Castor canadensis (American beaver): 109686786
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Entry
109686786 CDS
T04791
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan00790
Folate biosynthesis
ccan01100
Metabolic pathways
ccan01240
Biosynthesis of cofactors
ccan01523
Antifolate resistance
ccan04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
109686786 (Fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
109686786 (Fpgs)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
109686786 (Fpgs)
Enzymes [BR:
ccan01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
109686786 (Fpgs)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
109686786
NCBI-ProteinID:
XP_020019864
UniProt:
A0A8B7ULS5
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Position
Unknown
AA seq
587 aa
AA seq
DB search
MWWAQRHLRAALSLAAVSARSATTEVAARRGLSAWPAPQEPGMEYQDAVRMLNTLQTNAS
YLEQVKRQRSDPQSQLEAMERYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTEHILRN
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWRLYHRLEETKDSSCVSMPAYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTMEKIA
WQKGGIFKHGIPAFTVLQPEGPLAVLRDRAQQISCPLYLCPPLEALEEGAPPLILGLEGE
HQRSNAALALQLAHCWLQHHNNQDIQELKMSRPSVRWQLPLAPVFQPTSHMRHGLRDTEW
PGRTQVLLRGPLTWYLDGAHTTSSIQACVRWYRQALQRRERPSGGPEVRVLLFNSTGDRD
PAALLKLLQPCRFDYAVFCPNLTEVSSTGSADQQNFTVTLDQVLLRCLQHQQHWNCLGEE
QDSSDLWSSPNLEPSGPTSLLLAPHSPHPCSASSLVFSCISHALQWISQGRDPIFQPPSP
PRGLLAHPVANSGATVLREAAAIQVLVTGSLHLVGGVLKLLEPSMSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtggtgggcgcagcgccatctgcgcgcagctctgtctctagcagccgtttctgctcgt
agtgcaacaaccgaggtcgcggcgcggcgggggttgagcgcgtggccggcgccgcaggag
cccggcatggagtatcaggatgccgtgcggatgctcaacaccctgcagaccaacgccagc
tacctggagcaggtgaagcgccaacggagtgacccccagtcacagttggaagccatggaa
cggtaccttgcacggagtgggctgcaggtggaggacctggaccggctgaacatcatccat
gtcactgggaccaaggggaagggctccacttgtgcctttactgagcatatcttgcggaat
tatggcctgaagacgggattctttagctctccccacctggtgcaggtgcgtgagcggatt
cgcatcaatgggcaacccatcagccccgagctcttcaccaagcacttctggcgcctctac
caccgactagaggagaccaaggacagcagctgtgtctccatgcctgcctacttccgcttc
cttacactcatggccttccatgtcttcctccaagaaaaggtcgacctggcagtggtagaa
gtgggcatcggcggggcttatgactgtacaaacatcatcaggaagcctgtggtgtgtgga
gtatcttctcttggcattgatcacaccagtcttctgggagacacaatggagaagatagcc
tggcagaaagggggcatctttaagcatggcatccctgccttcaccgtgctccagccagaa
ggtcccctggccgtgctgagggatcgagcccagcagatctcatgtcctctctacctgtgc
ccaccactggaagctctggaggaaggggcgccaccactgatcctgggcctggagggagag
caccagagatccaatgcagccttggccttgcagctggcccactgctggctccagcaccac
aacaaccaggacatccaggagctgaagatgtccaggccaagcgtccggtggcagctgccc
ctggcacctgtgttccagcccacatcccatatgcggcatgggcttcgagacacagagtgg
cctggccggacgcaggtgttactgcgtgggcccctcacttggtacttggatggcgcacat
accaccagcagcatccaggcctgtgtgcgctggtaccgccaggcgctgcagcgcagggag
aggccgagtggagggcccgaggtgcgtgtcttgctcttcaactccactggagacagagac
cctgccgccctgctgaagctactgcagccttgccggtttgactatgctgtcttctgtccc
aacctgacagaggtgtcatccacaggcagcgcagaccagcagaacttcactgtgacattg
gaccaggtgcttctccgttgcctccaacaccagcagcactggaactgcctgggtgaggag
caagatagctccgatctctggagttccccaaacctggagcctagtggacccacatccttg
ctgttggcaccccactcaccccatccctgcagtgccagctcccttgtcttcagctgcatc
tcccatgccttacagtggatcagccaaggccgggaccccatctttcagccacccagtccc
ccaaggggcctccttgcccaccccgtggccaacagtggggccactgttctccgtgaggct
gcagcaatccaagtgctggtcacgggcagcctgcatctggtgggcggtgtcctgaagctg
cttgagccctccatgtcccagtaa
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