| Entry |
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| Name |
(RefSeq) serine/threonine-protein kinase B-raf isoform X1
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| KO |
| K04365 | B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] |
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| Organism |
ccan Castor canadensis (American beaver)
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| Pathway |
| ccan01521 | EGFR tyrosine kinase inhibitor resistance |
| ccan04650 | Natural killer cell mediated cytotoxicity |
| ccan04914 | Progesterone-mediated oocyte maturation |
| ccan04928 | Parathyroid hormone synthesis, secretion and action |
| ccan05022 | Pathways of neurodegeneration - multiple diseases |
| ccan05208 | Chemical carcinogenesis - reactive oxygen species |
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| Brite |
KEGG Orthology (KO) [BR:ccan00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109682021
04012 ErbB signaling pathway
109682021
04015 Rap1 signaling pathway
109682021
04068 FoxO signaling pathway
109682021
04024 cAMP signaling pathway
109682021
04150 mTOR signaling pathway
109682021
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
109682021
09142 Cell motility
04810 Regulation of actin cytoskeleton
109682021
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
109682021
04062 Chemokine signaling pathway
109682021
09152 Endocrine system
04910 Insulin signaling pathway
109682021
04914 Progesterone-mediated oocyte maturation
109682021
04928 Parathyroid hormone synthesis, secretion and action
109682021
09153 Circulatory system
04270 Vascular smooth muscle contraction
109682021
09156 Nervous system
04726 Serotonergic synapse
109682021
04720 Long-term potentiation
109682021
04730 Long-term depression
109682021
04722 Neurotrophin signaling pathway
109682021
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109682021
05205 Proteoglycans in cancer
109682021
05208 Chemical carcinogenesis - reactive oxygen species
109682021
09162 Cancer: specific types
05210 Colorectal cancer
109682021
05212 Pancreatic cancer
109682021
05225 Hepatocellular carcinoma
109682021
05226 Gastric cancer
109682021
05214 Glioma
109682021
05216 Thyroid cancer
109682021
05221 Acute myeloid leukemia
109682021
05220 Chronic myeloid leukemia
109682021
05218 Melanoma
109682021
05211 Renal cell carcinoma
109682021
05219 Bladder cancer
109682021
05215 Prostate cancer
109682021
05213 Endometrial cancer
109682021
05224 Breast cancer
109682021
05223 Non-small cell lung cancer
109682021
09172 Infectious disease: viral
05161 Hepatitis B
109682021
05160 Hepatitis C
109682021
09164 Neurodegenerative disease
05010 Alzheimer disease
109682021
05022 Pathways of neurodegeneration - multiple diseases
109682021
09165 Substance dependence
05034 Alcoholism
109682021
09167 Endocrine and metabolic disease
04934 Cushing syndrome
109682021
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109682021
01522 Endocrine resistance
109682021
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:ccan01001]
109682021
Enzymes [BR:ccan01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
109682021
Protein kinases [BR:ccan01001]
Serine/threonine kinases: TKL group
RAF family [OT]
109682021
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
386 aa
MAALSGGGGAEQGQVLFNGDMEPEAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLD
KFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDISVSSSASMDTVTSSSSS
SLSVLPSSLSVFQNPTDVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALM
MRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLA
FCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEAS
LAETALTSGSSPSAPPSDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSA
PNVHINTIEPVNIDVSISSIARIKIP |
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| NT seq |
1161 nt +upstreamnt +downstreamnt
atggcggcgctgagcggcggcggcggcgcggagcagggccaggttctgttcaacggggac
atggagcccgaggccggcgccgcggcctcttcggctgcggaccctgccattccggaggag
gtgtggaatatcaagcaaatgattaagttgacacaggaacatatagaggccctattggac
aaatttggtggggagcataatccaccgtcaatatacctagaggcctatgaagaatacacc
agcaaactagatgctctccaacaaagagaacagcagttattggagtccctggggaatgga
actgacatttctgtttctagctctgcatcaatggacaccgttacatcttcttcctcttct
agcctttcagtgctgccttcatctctttcagtctttcaaaatcctacagatgtatcacgg
agcaaccccaagtcaccacaaaaacctattgttagagtcttcctgcccaacaaacagagg
acagtggtacctgcaaggtgtggagttacagtccgagacagtttaaagaaagcactgatg
atgagaggtcttatcccagagtgctgcgctgtttacagaattcaggatggagagaagaaa
ccaattggctgggacactgatatttcctggcttaccggggaggagttgcatgtagaagtg
ttggagaatgttccacttacaacacataactttgtacggaaaacttttttcaccttagca
ttttgtgacttttgtcgaaagctgcttttccagggtttccgctgtcagacatgtggttat
aaatttcaccaacgttgtagtacagaggttccactgatgtgtgttaattatgaccaactt
gatttgctgtttgtctccaagttctttgaacatcatccaataccacaggaggaggcctcc
ttagcagagactgcccttacatctggatcatccccttctgcacccccctcagactctatt
gggccccaaattctcaccagtccatctccttcaaaatccattccaattccacagcccttc
cgaccagcagatgaagatcatcgcaatcagtttgggcaacgggaccggtcctcgtcagct
ccaaatgtgcatataaacacaatagaacctgtcaatattgatgtaagtatatccagcatt
gctagaattaaaataccgtag |
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