Castor canadensis (American beaver): 109688078 Help Entry 109688078         CDS       T04791                                  Symbol Syk Name (RefSeq) tyrosine-protein kinase SYK   KO K05855   spleen tyrosine kinase [EC:2.7.10.2] Organism ccan  Castor canadensis (American beaver) Pathway ccan04064   NF-kappa B signaling pathway ccan04072   Phospholipase D signaling pathway ccan04151   PI3K-Akt signaling pathway ccan04380   Osteoclast differentiation ccan04611   Platelet activation ccan04613   Neutrophil extracellular trap formation ccan04625   C-type lectin receptor signaling pathway ccan04650   Natural killer cell mediated cytotoxicity ccan04662   B cell receptor signaling pathway ccan04664   Fc epsilon RI signaling pathway ccan04666   Fc gamma R-mediated phagocytosis ccan05152   Tuberculosis ccan05167   Kaposi sarcoma-associated herpesvirus infection ccan05168   Herpes simplex virus 1 infection ccan05169   Epstein-Barr virus infection ccan05171   Coronavirus disease - COVID-19 ccan05203   Viral carcinogenesis Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     109688078 (Syk)    04072 Phospholipase D signaling pathway     109688078 (Syk)    04151 PI3K-Akt signaling pathway     109688078 (Syk)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     109688078 (Syk)    04613 Neutrophil extracellular trap formation     109688078 (Syk)    04650 Natural killer cell mediated cytotoxicity     109688078 (Syk)    04662 B cell receptor signaling pathway     109688078 (Syk)    04664 Fc epsilon RI signaling pathway     109688078 (Syk)    04666 Fc gamma R-mediated phagocytosis     109688078 (Syk)   09158 Development and regeneration    04380 Osteoclast differentiation     109688078 (Syk)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     109688078 (Syk)   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     109688078 (Syk)    05167 Kaposi sarcoma-associated herpesvirus infection     109688078 (Syk)    05169 Epstein-Barr virus infection     109688078 (Syk)   09171 Infectious disease: bacterial    05152 Tuberculosis     109688078 (Syk)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ccan01001]     109688078 (Syk) Enzymes [BR:ccan01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      109688078 (Syk) Protein kinases [BR:ccan01001]  Non-receptor tyrosine kinases   SYK family    109688078 (Syk) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 Kdo DUF7145 DUF7063 ABC1 SH2_1 RIO1 Motif Other DBs NCBI-GeneID:  109688078 NCBI-ProteinID:  XP_020021918 UniProt:  A0A250YKH5 LinkDB All DBs Position Unknown AA seq 632 aa AA seqDB search MAGNVADSANHLPFFFGNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHSRKA HHYTIEREINGTYAIPGGRTHSSPADLCHYHSQESDGLVCLLIKPFNRPPGVQPKTGPFE DLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHETMPWFHGNISRDESEQI VLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLV EHYSYKPDGLLRVLTVPCQKIGSQMGHPQSSSPSSGGWSPGGIISRIKSYSFARPGHKKT PPSQGNRQDRPESTASFNPYEPDRGPWPAERGPQREALPMDTEVYESPYADPEEIRPKEV YLDRNLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPTLKDELLAEANV MQQLDNPYIVRMIGICDAESWMLVMEMAELGSLNKYLQQNRHIKDKNIIELVHQVSMGMK YLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPEC INYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPPGCPREMYE LMNLCWTYEVENRPGFVAVELRLRNYYYDVVN NT seq 1899 nt NT seq  +upstreamnt  +downstreamnt atggcaggcaacgtggcggacagcgccaaccacctgcccttcttttttggcaacatcacc cgagaggaggcagaagactacctggtccaggggggcatgaccgatggactctacctgtta cgccagagtcgtaattacctgggtggctttgccctgtcagtggcccacagcaggaaggca caccactacaccatcgagagggagatcaatggcacctatgccatccctggtggcaggacc cacagcagccctgctgacctctgccactaccactcccaggagtccgacggcctggtctgc ctcctcataaagcccttcaaccggccccctggggtgcagcccaagactgggccatttgag gacctgaaggaaaacctcatcagggagtacgtgaagcagacgtggaacctgcagggccag gctttggaacaagccatcattagccagaagccccagctggagaagttgatcgccaccact gcccatgaaacaatgccatggttccatggcaatatctctcgggatgaatcagagcagatt gtcctgataggatcaaagacaaatggaaagtttctgatcagggccagagacaacaatggc tcctatgcactgtgcctgctgcacgaagggaaggtgctgcactaccgcatcgacaaggac aagacagggaagctctccatccctgagggaaagaagtttgacacactctggcagctggtg gaacattattcttataaacctgatggcctgttaagagttcttactgtgccatgtcaaaag attggctcacagatgggtcatccgcaaagttcaagtccctcctctgggggttggtctcca ggtggcataatctcaaggatcaaatcctactcctttgcaaggcctggccacaaaaagacc cccccgtcccaagggaaccggcaagaccggccagagagtactgcatccttcaatccctat gagccagaccgaggaccctggcctgcagagagaggccctcagagagaagctctgcccatg gatacagaggtgtatgaaagcccctatgctgaccctgaggaaatcaggcccaaagaggtc tacctggaccgaaacctgctgaccctggaggacaaagaactgggctctggtaactttgga accgtgaaaaagggctattaccaaatgaaaaaagttgtgaaaacggtggctgtgaaaata ctgaaaaacgaggccaacgaccccactctgaaagacgagctgctggcggaggcgaacgtc atgcagcagctggacaacccctacatcgtgcgcatgattgggatttgcgacgccgagtcc tggatgctggtgatggagatggcagaactcggttctctcaacaagtatttgcagcagaac aggcacatcaaggataagaacatcatagagctggttcatcaggtttccatgggaatgaaa tacttggaggagtgcaatttcgtgcacagagatctggctgcaagaaatgtattgctggtc actcagcattatgccaagatcagtgattttggtctttccaaagcgcttcgtgctgacgaa aactactataaggcgcagacccacgggaagtggccggtgaagtggtatgcccccgaatgc atcaactactacaaattctccagcaagagtgatgtctggagcttcggagtgctcatgtgg gaagcattttcctatgggcagaagccgtatcgagggatgaaaggaagtgaggttactgcc atgctggagaagggagagcggatggggtgtccaccagggtgcccaagagaaatgtatgag ctgatgaacctgtgctggacctatgaggtggagaacaggcctggatttgtagcggtggag ctgcggctgcgcaattattactacgacgtggtgaactag

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