Cervus canadensis (wapiti): 122441999 Help Entry 122441999         CDS       T07554                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism ccad  Cervus canadensis (wapiti) Pathway ccad00230   Purine metabolism ccad01100   Metabolic pathways ccad01522   Endocrine resistance ccad04015   Rap1 signaling pathway ccad04020   Calcium signaling pathway ccad04022   cGMP-PKG signaling pathway ccad04024   cAMP signaling pathway ccad04062   Chemokine signaling pathway ccad04072   Phospholipase D signaling pathway ccad04081   Hormone signaling ccad04082   Neuroactive ligand signaling ccad04114   Oocyte meiosis ccad04211   Longevity regulating pathway ccad04213   Longevity regulating pathway - multiple species ccad04261   Adrenergic signaling in cardiomyocytes ccad04270   Vascular smooth muscle contraction ccad04371   Apelin signaling pathway ccad04540   Gap junction ccad04611   Platelet activation ccad04713   Circadian entrainment ccad04714   Thermogenesis ccad04723   Retrograde endocannabinoid signaling ccad04724   Glutamatergic synapse ccad04725   Cholinergic synapse ccad04727   GABAergic synapse ccad04740   Olfactory transduction ccad04750   Inflammatory mediator regulation of TRP channels ccad04911   Insulin secretion ccad04912   GnRH signaling pathway ccad04913   Ovarian steroidogenesis ccad04914   Progesterone-mediated oocyte maturation ccad04915   Estrogen signaling pathway ccad04916   Melanogenesis ccad04918   Thyroid hormone synthesis ccad04921   Oxytocin signaling pathway ccad04923   Regulation of lipolysis in adipocytes ccad04925   Aldosterone synthesis and secretion ccad04926   Relaxin signaling pathway ccad04927   Cortisol synthesis and secretion ccad04928   Parathyroid hormone synthesis, secretion and action ccad04934   Cushing syndrome ccad04935   Growth hormone synthesis, secretion and action ccad04962   Vasopressin-regulated water reabsorption ccad04970   Salivary secretion ccad04971   Gastric acid secretion ccad04972   Pancreatic secretion ccad04976   Bile secretion ccad05032   Morphine addiction ccad05163   Human cytomegalovirus infection ccad05166   Human T-cell leukemia virus 1 infection ccad05200   Pathways in cancer ccad05207   Chemical carcinogenesis - receptor activation ccad05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ccad00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     122441999 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     122441999 (ADCY3)    04371 Apelin signaling pathway     122441999 (ADCY3)    04020 Calcium signaling pathway     122441999 (ADCY3)    04072 Phospholipase D signaling pathway     122441999 (ADCY3)    04024 cAMP signaling pathway     122441999 (ADCY3)    04022 cGMP-PKG signaling pathway     122441999 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     122441999 (ADCY3)    04081 Hormone signaling     122441999 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     122441999 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     122441999 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     122441999 (ADCY3)    04062 Chemokine signaling pathway     122441999 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     122441999 (ADCY3)    04923 Regulation of lipolysis in adipocytes     122441999 (ADCY3)    04912 GnRH signaling pathway     122441999 (ADCY3)    04913 Ovarian steroidogenesis     122441999 (ADCY3)    04915 Estrogen signaling pathway     122441999 (ADCY3)    04914 Progesterone-mediated oocyte maturation     122441999 (ADCY3)    04921 Oxytocin signaling pathway     122441999 (ADCY3)    04926 Relaxin signaling pathway     122441999 (ADCY3)    04935 Growth hormone synthesis, secretion and action     122441999 (ADCY3)    04918 Thyroid hormone synthesis     122441999 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     122441999 (ADCY3)    04916 Melanogenesis     122441999 (ADCY3)    04925 Aldosterone synthesis and secretion     122441999 (ADCY3)    04927 Cortisol synthesis and secretion     122441999 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     122441999 (ADCY3)    04270 Vascular smooth muscle contraction     122441999 (ADCY3)   09154 Digestive system    04970 Salivary secretion     122441999 (ADCY3)    04971 Gastric acid secretion     122441999 (ADCY3)    04972 Pancreatic secretion     122441999 (ADCY3)    04976 Bile secretion     122441999 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     122441999 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     122441999 (ADCY3)    04727 GABAergic synapse     122441999 (ADCY3)    04725 Cholinergic synapse     122441999 (ADCY3)    04723 Retrograde endocannabinoid signaling     122441999 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     122441999 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     122441999 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     122441999 (ADCY3)    04213 Longevity regulating pathway - multiple species     122441999 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     122441999 (ADCY3)    04714 Thermogenesis     122441999 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122441999 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     122441999 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     122441999 (ADCY3)    05163 Human cytomegalovirus infection     122441999 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     122441999 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     122441999 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     122441999 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     122441999 (ADCY3) Enzymes [BR:ccad01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      122441999 (ADCY3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Peptidase_S49_N Motif Other DBs NCBI-GeneID:  122441999 NCBI-ProteinID:  XP_043325157 LinkDB All DBs Position 5:70559283..70640986 Genome browser AA seq 1145 aa AA seqDB search MPRTQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSGDKLAPLAVAGVGLVLDII LFVLCKKGLLPNRVTRRVVPYLLWLLISAQVFSYLGLNFSRAHAASDTVGWQAFFIFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGVQLLREILANVFLYLCAIIVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGEGGSRCD YLEEKGIETYLIIASKPEVKKTAAQNGLSGSALLNGAPPSSKPSSPALIETKESNGSIHT SGSISEEPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTAAVEILIDPWLMTN YVTFVVGEALLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYTGPTNGTAEMQVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLIAGAVAVINIYAWCPIFDDYDRKRFQQHDFPMVALEKMQVFSSSGLNGTDRLPLVPSK YSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKEEKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGASITLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggacccagggcttctccgagcccgagtactcggcagagtactcggccgagtac tctgtcagcttgccttcggaccctgaccgcggggtgggccggacccatgaaatctctgtc cggaactcggggtcgtgcctctgcttgcctcgcttcatgcggctgaccttcgtaccagag tccttggagaacctgtaccagacctacttcaagaggcagcgccatgagaccctgctggtg ctggtggtcttcgcggccctcttcgactgctatgtggtggtcatgtgtgccgtggtcttc tctggcgacaagctggccccacttgctgtggctggggtcgggctggtgttggacattatc ctcttcgtgctctgcaaaaaggggctgctccctaaccgggtcactcggagagtggtcccc tacctgctgtggctgctgatatcagcccaggtcttctcctacctgggcctgaacttctcc cgtgcccacgcggccagcgacacggtgggctggcaggccttcttcatcttctccttcttc atcacgctgccactcagcctcagccccattgtcatcatctctgtggtctcctgcgtcgtg cacacgctcgtcttgggggtcaccgtggcccagcagcagcaggatgggctgaagggagtg cagttgctgagggagattctggccaacgtcttcctctacctgtgcgccatcatcgtgggc atcatgtcctactacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tctctggaggtgaagatgaacctggaggagcagagtcagcagcaggagaaccttatgctc tccatcctgcccaagcacgtggccgacgaaatgctgaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccacgagaacgtcagcatc ctctttgctgatatcgtgggcttcacccagctgtcctcagcctgcagcgcccaggagctt gtgaagctgctcaatgagctctttgcccgcttcgacaagctggcggctaaataccaccag ctgcggattaagatcctgggcgactgttactactgcatctgtgggctgcctgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgggaaaagacgaagactggggtggacatgcgagtgggggtgcacacgggcaccgtg ctggggggcgtcctcggccagaaacgctggcagtacgatgtgtggtccaccgacgtcacc gtggccaacaagatggaggctggcggcatcccggggcgcgtgcacatctcccagagcacc atggactgcctgaaaggagagttcgacgtggagccgggtgaggggggcagtcgctgtgat tacctggaagagaagggcatcgagacctacctcatcatcgcttccaagccagaggtgaag aagacagctgcccaaaacggcctcagtggctcggccctgctgaacggagcaccgccttcc tcaaagcccagctcccctgccctcattgagaccaaggagtccaacgggagcattcacacc agcggctctatatctgaggagccggaggagcaagatgcccaggccgacaacccctcgttc cccaaccctcgccggaggctgcgccttcaggacctggctgatcgcgtggtggacgcctct gaggacgagcatgagctcaaccagctgctcaacgaggcgctgctggagcgggagtctgcc caggtagtgaagaagagaaacaccttcctcctgtccatgcggttcatggaccccgagatg gaaacccgctactcggtggagaaggagaagcagagcggggctgccttcagttgctcctgc gtcgtcctgctctgcacggccgcggtggagatcctcattgacccctggctcatgacgaac tatgtgacctttgtggttggggaggctctgctcctgatcctgacgatctgctcgctggct gccatctttccgcgggcctttcctaagaagctcgtggccttctctacttggatcgaccgg acacgctgggccaggaacacctgggccatgctggccatcttcattctggtcatggcaaac gtggtggacatgctcagctgtctccagtactacacaggacccaccaacggcaccgcagag atgcaggtggaagatggctgcgtggagaaccccaagtattacaactatgtggccgtgctg tccctcatcgccaccatcatgctggtgcaggtcagccacatggtcaagctcacactcatg ctgctcattgcgggtgccgtggctgtcatcaacatctacgcctggtgccccatctttgac gactacgaccgcaaacgcttccagcaacacgactttccgatggtggccttagagaagatg caggtgttttccagctcggggctcaatggcactgacaggctgcccctggtgccgtctaag tactcgatgacagtgatgatcttcgtcatgatgctgagcttttactacttctcccgccat gtggaaaagctggcacggacactgttcttgtggaagattgaggtccatgaccagaaggaa cgtgtctatgagatgcgacgctggaatgaagccttggtcaccaacatgctgcctgagcac gtggcacgccatttcctggggtccaagaagagagatgaggaactgtacagccagtcttat gatgagattggagttatgtttgcctccctgcccaattttgctgacttctacacagaggag agcatcaataatggcggcattgaatgtctgcgcttcctcaatgagatcatctcagatttc gactctcttctggacaatcccaagttccgggtcatcaccaagatcaagaccattggtagc acctacatggcagcttcaggagtcaccccagatgtcaacaccaatggctttaccagctcc aacaaggaggagaagtcagacaaggaacgctggcagcacctggcagatctggccgatttt gcgctggccatgaaggacacgctcaccaacatcaacaaccagtccttcaacaacttcatg ctgcgcattggaatgaacaaaggaggggtcctggctggggtcattggagcccggaagcca cactacgacatctggggcaacacagtcaacgtggccagcaggatggagtccacaggggtc atgggcaacatccaggtggtggaagaaacccaagtcatccttcgagagtatggcttccgc ttcgtgaggagagggcccatctttgtgaaagggaagggggaactgctaaccttcttcttg aagggccgagacaagctggccaccttccccaatggcgcctcaatcacactgcctcaccag gtagtagacaactcctga

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