Castor canadensis (American beaver): 109685136 Help Entry 109685136         CDS       T04791                                  Symbol Pla2g4a Name (RefSeq) cytosolic phospholipase A2   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism ccan  Castor canadensis (American beaver) Pathway ccan00564   Glycerophospholipid metabolism ccan00565   Ether lipid metabolism ccan00590   Arachidonic acid metabolism ccan00591   Linoleic acid metabolism ccan00592   alpha-Linolenic acid metabolism ccan01100   Metabolic pathways ccan04010   MAPK signaling pathway ccan04014   Ras signaling pathway ccan04072   Phospholipase D signaling pathway ccan04217   Necroptosis ccan04270   Vascular smooth muscle contraction ccan04370   VEGF signaling pathway ccan04611   Platelet activation ccan04664   Fc epsilon RI signaling pathway ccan04666   Fc gamma R-mediated phagocytosis ccan04724   Glutamatergic synapse ccan04726   Serotonergic synapse ccan04730   Long-term depression ccan04750   Inflammatory mediator regulation of TRP channels ccan04912   GnRH signaling pathway ccan04913   Ovarian steroidogenesis ccan04921   Oxytocin signaling pathway ccan05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ccan00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     109685136 (Pla2g4a)    00565 Ether lipid metabolism     109685136 (Pla2g4a)    00590 Arachidonic acid metabolism     109685136 (Pla2g4a)    00591 Linoleic acid metabolism     109685136 (Pla2g4a)    00592 alpha-Linolenic acid metabolism     109685136 (Pla2g4a)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109685136 (Pla2g4a)    04014 Ras signaling pathway     109685136 (Pla2g4a)    04370 VEGF signaling pathway     109685136 (Pla2g4a)    04072 Phospholipase D signaling pathway     109685136 (Pla2g4a)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     109685136 (Pla2g4a)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109685136 (Pla2g4a)    04664 Fc epsilon RI signaling pathway     109685136 (Pla2g4a)    04666 Fc gamma R-mediated phagocytosis     109685136 (Pla2g4a)   09152 Endocrine system    04912 GnRH signaling pathway     109685136 (Pla2g4a)    04913 Ovarian steroidogenesis     109685136 (Pla2g4a)    04921 Oxytocin signaling pathway     109685136 (Pla2g4a)   09153 Circulatory system    04270 Vascular smooth muscle contraction     109685136 (Pla2g4a)   09156 Nervous system    04724 Glutamatergic synapse     109685136 (Pla2g4a)    04726 Serotonergic synapse     109685136 (Pla2g4a)    04730 Long-term depression     109685136 (Pla2g4a)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     109685136 (Pla2g4a)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     109685136 (Pla2g4a) Enzymes [BR:ccan01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      109685136 (Pla2g4a) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLA2_B C2 cPLA2_C2 Motif Other DBs NCBI-GeneID:  109685136 NCBI-ProteinID:  XP_020017437 UniProt:  A0A8B7UDU4 LinkDB All DBs Position Unknown AA seq 725 aa AA seqDB search MPPKVTKGAFGDMLDTPDPYVELFISTTPDGRKRTRHFNNDINPVWNETFEFILDPNQEN ILEITLMDANYVMDETLGTATFPVSSMKVGEKKEVPFIFNQVTEMILEMSLEVCSCPDLR FSMALCDQEKIFRQQRKENIKENMKKLLGPKSSEGLYSTREVPVVAILGSGGGFRAMVGF SGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEINEELMKNVSYNPLL LLTPQKIKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVTAARCP LPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENP LHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEELENITAKHIVSNDSSDSDDDSQDPK GTENEDAQREYQNDTQAGWVQRMLMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPLS PLRDFTTQESFEDDDELDAAVADPDEFEQIYEPLDVKSKKIHVVDSGLTFNLPYPLILRP QRGVDLIISFDFSARPSDTSPPFKELLLAEKWARMNKLPFPKIDPNVFDREGLKECYVFK PKNPDVENDCPTIIHFVLANINFRKYKAPGVPRETKEEKEIADFDIFDDPESPFSTFNFQ YPNQAFKRLHDLMYFNTLNNIDVIKDAIVESIEYRRQNPSRCSVSLSNVEARRFFNKEFL SKPTA NT seq 2178 nt NT seq  +upstreamnt  +downstreamnt atgccaccaaaagtaacaaagggggccttcggtgacatgcttgacactccagatccttat gtggaacttttcatctccacgacccccgacggcaggaagagaacaagacacttcaataat gacataaaccctgtgtggaatgagacctttgaattcattttggaccctaatcaggaaaat attttggagatcacgttaatggatgccaactatgtcatggatgaaactctagggacagca acatttcctgtgtcttctatgaaagtaggagagaagaaagaagttccatttattttcaac caagtcactgaaatgatcctggaaatgtcactggaagtttgctcatgcccagacctacga tttagtatggctctgtgtgatcaggagaaaattttcagacaacagagaaaagagaacata aaggaaaacatgaagaaacttttgggtccaaaaagtagtgaaggattatattctacacgt gaggtgcctgtggtggctatattgggctcaggtgggggtttccgagccatggtgggattt tctggtgtgatgaaggcgctatatgaatcaggaattttggattgtgctacctacgttgct ggtctttctggctccacatggtatatgtcaaccttgtactctcaccctgattttcctgag aaggggccagaagagattaatgaagaactaatgaaaaatgttagctacaaccccctttta cttctcacaccacaaaagattaaacgatatgttgagtcattgtggaagaagaaaagctcc ggccaacctgtcacctttactgatatctttggcatgttaataggagaaacactaatccac aatagaatgaacactaccttgagtagtttgaaggaaaaggtcactgctgcccgatgtcct ttacctcttttcacttgtttgcatgtcaaacctgatgtgtcagagctgatgtttgcagat tgggttgagtttagcccgtacgagataggcatggcgaaatatggcactttcatggctccc gacctgtttggaagcaaattttttatgggaacagttgtgaaaaaatatgaagaaaacccc ttgcattttttaatgggtgtgtggggaagtgccttttctatattgttcaacagagtcttg ggagtttctggttcacaaaataaaggttccacaatggaggaagaattagaaaatattaca gcaaagcatattgtgagtaatgatagctcggacagtgatgatgactcacaagaccctaaa ggcactgaaaacgaagatgcgcaaagggagtatcagaatgatactcaagcaggttgggtc cagcgtatgttgatggccttggtgagtgattcggctttattcaacaccagagaaggacgt gctggaaaggtgcacaacttcatgctgggcttgaatctcaacacatcctacccactgtct cctctgagagacttcaccacacaggagtccttcgaggatgacgatgaactggatgcagct gtggcagatcccgatgaatttgagcaaatatatgagccactggatgtcaaaagcaaaaag attcatgtagtggacagtgggcttacatttaacttgccatatcccttgatcctgagaccc cagaggggggttgatctcatcatctcttttgacttttctgcaaggccaagtgacaccagt cctccattcaaggaacttctactcgcagaaaaatgggctaggatgaacaagctccccttt ccaaagatcgatcctaatgtgtttgatcgggaagggctgaaggagtgctatgtctttaaa cccaagaatcctgatgtggagaatgattgtcctactatcatccactttgttctagccaac atcaacttcagaaagtacaaagctccaggtgttccaagagaaactaaagaagagaaagaa atagctgactttgacatttttgatgacccagaatcaccattttcaaccttcaactttcaa tatccaaatcaagcattcaaaaggctacatgaccttatgtacttcaatactctgaacaat atcgatgtgataaaagatgccatagttgaaagcattgaatacagaagacagaatccatct cgttgctctgtttccctcagtaatgttgaggcaagaagatttttcaacaaggagtttcta agtaaacccacagcatag

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