Castor canadensis (American beaver): 109691000 Help Entry 109691000         CDS       T04791                                  Symbol Tsc1 Name (RefSeq) LOW QUALITY PROTEIN: hamartin   KO K07206   tuberous sclerosis 1 Organism ccan  Castor canadensis (American beaver) Pathway ccan04072   Phospholipase D signaling pathway ccan04140   Autophagy - animal ccan04150   mTOR signaling pathway ccan04151   PI3K-Akt signaling pathway ccan04152   AMPK signaling pathway ccan04211   Longevity regulating pathway ccan04218   Cellular senescence ccan04714   Thermogenesis ccan04910   Insulin signaling pathway ccan05163   Human cytomegalovirus infection ccan05165   Human papillomavirus infection ccan05168   Herpes simplex virus 1 infection ccan05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     109691000 (Tsc1)    04151 PI3K-Akt signaling pathway     109691000 (Tsc1)    04152 AMPK signaling pathway     109691000 (Tsc1)    04150 mTOR signaling pathway     109691000 (Tsc1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     109691000 (Tsc1)  09150 Organismal Systems   09149 Aging    04211 Longevity regulating pathway     109691000 (Tsc1)   09159 Environmental adaptation    04714 Thermogenesis     109691000 (Tsc1)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     109691000 (Tsc1)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     109691000 (Tsc1)    05165 Human papillomavirus infection     109691000 (Tsc1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hamartin Motif Other DBs NCBI-GeneID:  109691000 NCBI-ProteinID:  XP_020026271 UniProt:  A0A8B7V2S8 LinkDB All DBs Position Unknown AA seq 1156 aa AA seqDB search MAQPANVGELLSMLDSPTLGVRDDVTAIFKENLNSDRGPMLVNTLVDYYLETNSQPVLHI LTTLQEPHDKHLLDKMNEYVGKATTRLSILSLLGHVVRLQPSWKHKLSQAPLLPSLLKCL KMDSDVVVLTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVTEVYLVHL HASVYALFHRLYGMYPCNXVSFLRSHYSMKENLETFEEVVRPMMEHVRIHPELVTGSKDH ELDPRRWKKLETHDVVIECAKISLDPTEAAYEDGCYVSHQLSAHFPHRSADGTASPYVHT QNSYGSATSTPYSTSQMTFCAPGQLPQTLSSPSTRLLPEPLQATLWSPSMVCGMTTPPTS PGNVPPDFSHPYSKVFGTTAGKGTPLGTPATSPPPAPICHPDDYVHISLPQATTTPPRKE ERTDSARPCLHRQHHLPNDRGLEELPGSKGSVTLSDLPVFLGDLASEEDSIEKDKEEAAI SRELSEITTTEADPVVPRGGFDSPFYRDSLPGSQRKTLSASSGTRGSSVNPEPLPSSLDK RGLDTPKQAFTPIDIPCGSADISPAGDRDRQTSLETSILTPSPCKIPPRRGVGFGSGQPP PYDHLFEVALPKTARHFVSKKTEELLKKVKGCPEEDYVPSTSPMEVLDRLIQQGADAHSK ELNKLSLPSKSVDWTHFGDEIRTLRDQLLLLHNQLHYERFKRQQHALRNRRLLRKVIRAA ALEEHNAAMKDQLKLQEKDIQIWKVSLQKEQARYSQLQEQRDTVVTQLHSQIRQLQHDRE EFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVSQKLSNSESVQQQMEF LNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVLQQNQRLDTSQK RILELESLLAKKDHLLLEQKKYLEDVKSQASEQLLAAESRYEAQKRITRVFELEILDLYG RLEKDDLLQKLEEEKAEAVEAVEERLDCCNDGCSDLGHNEEASGHNGETKTLRPSGTRGS CGAKGAGGSSSSSSELSTPEKPTSQRAGPFSSRWETSVGEPSTSIPTTVGSLPSSKSFLG MKARELFRNKSESQCDEDSMTISSPSETLKTELGKDLGMEVQSPLNLDGPHPSPPTPDSV GQLRIMDYNETHLEHS NT seq 3471 nt NT seq  +upstreamnt  +downstreamnt atggctcagccagcaaacgttggggagctgctctccatgctggactctcccacactgggt gtgcgcgatgatgtgacagccatctttaaggagaacctcaattctgaccgtggtcctatg cttgtgaacaccctggtggattattatctggaaaccaattctcagccggttttgcacatc ttgactactttgcaagagccacatgataagcacctcttggacaaaatgaatgaatatgtg ggcaaagccaccactcgtttatccatcctctcattgctggggcatgtcgtgaggctgcag ccatcttggaagcataagctctctcaagcacctcttttgccttctttactgaaatgtctc aagatggactctgatgttgtcgtcctcacaacaggtgtcttggttttgattaccatgcta ccaatgatcccgcagtcagggaagcagcaccttcttgatttcttcgatatctttggccgt ctttcgtcatggtgcctgaagaaaccaggtcatgtgacagaagtctaccttgtccatctc catgccagtgtttatgccctctttcatcgcctttatggaatgtacccttgcaacnttgtc tcttttttgcgttctcactacagtatgaaggaaaacttagagacttttgaagaagtggtc aggccaatgatggagcatgtgcgaattcacccggaattagtgactggatccaaggaccat gaactggaccctcgaaggtggaagaaactagaaactcatgatgttgtaatagagtgtgcc aaaatctccctggaccccacagaagccgcctatgaagatggctgttatgtgtctcaccag ctctctgcccacttccctcatcgttcagctgatggcaccgccagcccttatgtccacaca cagaatagctatggcagtgctacttctaccccttattccacctctcagatgacgttctgt gcacctgggcagctacctcagactctgagctccccatcaacacggctgttacctgagccg ctgcaagctactctttggagcccttctatggtctgtggcatgaccactcctccaacatct cctggaaatgtcccgcctgatttctcacacccttatagtaaagtctttggcacaactgct ggaaaaggaactcctctgggaaccccagcaacctctcctcctccagccccaatctgccat ccagatgactatgtacacatttcactcccccaggccacaaccacaccccccaggaaggaa gagagaacagattctgcaaggccgtgtctacataggcagcaccatcttccgaatgacaga ggattagaagagctacctggaagcaaaggttccgttactctaagtgatcttccggtgttt ttaggtgatctggcctctgaggaagacagtattgaaaaagataaggaagaagcggcgata tctagagagctttctgagatcaccaccacagaggcggatcctgtggttcctcgagggggc tttgactctcctttctaccgagacagtctccctggttctcagcggaagacactttcagca tcgtctgggactcggggctccagtgtgaaccctgagcctttaccctcctccctggacaag cgtgggctcgatacaccaaagcaagcctttactcccattgacataccctgtggcagtgct gacatcagtccagctggggatagggaccgccagacttctctggagaccagtattctcact cccagcccttgcaaaattcctcctcggaggggagtgggctttggaagtgggcaacctccc ccatacgatcatctctttgaggtggccttgccaaagactgcccgtcactttgtcagcaag aagaccgaggagctgttaaagaaagtgaaaggatgccctgaggaagactatgtgccctct acctccccaatggaagtactggacaggctgatacagcagggagcagacgcacacagcaag gaactgaacaaattgtccttacccagcaagtctgtggactggacccattttggagatgag atccgcaccctccgagaccagttgcttttactgcacaaccagttacactacgagcgtttt aagaggcaacaacatgctcttcggaacaggcggctcctgagaaaggtgatcagagcagct gctctggaggaacacaatgctgctatgaaagatcagttgaagttacaagagaaagatatc cagatatggaaggtgagtctgcagaaagagcaagccagatacagtcagcttcaggagcag cgtgacactgtggtgacccagctgcacagccagatcagacagctacaacatgaccgagaa gaattctacaaccagagccaggaattgcagacaaagctggaagactgcaggaacatgatc gcagagctgcgaatagagctgaaaaaggccaacaacaaggtgtgtcacaccgagctgctg ctcagtcaggtttctcaaaagctctcaaatagtgagtcggtccagcagcagatggagttc ttgaacaggcagttgttggtgcttggggaggtcaacgagctgtatttggaacaactgcag aacaagcactcagacaccacaaaggaagtagaaatgatgaaagccgcatatcgcaaagaa ctagaaaagaacagaagccatgttctccagcagaatcagaggctcgatacctcccagaaa cggattttggaactggaatctcttctggccaagaaagaccaccttcttctggaacagaag aaatatctggaggatgtcaagagccaggcaagtgaacaactgctggctgcagagagcagg tatgaggctcaaaaaaggatcacccgggtgtttgagttggagatcttagacttgtatggc aggttggagaaagatgacctcctacaaaaactcgaagaggaaaaagcagaagcagtggaa gcagtggaagaaaggcttgactgttgtaatgacggctgctcagatttagggcacaatgaa gaggcatctgggcacaatggtgagaccaagaccctcagacccagtggtaccagaggcagt tgtggagctaaaggagctggaggcagcagcagcagcagcagtgagctttctaccccagag aaacccacaagccagagagcaggcccattcagcagtcggtgggaaacttctgtgggcgag ccctccaccagcatccctacaactgttggttcacttcccagttccaaaagcttcctgggc atgaaggcccgagagctgtttcgtaataagagcgagagccagtgtgatgaggacagcatg accatcagtagcccttctgagactctaaagacagaactgggcaaagacttgggtatggaa gtccagagtcccctgaacctagacggccctcacccatctcccccaaccccggacagtgtt gggcagctccgtatcatggactacaatgagactcatcttgaacacagctaa

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