Castor canadensis (American beaver): 109690162 Help Entry 109690162         CDS       T04791                                  Symbol Tsc2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism ccan  Castor canadensis (American beaver) Pathway ccan04072   Phospholipase D signaling pathway ccan04115   p53 signaling pathway ccan04140   Autophagy - animal ccan04150   mTOR signaling pathway ccan04151   PI3K-Akt signaling pathway ccan04152   AMPK signaling pathway ccan04211   Longevity regulating pathway ccan04218   Cellular senescence ccan04714   Thermogenesis ccan04910   Insulin signaling pathway ccan04919   Thyroid hormone signaling pathway ccan05163   Human cytomegalovirus infection ccan05165   Human papillomavirus infection ccan05168   Herpes simplex virus 1 infection ccan05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     109690162 (Tsc2)    04151 PI3K-Akt signaling pathway     109690162 (Tsc2)    04152 AMPK signaling pathway     109690162 (Tsc2)    04150 mTOR signaling pathway     109690162 (Tsc2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     109690162 (Tsc2)   09143 Cell growth and death    04115 p53 signaling pathway     109690162 (Tsc2)    04218 Cellular senescence     109690162 (Tsc2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     109690162 (Tsc2)    04919 Thyroid hormone signaling pathway     109690162 (Tsc2)   09149 Aging    04211 Longevity regulating pathway     109690162 (Tsc2)   09159 Environmental adaptation    04714 Thermogenesis     109690162 (Tsc2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     109690162 (Tsc2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     109690162 (Tsc2)    05163 Human cytomegalovirus infection     109690162 (Tsc2)    05165 Human papillomavirus infection     109690162 (Tsc2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:ccan01009]     109690162 (Tsc2) Protein phosphatases and associated proteins [BR:ccan01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      109690162 (Tsc2) SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP DUF6344 Cnd1 Motif Other DBs NCBI-GeneID:  109690162 NCBI-ProteinID:  XP_020024947 LinkDB All DBs Position Unknown AA seq 1946 aa AA seqDB search MSALVRPRKCWLRFRRRLAGGRGVCAFLRGWWLGERRERAGGGLLWSCGALPTMAKPASK DSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSVECGLNNRIRVIGQICEV AKTKKFEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGVLRALFFKVI KDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDVGLSSEFLLVLVNLVKFN SCYLDEYIASMVHMICLLCIRTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTI NVKELCEPCWKLMRNLLGTHLGHSAIYNMCRLMEDRSYMEDAPLLRGAVFFVGMALWGAH RLSSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDILLSIIER LLQQLQSLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVESYADQRPESSLLNLI SYRAQSIHPAKDGWIQNLQLLMERFFRSESRSAVRIKVLDVLSFVLLINRQFYEEELINS VVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARTLSPPPELEE RDVSAYSASLEDVRTAVLGLLVILQTKLYTLPASHATRVYETLISHIQLHYKHSYSLPIA SSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCLCDCVEPERGSDKKASGPLSPPT GPTSPVPVGPAVRLGHLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYKVLIFTSR CSVDQLSSALCAMLSGPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQRE MVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMAIPLLEFL STLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKD FVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARAPKQGLSNSPPVKEFK ESCAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHLELTETCL DMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGE LQGSPESSSEPGVHVRRTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDIQTP HITGGPTSPGPQQTIPATKPEKASAGTQVPAPEKTNLAAYVPLLTQGWAEILVRRPTGNT SWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAGTSKPPPL PRSNTGTVLPGHTLALLCGYRWRLAAEDVCVWEVGKHCPPLPLGEPRALCAGPGRRWPAP LSSPGSGLCLSSARPVQSLLLTRPLAWLPCSGLSVLPVPVQLPRTAAQERFLDSAVVLEE GNQGRAHMPTGPPELEDFEAVLGADRSCPYPVTYSRSSSASSQEEKSSHTEELAAGGIPI ERAISSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEAKARSQ SGILDGEGAAWSVPGEENQGPAPPEGSLPSSSPRSPSGLRPRGYTISDSAPSRRGQRVER DTFKSRAAASSAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPS YDTHKIAVLYVGEGQSGSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDV CGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFTL GTIKGQFNFVHVIITPLDYECNLLTLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHA NMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRIREEAHYSSPSLPLMHPSAHAKAPAP TEPTTTYETGQRKRLISSVDDFTEFV NT seq 5841 nt NT seq  +upstreamnt  +downstreamnt atgtccgcgctggtccgcccccggaagtgctggttgcgcttccggcggaggctcgctggg ggccgaggggtgtgcgcctttctccgcggctggtggctgggtgagcggcgggagcgcgcg ggaggaggcctcctgtggtcctgtggcgccctgcccaccatggccaagccagcaagcaaa gattcaggcttgaaagagaagttcaagattctgctgggactgggaacaccaaggccaaat cccaggtctgcagaaggcaagcagacagagtttatcatcacagcggaaatcttgagagaa ctgagtgttgaatgtggtctcaacaatcgcatccgggtgatagggcagatctgtgaagtg gcaaaaactaagaaatttgaagagcatgcagtggaagcactctggaaggccgtctcagac ctgctgcagcccgagcggccaccagaggcccgacatgcagtactggccctgctgaaagcc atcgtgcaagggcagggtgaccgcttaggggtcctcagagctctcttctttaaggtcatc aaggattacccctccaatgaagacctccatgaaaggctggaagttttcaaggcccttact gataatgggagacatatcacctacttggaagaagaactggcggagtttgtcttgcaatgg atggatgtcggcttgtcctcggaattccttctggtgcttgtgaacttggtcaaattcaac agctgttatcttgatgaatacatcgcatcaatggtgcacatgatctgtctgctgtgcatc cgaaccgtgtcctctgtggacatagaggtctccttgcaggtgctggatgccgtggtctgc tacaactgtctgcctgccgagagcctccctttgttcattgtcaccctctgccgcaccatc aatgtcaaggagctctgcgagccctgctggaagctcatgcgtaacctcctgggcacccac ttgggtcacagtgcaatctacaacatgtgccgcctaatggaagacagatcctacatggaa gatgccccgctgctgagaggagccgtgttctttgtgggcatggctctctggggagcccac cgactcagttctctcaagaattccccaacatctgtgttgccatctttttatgaggccatg acctgtcccaatgaggtggtgtcctatgagatcgtgctgtccataaccagactcattaag aagtataggaaggagctccaagctgtgacatgggacattctgctgagcatcattgaacgg ctgcttcagcagctccagagcctggacagcccggagctcaggaccatcgtccatgaccta ctgacaacggtggaggagctatgtgaccagaacgagttccatggctcacaggagagatac tttgaactagtggagagctatgcagaccagaggcctgagtcttccctcttaaatctaata tcctacagagctcagtccattcatccggccaaggacggctggatccagaacttgcagctg ctgatggagaggttcttcaggagcgagtcccgcagtgctgtgcgcatcaaggtactggat gtgctgtccttcgtgctgctcatcaacaggcagttctatgaggaggagctgattaactcg gtggtcatctcacagctctcccacatccctgaggataaagaccaccaagtccgaaagcta gccactcagttgttggtggacctggcagaaggctgccacacccatcacttcaacagtctc ctggacattattgaaaaagtgatggctcgcaccctgtctccaccccctgaactggaggaa agggatgtgtctgcttactcagcctctctggaggatgtgaggactgcagttctggggctc ctggttatccttcagaccaagctgtacactctgcctgccagccatgccacacgtgtgtac gagacactcatcagtcatatccagcttcactacaagcacagctactccctgcccattgct agcagcatccgactgcaggccttcgacttcctgctgctgctgcgagctgattcactgcac cgcctgggtctgcccaacaaagatggggtcgtgaggttcagcccctactgcctttgtgac tgcgtggagccagagaggggctctgataagaaggccagtggccccctttcacctcccact gggcctactagccctgtacctgtgggccctgctgtgcgtcttggccacctgccatactcc ctgctcttccgtgtcctactgcaatgtctgaagcaggagaccgactggaaggtgctgaaa ctggtcctgagcaagctgcctgagtcactgcgctacaaggtcctcatcttcacctcccgt tgcagtgtcgaccagctgtcttctgccctctgtgccatgctttcaggcccaaagaccctt gagcggctccgaggtaccccagaaggcttttccagaactgacctgcatttagctgtggtt ccagtgctaacggcgttaatctcttaccacaactatctagacaaaaccaaacagcgtgag atggtttactgcctggaacaaggcctcatctaccgctgtgccagccagtgtgtggtggcc ctggccatctgcagcgtggagatgccggacatcatcatcaaggcactgcccgtactggtg gtgaagctcacgcacatctctgccacggccagcatggccatcccgctcctggagttcctg tccactttggccaggttgccccacctctacagaaacttcgccgcagagcagtatgcaagt gtgtttgccatatccctgccgtacaccaatccctccaagttcaatcagtacatcgtgtgc ctggcccatcacgtcatagccatgtggttcatcaggtgccgcctgcccttccggaaggat tttgtcccttacatcactaagggcctgcgttccaacgtcctcctgtcttttgatgacacc cctgagaaggacagcttcagagcacggagcaccagtctcaatgagaggcccaaaagtttg aggatagccagagcccccaaacaaggcctgagtaactctccacctgtgaaggagttcaag gagagctgtgccgccgaggccttccggtgccgcagcatcagtgtgtctgaacatgtggtc cgcagcaggatacagacatcgctcaccagtgccagtctagggtctgcagatgagaactcc atggcccaggctgatgacaacttgaaaaatctccacctagagctcacagaaacatgtctg gacatgatggctcgatatgtgttttccaactttactgcagtacccaagaggtctcctgtg ggagagttcctcctggcaggtggcaggaccaaaacctggctggttgggaacaagcttgtt accgtgactacaagtgtggggactgggacccgatcattgctgggcttggactcgggggag ctgcagggcagcccagagtcaagctctgagcctggtgtgcatgtgagacggacaaaggag gcgccagctaagctggagtcccaggctgggcagcaggtatcccgtggggcccgagaccgg gtccgctccatgtcaggtggccatggccttcgagttggtgccctggacatacaaacccct cacatcacaggtggccccacttctccaggaccacaacagactatacccgccacaaagcct gagaaggcctctgcaggtacccaggttccagctccagagaagacaaacctagcagcctac gtgcccctgctgacccagggctgggccgagatcttggtgcggaggcctacagggaacacc agctggctgatgagcctggagaacccactcagccccttctcctcggacatcaataacatg cccctgcaggagctgtccaatgccctcatggctgccgagcgctttaaggagcaccgcgac acggctctgtacaagtcgctgtcggtgccagcagctggcacgtccaagcctcctcctctc ccacgctctaacacaggcactgtccttccaggccacaccttggcccttctgtgtgggtac agatggcgcttggcagctgaggatgtttgcgtgtgggaagttggcaagcactgccctccc ctgccacttggagagccgagagccctgtgcgccggccctggccgccgctggcccgcccct ctctcctctccaggctcgggtctgtgcctgtcctctgctcggcctgtgcagtctctgctg ctgacgcggccgctcgcgtggttgccttgcagtggcctctctgtcctccctgtaccagtc cagctgccaaggacagctgcacaggagcgtttcctggactctgctgtggttctggaagag ggaaatcaaggccgtgctcacatgcccacgggaccccctgagttggaggacttcgaggca gtgctaggtgctgacaggtcctgcccgtatcctgttacttacagcaggtcgtcctcagcc tccagtcaggaagagaagtcatcccacacagaggagctggctgccgggggcatccccatc gagcgggccatctcttccgagggtggccggccctccgtggacctctcctttcagccttcg cagcccctaagcaagtccagctcctcacctgagctgcagactcttcaggacatccttggg gaccctggggacaaggctgatgtgggccggctgagtcctgaggccaaggcccggtcccag tcagggatcttggatggggaaggggctgcttggtcagtcccaggtgaagagaaccagggc ccagccccacctgagggttccttgccatccagttcccctcgctcgcccagtggcctgcgg ccccgaggctataccatctctgattcagccccatcgcgcagaggccagagggtggagaga gataccttcaagagcagggcggcagcttccagtgctgagaaagtgccaggcatcaacccc agctttgtgttcctgcagctctaccattcacctttttttggtgatgagtccaacaagcca atcctgctgcccaatgagtccttcgagcggtcagtgcaactccttgaccagatcccgtca tatgacacacacaagattgccgtcctgtatgtgggagaaggccagagcggcagtgagctg gccatcctgtccaatgagcatggctcctacaggtacacggagttcctgacgggcctgggc aggctcattgagctcaaggactgtcagcctgacaaggtatacctgggcggcctagatgtg tgcggcgaggatggccagttcacctattgctggcatgatgacatcatgcaagccgtcttt cacatcgccaccttgatgcccaccaaggatgtggacaagcaccgttgtgataagaagcga cacctgggcaatgactttgtctccattgtctataatgactctggtgaggacttcacgctg ggcaccatcaagggccagttcaactttgtccatgtgatcatcacacccctggactacgag tgcaacctgctgactttgcagtgcaggaaagatatggagggccttgtggataccagtgtg gccaagatcgtgtctgaccgcaacctgccgtttgtggcccgccagatggccctacatgca aatatggcctcacaggtgcaccatagccgttccaaccccactgacatctacccctccaag tggatcgcacggctccgccatatcaagcggctccgccagcggatccgggaggaggcgcac tactccagccccagcctgcctctgatgcacccctcagcccacgccaaagccccagcacca actgagcccacaaccacctatgaaacaggccaacgaaagcgcctcatctcctctgtggat gacttcacagagtttgtgtga

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