KEGG   Castor canadensis (American beaver): 109682730
Entry
109682730         CDS       T04791                                 
Symbol
Hdac2
Name
(RefSeq) LOW QUALITY PROTEIN: histone deacetylase 2
  KO
K06067  histone deacetylase 1/2 [EC:3.5.1.98]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan03082  ATP-dependent chromatin remodeling
ccan03083  Polycomb repressive complex
ccan04110  Cell cycle
ccan04213  Longevity regulating pathway - multiple species
ccan04330  Notch signaling pathway
ccan04350  TGF-beta signaling pathway
ccan04613  Neutrophil extracellular trap formation
ccan04919  Thyroid hormone signaling pathway
ccan05016  Huntington disease
ccan05031  Amphetamine addiction
ccan05034  Alcoholism
ccan05165  Human papillomavirus infection
ccan05169  Epstein-Barr virus infection
ccan05200  Pathways in cancer
ccan05202  Transcriptional misregulation in cancer
ccan05203  Viral carcinogenesis
ccan05206  MicroRNAs in cancer
ccan05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    109682730 (Hdac2)
   03083 Polycomb repressive complex
    109682730 (Hdac2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    109682730 (Hdac2)
   04350 TGF-beta signaling pathway
    109682730 (Hdac2)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    109682730 (Hdac2)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    109682730 (Hdac2)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    109682730 (Hdac2)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    109682730 (Hdac2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109682730 (Hdac2)
   05202 Transcriptional misregulation in cancer
    109682730 (Hdac2)
   05206 MicroRNAs in cancer
    109682730 (Hdac2)
   05203 Viral carcinogenesis
    109682730 (Hdac2)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    109682730 (Hdac2)
  09172 Infectious disease: viral
   05169 Epstein-Barr virus infection
    109682730 (Hdac2)
   05165 Human papillomavirus infection
    109682730 (Hdac2)
  09164 Neurodegenerative disease
   05016 Huntington disease
    109682730 (Hdac2)
  09165 Substance dependence
   05031 Amphetamine addiction
    109682730 (Hdac2)
   05034 Alcoholism
    109682730 (Hdac2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:ccan03036]
    109682730 (Hdac2)
Enzymes [BR:ccan01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.98  histone deacetylase
     109682730 (Hdac2)
Chromosome and associated proteins [BR:ccan03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    Class I HDACs
     109682730 (Hdac2)
   HDAC complexes
    Sin3A-HDAC complex
     109682730 (Hdac2)
    BRAF-HDAC complex
     109682730 (Hdac2)
    REST complex
     109682730 (Hdac2)
    SHIP complex
     109682730 (Hdac2)
    MiDAC complex
     109682730 (Hdac2)
   Polycomb repressive complex (PRC) and associated proteins
    Noncanonical PRC1 (PRC1.6)
     109682730 (Hdac2)
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    109682730 (Hdac2)
  Chromatin remodeling factors
   NuRD complex
    109682730 (Hdac2)
SSDB
Motif
Pfam: Hist_deacetyl
Other DBs
NCBI-GeneID: 109682730
NCBI-ProteinID: XP_020013727
UniProt: A0A8B7U3G5
LinkDB
Position
Unknown
AA seq 494 aa
MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA
TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGXFEFCQLSTGGSVA
GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH
GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDXGSVYVFXDIGAGKGKYYAVNFPMRDGID
DESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNL
PLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQ
NTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAIHEDSGDEDGEDPDKRISIRASDKR
IACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKADVKEEDKSKDNSGEK
TDTKGAKSEQLSNP
NT seq 1485 nt   +upstreamnt  +downstreamnt
atggcgtacagtcaaggaggcggcaagaagaaagtctgctactattacgatggtgatatt
ggaaattattattatggacaaggtcatcccatgaaacctcatagaatccggatgactcat
aacttgctgttgaattatggtttatacagaaaaatggagatatatagaccccataaagcc
actgctgaagaaatgacaaaatatcacagtgatgagtatatcaaatttctacggtcaata
agaccagataacatgtctgagtatagtaagcagatgcagagatttaatgttggagaagat
tgtccagtgtttgatgggncttttgagttttgtcagctctccactggtggctcagttgct
ggggctgtaaagttaaaccggcagcaaaccgatatggctgttaactgggccggaggatta
catcatgccaagaaatcagaagcatcaggattctgttatgttaatgatattgtgcttgcc
atccttgaattactaaagtatcatcaaagggtcttatatattgatatagatatccatcat
ggtgatggtgttgaagaagctttttatacaacagatcgtgtaatgactgtttcattccac
aaatatggggaatactttcctggcacaggagactgaggctctgtttatgtgttttaggat
attggtgctggaaaaggcaaatactatgctgtcaattttccgatgagagacggtatagat
gatgagtcatacggacaaatatttaagcctataatctcaaaagtgatggagatgtatcag
cctagtgctgtggtgttacaatgtggtgctgactcattatctggcgataggcttggttgc
ttcaatctaacagtcaaagggcatgctaaatgtgtagaagttgtaaaaacttttaaccta
ccattgctgatgcttgggggaggtggatacacaatccgtaatgttgctcgatgttggaca
tatgaaactgcagttgcccttgattgtgaaatccccaatgaattgccatataatgactac
tttgaatattttggaccagacttcaaactgcatattagtccttcaaatatgacaaaccag
aacactccagaatatatggaaaagatcaaacagcgtttatttgaaaatttgcgcatgtta
cctcatgcacctggtgtccaaatgcaagctattccagaagatgctattcatgaagacagt
ggagatgaagatggagaagatccagacaagagaatttctattcgagcatcagacaaacgg
atagcttgtgatgaagaattctcagattctgaagatgaaggggaaggaggtcgtagaaat
gtggctgatcacaaaaaaggagcaaagaaagcaaggattgaagaagataagaaggagaca
gaggacaaaaaagcagatgttaaggaagaagataaatccaaggacaatagtggtgaaaaa
acagataccaaaggagccaaatcggaacaactcagcaacccttga

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