Cervus canadensis (wapiti): 122440425
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Entry
122440425 CDS
T07554
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad04217
Necroptosis
ccad04380
Osteoclast differentiation
ccad04620
Toll-like receptor signaling pathway
ccad04621
NOD-like receptor signaling pathway
ccad04630
JAK-STAT signaling pathway
ccad04658
Th1 and Th2 cell differentiation
ccad04659
Th17 cell differentiation
ccad05145
Toxoplasmosis
ccad05160
Hepatitis C
ccad05161
Hepatitis B
ccad05162
Measles
ccad05164
Influenza A
ccad05165
Human papillomavirus infection
ccad05167
Kaposi sarcoma-associated herpesvirus infection
ccad05168
Herpes simplex virus 1 infection
ccad05169
Epstein-Barr virus infection
ccad05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
122440425 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
122440425 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
122440425 (TYK2)
04621 NOD-like receptor signaling pathway
122440425 (TYK2)
04658 Th1 and Th2 cell differentiation
122440425 (TYK2)
04659 Th17 cell differentiation
122440425 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
122440425 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
122440425 (TYK2)
05160 Hepatitis C
122440425 (TYK2)
05171 Coronavirus disease - COVID-19
122440425 (TYK2)
05164 Influenza A
122440425 (TYK2)
05162 Measles
122440425 (TYK2)
05168 Herpes simplex virus 1 infection
122440425 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
122440425 (TYK2)
05169 Epstein-Barr virus infection
122440425 (TYK2)
05165 Human papillomavirus infection
122440425 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
122440425 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccad01001
]
122440425 (TYK2)
Enzymes [BR:
ccad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
122440425 (TYK2)
Protein kinases [BR:
ccad01001
]
Non-receptor tyrosine kinases
JAK family [OT]
122440425 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
FERM_C_FAK1
ABC1
Kdo
Motif
Other DBs
NCBI-GeneID:
122440425
NCBI-ProteinID:
XP_043322616
LinkDB
All DBs
Position
4:92111788..92140762
Genome browser
AA seq
1187 aa
AA seq
DB search
MPLCQWRAATRGRKPSGDGAQPMATRGGLKVLLHWAGPSGGEPWVTFTEATLTAEDVCIH
IAHKVGITPPCFNLFALFDAQAQVWLPPNHILDTSRDSSLTLHFRMRFYFRNWHGTNPQE
PAVYRCGPPGSETSSEQAEQGVQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHF
QNESLGMALLHLCHLALHDGVPLEKVAKKTSFKDCIPRSFRRQIRQHNALTRLRQRSIFR
KFLRAFQPGCLSQQVVMVKYLATLERLAPRFGTERVPVCHLELLSLAEGEPCYIRDSGQA
LPDPGSESAAGPPTHEVLVSGTEGIRWRLVRAEGPGDGGGGGGSRMPDAGPSGKKMKAQK
AGSEPVDRPRETPWSYFCDFQDITHVVLKERHVSIHCQDNKCLELTLPSRAAALSLVSLV
DGYFRLTADSNHYLCHDVAPPRLVMSIQDGIHGPLLEPFVLAKLKPEAGLYLIHWSTSHL
HRLILTVAQRDQLQAPGTKGLRLRKFPIELRAGTVMLEGWGRSFPSVRDLRAALQDCSLR
AGDDCFSLRRCCLPRPGEISNLIVTRGPQASTRPLNLSHLSFYRIRQEDITQLSHLGQGT
RTNVYEGLLRVGGRGPEEDKADGEEPPVPAGDHGQKLRVVLKVLDPSHHDIALAFYETAS
LMSQVSHVHLVFVHGVFVHGSENIMVTEYVEHGPLDVWLRRERGRVPLAWKLAVAQQLAS
ALSYLEDKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLSALSREERVERIPWTA
PECLSGGAHSLSTAADKWGFGATLLEICFDGEAPLQGRSPSEKERFYQKQHKLPEPSCPE
LATLTSQCLTYEPAQRPSFRTILRDFTQLQPQNLADVLSVSPDSLASDPTVFNKRYLKKI
RDLGEGHFGKVSLYCYDPNNDGTGEMVAVKALKADCGPQLRSSWRREIDILRTLYHKHIV
KYKGCCEDQGEKSVQLVMEYMPLGSLRDYLPRHNVGLVQLLLFSLQICEGMAYLHTQHYV
HRDLAARNVLLDNNRLVKIGDFGLTKAVPEGHEYYCVREDGDSPVFWYAPECLKECKFYY
ASDVWSFGVLMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPQPERC
PSEIYSLMKDCWKAEASFRPTFQNLVPILRSYHEKYQGQAPSVFSVC
NT seq
3564 nt
NT seq
+upstream
nt +downstream
nt
atgcctttgtgccaatggagggccgccaccaggggcaggaagcccagtggggacggagct
cagcccatggccaccagaggaggcctgaaagtgcttctgcactgggctggccccagtggt
ggggagccctgggtcaccttcactgaggccacactgaccgcagaggacgtctgcatccac
atcgcacacaaagtcggcatcaccccaccctgcttcaatcttttcgccctcttcgatgcc
caggcccaggtctggctgcctccaaatcacatcctggatacctccagggactccagcctg
acgctgcacttccgcatgaggttttatttccgaaactggcatggcacgaatcctcaggag
ccggctgtgtaccgctgcgggcccccagggtccgagacttcctcagaacaggcagagcag
ggggtgcaactgctggaccctgcctcctttgagtacctctttgagcagggcaagcatgag
tttgtaaacgacgtggcatctctatgggagctgtctagcgaggaggagatccaccacttt
cagaatgagagcctgggcatggcccttttgcacctctgccaccttgctctccacgatggt
gtcccccttgagaaggtggccaagaagaccagcttcaaggattgtatcccacgctccttc
cggcggcagatccggcagcacaatgctctgacacgcctgcgccaacggagcatcttccgc
aagttcctacgggccttccagccgggctgcctctcccagcaggtcgtcatggtgaagtac
ctggccacgctcgagcgactggcaccccgctttggcacagagcgtgtgcccgtgtgccac
ctggagctgctgtccctggccgagggggagccctgctacatccgggacagtggccaggcc
cttcccgaccccgggtctgagtctgctgccggaccccccacccacgaggtgctggtgtca
ggcacagaaggcatccggtggcggctggtacgggcggaggggcctggtgatggtggcggt
ggtggcggcagcaggatgcccgatgctggcccatctgggaagaaaatgaaggcccagaag
gcgggcagcgagccagtggacaggcctcgggagaccccctggtcctacttttgcgacttc
caagacatcacccacgtggtgctgaaggaacgccacgtcagcatccattgtcaggacaac
aagtgcctggagctgaccctgccttcccgggctgcggccctgtccttggtgtcgctggtg
gatggttactttcgcctgaccgccgactccaaccactatctgtgccacgacgtggctcct
ccacggctggtgatgagcatccaggatggtatccacggacccctgctggagccatttgtg
ctggccaagctgaagcccgaggctggcctctaccttatccactggagcaccagccacctc
caccgcctcatcctcacagtggcccagcgcgaccagctccaggctcccggcaccaagggc
ttgcgcctgcggaagttccccattgagctccgggccgggacagtcatgctggagggctgg
ggccgatctttccccagcgtgcgggacctgcgggccgccctgcaggactgttcgctgcgg
gccggcgacgactgcttttccctgcgtcgctgctgcctgccccggccgggagagatctcc
aacctcatcgtcacacgtgggcctcaggccagcaccagaccgctcaatctcagtcatctc
agcttctaccggatccgccaggaagacatcacccagctgtcccacttgggccagggcaca
aggaccaacgtgtatgagggcctcttgcgagtagggggcagaggccccgaggaggacaag
gcggatggcgaggaaccccccgtgcccgctggggaccatgggcagaagctgcgtgtggta
ctcaaggtgctagaccccagtcaccacgacatcgccctggccttctacgagacagccagc
ctcatgagccaggtctcccacgtgcacctggtcttcgttcacggcgtcttcgtgcacggc
tccgagaacatcatggtcactgagtacgtggagcacgggcccctggacgtgtggctgcgg
cgggagaggggccgcgtgcccctggcctggaagttggcagtggcccagcagctggccagc
gccctcagctacctggaagacaaaagcctggttcatggcaacgtgtgtggccggaacatc
ctgctggcacggctggggctggcggagggcaccagccccttcatcaagctgagcgacccc
ggcgtgggcctgagtgccctctccagggaggagcgggtggagcggatcccctggacagcc
cccgagtgcctgtctggtggagcccacagcctgagcaccgcagccgacaagtggggcttt
ggtgccaccctcctggagatctgcttcgacggcgaggcccccctgcagggccgcagtccc
tctgagaaagagcgcttctaccagaagcagcacaaactgcccgagccttcgtgcccagag
ctggccactcttaccagccagtgcctgacctacgagccagcccagcggccgtccttccgc
accatcctgcgtgacttcactcagctacagccccagaatctcgctgatgtcttgtctgtg
agcccggattcactggcttcagatcccacggttttcaacaagagatatttgaaaaagatc
cgtgatctgggtgagggtcacttcggaaaggtcagcctgtattgctacgacccgaacaac
gacggcactggtgagatggtagccgtgaaggccctcaaggcagactgcggtccccagctc
cggtcgagctggaggcgagaaatcgacatcctacgcaccctctaccacaagcacatcgtc
aagtacaagggctgctgcgaggaccaaggcgagaagtcggtacagctggtcatggaatac
atgcccctgggcagtctccgagactacttgccccggcacaatgtcgggctggtccagctg
ctgctcttctccctgcagatctgcgagggcatggcctacctgcacacacagcactacgtg
catcgagacctggccgcgcgcaacgtgctgctggacaacaacaggctggtcaagatcggg
gacttcggcctcaccaaggccgtgcccgagggccacgagtactactgcgtgcgcgaggat
ggggacagtcctgtgttctggtatgccccggagtgcctgaaggagtgtaagttctactat
gcatcggacgtctggtcctttggggtccttatgtatgagctgctgacctactgtgactcc
agccagagccccccctcgaaattcatcgagctcataggcctcacccaggggcagatgact
gtgctgaggctcacggagctgctggaacgaggggagaggctgccacaaccagagagatgc
ccctctgagatctattccctcatgaaggactgctggaaggcagaggcctcattccgcccg
accttccagaacctcgtacccatcctcagatcataccacgagaaataccaaggccaggcc
ccctcagtgttcagtgtctgctga
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integrated database retrieval system
