KEGG   Castor canadensis (American beaver): 109682021
Entry
109682021         CDS       T04791                                 
Name
(RefSeq) serine/threonine-protein kinase B-raf isoform X1
  KO
K04365  B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan01521  EGFR tyrosine kinase inhibitor resistance
ccan01522  Endocrine resistance
ccan04010  MAPK signaling pathway
ccan04012  ErbB signaling pathway
ccan04015  Rap1 signaling pathway
ccan04024  cAMP signaling pathway
ccan04062  Chemokine signaling pathway
ccan04068  FoxO signaling pathway
ccan04150  mTOR signaling pathway
ccan04270  Vascular smooth muscle contraction
ccan04510  Focal adhesion
ccan04650  Natural killer cell mediated cytotoxicity
ccan04720  Long-term potentiation
ccan04722  Neurotrophin signaling pathway
ccan04726  Serotonergic synapse
ccan04730  Long-term depression
ccan04810  Regulation of actin cytoskeleton
ccan04910  Insulin signaling pathway
ccan04914  Progesterone-mediated oocyte maturation
ccan04928  Parathyroid hormone synthesis, secretion and action
ccan04934  Cushing syndrome
ccan05010  Alzheimer disease
ccan05022  Pathways of neurodegeneration - multiple diseases
ccan05034  Alcoholism
ccan05160  Hepatitis C
ccan05161  Hepatitis B
ccan05200  Pathways in cancer
ccan05205  Proteoglycans in cancer
ccan05208  Chemical carcinogenesis - reactive oxygen species
ccan05210  Colorectal cancer
ccan05211  Renal cell carcinoma
ccan05212  Pancreatic cancer
ccan05213  Endometrial cancer
ccan05214  Glioma
ccan05215  Prostate cancer
ccan05216  Thyroid cancer
ccan05218  Melanoma
ccan05219  Bladder cancer
ccan05220  Chronic myeloid leukemia
ccan05221  Acute myeloid leukemia
ccan05223  Non-small cell lung cancer
ccan05224  Breast cancer
ccan05225  Hepatocellular carcinoma
ccan05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109682021
   04012 ErbB signaling pathway
    109682021
   04015 Rap1 signaling pathway
    109682021
   04068 FoxO signaling pathway
    109682021
   04024 cAMP signaling pathway
    109682021
   04150 mTOR signaling pathway
    109682021
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109682021
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109682021
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    109682021
   04062 Chemokine signaling pathway
    109682021
  09152 Endocrine system
   04910 Insulin signaling pathway
    109682021
   04914 Progesterone-mediated oocyte maturation
    109682021
   04928 Parathyroid hormone synthesis, secretion and action
    109682021
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    109682021
  09156 Nervous system
   04726 Serotonergic synapse
    109682021
   04720 Long-term potentiation
    109682021
   04730 Long-term depression
    109682021
   04722 Neurotrophin signaling pathway
    109682021
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109682021
   05205 Proteoglycans in cancer
    109682021
   05208 Chemical carcinogenesis - reactive oxygen species
    109682021
  09162 Cancer: specific types
   05210 Colorectal cancer
    109682021
   05212 Pancreatic cancer
    109682021
   05225 Hepatocellular carcinoma
    109682021
   05226 Gastric cancer
    109682021
   05214 Glioma
    109682021
   05216 Thyroid cancer
    109682021
   05221 Acute myeloid leukemia
    109682021
   05220 Chronic myeloid leukemia
    109682021
   05218 Melanoma
    109682021
   05211 Renal cell carcinoma
    109682021
   05219 Bladder cancer
    109682021
   05215 Prostate cancer
    109682021
   05213 Endometrial cancer
    109682021
   05224 Breast cancer
    109682021
   05223 Non-small cell lung cancer
    109682021
  09172 Infectious disease: viral
   05161 Hepatitis B
    109682021
   05160 Hepatitis C
    109682021
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109682021
   05022 Pathways of neurodegeneration - multiple diseases
    109682021
  09165 Substance dependence
   05034 Alcoholism
    109682021
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    109682021
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109682021
   01522 Endocrine resistance
    109682021
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccan01001]
    109682021
Enzymes [BR:ccan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     109682021
Protein kinases [BR:ccan01001]
 Serine/threonine kinases: TKL group
  RAF family [OT]
   109682021
SSDB
Motif
Pfam: RBD C1_1 zf-RING-like C1_2 Zn_ribbon_TiaS
Other DBs
NCBI-GeneID: 109682021
NCBI-ProteinID: XP_020012586
UniProt: A0A8B7TZQ2
LinkDB
Position
Unknown
AA seq 386 aa
MAALSGGGGAEQGQVLFNGDMEPEAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLD
KFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDISVSSSASMDTVTSSSSS
SLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALM
MRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLA
FCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEAS
LAETALTSGSSPSAPPSDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSA
PNVHINTIEPVNIDVSISSIARIKIP
NT seq 1161 nt   +upstreamnt  +downstreamnt
atggcggcgctgagcggcggcggcggcgcggagcagggccaggttctgttcaacggggac
atggagcccgaggccggcgccgcggcctcttcggctgcggaccctgccattccggaggag
gtgtggaatatcaagcaaatgattaagttgacacaggaacatatagaggccctattggac
aaatttggtggggagcataatccaccgtcaatatacctagaggcctatgaagaatacacc
agcaaactagatgctctccaacaaagagaacagcagttattggagtccctggggaatgga
actgacatttctgtttctagctctgcatcaatggacaccgttacatcttcttcctcttct
agcctttcagtgctgccttcatctctttcagtctttcaaaatcctacagatgtatcacgg
agcaaccccaagtcaccacaaaaacctattgttagagtcttcctgcccaacaaacagagg
acagtggtacctgcaaggtgtggagttacagtccgagacagtttaaagaaagcactgatg
atgagaggtcttatcccagagtgctgcgctgtttacagaattcaggatggagagaagaaa
ccaattggctgggacactgatatttcctggcttaccggggaggagttgcatgtagaagtg
ttggagaatgttccacttacaacacataactttgtacggaaaacttttttcaccttagca
ttttgtgacttttgtcgaaagctgcttttccagggtttccgctgtcagacatgtggttat
aaatttcaccaacgttgtagtacagaggttccactgatgtgtgttaattatgaccaactt
gatttgctgtttgtctccaagttctttgaacatcatccaataccacaggaggaggcctcc
ttagcagagactgcccttacatctggatcatccccttctgcacccccctcagactctatt
gggccccaaattctcaccagtccatctccttcaaaatccattccaattccacagcccttc
cgaccagcagatgaagatcatcgcaatcagtttgggcaacgggaccggtcctcgtcagct
ccaaatgtgcatataaacacaatagaacctgtcaatattgatgtaagtatatccagcatt
gctagaattaaaataccgtag

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