Castor canadensis (American beaver): 109681743
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Entry
109681743 CDS
T04791
Symbol
Atp2a2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan04020
Calcium signaling pathway
ccan04022
cGMP-PKG signaling pathway
ccan04024
cAMP signaling pathway
ccan04148
Efferocytosis
ccan04260
Cardiac muscle contraction
ccan04261
Adrenergic signaling in cardiomyocytes
ccan04380
Osteoclast differentiation
ccan04919
Thyroid hormone signaling pathway
ccan04972
Pancreatic secretion
ccan05010
Alzheimer disease
ccan05017
Spinocerebellar ataxia
ccan05022
Pathways of neurodegeneration - multiple diseases
ccan05410
Hypertrophic cardiomyopathy
ccan05412
Arrhythmogenic right ventricular cardiomyopathy
ccan05414
Dilated cardiomyopathy
ccan05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
109681743 (Atp2a2)
04024 cAMP signaling pathway
109681743 (Atp2a2)
04022 cGMP-PKG signaling pathway
109681743 (Atp2a2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
109681743 (Atp2a2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
109681743 (Atp2a2)
09153 Circulatory system
04260 Cardiac muscle contraction
109681743 (Atp2a2)
04261 Adrenergic signaling in cardiomyocytes
109681743 (Atp2a2)
09154 Digestive system
04972 Pancreatic secretion
109681743 (Atp2a2)
09158 Development and regeneration
04380 Osteoclast differentiation
109681743 (Atp2a2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
109681743 (Atp2a2)
05017 Spinocerebellar ataxia
109681743 (Atp2a2)
05022 Pathways of neurodegeneration - multiple diseases
109681743 (Atp2a2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
109681743 (Atp2a2)
05412 Arrhythmogenic right ventricular cardiomyopathy
109681743 (Atp2a2)
05414 Dilated cardiomyopathy
109681743 (Atp2a2)
05415 Diabetic cardiomyopathy
109681743 (Atp2a2)
Enzymes [BR:
ccan01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
109681743 (Atp2a2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
109681743
NCBI-ProteinID:
XP_020012184
UniProt:
A0A8B7TXG6
LinkDB
All DBs
Position
Unknown
AA seq
997 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKIMSVIREWGSGSDTLRCLALATHDSPLKREEMQLEDSVNFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGHEEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPAILE
NT seq
2994 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcacacacaaagacggtggaggaggtgctgggccacttcggtgtcaacgag
agcacagggctgagcctggagcaggtcaagaagctcaaggagagatggggctccaacgag
ttaccagcagaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagaccta
ctagttagaattttattgctggcagcatgtatatcttttgttttagcttggtttgaagaa
ggtgaagaaactattacagcctttgtagaaccttttgtaattctgttgatattagtagcc
aacgcaattgtgggtgtatggcaggaaagaaatgctgaaaatgcaatagaagcccttaag
gagtatgaacctgaaatgggcaaagtgtaccgacaggacagaaagagtgtacagcggatt
aaagctaaagacatagttcccggtgacattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctacaactctaagagttgaccagtcgattctc
actggtgaatcagtttcagtcatcaagcacactgaccctgtccctgacccacgagctgtc
aaccaagataagaagaacatgctcttttctggtacaaacattgctgctgggaaagctatg
ggagtggtggtggcaactggagtgaacactgaaattggcaagatccgagatgaaatggtt
gcaacggagcaggagagaacacctcttcagcagaaactagatgagtttggggagcagctt
tccaaggtcatctcactcatttgcattgcagtctggatcataaacatcgggcacttcaat
gacccagttcatgggggctcttggatcagaggtgctatctactactttaagattgcagtg
gccctggccgtcgctgccatccctgagggtctgcctgctgtcatcaccacctgcctggct
cttggaactcgaagaatggcaaagaaaaatgccattgttcgaagcctcccttctgtggaa
acccttggttgtacttctgttatctgctcagacaagacaggcacacttacaacgaaccag
atgtcagtctgcaggatgttcattttggacaaagttgaaggtgatacttgttcccttaat
gagtttaccataactggatcaacatacgcacccattggagaagtgcataaagatgataaa
ccagtgaattgtcatcaatatgatggtcttgtagaattagcaacaatttgtgctctctgt
aatgactctgctttggattacaatgaggcgaagggtgtgtatgaaaaagttggagaagct
acagagactgctctcacttgcctggtagagaagatgaatgtatttgataccgaattgaag
ggactttctaaaatagaacgtgcaaatgcctgcaactcggtcattaaacaactgatgaaa
aaagaatttactctggaattttcacgtgatagaaaatcaatgtcagtctactgtacacca
aacaaaccaagtaggacatccatgagcaagatgtttgtgaagggagctcctgaaggcgtc
atcgacaggtgcacccatattcgagttgggagtacaaaggtccccatgacccctggtgtc
aaacagaagatcatgtctgtcattcgggagtggggcagtggcagcgacacacttcggtgc
ctggccctggccactcacgacagcccactgaagagagaagagatgcagctggaggactct
gtcaacttcatcaaatacgagaccaatctgactttcgttggctgtgtgggcatgctggat
cctcctagaatcgaagtggcctcctctgtgaagttgtgccggcaagcaggcatccgcgtc
atcatgatcacaggagacaacaagggcaccgccgtggccatctgtcgccgcattggcatc
ttcgggcacgaggaggatgtgacgtcaaaggcgtttacaggtcgggagtttgatgaactt
agcccttcagcccagagagatgcctgcttgaatgcccgctgtttcgctagagttgagcct
tcccacaagtctaagatcgttgagtttcttcagtcttttgatgagatcacagctatgact
ggtgatggtgtgaatgatgcccctgctctgaagaaatctgagattggcattgccatgggc
tcaggcactgcagtggctaaaactgcttctgagatggtcctggcagatgacaacttctct
accatcgtggctgctgttgaggagggccgagccatttacaacaacatgaagcaattcatc
cgctacctcatctcatccaacgtgggagaggttgtctgtattttcctgacagcagccctc
gggtttcctgaggctttaattcctgtgcagctactctgggtcaatctggtgactgacggt
ctgcctgccactgcactggggttcaatcctcccgacctggacatcatgaacaaaccaccc
cggaaccccaaggaaccgctgatcagcgggtggctctttttccgttacctggccattggc
tgctatgttggtgctgccaccgtgggtgctgctgcatggtggttcatcgcggcggacggc
ggtccaagagtgaccttctatcagctgagtcacttcctgcagtgcaaagaagacaaccct
gactttgaaggagtggattgtgcaatctttgagtccccctacccaatgacaatggcgctc
tctgttctagtgaccatagagatgtgtaacgccctcaacagcttgtctgaaaaccagtcc
ttgctgaggatgcccccttgggagaatatctggctggtgggttccatctgcttgtccatg
tcactccacttcctgatcctctatgtggaacctttaccacttatcttccagatcacaccg
ctcaacctgacccagtggctgatggtgctgaaaatctccttgcctgtgattctcatggat
gagacgctcaagtttgtagcccgcaactacctggaacctgcaatactggagtaa
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