Cervus canadensis (wapiti): 122439524
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Entry
122439524 CDS
T07554
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad04140
Autophagy - animal
ccad04141
Protein processing in endoplasmic reticulum
ccad04210
Apoptosis
ccad04932
Non-alcoholic fatty liver disease
ccad05010
Alzheimer disease
ccad05012
Parkinson disease
ccad05014
Amyotrophic lateral sclerosis
ccad05016
Huntington disease
ccad05017
Spinocerebellar ataxia
ccad05022
Pathways of neurodegeneration - multiple diseases
ccad05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
122439524 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
122439524 (ERN1)
09143 Cell growth and death
04210 Apoptosis
122439524 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
122439524 (ERN1)
05012 Parkinson disease
122439524 (ERN1)
05014 Amyotrophic lateral sclerosis
122439524 (ERN1)
05016 Huntington disease
122439524 (ERN1)
05017 Spinocerebellar ataxia
122439524 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
122439524 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122439524 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
122439524 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccad01001
]
122439524 (ERN1)
Enzymes [BR:
ccad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
122439524 (ERN1)
Protein kinases [BR:
ccad01001
]
Serine/threonine kinases: Other
IRE family
122439524 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PQQ_3
Band_3_cyto
Motif
Other DBs
NCBI-GeneID:
122439524
NCBI-ProteinID:
XP_043320573
LinkDB
All DBs
Position
1:14308714..14390747
Genome browser
AA seq
974 aa
AA seq
DB search
MLVRLLLLLLALLLPGPGVLGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDP
VLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGK
KQDIWYVIDLLTGEKQQTLSSAFADSLCPSASLLYLGRTEYTITMYDTKTRELRWNATYF
DYAAALPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYIWQREGLRKV
MHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMV
HEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWL
LIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVSP
DMEEKFDHAPAKPEAPVDSMLKDMATIILSTFLLIGWVAFIITYPLSIHQQRQLQHQQFQ
KELEKIQLLQQQQLPFHPPGDAAQDAELQDSSGQYSESSATSSPNTSPRASNHSVHSTGS
TSKAVTSPFLEQDDEDEETSMVMVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKEALDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGSSVRDLLR
AMRNKKHHYRELPEEVQETLGALPDGFVRYFTSRFPHLLLHTYRAMELCRHERPFQPYYH
EPPEPQPPVTADAL
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atgcttgtccgattgctgctgctgctgttggcattgctgctgcccggccccggggttttg
gggagtcccagcactgtgacacttcctgaaaccttgctgtttgtgtcaacgttagatgga
agtctgcatgccgtcagcaagaggacaggctctatcaaatggactttaaaagaagatcca
gtcctgcaggttccaacacacgtggaagagcctgccttcctcccagatcccaatgatggc
agcctgtacacgcttgggggcaagaacaacgaaggcctgacgaaacttccctttacgatc
cctgagttggtgcaggcttctccgtgccgaagctcagatggcattctctacatgggtaaa
aagcaggacatttggtacgttatcgacctcctgaccggggagaagcagcagaccctgtca
tcagcctttgcagacagcctctgcccatcagcctctctgctgtatctggggcgaacagag
tacaccattaccatgtacgacaccaagacccgcgagctgcgctggaacgccacctacttc
gactacgcggccgcgctgcccgaggacgacggggactacaagatgtcccactttgtgtcc
aatggcgatgggctggtggtgacggtggacagcgagtctggggacgtcctgtggatccaa
aactatgcttcgcccgtggtggccttttacatctggcagcgcgagggtctgcggaaggtg
atgcacatcaacgttgccgtggagaccctgcgctacctgaccttcatgtcgggggaggtg
gggcgcatcaccaagtggaagtacccattccccaaggagacggaggccaagagcaagctg
acgcccaccctgtatgtggggaaatactccaccagcctctacgcttccccctcgatggta
catgagggcgtcgccgttgtgccccggggcagcacccttcctttgctggaaggcccccag
accgacggtgtcaccatcggggacaaaggggagtgtgtgatcacgcccagcacggacctg
aagttcgaccccgggctcaaaggcaagagcaagctcaactacctgcggaactactggcta
ctcatcggacaccacgaaaccccactgtccgcgtccaccaaaatgctggagcgcttcccc
aacaacctgcccaaacaccgggagaacgtgattcccgccgactcggagaagaagagcttt
gaggaggtcatcaacctggttgaccagacttcagaaaacgcacctaccacggtttctcca
gacatggaagagaagtttgatcacgcccctgccaagcccgaggcccccgtggactccatg
ctcaaggacatggccaccatcatcttaagcaccttcctgctcatcggctgggtggccttc
atcatcacctaccccctgagcatccaccagcagcggcagctccagcaccagcagttccag
aaggaactggagaagatccagctcctgcagcagcagcagctgcccttccacccacccggg
gacgcggcacaggacgccgagctccaggactcatccggccagtactcggagagctcggcc
accagcagccccaacacgtccccccgagcctccaaccactcggtccactccactggctcc
acctccaaggctgtcaccagccccttcctggagcaggacgatgaggatgaggagaccagc
atggtgatggttgggaaaatctccttctgtccaaaggacgtcctgggccacggagctgag
ggcacgattgtgtaccggggcatgtttgacaaccgcgacgtggcggtcaagaggatcctc
cccgagtgtttcagttttgcggaccgtgaggtccagctgctgagagagtcggacgagcac
ccgaacgtgatccgctacttctgcaccgagagggaccggcagttccagtacatcgccatc
gagctgtgcgcggccacgctgcaggagtacgtggagcagaaggacttcgcccacctcggc
ctggagcccatcaccctgctgcagcagaccacctcgggcctggcccacctgcactccctc
aacattgttcacagagacctgaagccccacaatatcctcctctccatgcccaacgcacac
ggcaggatcaaggccatgatctccgacttcggcctctgcaagaagctggccgtgggcagg
cacagcttcagccgccgctcgggcgtgccgggcaccgaaggctggatcgccccggagatg
ctgagcgaagactgcaaggagaaccccacctacacggtggacatcttctccgcgggctgc
gtcttctactatgtgatatccgagggtagccaccccttcggcaagtccctgcaacgccag
gccaacattctgctgggtgcctacagccttgactgcctgcaccctgagaagcatgaggac
gtcattgcccgggagttaatagagaagatgatcgccatggatccccagaagcgcccgtca
gcgaagcatgtgctgaaacaccctttcttctggagcctggaaaagcagctccagttcttc
caggacgtgagtgaccggatagagaaggaggccctggacggcccgatagtgaagcagctg
gagcgcggcgggcgggccgtggtgaagatggactggcgggaaaacatcaccgtccccctg
cagacagatctgcggaaattcagaacctataaaggcagttcggtccgagatctcctccgg
gccatgaggaataagaagcaccactaccgggagctgcccgaggaggtgcaggagacgctg
ggcgccctccccgacggcttcgtgcgctacttcacctcccgcttcccccacctcctcctg
cacacctaccgcgccatggagctgtgccgccacgagaggcccttccagccctactaccac
gagccccccgagccccagccccccgtgactgcagacgccctctga
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