Cervus canadensis (wapiti): 122446493
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Entry
122446493 CDS
T07554
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad00760
Nicotinate and nicotinamide metabolism
ccad01100
Metabolic pathways
ccad04068
FoxO signaling pathway
ccad04148
Efferocytosis
ccad04152
AMPK signaling pathway
ccad04211
Longevity regulating pathway
ccad04213
Longevity regulating pathway - multiple species
ccad04218
Cellular senescence
ccad04310
Wnt signaling pathway
ccad04922
Glucagon signaling pathway
ccad04936
Alcoholic liver disease
ccad05031
Amphetamine addiction
ccad05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
122446493 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
122446493 (SIRT1)
04068 FoxO signaling pathway
122446493 (SIRT1)
04152 AMPK signaling pathway
122446493 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
122446493 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
122446493 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
122446493 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
122446493 (SIRT1)
04213 Longevity regulating pathway - multiple species
122446493 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
122446493 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
122446493 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122446493 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ccad03036
]
122446493 (SIRT1)
03029 Mitochondrial biogenesis [BR:
ccad03029
]
122446493 (SIRT1)
Enzymes [BR:
ccad01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
122446493 (SIRT1)
Chromosome and associated proteins [BR:
ccad03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
122446493 (SIRT1)
Mitochondrial biogenesis [BR:
ccad03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
122446493 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
122446493
NCBI-ProteinID:
XP_043332743
LinkDB
All DBs
Position
8:complement(69098701..69125493)
Genome browser
AA seq
737 aa
AA seq
DB search
MADEAALALQPGGSPSVVAAEREAPSPPTGEPLRKRPRRDGPGVGRGPGEPAGTAPEREL
PAAAGGCPAAAAALWREAQVAAAAAAAGEGDNGPGLQGLSREAPPADDFYDDDDDEGEEE
EEAAAAAIGYRDNLLFGDEIITNGFHSCESDEDDRASHASSSDWTPRPRIGPYTFVQQHL
MIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQE
CKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAIDFPDLPDPQAMFDIEYFRKDPRPFFKF
AKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCL
ICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDE
VDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHR
LGGEYAKLCCNPVKLSEITEKPPRIQKELAHLSELPPTPLNISEGSSSPERTSPPDSSVI
VTLLDQETKSNVDDPDVSESKDCVTEKSQEVQTSTRSTESVNDQLESPDLKNAVSNTGEK
TERTSGAETVRRCWPARLAKEQISKRLDDNQYLFIPPNRYIFHGAEVYSDSEDDVLSSSS
CGSNSDSGTCQSPSLEEPMEDESENEEFYNGLEDDADVDERAGGTVFEADGGDQEAVNEA
ISMKQEATCINYPSNKS
NT seq
2214 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgcccttcagcccggaggctccccctcggtagtggcggct
gagagggaggccccgtcgccgcctactggggagccgctccgcaagaggccgcgaagagac
ggccccggcgtcgggcggggcccgggcgagcccgctgggacggcccccgagcgggaactg
ccggcggcggccggcggctgcccggcggcggcagcggcgctgtggcgggaggcccaggtg
gcggcggcggcggcggcggccggagaaggagacaatgggccgggcttacagggcctatcc
cgggaggcgccaccggccgacgacttctacgacgacgacgacgacgagggcgaggaggag
gaagaggcggcggcggcggctattgggtaccgagataaccttctgtttggtgatgaaatc
atcaccaatggttttcattcatgtgaaagtgacgaagatgatagagcctcgcatgcgagt
tctagtgactggactccaagacctcggataggtccatatacttttgttcagcaacatctc
atgattggcacagatcctcgaacaattcttaaagatttactaccagaaacaattcctcca
cctgaattggatgatatgacgctgtggcagattgttattaatatcctttcagaaccacca
aaaaggaaaaaaaggaaagatattaatacaattgaagatgctgtgaaattactgcaagag
tgcaaaaaaattatagttctaactggagctggggtttctgtttcttgtggaatacctgac
ttcaggtcaagagacggtatttatgctcgccttgcaatagactttccagaccttccagat
cctcaagcaatgtttgatattgaatatttcagaaaagatccaagaccattcttcaagttt
gcaaaggaaatatatcctggacaattccaaccatctctttgtcacaaattcatagccttg
tctgataaggaaggaaaactacttcgcaactatactcagaacatagatacactggagcag
gttgcaggaatccaaaggataattcagtgtcatggttcctttgcaacagcatcttgcctg
atttgtaaatataaagttgactgtgaagctgtacgaggagatattttcaatcaggtagtt
cctcgatgtcctagatgcccagctgatgaaccgcttgctatcatgaaaccagagattgtc
ttttttggtgaaaatttaccagaacagtttcatagagccatgaagtatgacaaagatgaa
gttgatcttctcattgttattggatcttccctgaaagtaagaccggtagcactaattcca
agttccataccccatgaagtgcctcagatattaattaatagggaacctttgcctcatctg
cattttgatgtagagcttcttggagactgtgacgtaattattaatgaactgtgtcatagg
ttaggtggtgaatatgccaaactttgctgtaaccctgtgaagctttcagaaattaccgag
aaacctcctcgaatacaaaaagagttggcacatttgtcagaattgccacccacacccctc
aatatttcagaaggctcaagttcacctgaaagaacttcaccaccagattcttcagtgatt
gtcactcttttagaccaagaaacaaagagtaatgttgatgatccagatgtgtctgaatca
aaagactgtgtcacagaaaaatcacaggaagtacagacttctactaggagcactgaaagt
gttaatgaccagttggagagtccagatttgaagaatgctgtctccaatactggtgagaaa
actgaaagaacttcaggtgctgaaacagtgagaagatgctggccggctagacttgcaaag
gagcagattagtaaacgccttgatgataatcagtatctgtttataccaccaaaccgttac
attttccatggcgctgaggtatattcagactctgaagatgatgtcttatcctctagttct
tgcggcagtaacagtgatagtggaacatgccagagtccaagtttagaagaacccatggag
gatgaaagtgagaatgaagaattttacaatggtttggaagatgacgctgatgttgatgag
agagccggaggaactgtatttgaagctgatggaggtgatcaagaggcagttaatgaagct
atatccatgaaacaggaagcaacatgcattaactatccatcaaacaaatcataa
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