Cervus canadensis (wapiti): 122434024 Help Entry 122434024         CDS       T07554                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism ccad  Cervus canadensis (wapiti) Pathway ccad04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:ccad00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     122434024 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:ccad03036]     122434024 (SYNE1) Chromosome and associated proteins [BR:ccad03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     122434024 (SYNE1) SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH KASH Spectrin_SYNE1_2 SR_desmoplakin_3 SYNE3 Motif Other DBs NCBI-GeneID:  122434024 NCBI-ProteinID:  XP_043313091 LinkDB All DBs Position 33:complement(24161150..24636075) Genome browser AA seq 8829 aa AA seqDB search MAASRAASRAPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDG VKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSVYRGSPIKLVNINSTD IADGRPSIVLGLMWTIILYFQIEELTSNLPQLQALSSSTSSVDSMVSSETASPPSKRKVA TKIQGNAKKALLKWVQYTVTKQSGIEVKDFGRSWRSGVAFHSVIHAIRPELVDLEKVKGR PNRENLEEAFSIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKQYPDIHSTGSDGQ ENDEILPSFPSFTNSIQILKREDRLILKEMKVWIEQFERDLTRTQVTDSSLQDKYQSFKH FRVQYEMKRKQIEHLLQPLHRDGKLSLDQALVKQAWDRVSSSLFDWHIQLDKSLPAPLGT IGAWLYRAEVALREEITIQQVHEETANTIHRKREQHKDLLQNTDAHKRAFHEIYRTRSVN GIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGGR DSVELLLQNYISFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQ WRNLSVEVRSVRSMLEEVIANWDRYGSTVASLQAWLEDAEKMLNQSEHAKKDFFRNLPHW IQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYARADELDRMKKEY NDCVTVLSEFATGAHRKLSEPLEVSFINVKLLIQDLEDIEQRVPVMDAQYKMITKTAHLI TKEISQEEANEMFATMSGLKEQLTKVKDCYSPLLSESQQLLVPLEELEKQMTAFYDSLGK IDEIMTVLEHEAQSSPLFKQKHQELLACQESCKKAMTQIEKGSQSVQKFVTLSNVLKHFD QTKLQRKIADMHVAFQNMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRVAQEGLEEK GDPEDLLKRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQRGLQEAVRKLHKQWKDLQA EAPYHLLHLKIEVEKNRFLASVEECRAELDRETKLVPQEGSEKVIKEHRIFFSDKGPHHL CEKRLQLIEELCLKLPVRDAVRNTPETCHVTLKELRAAIDCTYAKLVGDPDKWKDYTSRI YEFSSWISAKETQLKGIKNETIDTANQGEVKRAVEEIRSGITKKGETLSWLKSRLKILIE VSSEDEAQKQGDELAKLSSSFKALGTLLSEVEKMLSNFGDCVQYKEIVKSSLEELITGSK EVQEEAEKILDTENLFEAQQLLLHHQQKTKRINAKKKDVQQQIAQAQQGEGGLPGRVQEE LRKLESTLDGVEHSREKQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLE SLSSELEQTKEFSKRTEGIAVQAENLVKEASEIPLGPKNKQLLQQQAKSIKEQVKKLEDT LEEDIKTMEMVKNKWDHFGTNFETLSVWITEKEKELNALETSSSAMDTQINQIKVMIKEI ESKISSITGLEEEAQSFAQFITTGESARIKAKLTQIRRYWEELREYAQSLQGIILGHLSQ QKKFEENLKKIQQSVSEFEDKLADPVKICSSATETYKVLQEHMDLCQAVESLTSTVAALS ASARKVSNRDSSIQEAATVQRSYEGLLGRAKERQRELETLLACWQRLEKELSTFLTWLER CEVIASSPEADISADRVKVESELQSIQVLQNEVVAQASIYSNLLQLKESLFSVASRDDVI MMKLQLEHLDERWRDLPQIISKRINFLQSVVTEHQQFDELLLSFSVWIKLFLSELQTTSE ISVMDHQAALTRHKDHAAEVESKKGELQSLQGHLAKLGALGRAEDLHLLQGKAEDCLQLF EEASQVVERRQRALCQLAPFLQSHASLSESLHQLRQTVEATHSMNKKQSDLLERHLNDAI RNVKTLESAAISLDGLLTKAQYHLKSGSAEQRTSCRATADHLSVELERIQNLLGTKQSEA DALAVLKKAFQDQKEELLKSIEDIEERTDKERLKDLTRQALQQRLRVFNQLEDELNSHEH ELCWLKDKAKQIAQKDVAFAPEVDKEINRLEVTWDDTKKLIHENQGQCCGLIDLIREHQN LKSAITKVLENASNVIATRTTVKDQEDLKWALSKHEAAKNEMCNKQKDLDNFTSKGKQLL SELKKIHSGDFIVVKTDMESTVDKWLDISEKIEESMDRLRVSLSIWDDVLSSKNEIDGWS NHSVPQLTESISNLNDSLRAEEFLKEFESEVKKKALRLEELHSKVIDLKELTKNPETPPD LQFIEADLRQKLEHAKEITEEAKGTLKEFTAQSAQVEKFINDTASWLTKLEESLMNCAQT ETCEGLKKVKDIQKELQSQQSNISTTQENLNSLCRKYHSVELGSLGSAMTGLIKRHEAVS QSCSKTQASLQDSLEKHFNESMQEFQEWFSGIKAAAKESSDRTGDSKVLEAKLHDLQNIL DSVGDGQSKLDAVTREGQTLYAHLSKQIVSSIQEQVTKANEEFQAFLKQCLKDKQALQDC ALELGSFEDQHRKLNLWIHEMEERLSTENLGESKQHIPEKKNEVHKIEMFLGELLAARES LDKLSQRGQLLSEEGHGAGKESRLCSQLLTSYQNLLRMTKEKLRGCQVALQEHEALEEAL QSMWSWVKGMQDRLASAESTAGSKAALERRLLQVQEILLMKGEGEVKLNMAIGKGEQALR SSNKEGQKVIQTQLQTLKDVWANIMGSSVHAQSTLESVISQWNDYLEWKNQLEQWMESVD QKVEHPLQLQPGLKEKFSLLDHFQSIVSEAEDHSGALQRLTAKARELYQKTEDETFKDTA QEELKTQFNDILTVSKEKMRKVEEIVKDHLMYLDAVQEFMDWLHSAKEELHRWSDMSGDS PATQKKLSKIKELMDSREIGASRLSRVESLAPAVKQNTTASGCELLDTEMQALRADWKQW EDSVFQTQTSLENLVSQMALSEQEFSGQVAQLEQALEQFSALLTSWAQQLALLEGKNTDK ELVECWQKGREILDALQKAEPQTENLKSQLNELCQFSRDLSTYSGKVSGLIKEYNCLCLQ ASKGCQNKEQILQQRFLRAFKDFQQWLVNAKITTAKCFDIPQNINEVSTSLQKIQEFLSE SENGQHKLNMMLSKGELLCTLLTKEKASGIQAKMATAKEDWKNFHSNLHQKESALENLKI QMKDFEVSAEPVQDWLSKTEKMVHGSSNRLYDLPAKRREQQKLQSVLEEINCYEPQLHRL KEKAQQLWEGQAASRSFVHRVSQLSSQYLALSNVTKEKVSRLDRIVAEHNQFSLGIKDLQ DWMTDTVHVLDSYCHPTSDKSVLDSRVLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSP EGIPAIQQQLASVKDMWASLLSAAIRCKSQLEGALSKWTSYQDDVRQFSSWMDGVEASLN ESERQHAELREKAAALGKAKLLNEEVLSHGSLLETIEVKGAGMTEHYVTQLEFQDLQERY GAIRERTKEAVTKSEKLVRLHQEYQRDLKAFEAWLEKEQEKLDRYSVLEGDAHTHETALR DLQELQVRCAEGQALLNSALHTREEVIPSGIPQTEDRALESLRQDWQAYQQRLSETRTQF NNVVNKLRLMEQKFQQVAEWLKTMEEKVNLRTGRQSSRAAKEIQLHQMKKWHEEITAYRD EVEEVGARAQEILDESHVSSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESELS LSSYSDWYSSTHKNFKNVAAKIDKADKAMMGKKMKTLEGLLKDMEKGQSLLKSAREKGER ALKYLEDGEAETLRKEIHDHVERLKELTSTVRKERTTLEKGLHLTKEFSDKYKALTQWLA EYRDSLHGPEEPKMELYEKKAQLSRYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLK DKIDQLQSDYQDLCRAAKEHVCSLEAKVRDHEDYNSELQEVEKWLLQMSGRLVAPDLVET GSLETITQQLARHKAMMEEIAGFEDRLNDLKTKGDNLISQCADHLQAKLKQNVHAHLQGT RDSYSAICSTAQRVYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLKPGANPPLSRAEAV KQVKHFRALQEQARTYLDLLCSMCDLSNSSVKTTAKDIQQTEQMIEQRLAQAQNLTQGWE EIKHMKAELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQCKQASVNTIT EKVDELTKKQESPEHKEISHLNDQWLDLCLQSNNLCLQREEDLQRTRDYHDRMNVVEGFL EKFTTEWDNLARSDAESTAAHLEALKKLALALQERKKAVEDLKEQKQKMIEHLNLDDKEL VKEQTSHLEQRWFQLEDLVKRKIQVSITNLEELSVVRSRFQELMEWAEEQQPNIAEALKQ SPPPDMAQNLLMDHLAICSELEAKQMLLKSLTKDADRVMADLGLNERQIIQKALSDAQRH VSSLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQV KTCKSAQASLKTYQNEVTGLWAQGRELMKGVTEQEKSEVLGKLQELQSVYDSVLQKCSHR LQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNETAELHTQLAKYQHILEQSP EYENLLLSLQRTGQAILPTLNEVDHSYLNEKLHALPLQFNVIVDLAKDKFYKVQEAMLAR KEYASLIELTSQSLRDLEDQFSRMSHIPGHLSVKEALSLQDGWRALGGEVAGLAEAVDEL NQKKESFRSTGQPWQPDKMPQLVTLYHRLKRQTEQRVSFLEDTTSAYQEHERMCHQLEKQ LEAVRMEQSKVNEETLPAEEKLKVYHSLAGSLQNSGILLKRVTRHLEDLVSHLDPAAYEK AKHQLQAWQEELKLLTSAIGATVTECESRMVQSRDFQTELSRSLEWLRSVEAALSGPLCL DPNLRDIQEEIRKVQIHQEEVQSSLRIMNALSNKEKEKFTRAKELISADLQRTLAELSEL DGALQEALRTRQTTLTQIYSQCQRYYQVFQAANDWLEDAHEMLQLTGNGLDVESAEESLK SHMEFFSAEDQFHSNLEELQSLVANLDPLIKPTGKEDLAQKMASLEEKSQTIIQDSHAQL DLLQRCAAKWQDYQKAREEVIELMNEAEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVIN SFHEKIVALEGEASELEKTGNDASKAAISRSTTAVWQRWTRLRAVAQDQEKLLEDAVDEW TSFNNKVKKATEVIDQLQDKLPGSSAEKASKAELVTFLEYHDTFILELEGQQSALGMLRQ QALSMVQDGVTPSSGGEPPTVQEITAMQDRCLNMQEKVKKNGKIVKQELKEREVVETQIS SVKSWVQETKEYLGNPTIEIDAQLEELKILLTEATNHRQTVEKMAEEQKNKYLGLSTILP SELSLQLAEVALDLGTIHDQIQDKVKEVEQSKAMSQEFSQQIQKIARDLTTILTKLRAKT DNLVQAKTDQKVLGEELDDCHLKLMELDNAVQKFSEQNGQLGKPLAKKVGKLTELHQQTI RQAENQLSKLNQAASHLEEYNEMLELILRWIEKTKILVRGKIAWNSASQLREQYISHQTM LEESEDIHSDLEAMTEKLQCLDSVYHTETMSQQVADLGRETEELRQVIKIRLQSLHDAAK DMKKFEAELRNLQVALEQAQTTLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVHAVQVC QSALRIPEDVVTSLPLCHAALHLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMQHLQE LIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHA TMLLTVTEVEGLAEGTEDLDGELLPATSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSE ISSPPACRSPSPVAHTDASVNQDIAYYQALSPERLQTDAAKVPPSTLPPQELYEPGLEPS ATAKLDDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIEMKLSESPEQ GRSPESQMAEHQALMDEILMLQEEISELQSALADELGSGSPGSEPAERLALQSTLTVLAE RMATIRMKASGKRQLLEEKLNDQLEEQRQEQALHRYRCEADQLDHWLLNTKATLDVALGS PKEPMDMEAQLVDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAVKLRTL KGSLLELQRALQDRQLHIQQGTAQEKEESDADLAATQSPGVQEWLAQARSAWTHQRQSSL QQQKELEQELAEQKSLLQSVASLGEEILTQHSAAETSGGVGEKPDVLSQELGMEGEKSPA EDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDGQAQDKSAV TSLLDGLNQVFEEVSSQGGGTKKQNIDLEQKLYDGVSATSTWLDDVEERLFVATALLPEE TETCIFNQETLAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSV VNQRCHQMKERLQQILNFQNDLKVLVTSLADHKYIILQKLAKMFEQPVAEQIEAIQQAED GLKELDAGIIELKRRADKLQIEQPSMQELSKLQDMYEELMMTIGSRRSGLNQNLALKSQY ERALQDLADLLETGQEKTTGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKI ISFAVPQETQFHTDLMAQASAVLKGAHKRGVELEYILETWSQLDKEHWELSRQLEMVESS TPSVGLVEESEDRLIDRITLYQHLKSSLNEYQPKLYQVIDDGKRLLISVSCSDLESQLNQ LGEHWLNDTNKVSKELHRLETILKHWTRYQSESADLIHWLQTAKDRLEFWTQQSVTVPQE LEMVRDHLNAFLEFSKEVDAKSTLKSSVLSTGNQLLRLKKVDTAALRSELSHIDGQWNDL LTNIPAIQEKLHQLQMDKLPSRHAISEVMTWISLMESVIQKDEENIKNSIGYKTIHEYLQ KYKGFQIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVT EKIQLLEGLLESWSEYENNVQCLKTWFETQEKRMKQQHRIGDQASVQNAMKDCQDLEDLI KAKEKEVEKIEQNGLALVQNKKEEVSGIVRSTLQELNQTWANLDHMVGQLKILLKSVLDQ WSHHKVAFDEINSCLMEARYSLSRFCLLTGSLEAVQVQVDNLQNLQDDLEKQEKSLQKFG SVTNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLRASKALLQLWQRYKDYSKQC AAAVQQQEGRTSEFLKAATDRDIGDDEVATWIQDCNDLLKGLGPIQDSLIVLHELGGQLK QQVDASAASAIQSDWLSLSQQLHALEQALCKQQAVLQAGVLDYETFTKSLEALETWIVEA EEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMVPDLDRLNELGYRLPLNDKEIKRMQ NLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLL EQQRAHELFQAEMFSRQQILHSIIFDGQHLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRA QQRRGIIDSQIRQWQRYREMAEKLRKWLAEVSCLPVSGLGSVRIPLQQARALFDQVQFKE KVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTEIQEKWRSASVCLEEQKKTLAGL LQDWEKCENGIADSLEKLRTFKKRLSQPLPDHHEELHAEQMCCKELENAVGSWTDDLAQL TVLKQALCAYISEDDISILNERMELLQRQWEELCHQLSLRRQQVSERLNEWAVFSEKNKE LCEWLTQMESKVSQNGDILIEEMIEKLRKDYQEEIAIAQENKIQLQQMGERLARASHESK ASEIEYKLGKINDRWQHLLDLMAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKP IVYDSCDSEEIQKKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQ ATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDFSHFEDWLKISERTAAFPSSSGVL YTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDAAGSLKQMVHKGNQRWDN LQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKA FQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLI RLPLPDDEHDLSDRELELDEAGTLSDLHWRDTSTDGVLSPQPSSNPSLSLAQPLRSERSG RDTPASVDSIPLEWDHDYDLSRDLESAVSRTLPSEDEEGPEDKDFYLRGAVGISDVMIPE SPEAYVKLTESAIRNSSGDRGALESQIRQLGKALDDSHFQMQQTENIIHPKTPTGPELDS GYRGYMKLLGECSGSIDSVKRLEHKLTEEDDHFPGFVNLDSTETQTAGVIDRWELIQAEA LSKELRMKQKPQRRQQLDSDLSSVLTWLRETEGDLEQLQRLQLSTDIQSIALQIQKLKEL QKAVDHRKAIVLSIHLCSSEFTQTGQEESQDLQDRLSQMNGRWDRVCSLLEEWRGLLQDA LMQCQDFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLKQIRHELLESQLK VASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDMSSSQQD LSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSVSQPGPSVSSPHSRSIKGGSDSSL SEPRPARSGRAFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPML RYTNGPPPL NT seq 26490 nt NT seq  +upstreamnt  +downstreamnt atggccgcttccagggcagcctcgcgggcccctcgggacatcgccaacgtgatgcagagg ctgcaagatgagcaagagatagtacaaaaacgtactttcacaaaatggatcaactcacat ctggccaagcggaaacccccaatggtggtggatgatctttttgaagacatgaaagatggt gtgaagctacttgctctgctggaagtcctgtctgggcagaaactgccgtgtgaacaagga cgccggatgaagcgaattcatgccgtggcgaacattggcacagcactgaagttccttgaa gggaggaagtccgtgtacagaggatcaccgattaaattagtcaacattaactccactgat atagctgatggtcgaccctccattgttctgggattgatgtggaccattatcctgtatttc cagatcgaggagctgaccagcaacctgccacagctgcaggctctgtccagcagcacgtcc tccgtggacagcatggtcagctctgagaccgccagccccccgagcaaacggaaggtggcc accaagatccaaggaaacgctaagaaggcgctactgaagtgggtccagtacacagtcacc aagcagagtggaatagaagtaaaagacttcggccggagttggagaagtggcgtggccttt cattctgtcatccacgctattcggccggaactggtggacttggagaaggtgaaaggaagg cctaaccgagaaaacctggaggaggctttctccattgctgaaacggaactggggatccca cggctcctggaccctgaagatgttgatgtggataaaccagatgagaagtctattatgacc tatgtagcccagtttctgaagcagtatcctgacatccacagtacaggctctgatgggcaa gagaatgatgaaatacttccaagtttcccatcttttacaaattctatccaaattcttaag agagaagacaggctaattttgaaggagatgaaagtttggatagaacaatttgaaagagat ttgacaaggacacaggtgacagactcaagtttgcaggataaatatcagtcatttaagcac ttcagagttcaatatgaaatgaagaggaaacagattgaacacttattacaaccattacat agagatggtaaattgtcacttgaccaagcattggtcaaacaggcctgggatagagtgtcc tccagcctctttgattggcatatacaacttgataagtctcttcctgcacctctgggcacc ataggggcctggttatatagagcagaagtggccctaagagaggaaataaccattcagcag gttcacgaggaaactgctaacacaatacaccggaaacgtgagcaacacaaggatctgctt caaaacacagatgcccacaaaagagcattccatgaaatctaccgaaccaggtctgtgaac gggatcccagtgccacctgatcaattagaggacatggccgagaggtttcattttgtttcc tccacatcagagctacacttaatgaaaatggaatttctagaattaaagtaccgtctgctc tcactgctggttcttgcagagtcaaagctgaagtcttggatcatcaagtacggggggaga gattcagtggagctccttctacaaaactacatctcttttatagaaaatagcaagttcttt gaacaatatgaagtgacataccagatcttgaaacagacagctgagatgtatgtcaaagct gatggttcagtggaagaagctgagaatgtgatgaaattcatgaatgaaaccactgcgcag tggaggaacctctcggtggaagtcaggagcgtgcggagcatgctggaggaagtcatcgcc aactgggaccgatacggcagtactgtggctagtcttcaggcttggctcgaggacgccgag aaaatgctcaatcagtcagaacatgccaaaaaggattttttccgaaacttgcctcattgg atacagcagcacactgccatgaatgatgctggcaattttttaatcgaaacgtgtgatgag atggtttcccgtgacctcaaacagcagttactgttgctaaatgggcgatggagggagttg tttatggaagttaagcaatatgctcgagctgatgagttggacagaatgaagaaggaatac aacgattgtgttactgtcttgtctgagtttgcaactggagcccataggaaactttcagag cccttggaagtctcttttattaatgtcaagttattaattcaagacttggaggatattgag cagagggtgcctgtgatggatgctcagtataagatgattacaaagacagcgcacctcatt accaaagagatctcccaagaagaagctaatgaaatgtttgcaaccatgtctgggctcaaa gagcagctaaccaaggtcaaagactgttactccccactcctttctgagtctcagcagctg ttggtaccgttggaggaattagaaaagcagatgacggccttttatgactcacttgggaaa attgatgaaattatgacagttcttgaacatgaggcacaatctagtcctctttttaaacag aaacatcaggaactattagcttgtcaagaaagctgtaagaaagccatgactcaaattgag aaaggcagtcagagtgttcaaaagtttgtgaccttgagcaacgtgttaaagcattttgat cagacgaagctacagaggaagattgcagatatgcatgttgcttttcagaatatggtaaag aaaactggagattggaagaaacatgtggaaaccaacagccgcttgatgaagaagtttgag gagtctcgagccgagttggagaaggtgctgagggtcgctcaggagggcctggaggaaaag ggggacccggaagacctgctgaagagacacacagagtttttcagccagctggaccagagg gtgctcaatgctttcctgaaagcctgtgatgagctcactgacattctccccgagcaggag cagcggggcctgcaggaagccgtcagaaagctccacaaacagtggaaggatcttcaagca gaagctccatatcatttgcttcatctgaagattgaggtggagaagaacaggttcttagct tctgtggaagagtgcagagctgagctggaccgagagaccaagctggtgccccaggaaggc agcgaaaaggtcatcaaagagcataggatcttcttcagtgacaagggccctcaccatctc tgtgagaaaaggttacagctcattgaagaactgtgtctgaaacttccagtccgggacgca gtccggaacacaccggagacctgtcacgtgaccctcaaggagctcagagctgctattgac tgcacctacgcgaagctggtgggagacccagacaagtggaaggactacacgagcagaatt tatgagttctcctcttggatatctgcaaaggagacccagttaaaggggatcaagaatgag accattgatactgctaatcaaggagaagttaaacgtgctgtggaggagataagaagtggt attaccaaaaaaggggagactctcagctggctgaaatccaggcttaaaattctgattgaa gtttcttctgaggatgaagcccaaaagcaaggagatgagctggcaaaattatctagttct ttcaaggctctcgggactttgttgtcagaggttgaaaagatgttaagcaactttggagac tgtgtccagtacaaagaaatagtcaaaagttccctggaagagttaatcactggctctaaa gaagtccaggaagaagctgagaagatcttggacactgaaaatttgtttgaagcacaacaa ctactccttcatcaccagcaaaagacaaagaggatcaatgcaaagaagaaggacgtgcag cagcagatcgcgcaggctcagcagggagaaggtgggctgcctgggcgagtccaagaagag ctgcggaagctggagagcaccctggacggtgtggagcacagtcgggagaaacaggagcgc cgcatccaggtcacattaagaaaatgggagagatttgaaacaaacaaagagacagtggtc agatacctttttcaaacaggttccagccatgagcgcttcttgagttttagcagtttggaa agcttatcttcagaattggaacagacaaaggagttttctaaacgaacagaaggtattgca gtccaggctgagaatcttgtaaaggaagcttcagagatcccacttgggcccaagaataag cagctgcttcagcagcaggccaagtcaatcaaggagcaagttaaaaaattagaagacacc cttgaagaagatattaaaaccatggaaatggtgaaaaacaagtgggatcattttggcact aactttgagaccctgtccgtctggataactgagaaagaaaaagaactcaatgccttggag acgtcatcatctgccatggacacacaaatcaaccaaattaaggtcatgattaaggaaata gaaagtaagatcagcagcattacaggactagaagaagaagctcagtcttttgctcagttt 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cagcatttgctgtctgagatggagtcactcaagccaaaagtccacgcggtgcaggtctgt cagagcgcgctccggatccccgaggacgtggtcaccagcctgccgctctgccacgcggcc ctgcacctgcaggaggaggccagccggctccagcacacggccatccagcagtgcaacatc atgcaggaggctgtggtgcagtatgaacaatatgagcaagaaatgcagcacctccaggaa ctcatagaaggagctcacagagagattgaggataagcctgtggccaccagcaacatccag gaactgcaagcccagatttctcggcatgaggagctggctcagaaaatcaagggctaccag gagcagatcgcctctttgaactccaagtgcaagatgctgaccatgaaagccaagcacgcc accatgctgctgacggtgaccgaggtggaggggctggcggagggcacggaggacttggac ggggagctcctccccgccacctcggcccacccctctgtggtcatgatgactgcaggtcgc tgtcacactttgctgtcacctgtcactgaggaatctggggaggagggaaccaacagtgag atctcctctccgccggcttgtcgttccccttcacctgtggctcatacagacgcctctgtt aaccaggacatcgcttattaccaagccttgtctcctgagaggttacagaccgatgctgcc aaggtcccccccagcacgttgccaccccaagagctgtatgaaccgggactggagccgtct gccactgcaaagctggacgatttgcagcgctcttgggaaaccttaaagaatgtgatcagc gagaagcagcgcacactctatgaagccttggaacgccagcagaagtaccaggactccctc cagtccatctccacgaaaatggaggccatcgagatgaaactcagtgagagtccagagcag ggcaggagtcccgagagccagatggccgaacatcaggctctgatggacgagattctcatg ctccaagaggagatcagcgagctgcagtcggccctcgcggacgagctggggtccgggtcc ccagggtccgagccggcagagcggctggcgctgcagtccacgctcaccgtcttagcggag cgaatggccaccatcaggatgaaggcatctgggaagcggcagcttctggaggagaaactc aatgatcagctggaggaacagagacaggagcaagccctgcacaggtatcgctgtgaagct gatcagctggaccactggctcttgaacacgaaggccactctggatgttgccctggggtca cccaaggagcccatggacatggaggcccagttagtggactgccagaatatgctggtggaa attgagcagaaggtggtggccttatcagagctctcggtgcacaatgaaaacctgctgctg gagggcaaggctcacaccaaggacgaggccgagcagctggcagtgaagctgagaaccctc aaggggagcctcctggagctgcagagggcgctgcaggacaggcagctccacatccagcag gggacagcccaggagaaggaggagagcgatgctgacctggctgccactcagagccccggg gttcaggaatggctagctcaagctcggagcgcgtggacccaccagcgacagagcagcctc cagcaacaaaaagagttggagcaggaattggcagagcagaagagcctcctccagtcagta gccagccttggagaggaaattctaacgcagcactcagctgcagagacctctggtggtgtt ggcgaaaaacctgatgtgttatcccaggagttggggatggaaggggagaaatcacctgct gaagaccagatgagaatgaaatgggaaagcctacatcaggaatttagcaccaagcagaaa ctacttcagaatgttctggagcaggaacaggagcaagtgctctacagcaggcctaatcgg ctcctgtctggcgtgccactgtacaaaggggacgggcaggcccaggataagtctgcggtg acgtccttgctggatggattgaaccaggtcttcgaggaggtttcatcccagggtggaggg acgaagaagcaaaacattgacttggaacagaagttgtatgatggggtctcggccacctct acctggctggatgatgtagaagaacggttatttgttgccacagcccttttaccagaagag acggaaacttgcatcttcaaccaagagactcttgccaaagatattaaggaaatgtctgaa gaaatggataagaacaagaacttgttttcccaagcctttccggagaacggcgataaccga gatgttattgaagacactttgggttgtctcttgggcaggttgtctttgctagactcagta gtaaatcagcgatgtcatcagatgaaggaaagacttcagcagatattaaatttccagaat gatctgaaggtgctagttacatcactggctgaccacaaatacatcattctgcagaagctg gcgaaaatgtttgaacaacctgtggcagagcagatagaggcaatacagcaggctgaagat gggctaaaggaattagatgcgggaatcattgagttaaaaaggcgtgctgacaagttgcag attgagcagccttccatgcaagaactctccaaactccaggacatgtatgaggaactcatg atgaccattggctcccggcggagcgggctgaatcagaatcttgccctcaagagtcagtac gaaagagccttgcaggatctggctgacctactggaaaccggacaagagaagacgacagga gaccagaaaatcatcgtatcttccaaagaggaaatccaacaactacttgacaaacataag gagtactttcagggtctggagtctcacatgatcttgaccgaaaccctcttcaggaagatc atcagctttgcagtcccacaggaaactcagttccacacagacctgatggcacaggcttcg gccgtgctcaaaggggcccacaagaggggtgtggagctggagtacatcctcgagacatgg tcccaactggataaggagcactgggagcttagccggcagctggagatggtggagagcagc accccgagcgtgggtttggtggaggagagcgaagacaggcttatcgaccggatcacactc taccagcatttgaaatccagccttaatgaataccagcccaaattatatcaggtaatagat gatggaaaacgacttctgatatctgttagctgctcagatctggaaagccagctaaatcaa cttggagaacactggttaaatgataccaacaaagtgtctaaggaacttcacagattggaa acaatattgaaacactggaccagatatcaaagcgaatctgcagatctaatccactggtta cagactgcaaaagacaggctagaattttggactcaacaatctgtaacagtcccacaggaa ctggaaatggtccgtgatcacctaaatgcttttctggagttttccaaagaggtggatgcc aagtccacgctaaaatcatctgttctgagcactggaaatcagcttcttcgattaaagaaa gtagacacagctgccttgcgttctgagctgtcccacattgatggtcagtggaatgacctg ctgacaaatattccagccatacaggaaaagcttcaccagctccaaatggataaactgcct tctcgccacgccatttctgaagtcatgacttggatttctcttatggaaagtgttattcaa aaggatgaagagaatattaaaaattccatcggttacaagacaattcatgagtaccttcag aaatacaagggttttcagatcgacattaactgtaagcagctgactgttgattttgtgaac cagtctgtgctacagatcagcagtcaagatgtggaaagtaaacgcagcgacaagactgat tttgctgagcaacttggagcaatgaataaaagctggcaaatccttcagggtctggtcact gagaagattcagttgttggaaggcttattggaatcttggtcagaatatgaaaataacgta caatgtctgaaaacgtggtttgaaacccaggaaaagagaatgaaacaacaacatcgcatt ggagaccaggcttctgttcagaacgcgatgaaagactgtcaggatctggaagacttgatt aaagcaaaagagaaagaggtagagaaaattgagcagaatggacttgctttggttcagaac aagaaagaagaagtctctggcattgtcaggagcacgcttcaggagctcaaccaaacttgg gcaaatttagaccacatggttggccaactcaagatcctgttgaaatctgtgcttgatcag tggagccaccataaagtggcatttgatgagataaacagttgcctcatggaggcccgatac tctctttctcgattctgtctgcttactggctctttagaagctgtgcaagttcaagtggac aatcttcagaatcttcaagatgatctagaaaaacaggaaaagagcttgcagaaatttggc tctgtgaccaatcaacttttaaaagaatgtcacccacctgtgacagaaactcttactaat acactaaaagaagtcaacatgagatggaataacttgctggaagagattgccgagcagctg cgtgccagcaaggccctacttcagctttggcagcgatacaaggactactccaaacagtgt gccgctgcagttcaacagcaggagggacggaccagcgagttcttgaaggcagccaccgac agggacatcggtgatgacgaagttgccacctggatccaagattgcaatgacctcctcaaa ggactggggccgattcaggattctcttatagttcttcatgagctgggagggcaactcaag caacaagtggatgcttcggcagcatcagccattcaatccgattggctctctttgagtcaa caattgcatgccctagaacaggctctctgcaaacagcaggctgtgttacaggctggcgtt cttgactatgaaacctttaccaagagtttagaagctttggagacctggatagtagaagct gaagaaatactacaagggcaggaccctagccactcatctgacctctcgaccatccaggaa aggatggaggagctgaagggacagatgctgaaattcagcagcatggtcccagatttagac cgtctgaatgagcttggatacaggctgcccctgaacgataaagaaatcaaaaggatgcag aatctgaatcgtcactggtctctgatctcctcccagactacagaaagattcagtaagtta cagtcatttttgctacaacatcagactttcttggaaaaatgtgaaacatggatggaattc ctagttcaaacggaacagaagttagcagtagagatttcaggcaattatcagcatcttctg gagcagcagagagctcatgagttgtttcaagcagagatgttcagccgtcagcagattttg cactcgatcatttttgatggacagcatcttctagaacaaggtcaagttgatgacagggat gagttcaacctgaaattgacccttctcagtaatcagtggcagggggtgatccgccgggcc cagcagaggcgaggcatcatcgacagccagatccgccagtggcagcgctacagggagatg gcagaaaagctccgtaaatggctggcggaggtgtcctgtctgcccgtgagtggtctgggg agtgtccggatacccctgcagcaagcaagagccctctttgatcaagtgcagttcaaagaa aaagtgttcctgcggcaacaaggcagctacatcctcaccgtggaggccggcaagcagctt ctgctttcagccgacagcggggccgaggccgccctgcaggccgaactcactgagatccaa gagaagtggaggtcagcaagtgtgtgtctggaggagcagaagaaaacactggccggcttg ctgcaggactgggaaaaatgtgagaatggaatagctgattctctggagaaactacgaact ttcaaaaagaggctttcccagcctctcccagatcatcatgaagagctccacgcggagcag atgtgctgcaaggaattagaaaacgcagttgggagctggacagatgacttggcacagctg acagtgctgaagcaggctctctgtgcttacatcagtgaagatgatatctccatccttaac gaacgcatggagcttctgcagaggcagtgggaagaactatgccaccagctctccttaagg cgacagcaagtaagtgagagattgaatgagtgggccgtcttcagtgaaaagaacaaggag ctttgcgaatggctgactcagatggaaagcaaggtttctcagaatggagacattctcatt gaagaaatgattgagaagctcaggaaggattatcaagaggaaattgccattgcccaagaa aacaaaatacagctccagcaaatgggagaacgactggctcgagccagtcatgaaagcaaa gcatctgagattgagtacaagcttggcaagatcaatgaccggtggcagcaccttctggac ctcatggcagccagggtgaagaagctgaaggagactctggttgccgtacagcagctggat aagaacatgagcagtctgaggacgtggctagcccacatcgagtcagagctggccaaaccc atcgtctacgattcctgtgactcagaagaaatacagaaaaagcttaatgagcagcaggag ctccagagagacatcgagaagcacagcactggcgtggcctccgtgctgaacctgtgtgag gtcctgctgcatgactgtgacgcctgcgctacagacgccgagtgcgactccatccagcag gctacgcgaaacctggaccgccggtggagaaacatctgtgccatgtccatggagaggagg ctcaaaattgaagagacatggcgattgtggcagaagtttctggatgacttttctcatttc gaagattggctcaagatctcagaaaggacagctgcctttcccagctcttccggggtgctc tatacagttgccaaggaggaactaaagaaatttgaggctttccagcgacaggtccatgag agcctgacccagctggagctgatcaacaagcagtaccgccgcctggccagagagaaccgc acggacgcggccggcagcctcaaacagatggttcataaaggcaaccagagatgggacaac ctgcagaagcgcgtcacctccatcctgcgcagactcaagcatttcattggccagcgggag gagtttgagacggcccgggacagcattctggtgtggctgacggagatggatctgcagctc accaacattgagcacttctccgagtgtgacgtgcaagctaaaataaagcagctcaaggcc ttccagcaggaaatctcactgaaccacaataagattgagcagataatcgcccaaggagaa cagctgatagaaaagagtgagcccctggatgcggccgtcattgaggaagagctggatgag ctccgacgttactgtcaggaggtcttcgggcgcgtggaaagatatcataagaaactgatt cgcctgcctctcccagatgatgagcacgacctctctgaccgggagctggaactggatgag gctggaactctgtcggacctccactggcgggacacctccacggacggcgtgctctccccg cagccttcctccaacccctccctctcactcgcccagcccctccggagcgagaggtctgga cgagacaccccggccagtgtggactccatccccctggaatgggaccatgactatgacctc agccgtgacctggagtctgccgtgtccagaactctgccctctgaggatgaagagggtcca gaagataaagatttctaccttaggggagctgttggcatatcagatgtaatgatccctgaa agtcccgaggcctatgttaaactcacagaaagtgcaatcagaaattcctctggggaccgt ggtgccttggagtcgcagatccgacagctgggcaaagccttggatgacagccactttcag atgcagcaaacggagaatatcatccaccccaaaacgcccacaggaccagagctagactcc ggctacagaggctacatgaagctgctgggcgaatgcagtggcagcatagactcagtgaaa agactggaacacaagctgacggaggaagacgaccatttccctggctttgttaacttggat agcactgaaacccaaacagctggtgtgattgaccgctgggaactcatccaggcagaggcc ctgagcaaggagctgaggatgaaacagaagccccagaggaggcagcagttggactcagac ctgagcagcgttctgacctggctgcgggagacggagggcgacctggagcagcttcagcgc ctacagctcagcacggacatccagtccatcgcgctccaaatccagaagctgaaggagctc cagaaagctgtggaccaccgcaaagccatcgtcctctccatccatctgtgcagctccgag ttcactcagaccggccaggaggagagccaggatcttcaggatcgcttgtcccagatgaat gggcggtgggaccgtgtgtgctccctgctggaggagtggcggggtcttctccaggacgcg ctcatgcagtgccaggattttcatgaaatgagtcatggtttgcttcttatgctggagaac attgacagaaggaaaaatgaaattgttcccattgattctaaccttgatgcagaaatactt caggaccatcacaaacagcttaagcaaataaggcatgagctgttggaatctcaactcaaa gtggcctcgctgcaagacatgtcttgccagctgttggtgaatgctgaaggcacagactgt ttagaagccaaagaaaaagtccacgtgattggaaatcgactcaaacttctcttgaaggag gtcagtcgtcatatcaaggagctggagaagttactagacatgtcaagcagtcagcaggac ctgtcttcctggtcttctgctgacgaactggacacctcgggatctgtgagtcctacctcg ggaagaagtaccccaaacagacagaaaacgccacgaggcaaatgtagtgtctcacagcct ggaccctctgtcagcagcccacatagcaggtccataaaaggtggctccgattcctccctt tctgagcctcggccagcccggtccggccgagccttcctgttcagagtcctccgagcggct cttccccttcagctcctgctgctgcttctcattgggctggcctgcctagtcccaatgtca gaggaagactacagttgtgctctctccaacaattttgcccgatcattccaccccatgctc agatacacaaacggccctcctcctctctga

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