Castor canadensis (American beaver): 109686538 Help Entry 109686538         CDS       T04791                                  Name (RefSeq) son of sevenless homolog 2   KO K03099   son of sevenless Organism ccan  Castor canadensis (American beaver) Pathway ccan01521   EGFR tyrosine kinase inhibitor resistance ccan01522   Endocrine resistance ccan04010   MAPK signaling pathway ccan04012   ErbB signaling pathway ccan04014   Ras signaling pathway ccan04062   Chemokine signaling pathway ccan04068   FoxO signaling pathway ccan04072   Phospholipase D signaling pathway ccan04150   mTOR signaling pathway ccan04151   PI3K-Akt signaling pathway ccan04510   Focal adhesion ccan04540   Gap junction ccan04630   JAK-STAT signaling pathway ccan04650   Natural killer cell mediated cytotoxicity ccan04660   T cell receptor signaling pathway ccan04662   B cell receptor signaling pathway ccan04664   Fc epsilon RI signaling pathway ccan04714   Thermogenesis ccan04722   Neurotrophin signaling pathway ccan04810   Regulation of actin cytoskeleton ccan04910   Insulin signaling pathway ccan04912   GnRH signaling pathway ccan04915   Estrogen signaling pathway ccan04917   Prolactin signaling pathway ccan04926   Relaxin signaling pathway ccan04935   Growth hormone synthesis, secretion and action ccan05034   Alcoholism ccan05160   Hepatitis C ccan05161   Hepatitis B ccan05163   Human cytomegalovirus infection ccan05165   Human papillomavirus infection ccan05200   Pathways in cancer ccan05205   Proteoglycans in cancer ccan05206   MicroRNAs in cancer ccan05207   Chemical carcinogenesis - receptor activation ccan05208   Chemical carcinogenesis - reactive oxygen species ccan05210   Colorectal cancer ccan05211   Renal cell carcinoma ccan05213   Endometrial cancer ccan05214   Glioma ccan05215   Prostate cancer ccan05220   Chronic myeloid leukemia ccan05221   Acute myeloid leukemia ccan05223   Non-small cell lung cancer ccan05224   Breast cancer ccan05225   Hepatocellular carcinoma ccan05226   Gastric cancer ccan05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109686538    04012 ErbB signaling pathway     109686538    04014 Ras signaling pathway     109686538    04630 JAK-STAT signaling pathway     109686538    04068 FoxO signaling pathway     109686538    04072 Phospholipase D signaling pathway     109686538    04151 PI3K-Akt signaling pathway     109686538    04150 mTOR signaling pathway     109686538  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     109686538    04540 Gap junction     109686538   09142 Cell motility    04810 Regulation of actin cytoskeleton     109686538  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     109686538    04660 T cell receptor signaling pathway     109686538    04662 B cell receptor signaling pathway     109686538    04664 Fc epsilon RI signaling pathway     109686538    04062 Chemokine signaling pathway     109686538   09152 Endocrine system    04910 Insulin signaling pathway     109686538    04912 GnRH signaling pathway     109686538    04915 Estrogen signaling pathway     109686538    04917 Prolactin signaling pathway     109686538    04926 Relaxin signaling pathway     109686538    04935 Growth hormone synthesis, secretion and action     109686538   09156 Nervous system    04722 Neurotrophin signaling pathway     109686538   09159 Environmental adaptation    04714 Thermogenesis     109686538  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109686538    05206 MicroRNAs in cancer     109686538    05205 Proteoglycans in cancer     109686538    05207 Chemical carcinogenesis - receptor activation     109686538    05208 Chemical carcinogenesis - reactive oxygen species     109686538    05231 Choline metabolism in cancer     109686538   09162 Cancer: specific types    05210 Colorectal cancer     109686538    05225 Hepatocellular carcinoma     109686538    05226 Gastric cancer     109686538    05214 Glioma     109686538    05221 Acute myeloid leukemia     109686538    05220 Chronic myeloid leukemia     109686538    05211 Renal cell carcinoma     109686538    05215 Prostate cancer     109686538    05213 Endometrial cancer     109686538    05224 Breast cancer     109686538    05223 Non-small cell lung cancer     109686538   09172 Infectious disease: viral    05161 Hepatitis B     109686538    05160 Hepatitis C     109686538    05163 Human cytomegalovirus infection     109686538    05165 Human papillomavirus infection     109686538   09165 Substance dependence    05034 Alcoholism     109686538   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     109686538    01522 Endocrine resistance     109686538 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RasGEF RasGEF_N Motif Other DBs NCBI-GeneID:  109686538 NCBI-ProteinID:  XP_020019479 UniProt:  A0A8B7UKK6 LinkDB All DBs Position Unknown AA seq 687 aa AA seqDB search FEIPEPEPTEADKLAIEKGEQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERD LELLERLESFISSVRGKAMKKWVESIAKIIRRKKQAQANGISHNITFESPPPPIEWYISR PGQFETFELMTLHPIEIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRH TTNLTLWFEKCIVEAENFEERVAILSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLD HTFEALQERKRRILDEAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDF LKKKGKDLINFSKRRKVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSLSEKEFTD YLFNKSLEIEPRSCKQPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPYK ISFSRIAETELESTVSAPTSPNTPSTPPVSASSDLSVFLDGDLSSSCGSNSIFAPVLLPH SKSFFSSCGSLNKLSEEPLIPPPLPPRKKFDHDASNSKGTMKSDDDPPAIPPRQPPPPKV KPRVPVPTGAFDGPLHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRD PEWFRDVSTCPNSPSTPPSTPSPRIPRRCSVLSSTHNPLAHPAAPPVPPRQNSSPHLPKL PPKTYKRELSHPPLYRLPLLENAETPQ NT seq 2065 nt NT seq  +upstreamnt  +downstreamnt atttgaaattccagagccagaacctactgaagcagacaaattagcaatagagaaaggcga gcagccaatcagtgcagaccttaaaagatttcgcaaggaatacgtccaaccagtacaact tagggtcttaaatgtgtttcgacactgggttgaacaccatttttatgactttgaaagaga tttggaattgcttgaaagactagaatctttcatttcaagtgtaagagggaaagctatgaa gaaatgggtagagtcgattgctaagatcatcaggaggaagaagcaagcccaggcaaatgg aataagccataatattacctttgaaagtccacctccaccaattgaatggtacatcagtag accaggacagtttgaaacatttgagcttatgacacttcatccaatagaaattgcacgtca gctgacacttttggaatctgatctctacaggaaagtccaaccttctgaacttgtagggag tgtgtggaccaaagaagataaagaaataaattctccaaatttattaaaaatgattcgcca tacaacaaatctcaccctgtggtttgaaaaatgcattgtggaagcagaaaattttgaaga acgggtggcaatactaagtagaattatagaaattctgcaggtttttcaagatttgaataa tttcaacggcgtactggagatagtcagcgcagtaaattcagtgtcagtgtacagactaga ccatacctttgaggcattacaggaaagaaaaaggagaattttggatgaagctgtggaatt aagtcaggatcactttaaaaaatacctagtaaaacttaaatcaatcaatccaccttgtgt gcctttttttggaatatatttaacaaatattctgaagactgaagaagggaataatgattt tctaaaaaagaaagggaaagatttaatcaatttcagtaagagaaggaaagtagctgaaat tactggagaaattcagcagtatcagaatcagccttactgtttacggatagaaccagaaat gaggagattctttgaaaaccttaaccccatgggaagtttatctgaaaaagagtttacaga ctatttgttcaataaatcactagaaattgaaccccgaagctgcaaacagccacctcgatt tcctaggaaatcaactttctccttaaaatctcctggaataaggcctaatacaggccgaca tggctctacctcaggtactctacgaggtcatccaacaccattagaaagagaaccctataa aataagctttagtcggattgctgaaactgagcttgaatcaacagtgtcagcaccaacatc tccaaatacaccatctactccaccagtatctgcttcttcagaccttagtgtgtttttaga tggggatctcagtagttcctgtggcagcaatagcatctttgctccagtgctcttgccaca ttcaaagtctttcttcagttcatgtggtagtttaaataaactaagtgaagagccactgat tcctccccctcttcctcctcgaaaaaagtttgatcatgatgcttcaaattccaagggaac tatgaaatcagatgatgaccctcctgcaattccaccaagacagcctccacctccaaaggt aaaacccagagttcctgttcctactggtgcgtttgatgggcctctgcatagtccacctcc accaccaccaagagatcctcttcctgatacccctccaccagttccactacggcctccaga acactttataaactgtccatttaatcttcaaccacctccactgggacatcttcacagaga tccagagtggttcagagacgttagtacgtgtccaaattctccaagcacacctcctagcac accctctccaagaataccacgtcgatgctctgtgctcagttctactcacaaccctcttgc tcatcctgcagctccccctgttccaccaaggcagaattcaagccctcacctaccaaaact gccaccaaagacttacaaacgggagctttcacaccccccattatatagactgcctttgct agaaaatgcagaaacgcctcaatga

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