Castor canadensis (American beaver): 109681555
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Entry
109681555 CDS
T04791
Symbol
Sirt1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan00760
Nicotinate and nicotinamide metabolism
ccan01100
Metabolic pathways
ccan04068
FoxO signaling pathway
ccan04148
Efferocytosis
ccan04152
AMPK signaling pathway
ccan04211
Longevity regulating pathway
ccan04213
Longevity regulating pathway - multiple species
ccan04218
Cellular senescence
ccan04310
Wnt signaling pathway
ccan04922
Glucagon signaling pathway
ccan04936
Alcoholic liver disease
ccan05031
Amphetamine addiction
ccan05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
109681555 (Sirt1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
109681555 (Sirt1)
04068 FoxO signaling pathway
109681555 (Sirt1)
04152 AMPK signaling pathway
109681555 (Sirt1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
109681555 (Sirt1)
09143 Cell growth and death
04218 Cellular senescence
109681555 (Sirt1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
109681555 (Sirt1)
09149 Aging
04211 Longevity regulating pathway
109681555 (Sirt1)
04213 Longevity regulating pathway - multiple species
109681555 (Sirt1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
109681555 (Sirt1)
09165 Substance dependence
05031 Amphetamine addiction
109681555 (Sirt1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
109681555 (Sirt1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ccan03036
]
109681555 (Sirt1)
03029 Mitochondrial biogenesis [BR:
ccan03029
]
109681555 (Sirt1)
Enzymes [BR:
ccan01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
109681555 (Sirt1)
Chromosome and associated proteins [BR:
ccan03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
109681555 (Sirt1)
Mitochondrial biogenesis [BR:
ccan03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
109681555 (Sirt1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
TPP_enzyme_M
DUF592
Bt_P21
Motif
Other DBs
NCBI-GeneID:
109681555
NCBI-ProteinID:
XP_020011955
UniProt:
A0A8B7U2S0
LinkDB
All DBs
Position
Unknown
AA seq
554 aa
AA seq
DB search
MIGTDPRTILKDLLPETLPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQE
CKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKF
AKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFAAASCL
ICKYKVDCEAVRGDIFNQVVPRCPRCPVDEPLAIMKPEIVFFGENLPEQFHRAMKYDKDE
VDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHR
LGGEYAKLCCNPVKLSEITEKPPRTQKDLIHLSELPPTPLHISEDSSSPERTSPPDSSVT
LALLDQATESNVDDLDVSDSKGCMEGKAQEVQTSPKNERIAMENPDLKDVGSSTGVKNER
ISVTETVKKCWPNRLPKEQISKRLDGNQFLFLPPNRYIFHGAEVYSDSEDDIISSSSCGS
NSDSGTCQSPSFEEPLEDESEIEEFYNGLEDDADVPDRAGEAGFGAEGGDQEPVNEAIPR
KQEATDMNYPSDKS
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
atgattggcacagaccctcgaacgattcttaaagatttactgccagaaacacttcctcca
cctgaattggatgatatgacactatggcagattgttattaatattctttcagaaccacca
aaaaggaaaaaaaggaaagacattaatacaattgaagatgctgtgaaactacttcaagag
tgcaaaaaaataatagttctgactggagctggggtatctgtctcatgtggaatacctgac
ttcaggtcaagagatggtatttatgctcgccttgcagtagacttcccagatcttccagat
cctcaagcaatgtttgatattgaatatttcaggaaagatccaagaccattcttcaagttt
gcaaaggaaatatatcctggacagttccaaccatctctgtgtcataaattcatagccttg
tcagataaggaaggaaaactgcttcgcaactatactcagaatatagacaccttggaacag
gtcgcaggaatccaaaggataattcagtgtcatggttcgtttgcagcagcatcttgcctg
atttgtaaatacaaagttgactgtgaagctgtacgaggagatatttttaatcaggtagtt
cctcgatgtcctaggtgtccagttgatgaaccacttgctatcatgaaaccagagattgtc
ttttttggtgaaaatttaccggaacagtttcatagagccatgaagtatgacaaagatgaa
gttgatctcctcattgttatcgggtcttccctgaaagtgagaccagtagcactgattcca
agttccataccccatgaagtgcctcagatattaattaacagggaaccactgcctcatctg
cattttgatgtagagctccttggagactgtgacgtcataattaatgaattgtgtcatagg
ttaggtggtgaatatgccaaactttgttgtaaccctgtaaagctttcagaaattactgag
aaacctccacgaacacaaaaagacttgattcatttatcagagttgccaccaacacctctt
catatttcggaagattcaagttcaccagaaagaacttcaccaccagattcttcagtgact
ctcgcacttttagaccaagcaactgagagtaatgttgatgatttagatgtgtctgattca
aaaggttgtatggaaggaaaagcacaggaagtacagacttctcctaaaaacgagagaatt
gccatggaaaacccagatttgaaggatgttggttccagtactggagtgaaaaatgaaaga
atttcagttactgaaacagtgaaaaaatgctggcccaatagacttccaaaggagcagatt
agtaagcggcttgatggtaatcagtttctatttttaccaccaaatcgttacattttccat
ggcgctgaggtatattcagactctgaagatgacatcatatcttctagttcatgtggcagt
aacagtgatagtggcacatgccagagtccaagttttgaggagcccttggaagatgaaagt
gagattgaagaattctacaatggcctagaagatgatgctgatgtcccagacagagctgga
gaagctggatttggggctgaaggaggtgatcaagagccagttaatgaagctatacccagg
aaacaggaagcaacagacatgaactatccatcagacaagtcataa
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integrated database retrieval system
