Cervus canadensis (wapiti): 122442195
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Entry
122442195 CDS
T07554
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad00790
Folate biosynthesis
ccad01100
Metabolic pathways
ccad01240
Biosynthesis of cofactors
ccad01523
Antifolate resistance
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
122442195 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
122442195 (FPGS)
Enzymes [BR:
ccad01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
122442195 (FPGS)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
122442195
NCBI-ProteinID:
XP_043325574
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Position
5:93547576..93575046
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AA seq
585 aa
AA seq
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MSRARCHALFLAAVSPRGATTGVAAQRGLSAWPVLQEPGMEYQDAVRTLNTLQTNANYLE
MVKRERGDPQTQLEAMKLYLARSGLQVEDLDQLNIIHITGTKGKGSTCAFTERILRSYGL
KTGFFSSPHLVQVRERIRINGQPISSELFTKHFWRLYHRLEETKDDSSCVSMPGYFRFLT
LMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGITSLGIDHTGLLGDTMEKIAWQ
KGGIFKSGVPAFTVPQPDEPLAVLRDRAQQISCPLYLCPPLQALEEGGPPLTLGLEGEHQ
RSNAALALQLARCWLQQKGYQDAGELKASRPSLPGQLPLAPVFQPTPHMQQGLWHTEWPG
RTQLLRRGPLTWYLDGAHTTSSMQACVRWFRQALHRCQRPDSGSEVRVLLFNSTGDRDSA
ALLKLLQPCQFDYAIFCPNLAEMASTDNADQQNFTVTLDQVLLRCLTHQQHWSRLHEEQA
SPDPWSTPSREQGGPASLLLAPHPPHTHSASSLIFSCISHALQWITQGRDPVFQPPRPPR
GLLTHPVADSGAVVLQEAAAVHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1758 nt
NT seq
+upstream
nt +downstream
nt
atgtctcgggcacgctgccacgctctcttcctggcagcggtttctccgcgtggtgcaaca
accggggtcgcagcgcagcgagggttgagcgcgtggcctgtgctgcaggagccaggcatg
gagtatcaggatgctgtgcgcacactcaacacactgcagaccaatgctaactacttggag
atggtgaagcgtgagcggggtgacccccagacacagctggaagccatgaagctgtacttg
gcacggagtgggctgcaggtggaggacttggaccaactgaacatcatccacatcactggg
accaaggggaagggctccacgtgtgccttcactgaacgtatcctccgaagctacggcctg
aagacggggttctttagctctccccacctggtgcaggtgcgtgagcggatccgcatcaat
gggcagcccataagctccgaactcttcaccaagcacttctggcgcctctaccaccggctg
gaggagaccaaggacgacagcagctgtgtctccatgcccggctacttccgcttcctcacg
ctcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtggaagtaggc
atcggtggggcttacgactgcaccaacatcatcaggaagcctgtggtgtgtgggatcacc
tctcttggcatcgaccacactggccttctcggggacacgatggagaagatcgcatggcag
aaagggggcatttttaagagtggcgtccctgccttcaccgtgccccagcctgacgagccg
ctggcagtgctaagggacagggctcagcagatctcatgtcccctctacctgtgcccacca
ctacaagccctggaggaaggggggccaccgctgaccctgggcctggagggagagcaccag
cggtccaatgctgccctggccttgcagctggcccgctgctggctgcagcagaaaggttac
caggatgccggggagctgaaggcatccaggcccagcctcccagggcagctgcccctggca
cctgtgttccagcccacaccccacatgcagcaggggctttggcacacggagtggccaggt
cggacgcagttgctgcggcgcgggccccttacctggtacctggacggcgctcacaccacc
agcagcatgcaggcctgcgtgcgctggttccgccaggcgctgcaccgatgccagaggccg
gacagcgggtccgaggtgcgcgtcttgctcttcaactccactggggaccgggattccgcg
gccctgctgaagctgctgcagccctgccagtttgactatgccattttctgccctaacctg
gcagagatggcatcaacagacaatgcagaccaacagaacttcacagtgacactggaccag
gtgctgctccgctgcctcacccaccaacagcactggagtcgcctgcatgaggagcaggcc
agcccggacccctggagcacccccagccgggagcagggtgggcctgcatctctgctgctg
gcgcctcacccaccccacacccacagtgccagctccctcatcttcagctgcatctcccac
gccttgcagtggatcacccaaggccgggaccctgtctttcagccgccccgtcccccacgg
ggcctcctcacccaccctgtggcagacagcggggccgtggtactccaagaggctgccgcc
gtccacgtgctggtcacaggcagcctacacctggtgggcggtgtcctgaagctgctggag
ccctccctgtcccagtag
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