaagacatcctcggggatgaacggtttccaagaggtacgggg
ctggaatcggggacgcggatccagtccgttctgtgcttgccgatcgtcaccgcgatcggg
gacttgatcggcatcctggagctctaccggcactggggcaaggaagccttccgcctgagc
caccaggaggttgcaacagcaaatcttgcctgggcttcagtagcaatacatcaggtgcag
gtatgcagaggtcttgccaaacagactgaactgaatgactttctactcgacgtatcaaaa
acgtattttgataacatagttgcaatagattctctacttgaacacataatgatatatgca
aaaaacctggtgaatgccgaccgttgtgcccttttccaggtagaccataagaaccaggag
ttatattcagacctttttgatattggagaggaaaaggaagggaagcccgtcttcaagaag
accaaggagatcaggttttcaatcgagaagggaatcgctggccaagtagcaagaaccggg
gaagttttgaacattccagatgcctacgcagacccgcgctttaacagagaggtggacctg
tacacgggctacacgacccggaacatcctgtgcatgccgatcgtcagccggggcagcgtc
atcggcgtggtgcagatggtcaacaagctcagcggcagcgccttctccaagacggacgag
aacaacttcaagatgtttgccgtcttctgtgctttagccttacactgtgccaatatgtac
cacaggatccggcactcggagtgcatctacagggtcaccatggagaagctgtcctaccac
agcatctgcaccgcggaggagtggcaaggcctcatgcacttcagcctgcccggccggctg
tgcaaagagatcgagctgttccactttgacgtcggcccctttgaaaacatgtggcctgga
attttcgtgtacatgatccaccgatcctgtgggacagcctgcttcgagctggagaagctg
tgtcgtttcatcatgtccgtgaagaagaactaccgccgggtcccttaccacaactggaag
cacgcggtgacggtggcgcactgcatgtacgccattctgcagagcaaccacgggctcttc
accgacctcgagcgcaaaggcctgctcatcgcatgtctgtgccatgacctggaccaccgc
ggcttcagcaatagctacctgcagaagttcgaccacccgctggccgcgctctactccacg
tccaccatggagcaacaccatttctcccagaccgtgtccatcctgcagttggaagggcac
aacatcttctccactctgagctccagcgaatacgagcaggtacttgagatcatccgcaaa
gccatcatcgccacagaccttgctctgtacttcgggaaccggaagcagctggaggagatg
taccagaccggatcgctgaaccttaataaccaatcacatagagaccgtgtcatcggtttg
atgatgaccgcctgtgatctttgttctgtgacaaagctgtggccagtgacgagactgacg
gccaacgacatatacgcagagttctgggcggagggcgatgaaatgaagaagctggggata
cagcccattcccatgatggacagagacaagaaggacgaggttccgcaaggccagctgggg
ttctacaacgccgtggccattccctgctacaccaccctcacccagatcttccccgccacg
gagccgctcctgaaggcgtgcaggaataacctgagccagtgggagaaggtgatccggggc
gaggagagcgccctggggatcctggacacgccagagctggcccaggagtcctcggagaag
ctgcccgtgaagaccgatgactga
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