KEGG   Castor canadensis (American beaver): 109692052
Entry
109692052         CDS       T04791                                 
Symbol
Map2k3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan04010  MAPK signaling pathway
ccan04015  Rap1 signaling pathway
ccan04218  Cellular senescence
ccan04620  Toll-like receptor signaling pathway
ccan04664  Fc epsilon RI signaling pathway
ccan04668  TNF signaling pathway
ccan04714  Thermogenesis
ccan04750  Inflammatory mediator regulation of TRP channels
ccan04912  GnRH signaling pathway
ccan04935  Growth hormone synthesis, secretion and action
ccan04936  Alcoholic liver disease
ccan05014  Amyotrophic lateral sclerosis
ccan05022  Pathways of neurodegeneration - multiple diseases
ccan05132  Salmonella infection
ccan05135  Yersinia infection
ccan05145  Toxoplasmosis
ccan05161  Hepatitis B
ccan05169  Epstein-Barr virus infection
ccan05170  Human immunodeficiency virus 1 infection
ccan05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ccan05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109692052 (Map2k3)
   04015 Rap1 signaling pathway
    109692052 (Map2k3)
   04668 TNF signaling pathway
    109692052 (Map2k3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    109692052 (Map2k3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    109692052 (Map2k3)
   04664 Fc epsilon RI signaling pathway
    109692052 (Map2k3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    109692052 (Map2k3)
   04935 Growth hormone synthesis, secretion and action
    109692052 (Map2k3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    109692052 (Map2k3)
  09159 Environmental adaptation
   04714 Thermogenesis
    109692052 (Map2k3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109692052 (Map2k3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    109692052 (Map2k3)
   05161 Hepatitis B
    109692052 (Map2k3)
   05169 Epstein-Barr virus infection
    109692052 (Map2k3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109692052 (Map2k3)
   05135 Yersinia infection
    109692052 (Map2k3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    109692052 (Map2k3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    109692052 (Map2k3)
   05022 Pathways of neurodegeneration - multiple diseases
    109692052 (Map2k3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109692052 (Map2k3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109692052 (Map2k3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccan01001]
    109692052 (Map2k3)
Enzymes [BR:ccan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     109692052 (Map2k3)
Protein kinases [BR:ccan01001]
 Serine/threonine kinases: STE group
  STE7 family
   109692052 (Map2k3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 Choline_kinase APH RIO1 DUF4344
Other DBs
NCBI-GeneID: 109692052
NCBI-ProteinID: XP_020028014
UniProt: A0A8C0ZQX8
LinkDB
Position
Unknown
AA seq 347 aa
MESPASSQPASMPQSKGKSKRKKDLRIACVSKPPVPNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMTIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggagtcgcctgcctcgagccagcccgccagcatgccccagtccaaaggaaaatccaag
aggaaaaaggatttacgaatagcctgtgtgtccaagccacctgtgcccaaccccacaccc
ccccggaacctggactcccggaccttcatcaccatcggagacagaaactttgaggtggag
gccgatgacttggtgaccatatcagagctgggccgtggagcctatggggtggtggagaag
gtgcgacatgcccagagtggcactatcatggctgtgaagcgcatccgggccactgtgaac
tcgcaggagcagaagaggctgctcatggacctggacatcaacatgcgcacggttgactgc
ttctacactgtcaccttctatggggccctcttcagagagggagatgtgtggatctgcatg
gagctcatggacacgtctctggacaagttctaccggaaggtgctggataaaaacatgacg
attccagaggatattctgggggagattgctgtgtctattgttcgagccctggaacaccta
cacagcaagctgtctgtgatccacagagatgtgaagccgtccaatgtcctcatcaacaag
gagggccatgtgaagatgtgtgacttcggcatcagtggctacctggtggactccgtggca
aagacaatggatgctggctgcaagccctatatggctcctgagagaatcaaccctgagctg
aaccagaaaggctacaatgtcaagtctgatgtctggagtctcggcatcaccatgattgag
atggccattctgaggttcccttatgagtcctggggaaccccgttccagcagctgaaacag
gtggtggaggagccatccccccagctcccagctgaccgattctctcctgagtttgtggac
ttcactgcccagtgcctgaggaagaaccctgcggagcgcatgagttacctagagctaatg
gagcaccctttcttcaccttgcacaaaaccaagaagacagacattgctgccttcgtgaag
gagatcctgggagaggactcgtag

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