Cervus canadensis (wapiti): 122454848
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Entry
122454848 CDS
T07554
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
ccad
Cervus canadensis (wapiti)
Pathway
ccad01521
EGFR tyrosine kinase inhibitor resistance
ccad01522
Endocrine resistance
ccad04010
MAPK signaling pathway
ccad04014
Ras signaling pathway
ccad04015
Rap1 signaling pathway
ccad04066
HIF-1 signaling pathway
ccad04068
FoxO signaling pathway
ccad04081
Hormone signaling
ccad04114
Oocyte meiosis
ccad04140
Autophagy - animal
ccad04144
Endocytosis
ccad04150
mTOR signaling pathway
ccad04151
PI3K-Akt signaling pathway
ccad04152
AMPK signaling pathway
ccad04211
Longevity regulating pathway
ccad04213
Longevity regulating pathway - multiple species
ccad04510
Focal adhesion
ccad04520
Adherens junction
ccad04550
Signaling pathways regulating pluripotency of stem cells
ccad04730
Long-term depression
ccad04913
Ovarian steroidogenesis
ccad04914
Progesterone-mediated oocyte maturation
ccad05200
Pathways in cancer
ccad05202
Transcriptional misregulation in cancer
ccad05205
Proteoglycans in cancer
ccad05214
Glioma
ccad05215
Prostate cancer
ccad05218
Melanoma
ccad05224
Breast cancer
ccad05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
ccad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122454848 (IGF1R)
04014 Ras signaling pathway
122454848 (IGF1R)
04015 Rap1 signaling pathway
122454848 (IGF1R)
04066 HIF-1 signaling pathway
122454848 (IGF1R)
04068 FoxO signaling pathway
122454848 (IGF1R)
04151 PI3K-Akt signaling pathway
122454848 (IGF1R)
04152 AMPK signaling pathway
122454848 (IGF1R)
04150 mTOR signaling pathway
122454848 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
122454848 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122454848 (IGF1R)
04140 Autophagy - animal
122454848 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
122454848 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
122454848 (IGF1R)
04520 Adherens junction
122454848 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
122454848 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
122454848 (IGF1R)
04914 Progesterone-mediated oocyte maturation
122454848 (IGF1R)
09156 Nervous system
04730 Long-term depression
122454848 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
122454848 (IGF1R)
04213 Longevity regulating pathway - multiple species
122454848 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122454848 (IGF1R)
05202 Transcriptional misregulation in cancer
122454848 (IGF1R)
05205 Proteoglycans in cancer
122454848 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
122454848 (IGF1R)
05214 Glioma
122454848 (IGF1R)
05218 Melanoma
122454848 (IGF1R)
05215 Prostate cancer
122454848 (IGF1R)
05224 Breast cancer
122454848 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
122454848 (IGF1R)
01522 Endocrine resistance
122454848 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccad01001
]
122454848 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ccad04090
]
122454848 (IGF1R)
Enzymes [BR:
ccad01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
122454848 (IGF1R)
Protein kinases [BR:
ccad01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
122454848 (IGF1R)
CD molecules [BR:
ccad04090
]
Proteins
122454848 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
122454848
NCBI-ProteinID:
XP_043345434
LinkDB
All DBs
Position
17:64141918..64442282
Genome browser
AA seq
1367 aa
AA seq
DB search
MKSSSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTETHECCHPECLGSCS
APDNATACVACRHYYYAGVCVPSCPPSTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNAIFVPRPERKRREVMQIANTTVSSRSRNTTVLDTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWSEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLSRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLIIALPIAVLLIVGGLLMMLYVFHR
KRNSSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPALAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSVKDEMEAGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASAASLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctagctccggaggagggtccccgacctcgctgtggggactcctgtttttctcc
gccgcgctctcgctctggcccacgagtggagaaatctgcgggccgggcatcgacatccgc
aacgactaccagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatttccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcctgggcgacctcttc
cccaacctcacggtcatccgcggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggacatcgggctctacaacctgcggaacatcacccgtggggcc
atccggatcgagaagaacgccgacctttgctacctctccacggtggactggtccctgatc
ctggacgccgtttccaacaactacatcgtggggaacaagcctcccaaggagtgtggggac
ctgtgcccgggcacgatggaggagaagccgctgtgtgagaagacgaccatcaacaacgag
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgccccagcgcgtgcggg
aagcgggcgtgcacggagacccacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcccgacaacgccacggcctgcgtggcctgccgccactactactatgccggcgtctgc
gtgcccagctgcccgcccagcacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccaacgccgagagcagcgactccgagggcttcgtcatccacgac
ggcgagtgcatgcaggagtgcccgtcgggcttcatccgcaacgggagccagagcatgtac
tgcatcccttgcgaaggcccttgtcccaaagtgtgtgaggaagaaaagaagacgaagacc
attgattctgtcacttctgctcagatgctccaaggatgcaccatcttcaaaggcaatctg
ctcatcaacatccgacgcggcaacaacatcgcttcggaactggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccggcactcccacgccttggtctccttgtcc
ttcctgaagaacctgcgccagatcctaggggaggagcagcttgaggggaactactccttc
tacgtccttgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaagctgggaaaatgtactttgcattcaatcccaaattgtgtgtctcggagatttac
cgcatggaggaagtgacggggacgaaagggcgccagagcaaaggggacataaacaccagg
aacaacggggagcgagcctcctgtgaaagtgacgtcctgcacttcacctccaccaccacg
tggaagaaccggatcatcatcacctggcaccggtaccggccccccgactaccgggacctc
atcagcttcaccgtctactacaaggaagccccctttaaaaacgtcacggagtatgatggg
caggacgcctgcggctccaacagctggaacatggtggacgtggacctgccgcccaacaag
gacgtggagcccggcatcttgctgcacgggctgaagccctggacacagtacgccgtttac
gtcaaggccgtgaccctcaccatggtggagaatgaccacatccgtggggccaagagcgag
atcttgtacattcgcaccaacgcctcagttccttccatccccctggatgtcctctcggcc
tcaaactcctcttctcagctgatcgtgaagtggaacccgccctccctgcccaacggcaac
ctgagctactacatcgtgcgctggcaacgccagccccaggacagctacctgtatcggcat
aactactgctccaaagacaaaatccccatcaggaagtacgccgacggcaccatcgacgtc
gaggaggtgacggagaaccccaagaccgaggtgtgcggcggggagaaagggccgtgctgt
gcttgccccaaaaccgaagccgagaagcaggcggagaaggaggaggctgaataccgcaag
gtcttcgagaacttcctgcacaacgccatcttcgtgcccagacccgaacggaagcggagg
gaggtcatgcagatcgccaacaccactgtgtccagccggagcaggaacaccacagtgctg
gacacctacaacatcacagacccggaagagctcgagactgagtacccttttttcgagagc
agagtggacaacaaggagagaactgtcatctccaacctccggccttttactctgtaccga
atcgacatccacagctgtaaccacgaggctgagaagcttggctgcagcgcctccaacttt
gtctttgcgagaacgatgcctgcagaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgagaactccatctttttaaaatggtcagaacctgagaatcccaatgga
ttgatcctcatgtatgaaataaaatatggatcccaagtcgaggatcagcgggaatgtgtg
tccagacaggagtacaggaagtacggcggggccaagctcagccggctcaacccgggcaac
tacacagcccgcatccaggccacctctctctctgggaacgggtcgtggaccgatcccgtg
ttcttctacgttcaggccaagacaacgtatgagaacttcatccacctgatcatcgctctg
cccattgcggttctgttgatagtgggagggttgcttatgatgctgtatgtcttccataga
aaaagaaatagcagcaggctgggaaatggagtgctgtatgcctctgtgaacccggagtat
ttcagcgcagctgatgtgtacgtgcctgacgagtgggaggtggcccgggagaagatcacc
atgagccgggagctgggccagggctcctttgggatggtctacgaaggcgtggccaagggc
gtggtcaaggatgagcccgagaccagggtggccattaagacggtgaacgaggccgccagc
atgcgcgagcggattgagtttctcaacgaggcctcggtgatgaaggagttcaactgccac
cacgtggtgcgcttgctgggcgtggtgtcccagggccagccgacgctggtcatcatggaa
ctgatgacccggggggacctcaaaagttatctccggtctctgaggccagaaatggagaat
aatccagcgctcgcacctcccagcctgagcaaaatgatccagatggctggcgagatcgca
gacggcatggcgtacctcaacgccaataagtttgtccacagagacctcgctgcccgcaac
tgcatggtggccgaagacttcacagtcaaaatcggagattttgggatgacgagagacatc
tatgagacagactattaccggaaaggggggaaggggctgctgcccgtccgctggatgtcc
cccgagtccctcaaggacggagtcttcaccactcactctgacgtctggtcctttggggtt
gtcctctgggagatcgccacgctggccgagcagccgtaccagggcctgtccaacgagcag
gtccttcgcttcgtcatggagggtggccttctggacaagccggacaactgtcctgacatg
ctgtttgagctgatgcgcatgtgctggcaatacaaccccaaaatgcggccttcgttcctg
gagatcatcagcagcgtcaaggacgagatggaggcgggcttccgggaggtctccttctac
tacagcgaggagaacaagcccccggagccggaggagctggacctggagcccgagaacatg
gagagtgtgccgctggatccctcggcctccgcggcctccctgccgctgcccgacagacac
tcaggacacaaggccgagaacggcccgggcccgggcgtgctggtcctacgggccagcttc
gatgagaggcagccctacgcgcacatgaacgggggccgcaagaacgagcgcgccctgccc
ctgccccagtcctcgacctgctga
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