Castor canadensis (American beaver): 109689929
Help
Entry
109689929 CDS
T04791
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan00310
Lysine degradation
ccan01100
Metabolic pathways
ccan05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
109689929 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
109689929 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ccan03036
]
109689929 (Dot1l)
Enzymes [BR:
ccan01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
109689929 (Dot1l)
Chromosome and associated proteins [BR:
ccan03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
109689929 (Dot1l)
HMT complexes
Dot1-containing complex
109689929 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
DUF1924
VPS13_M
Motif
Other DBs
NCBI-GeneID:
109689929
NCBI-ProteinID:
XP_020024602
UniProt:
A0A8B7V031
LinkDB
All DBs
Position
Unknown
AA seq
1534 aa
AA seq
DB search
LERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNF
RINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREE
QEAARRRQQRENKSNATTPTKVPESKVTGPAETPMDSGAEEEKAAVTTIKKPSPSKTRKK
KLNKKGRKMAGRKRGRPKKMSTANPERKPKKNQTALDLLHAQTSSQTASPSPQDAYRSPH
SPCYQLPPSAQWHSPSPLLVASTPPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQ
EKERNAQLLGTAQQLFGHCQAQKEEIQRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQ
LREQSEQLERDNRELRSQSLQLLRARCEELKLDWATLSLENLRKEKQALRSQISEKQRHC
LELQISIVELEKSQRQQELLQLKSCVPPDDTLSMHLRGKGALGRELEADAGRLHLELDCA
KFSLPHFNSMSPELSMNGHAAGYELCSALSRPSSKQNTPQYLASPLDQEVVPCTPNHSSR
PRLEKLSGLALPDYTRLSPAKIVLRRHLGQDHAAAGKAATSEPHPRAEHAKENSLPYQSP
GLSNSMKLSPQDPQPPSPGALPIVGEKSSEKQGVKERTYSSQGETITSLPISIPLSTVQP
NKLPVSIPLASVVLPSRAERVVSPAWLRRSTPSPVPQPRDSSSMLEKQIGANTHSAGGNA
TGSRSLALAPTGFSYAGSVAISGALASSPAPLASGAESAAFDESSSSGSLFTTMGSRSTT
PQHPPLLPQPRNSGPASPGPQLSASPRLSGTTQGLLPDAGKGDLPSDSGFSDPESEAKRR
IVFTISAGAGNTKQSPSTKHSPLMAGARGDCGQSHGQDSRKRGRRKRTSTGTPSLSTSVS
PKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPLEITAISSPENSLKSSPVPYHDHDQPP
VLKKERPLSQSNGAHYSPLTSDEEPGSEDEPSSTRIERKIATISLESKSPPKTLENGGSL
VGRKPTPASEPVNSSKWKSTFSPISDIGLAKSSDSPLQASSALSQNSLFSFRPALEEPSV
AEAKLTTHPRKSFSSSLLGADGLSPGANPPNGLAFSGGLAADLSLHGFNDGASLSHKGPE
AASLSAPLNFPSQRGKESASEANPFLSKRQLEGLGGLKGESSMGKEPGEPGLPLCGPVDK
ATLPHSRVGKGRDRELDFKNGHNLFISAAAVPHGSLLGGPGLATVASSTGSGAPAVQTHR
PFLGTFTPGPQFTLSPMSLQANLGSVAGSSVLQSLFSSVPAAAGLVHVSSAATRLTNSHA
MGSFSSGVAGGTVGGVFSHAVPSASAHPFGASVGSGAVCSSATLGLSPLQAVASTSASSF
QAVASVETRPPPPPPPPLLPPQHLGQPPEGPPILHAPPPPNVALPPPPPTLLASNSEPVL
LQNLASLPANKAFLPSSSAASLQPNAALSVKLTSLPHKVSRPSFTVHHQPLPRLALAQAA
PAVPQASSAGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
4605 nt
NT seq
+upstream
nt +downstream
nt
ctggaacgaggtgatttcctctcagaagagtggagagaacggattgccaacacgagtgtt
atatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaaggagcgattt
gcaaacatgaaggaaggtggcagaatcgtgtcctcaaaaccctttgcacctctgaacttc
agaataaacagcagaaacttgagtgatattggcaccattatgcgtgtggtggagctgtca
cccctgaaaggctccgtatcatggacaggaaagccagtctcctactacttgcacaccatt
gaccgtaccatacttgaaaactatttttctagtctgaaaaatccaaaactcagggaagaa
caggaggcagctcggcgccggcagcagcgagagaacaagagtaatgcaaccacccctacc
aaggtccctgagagcaaggtgactggccctgctgagacccccatggattctggtgctgag
gaagaaaaagcagcggtgaccaccatcaaaaagccatctccctccaaaacccggaagaag
aagttgaacaaaaaagggaggaagatggctggcaggaagcgtgggcggcccaagaaaatg
agcactgcaaaccctgagcgtaagcccaagaagaaccaaactgcactggatctcttgcat
gcccagacttcatcccagacagcgtccccctcaccccaagatgcatacaggtcacctcac
agcccatgctaccagctacctccaagtgcacagtggcactccccctccccactgctggtg
gcatccaccccacctgcactacagaagctgctagagtccttcaagatccaatacctgcag
ttcctggcctacacgaagaccccacagtataaggccaacctgcagcagctattggaccag
gagaaggagaggaacgcgcagttgctgggcacagcacagcagctctttggtcactgccag
gcccagaaggaagagatccagagactcttccagcagaaactggatgagcttggggtaaag
gcgctgacctacaatgacctgatccaggcccagaaggagatctctgctcacaaccagcag
ctgcgggaacagtcggagcagttggaaagggacaaccgtgagctccgcagccagagtctg
cagctgctcagagcccggtgcgaggagctgaagctggactgggcaacactgtccctggag
aacctgcggaaggagaagcaggcccttaggagccagatttcagagaagcagcgacactgc
ctggagctacagatcagcattgtggagctggagaaaagtcagcggcagcaggagcttctg
cagctaaagtcctgcgtgccacccgatgacacactatccatgcacctgcgtggaaagggt
gccctgggccgtgagctggaggccgatgctggcaggctgcacctagagctggactgcgct
aagttctctctgcctcatttcaacagtatgagcccagagctctccatgaatggccatgct
gctggctatgagctctgcagtgcactgagccggccctcatcaaagcagaacactccccag
tacttggcctcccccttggaccaggaggttgtgccctgcacccccaaccatagcagccgg
ccacggctggagaagctgtctggcctggccttgccggactatacccggctttcacctgct
aagattgtgctgaggaggcacctgggccaggaccatgctgcagctggcaaggcagccacc
agtgagccacacccacgagctgagcatgccaaggagaatagccttccttaccagagccca
ggcttgtcaaacagcatgaagctgagcccacaggacccacaacctccttcccctggggcc
ttgcccatagtaggagaaaagagcagtgagaagcagggtgtgaaggaacgtacctacagc
agccagggggagaccatcaccagcctgcctatcagcatcccgctcagcacagtgcagcca
aacaagctccctgtcagcatccccctggccagcgtggtgctccccagccgtgctgagagg
gtggtgagcccggcctggctacggaggagcaccccaagtcctgtgccacagccccgagac
tcatcatccatgcttgagaagcagatcggtgctaacacccacagtgccgggggcaatgct
acagggagcaggagccttgccctggcacccacaggcttctcctacgcaggctcagtggcc
atcagtggggccctggccagtagcccagcaccactggcctctggagcagagtcagctgcc
tttgacgagtcctccagttcggggagcctttttaccacaatggggtcccgcagcacgacg
cctcagcacccccctctgctgccacagccccgaaactccggccctgcctctcctggcccc
cagctctctgcaagtccccgactcagtgggaccactcagggcttgctgcctgatgctgga
aagggagacctgccttctgattctggcttctcagaccctgagagcgaggccaagaggaga
attgtgttcaccatctcagccggcgctggcaacaccaagcagtcaccttccaccaagcac
agccccctgatggcaggtgcccgtggggactgtgggcagagccatgggcaggatagccgg
aagcgtggcagaaggaagcgtacatcaaccggaactcccagcctaagcacaagcgtttcc
cccaagcgcagggctcttcccacagtcgctggcctcttcacacagtcctcaggatccccc
ctcaacctcaactccatggtcagcaacattaaccaacccttggagattacagctatctcg
tcccctgagaactctctgaagagctcccctgttccttaccatgaccatgaccagcccccc
gtgctcaagaaggagaggcccttgagccagtccaatggggctcactactccccgctgacc
tcagatgaggagccaggctctgaggatgagcccagcagcacccggattgagagaaaaatt
gcaacaatctctttagaaagcaagtctcccccaaaaaccttggaaaatggtggcagcttg
gtgggaaggaagccaacacccgcgagtgagcccgtgaacagcagcaagtggaaatctacc
ttctcacccatctccgacattggcctggccaagtcctcagacagcccactgcaggccagc
tctgccctgagccaaaactccttattctcattccgaccagccctggaggagccctcagtg
gctgaggccaaacttactacccatccaaggaaaagcttttccagctccctattgggagct
gatggactcagcccgggtgccaacccccccaatggcctggccttcagcgggggcctggct
gctgacctcagtttacatggcttcaacgatggtgcttccctttcccataagggtcctgag
gcagccagcctgagtgctccactgaactttccctcacagcggggcaaggagagtgcctca
gaggccaaccccttcctcagcaagcgacagctggagggcctgggtggcctgaagggtgag
agcagtatgggcaaggaaccaggcgagccaggcctgcccctgtgtgggcccgtggacaag
gccacccttcctcacagcagggttggcaagggccgagaccgtgaacttgacttcaagaat
ggccacaacctcttcatctctgctgcagcagtgcctcatggcagccttctcggtggccct
ggccttgccacagtggcatcctctacaggcagtggagcccctgctgtccagacacaccgc
cccttcctgggcaccttcacacctgggccacagttcaccctgagtcctatgtccctgcag
gccaaccttggctcggtggctggctcgtccgtgctgcagtccttgttcagttctgtgcca
gcagctgcaggcctggtacatgtctcatctgctgcaaccagactgaccaactcacatgcc
atgggcagcttctcctccggggtggctggcggaaccgttggaggtgtctttagccatgcg
gtgccctccgcctctgctcatccatttggagccagtgtcggcagcggggctgtgtgtagc
agcgccacgctaggcctaagcccactgcaggcggtggccagcacctcggcctcttccttt
caggccgtggcctcagtggagactcggccaccccctccacctccacctcctctacttcct
cctcagcacctgggccagccccctgaggggccccccattctccacgccccccctccacct
aatgttgccttgcctcctcccccacccacgctgctggcctctaactccgaacctgtgctc
ctacagaacctcgcgtccctcccagctaacaaagctttcttaccctcctcctctgctgcc
tctctgcagcctaacgccgctctgtctgtcaagctcacctcccttccacacaaggtctcc
cgcccctccttcacggtgcaccaccagcccctgccccggctggccctggcgcaggccgcg
cccgccgtccctcaggccagctctgcagggccatctgctgtatgggtttctcttggcatg
ccgcctccttatgccgcgcacctttcaggggttaagcctcgataa
DBGET
integrated database retrieval system
