Castor canadensis (American beaver): 109674432
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Entry
109674432 CDS
T04791
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan04140
Autophagy - animal
ccan04141
Protein processing in endoplasmic reticulum
ccan04210
Apoptosis
ccan04932
Non-alcoholic fatty liver disease
ccan05010
Alzheimer disease
ccan05012
Parkinson disease
ccan05014
Amyotrophic lateral sclerosis
ccan05016
Huntington disease
ccan05017
Spinocerebellar ataxia
ccan05022
Pathways of neurodegeneration - multiple diseases
ccan05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
109674432
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
109674432
09143 Cell growth and death
04210 Apoptosis
109674432
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
109674432
05012 Parkinson disease
109674432
05014 Amyotrophic lateral sclerosis
109674432
05016 Huntington disease
109674432
05017 Spinocerebellar ataxia
109674432
05022 Pathways of neurodegeneration - multiple diseases
109674432
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
109674432
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
109674432
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccan01001
]
109674432
Enzymes [BR:
ccan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
109674432
Protein kinases [BR:
ccan01001
]
Serine/threonine kinases: Other
IRE family
109674432
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
109674432
NCBI-ProteinID:
XP_020006983
UniProt:
A0A8B7THF8
LinkDB
All DBs
Position
Unknown
AA seq
967 aa
AA seq
DB search
MDRLFCILLQIFVSTSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPVLQVPTHV
EEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKKQDIWYVI
DLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFDYAASLPE
DDVNYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWHREGLRKVMHINVAVE
TLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVHEGVAVVP
RGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNYWLLIGHHETP
LSASTKMLERFPNNLPKHRENVIPADLEKKNFEEVINLVDQTSENAPITLSQDMEEKLAP
APAKPEAPVDSMLKDMATIILSTFLLVGWVAFIITYPLSMHQQHQLQHQQFQKELKKIQL
LQQQQLPFHPHGDTAQDADLLDTSGPYSESSGTSSPSPSPRASNHSLHSSSSASKAGSSP
SLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPECFSFAD
REVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGLEPITLLQ
QTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRHSFSRRSG
VPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGAC
SLDCFHPDKHEDVVARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIE
KESLDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHH
YRELPMDVRETLGSLPDDFVRYFTSRFPHLLSHTYQAMELCRHERLFQPYYFHEPPDPQP
PVTTDAL
NT seq
2904 nt
NT seq
+upstream
nt +downstream
nt
atggatcgattgttctgtatcctgttacagatttttgtaagtaccagcacagtgacactg
cctgaaaccttgctgtttgtttcaaccctggatggaagtttgcatgctgtcagcaagaga
acagggtcgatcaagtggactttaaaagaagatccagtcctgcaggtaccaacacacgtg
gaagagcctgcattcctcccggaccccaatgatggcagtctgtatacacttggaggcaag
aacaatgaaggccttacgaaacttccctttactattccggaactggtacaggcatcccca
tgccgaagttcagatggaatcctctacatgggtaaaaagcaggacatttggtatgtcatc
gacctcctgactggtgagaaacagcagactttatcatcagcctttgcagatagtctctgc
ccatcaacttctcttctgtatctcggtcggacagaatacaccatcaccatgtatgacacc
aaaacccgtgagctccgctggaacgccacctactttgactatgcagcctcactgcccgaa
gatgatgtaaactacaagatgtcccactttgtgtccaatggcgatggactggtggtaact
gtggacagtgaatctggggatgtcttgtggatccaaaactatgcctctccagtggtagcc
ttctatgtctggcatcgggagggcctgaggaaggtgatgcacatcaatgtcgctgtggaa
acactgcgctacttgaccttcatgtctggcgaggtggggcgcatcaccaagtggaagtac
ccattccccaaggagacagaggccaagagcaagctgacgcccaccctgtatgttgggaag
tactccaccagtctgtacgcttccccgtccatggtacatgagggagtcgcggtcgtgccc
cgcggtagcactcttccattgctggaaggccctcagactgatggtgtcaccattggggac
aagggggagtgcgtgatcacacccagcacagacctcaaatttgaccctggactcaaaggg
aagagcaagctgaactacttgaggaattactggcttctcataggacaccatgaaacccca
ctgtctgcatctaccaagatgctggagagatttcccaacaatctgcccaaacaccgggaa
aatgtgattcctgctgatctggagaaaaagaactttgaggaagttatcaacctggttgac
cagacttcggaaaatgctccaattactctatctcaggatatggaagaaaagttggctcct
gctcctgccaagccagaggcccccgtggactccatgctcaaggacatggccaccatcatc
ctgagtaccttcttgctggtcggctgggtggccttcatcatcacctaccccctgagcatg
catcagcagcaccagctccagcaccagcagttccagaaggaattgaaaaaaatccagctc
ttgcagcagcagcagctgcccttccacccacatggagatacagcccaggatgccgattta
ctagacacatctggcccctactcagagagctcaggcaccagcagccctagcccatcaccc
agagcctccaaccactcactccactccagcagctctgcctccaaggctggttccagcccc
tccctagagcaagacgatgaggatgaggaaaccagcatggtgattgttgggaagatttca
ttctgtcccaaggatgtcctaggtcatggagctgagggcacaattgtataccggggtatg
tttgacaaccgcgatgtggccgtgaagaggatccttcctgagtgttttagcttcgcagac
cgtgaggtccagctgctgcgagaatcagatgagcacccaaacgtgatccgttacttctgc
acggagagggatcggcagttccagtacattgccattgagctgtgtgcggccaccttgcag
gagtatgtggaacagaaggactttgcccaccttggtctggagcccatcaccttgctgcag
caaaccacctcagggctggcacacctccattcccttaacattgttcacagagacctgaaa
ccccacaacattctcctctccatgcccaatgcacatggcaggatcaaggccatgatctct
gactttggcctttgcaagaagctggcagtgggcaggcacagcttcagccgccgttctggg
gtgcctggcaccgaaggctggattgctcctgagatgctgagcgaagactgcaaggagaac
cctacctatacagtggacatcttctctgcgggctgcgtcttttactacgtcatctccgag
ggtagccacccctttggcaagtctctgcagcgacaggccaacatccttctgggcgcctgc
agccttgattgtttccacccagacaagcatgaagatgttgttgcacgtgagttgatagag
aaaatgatcgcaatggatccccagcagcggccctcagcaaagcacgtactaaaacatcct
ttcttctggagcctagaaaagcagctccagttcttccaggacgtgagtgaccgaatagaa
aaggagtccctggatggcccaatagtgaggcagttagaaagaggcgggagagccgtggtg
aagatggattggcgggaaaacatcactgtccccctccagacagatctgcgtaaattcaga
acctacaaaggtggctctgtcagagacctcctccgagccatgagaaataagaagcaccac
taccgggagctccccatggatgtacgggagaccctgggctccctcccggatgactttgta
cgctacttcacatcgcgcttcccccacctcctctcacacacctaccaggccatggagctg
tgccgccatgagagactctttcagccctactacttccacgagccccccgatccccagccc
ccagtgactacagatgccctctga
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