Castor canadensis (American beaver): 109691424 Help Entry 109691424         CDS       T04791                                  Symbol Tgfbr1 Name (RefSeq) TGF-beta receptor type-1   KO K04674   TGF-beta receptor type-1 [EC:2.7.11.30] Organism ccan  Castor canadensis (American beaver) Pathway ccan04010   MAPK signaling pathway ccan04060   Cytokine-cytokine receptor interaction ccan04068   FoxO signaling pathway ccan04144   Endocytosis ccan04218   Cellular senescence ccan04350   TGF-beta signaling pathway ccan04371   Apelin signaling pathway ccan04380   Osteoclast differentiation ccan04390   Hippo signaling pathway ccan04520   Adherens junction ccan04659   Th17 cell differentiation ccan04926   Relaxin signaling pathway ccan04933   AGE-RAGE signaling pathway in diabetic complications ccan05142   Chagas disease ccan05161   Hepatitis B ccan05166   Human T-cell leukemia virus 1 infection ccan05200   Pathways in cancer ccan05210   Colorectal cancer ccan05212   Pancreatic cancer ccan05220   Chronic myeloid leukemia ccan05225   Hepatocellular carcinoma ccan05226   Gastric cancer ccan05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109691424 (Tgfbr1)    04350 TGF-beta signaling pathway     109691424 (Tgfbr1)    04390 Hippo signaling pathway     109691424 (Tgfbr1)    04371 Apelin signaling pathway     109691424 (Tgfbr1)    04068 FoxO signaling pathway     109691424 (Tgfbr1)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     109691424 (Tgfbr1)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     109691424 (Tgfbr1)   09143 Cell growth and death    04218 Cellular senescence     109691424 (Tgfbr1)   09144 Cellular community - eukaryotes    04520 Adherens junction     109691424 (Tgfbr1)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     109691424 (Tgfbr1)   09152 Endocrine system    04926 Relaxin signaling pathway     109691424 (Tgfbr1)   09158 Development and regeneration    04380 Osteoclast differentiation     109691424 (Tgfbr1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109691424 (Tgfbr1)   09162 Cancer: specific types    05210 Colorectal cancer     109691424 (Tgfbr1)    05212 Pancreatic cancer     109691424 (Tgfbr1)    05225 Hepatocellular carcinoma     109691424 (Tgfbr1)    05226 Gastric cancer     109691424 (Tgfbr1)    05220 Chronic myeloid leukemia     109691424 (Tgfbr1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     109691424 (Tgfbr1)    05161 Hepatitis B     109691424 (Tgfbr1)   09174 Infectious disease: parasitic    05142 Chagas disease     109691424 (Tgfbr1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     109691424 (Tgfbr1)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     109691424 (Tgfbr1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ccan01001]     109691424 (Tgfbr1) Enzymes [BR:ccan01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.30  receptor protein serine/threonine kinase      109691424 (Tgfbr1) Protein kinases [BR:ccan01001]  Receptor serine/threonine kinases (RSTK): TKL group   TGFBR1 family [OT]    109691424 (Tgfbr1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2 Haspin_kinase Motif Other DBs NCBI-GeneID:  109691424 NCBI-ProteinID:  XP_020026991 UniProt:  A0A8B7V4U3 LinkDB All DBs Position Unknown AA seq 429 aa AA seqDB search MEAAAAAPRRRLLFLVLAAAAAATVLPGATALQCFCHLCTKDNFTCVTDGLCFVSVTETT DKVIHNSMCIAEIDLIPRDRPFVCAPSSKSGVTTTPYCCNQDHCNKIELPTTVKQSPGLG PVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIY DMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSW FREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGM IKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSAT DTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGKLL SFPPTVCPK NT seq 1290 nt NT seq  +upstreamnt  +downstreamnt atggaggcggcagccgctgctccgcgtcgccgcttgcttttcctcgtgttggcggcggcg gcggcggcgacagtgctcccgggggcgacggcattacagtgtttttgccacctgtgtaca aaagacaattttacctgtgtgacagatggactctgctttgtctctgtcacagagactaca gataaagttatacacaatagcatgtgcatagctgaaattgacctaattcctcgagatagg ccatttgtatgtgcaccttcttcaaaaagtggagttactactacaccatattgctgcaat caggaccactgcaataaaatagagctcccaactactgtgaagcaatcacctggccttggt cctgtcgagctggcagctgtcattgctggaccagtctgcttcgtctgtatctcactcatg ttgatggtctatatctgccataaccgcactgtcattcaccatcgagtgccaaatgaagag gatccttcattagatcgcccttttatttcagagggtactacattaaaagatttaatttat gatatgacaacatcggggtctggatcaggtttaccgttgctcgttcagagaacaattgca agaactattgtattacaagaaagtattggcaaagggcgatttggagaagtctggcgagga aaatggcggggagaagaagttgctgtgaagatattctcctctagagaagagcgttcatgg ttccgtgaggcagagatttatcaaactgtaatgttacgccatgaaaacatcctgggattt atagcagcagacaacaaagacaatggtacatggactcagctctggttggtgtcagattat cacgagcatggatccctttttgattacttaaacagatacacagttactgtggaaggaatg atcaaactcgctttgtccacagcaagtggtcttgcccatcttcacatggagattgttggt acccaaggaaaaccagccattgctcatagagatttgaaatcaaagaatatcttagtgaag aagaatggaacctgctgtattgcagacttaggactggcagtaagacacgattcagccacg gatacaattgatattgctccaaaccacagagtaggaacaaaaaggtacatggcccctgaa gttctagatgattccataaatatgaaacattttgaatccttcaaacgtgctgacatctat gcaatgggcttagtattctgggaaatcgctcgacgatgttccattggtggtaaattgctc tcctttcccccaacagtttgtcctaaatag

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