KEGG   Cervus canadensis (wapiti): 122446399
Entry
122446399         CDS       T07554                                 
Symbol
PPP3CB
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
ccad  Cervus canadensis (wapiti)
Pathway
ccad04010  MAPK signaling pathway
ccad04020  Calcium signaling pathway
ccad04022  cGMP-PKG signaling pathway
ccad04114  Oocyte meiosis
ccad04218  Cellular senescence
ccad04310  Wnt signaling pathway
ccad04360  Axon guidance
ccad04370  VEGF signaling pathway
ccad04380  Osteoclast differentiation
ccad04625  C-type lectin receptor signaling pathway
ccad04650  Natural killer cell mediated cytotoxicity
ccad04658  Th1 and Th2 cell differentiation
ccad04659  Th17 cell differentiation
ccad04660  T cell receptor signaling pathway
ccad04662  B cell receptor signaling pathway
ccad04720  Long-term potentiation
ccad04724  Glutamatergic synapse
ccad04728  Dopaminergic synapse
ccad04921  Oxytocin signaling pathway
ccad04922  Glucagon signaling pathway
ccad04924  Renin secretion
ccad05010  Alzheimer disease
ccad05014  Amyotrophic lateral sclerosis
ccad05020  Prion disease
ccad05022  Pathways of neurodegeneration - multiple diseases
ccad05031  Amphetamine addiction
ccad05152  Tuberculosis
ccad05163  Human cytomegalovirus infection
ccad05166  Human T-cell leukemia virus 1 infection
ccad05167  Kaposi sarcoma-associated herpesvirus infection
ccad05170  Human immunodeficiency virus 1 infection
ccad05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ccad05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122446399 (PPP3CB)
   04310 Wnt signaling pathway
    122446399 (PPP3CB)
   04370 VEGF signaling pathway
    122446399 (PPP3CB)
   04020 Calcium signaling pathway
    122446399 (PPP3CB)
   04022 cGMP-PKG signaling pathway
    122446399 (PPP3CB)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    122446399 (PPP3CB)
   04218 Cellular senescence
    122446399 (PPP3CB)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    122446399 (PPP3CB)
   04650 Natural killer cell mediated cytotoxicity
    122446399 (PPP3CB)
   04660 T cell receptor signaling pathway
    122446399 (PPP3CB)
   04658 Th1 and Th2 cell differentiation
    122446399 (PPP3CB)
   04659 Th17 cell differentiation
    122446399 (PPP3CB)
   04662 B cell receptor signaling pathway
    122446399 (PPP3CB)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    122446399 (PPP3CB)
   04921 Oxytocin signaling pathway
    122446399 (PPP3CB)
   04924 Renin secretion
    122446399 (PPP3CB)
  09156 Nervous system
   04724 Glutamatergic synapse
    122446399 (PPP3CB)
   04728 Dopaminergic synapse
    122446399 (PPP3CB)
   04720 Long-term potentiation
    122446399 (PPP3CB)
  09158 Development and regeneration
   04360 Axon guidance
    122446399 (PPP3CB)
   04380 Osteoclast differentiation
    122446399 (PPP3CB)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    122446399 (PPP3CB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    122446399 (PPP3CB)
   05170 Human immunodeficiency virus 1 infection
    122446399 (PPP3CB)
   05163 Human cytomegalovirus infection
    122446399 (PPP3CB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122446399 (PPP3CB)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    122446399 (PPP3CB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122446399 (PPP3CB)
   05014 Amyotrophic lateral sclerosis
    122446399 (PPP3CB)
   05020 Prion disease
    122446399 (PPP3CB)
   05022 Pathways of neurodegeneration - multiple diseases
    122446399 (PPP3CB)
  09165 Substance dependence
   05031 Amphetamine addiction
    122446399 (PPP3CB)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122446399 (PPP3CB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:ccad01009]
    122446399 (PPP3CB)
Enzymes [BR:ccad01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     122446399 (PPP3CB)
Protein phosphatases and associated proteins [BR:ccad01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     122446399 (PPP3CB)
SSDB
Motif
Pfam: Metallophos DUF5378
Other DBs
NCBI-GeneID: 122446399
NCBI-ProteinID: XP_043332519
LinkDB
Position
8:64140943..64189076
AA seq 534 aa
MAAPEPARAAPPPPPPPPPPPGADRVVKAVPFPPTHRLTSEEVFDMDGIPRVDVLKNHLV
KEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANT
RYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYS
ERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLL
WSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMY
RKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFT
WSLPFVGEKVTEMLVNVLSICSDDELMTEGEDQFDERLIYGNKKVGSAAARKEIIRNKIR
AIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGGRQTLQSATVEAIEAEKAIRGF
SPPHRICSFEEAKGLDRINERMPPRKDAVQQDGFNSLNTAHATENHGTGNHGAQ
NT seq 1605 nt   +upstreamnt  +downstreamnt
atggccgccccggagccggcccgggctgcaccgcccccacccccgcccccgccgccccct
cccggggctgaccgcgtcgtcaaagctgttcctttccccccaacacatcgcttgacatct
gaagaagtatttgatatggatgggatacccagggttgatgttctgaagaaccacttagta
aaagaaggtcgggtagatgaagaaattgcacttagaattatcaatgagggtgctgccatt
cttcggagagagaaaaccatgatagaagtagaggctccaattacagtgtgtggtgacatc
catggccaattttttgatctgatgaaactttttgaagtaggaggatcacctgctaataca
cgatacctttttcttggtgattatgtggacagaggttattttagtatagagtgtgtctta
tatttatgggtcctgaagattctatatccaagtacattatttcttctgagaggcaaccat
gaatgcagacaccttactgaatattttacctttaagcaagaatgtaaaattaaatattca
gaaagagtctatgaagcttgtatggaagcttttgatagcttgcctcttgctgcactttta
aaccaacaatttctttgtgttcatggtggactttcaccagaaatacacacactggatgat
attaggagattagatagattcaaagagccacctgcatttggaccaatgtgtgacttgcta
tggtccgatccttctgaagattttggaaatgaaaaatcacaggaacattttagtcacaat
acagttcgaggatgttcttatttttataactatccagcagtgtgtgaatttttgcaaaac
aataatttgttatcgattattagagctcatgaagctcaagatgcaggctatagaatgtac
agaaaaagtcaaactacagggttcccttcattaataacaattttttcggcacctaattac
ttagatgtctacaataataaagctgctgtattaaagtatgaaaataatgtgatgaatatt
cgacagtttaactgttctccacatccttactggttgcccaattttatggatgttttcaca
tggtctttaccttttgttggagaaaaagtgacagaaatgttggtaaacgttctgagtatt
tgctctgatgatgaacttatgactgaaggcgaagaccagtttgatgaacggctcatatat
ggcaataaaaaagtaggttcagctgcagcccggaaagaaatcataagaaataaaattcga
gcaattggcaagatggcaagggtcttctctgttctcagggaggagagtgaaagtgtgctg
acactcaagggcctgactcccacagggatgttgcctagtggagtgttggctggaggacgg
cagaccctgcaaagtgccacagttgaggctattgaggctgaaaaagcaatacgaggattc
tctccaccacatagaatctgcagttttgaagaggcaaagggtttggataggatcaatgag
agaatgccaccccggaaagatgctgtacagcaagatggtttcaattctctgaacaccgca
catgccactgagaaccacgggactggcaaccatggtgcccagtga

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