Castor canadensis (American beaver): 109691649
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Entry
109691649 CDS
T04791
Symbol
Fgfr2
Name
(RefSeq) fibroblast growth factor receptor 2 isoform X1
KO
K05093
fibroblast growth factor receptor 2 [EC:
2.7.10.1
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan01521
EGFR tyrosine kinase inhibitor resistance
ccan04010
MAPK signaling pathway
ccan04014
Ras signaling pathway
ccan04015
Rap1 signaling pathway
ccan04020
Calcium signaling pathway
ccan04144
Endocytosis
ccan04151
PI3K-Akt signaling pathway
ccan04550
Signaling pathways regulating pluripotency of stem cells
ccan04810
Regulation of actin cytoskeleton
ccan05200
Pathways in cancer
ccan05215
Prostate cancer
ccan05226
Gastric cancer
ccan05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109691649 (Fgfr2)
04014 Ras signaling pathway
109691649 (Fgfr2)
04015 Rap1 signaling pathway
109691649 (Fgfr2)
04020 Calcium signaling pathway
109691649 (Fgfr2)
04151 PI3K-Akt signaling pathway
109691649 (Fgfr2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
109691649 (Fgfr2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
109691649 (Fgfr2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
109691649 (Fgfr2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
109691649 (Fgfr2)
05230 Central carbon metabolism in cancer
109691649 (Fgfr2)
09162 Cancer: specific types
05226 Gastric cancer
109691649 (Fgfr2)
05215 Prostate cancer
109691649 (Fgfr2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
109691649 (Fgfr2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccan01001
]
109691649 (Fgfr2)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ccan04090
]
109691649 (Fgfr2)
00536 Glycosaminoglycan binding proteins [BR:
ccan00536
]
109691649 (Fgfr2)
Enzymes [BR:
ccan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
109691649 (Fgfr2)
Protein kinases [BR:
ccan01001
]
Receptor tyrosine kinases (RTK)
FGFR family [OT]
109691649 (Fgfr2)
CD molecules [BR:
ccan04090
]
Proteins
109691649 (Fgfr2)
Glycosaminoglycan binding proteins [BR:
ccan00536
]
Heparan sulfate / Heparin
Growth factors/receptors
109691649 (Fgfr2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
I-set
Ig_3
ig
Ig_2
V-set
Ig_5
ABC1
C2-set_2
V-set_CD47
DUF5527
Pkinase_fungal
Kinase-like
Motif
Other DBs
NCBI-GeneID:
109691649
NCBI-ProteinID:
XP_020027375
UniProt:
A0A8B7V957
LinkDB
All DBs
Position
Unknown
AA seq
820 aa
AA seq
DB search
MVCWGHFICLVVVTMATVSLARPPFSLVEETTLEPEEPPTKYQISQPEVYVAAPGESLEL
RCLLKDAAVISWTKNGVHLGPGNRTVLIGEYLQIKGATPRDSGLYACTAARTVDSETWYF
MVNVTDAISSGDDEDDTDGSEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCP
AGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSI
NHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSK
YGPDGLPYLKVLKHSGINSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPK
QQAPVREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKTTTKKPDFSSQPAVHKLT
KRIPLRRQVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKL
TLGKPLGEGCFGQVVMAEAVGIDKDKPKEAATVAVKMLKDDATEKDLSDLVSEMEMMKMI
GKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFK
DLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTT
NGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHR
MDKPANCTSELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLTQPLEQYSP
SYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSIKT
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atggtctgctggggtcacttcatctgcctggttgtggtcaccatggcaacggtgtccctg
gcccggccccccttcagtttagttgaggaaaccacgttagagccggaagagccaccaacc
aaataccaaatctctcaacctgaagtttacgtggccgcgccaggggagtcactagagttg
cgctgcctgttgaaagatgctgccgtgatcagttggactaagaatggggtacacttgggg
cccggcaataggacagtgcttattggggagtacttgcagataaaaggcgccacacctaga
gactccggcctctatgcttgtactgctgctaggactgtagacagtgaaacttggtacttc
atggtcaatgtcacagatgccatctcgtccggagatgacgaggatgacacagatggctcc
gaagattttgtcagtgagaacagtaacaacaagagagcaccatactggaccaacacagaa
aagatggagaaacggctgcacgctgttcccgcggccaacacagtcaagttccgctgtcca
gctggaggcaatccaacgcccacgatgaggtggctgaaaaatggcaaagagttcaagcag
gagcatcgcattggaggctataaggtccgaaaccagcactggagcctgattatggaaagc
gtggtcccttctgacaagggaaattacacctgtgtggtagagaatgaatacggctccatc
aatcacacataccacctagacgttgttgagcgatcgccacaccggcccatcctccaagct
ggactgccagcaaatgcgtccacagtggtcggaggggacgtggagtttgtctgcaaagtt
tacagcgatgcccagccccacatccagtggatcaagcatgttgaaaagaatggcagtaaa
tatgggcctgacgggctaccctacctcaaggttctgaagcactcggggataaatagttcc
aatgcagaagtgctggctctgttcaatgtcactgaggcggatgccggggagtatatatgt
aaggtctccaattatataggacaggccaaccagtctgcctggctcactgtcctgcccaag
cagcaagctcctgtaagagaaaaggagattacagcttccccagattacctggagatagcc
atttactgcataggggtcttcttaatcgcctgtatggtagtgacagtcatcctgtgccga
atgaagaccacgaccaagaagccagacttcagcagccagccagctgtgcacaagctgacc
aaacgcatccccctgcggagacaggtttcggctgagtccagctcctccatgaactccaac
accccactggtaaggataacaacacgcctgtcttcaacagcagacaccccgatgctggca
ggggtctctgagtatgaactcccagaggatccaaagtgggagttccccagagataagctg
acgctgggcaaacccctgggggaaggttgctttgggcaagtggtcatggctgaagcagtg
ggaattgacaaagacaagcccaaggaggcagccactgtggcagtgaagatgttgaaagat
gatgccacagagaaggacctttctgacctggtgtcagagatggagatgatgaaaatgatt
ggaaaacacaaaaatatcatcaatcttctgggagcctgcacacaggacgggccactctat
gtcatagttgagtacgcttcaaaaggcaacctccgggaatacctgcgggcccggaggcca
cctggcatggagtactcctatgacattaaccgcgttcccgaggagcagatgaccttcaag
gacttggtgtcgtgcacctaccagctggccagaggcatggagtacttggcttcccaaaaa
tgtatccatcgggatttagcagccagaaacgtgttggtaacggagaacaatgtgatgaag
atagctgactttggactggccagagatatcaacaacatagactattacaaaaaaaccaca
aacgggcgacttccggtcaagtggatggctcccgaagccctttttgatagagtgtacaca
caccagagtgatgtctggtcctttggggtgttaatgtgggagatcttcaccttagggggt
tcgccctacccggggattcccgtggaggaacttttcaagctgctgaaggaaggacacagg
atggataagccagccaactgcaccagtgagctgtatatgatgatgagggactgctggcat
gccgtgccttcacagagaccaactttcaagcagttggtagaagacttggaccgaattcta
accctcacaaccaatgaggaatacttggacctcactcagcctctcgagcagtattctcct
agttaccccgacacaaggagttcttgttcttcaggagatgactctgtgttttctccggac
cccatgccttacgaaccctgtctgcctcagtatccacacataaatggcagcattaaaaca
tga
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