Castor canadensis (American beaver): 109693015 Help Entry 109693015         CDS       T04791                                  Symbol Nos2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism ccan  Castor canadensis (American beaver) Pathway ccan00220   Arginine biosynthesis ccan00330   Arginine and proline metabolism ccan01100   Metabolic pathways ccan04020   Calcium signaling pathway ccan04066   HIF-1 signaling pathway ccan04146   Peroxisome ccan04371   Apelin signaling pathway ccan04926   Relaxin signaling pathway ccan05010   Alzheimer disease ccan05014   Amyotrophic lateral sclerosis ccan05022   Pathways of neurodegeneration - multiple diseases ccan05133   Pertussis ccan05140   Leishmaniasis ccan05142   Chagas disease ccan05145   Toxoplasmosis ccan05146   Amoebiasis ccan05152   Tuberculosis ccan05200   Pathways in cancer ccan05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:ccan00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     109693015 (Nos2)    00330 Arginine and proline metabolism     109693015 (Nos2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     109693015 (Nos2)    04066 HIF-1 signaling pathway     109693015 (Nos2)    04020 Calcium signaling pathway     109693015 (Nos2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     109693015 (Nos2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     109693015 (Nos2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109693015 (Nos2)   09162 Cancer: specific types    05222 Small cell lung cancer     109693015 (Nos2)   09171 Infectious disease: bacterial    05133 Pertussis     109693015 (Nos2)    05152 Tuberculosis     109693015 (Nos2)   09174 Infectious disease: parasitic    05146 Amoebiasis     109693015 (Nos2)    05145 Toxoplasmosis     109693015 (Nos2)    05140 Leishmaniasis     109693015 (Nos2)    05142 Chagas disease     109693015 (Nos2)   09164 Neurodegenerative disease    05010 Alzheimer disease     109693015 (Nos2)    05014 Amyotrophic lateral sclerosis     109693015 (Nos2)    05022 Pathways of neurodegeneration - multiple diseases     109693015 (Nos2) Enzymes [BR:ccan01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      109693015 (Nos2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  109693015 NCBI-ProteinID:  XP_020029612 UniProt:  A0A8B7VDT4 LinkDB All DBs Position Unknown AA seq 1171 aa AA seqDB search MACPWKFLFKARSHQYNLTEEKDINNNVGKAMGAISSPSTQDDPKCHSPSKHQNGFPQPL IGVAKSPEPLDKLHMPASTCQQYMRIKNWGSGVSFQDTLHQKAKSDLACKSKSCQGSIMN PKSLTRGPRDKPTSVDELLPQAIEFINQYYSSFKEAKIEEHLARVEAVTKEIETTGTYRL TGDELIFATKLAWRNAPRCIGRIQWSNLQVFDARSCTTAQEMFEHICRHLHYATNSGSIR SAITVFPQRSDGKHDFRVWNTQLIRYAGYQMPDGTIRGDPANLEFTQLCIDLGWKPRYGR FDVLPLVLQANGRDPELFEIPPDLVLEVPMEHPKYEWFQELELKWYALPAVANMLLEVGG LEFPGCPFNGWYMGTEIGVRDFCDTQRYNILEEVGRRMGLETHTLASLWKDRAVTEINVA VLHSFQKHNVTIMDHHSAAESFMKHMQNEYRLRGGCPADWIWLVPPISGSITPVFHQEML NYVLSPFYYYQVEPWKTHVWQDKKQRPGRRELRFQVLVKAVLFSSILIRKIMASRVRVTI LYATETGRSEALAQDLGTLFSCAFNPKVLCMDEYRLSNLEEEQLLLVVTSTFGNGDSPGN GETLKKSLFTLKELTNTFRYAVFGLGSSMYPQFCAFAHDIDQKLSQLGASQLTPTGEGDE LSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSSATWEAQNYRLVQNSQSFELH KALGSVHSKHVFTLRLKSQQNLQSPKSSRTTLLVELSCKDSPGLSYLPGEHLGVFPSNQP ALVQGILERVVDSPKPHQTVCLEALDKSGSYWVRDKRLPPCSLSQALTYFLDITTPPTQL QLQKLAQLATEEAERQRLETLGQPSEYNKWKFTNSPTFLEVLEEFPSLRVPAAFLLSQLP ILKPRYYSISSSQDHTPTEVHLTVAVVTYRTRDGQGPLHHGVCSTWLSSLKPQDPVPCFV RSAKGFQLPKDPSQPCILIGPGTGIAPFRSFWQQRLHDSQHKGLKGGHMTLVFGCRCPDE DHLYWEEMLEMARKGVLHELHTAYSRLPGKPKVYVQDLLRQQLAGEVLRVLHEEPGHLYV CGDVRMARDVVHTLKQLVADSLNLNEEQVEDYFFQLKSQRRYHEDIFGAVYSYQVRKDRT AGQTSDGEVEAAGMKYNNGDTVELWSTALRR NT seq 3516 nt NT seq  +upstreamnt  +downstreamnt atggcctgtccctggaagtttctgttcaaggccagatcccaccagtataacttgactgag gaaaaggacatcaacaacaatgtggggaaagctatgggtgccatctccagtccttcgaca caggatgaccccaagtgtcacagccccagcaaacaccagaatggattcccacaacccctc ataggggtggcaaagtctccagaacccctggacaaactgcatatgcctgcatcaacttgc cagcagtatatgaggatcaaaaactggggcagtggggtgtcattccaagacacacttcac caaaaggccaaatcggatttagcctgcaagtcaaaatcttgccaggggtccatcatgaac cccaaaagtttgaccagaggacccagggacaagcctacctctgtggatgagcttctacct caggctattgaatttatcaaccagtattacagctccttcaaagaggcaaaaatagaggaa catctggccagggttgaggcggtcacaaaggagatagaaacaacaggaacctaccggctg acgggggatgagctcatctttgccaccaagctcgcctggcgcaacgccccccgctgcatt ggcaggatccagtggtccaacctgcaggtcttcgacgcccggagctgtaccacagcccag gagatgtttgaacacatctgcagacacctgcactacgccaccaacagcggcagcatcagg tcggctatcacagtgttcccccagcggagtgatgggaagcatgacttccgggtgtggaat acacagctcatccgctacgctggctaccagatgcctgatggcaccatcagaggggaccct gccaacctggagttcacccagctgtgcatcgatctgggctggaagccccgctatggccgc tttgatgtgctgcctctggtcctgcaggctaacggccgtgaccctgaacttttcgaaatt cctcctgaccttgtgctcgaagtgcccatggaacatcccaagtatgagtggttccaggag ctggagctgaagtggtatgccctgcctgctgtggctaacatgctgctcgaagtgggtggc ctcgagttcccggggtgccccttcaatggctggtacatgggcaccgagattggagtccgg gacttctgtgacacccagcgctataacatcctagaggaagtgggcagaaggatgggtctg gagacacacacgctggcctccctctggaaagaccgagctgtcacagagatcaatgtcgct gtgctgcacagtttccagaagcacaatgtgaccatcatggaccaccactcggctgcagag tccttcatgaagcacatgcagaatgagtaccggttacgtggcggctgcccggccgactgg atttggctggtccctccaatttctgggagcatcacccccgtgtttcaccaggagatgttg aattacgtgctgtccccattctactactatcaggtggagccctggaagacccatgtctgg caggacaagaagcagagacctgggagaagagagctccgattccaagtcttggtgaaagct gtgcttttctcctctatactgatacgtaagattatggcgtcccgagtcagagtcacaatc ctctacgcaactgagacaggaaggtcagaagcactggcccaggacctggggaccttgttc agctgtgccttcaaccccaaggttctctgcatggatgagtacaggctgagcaacctggag gaggagcagctactgctggtggtgaccagcacgtttgggaatggagactcccctggcaat ggcgagacactgaagaaatccctcttcacgctgaaagagctcaccaacaccttcagatac gctgtgtttggccttggctccagcatgtacccacaattctgtgcctttgctcatgacatc gaccagaagttgtcccagctgggggcctctcagctcaccccaacaggggaaggggacgag ctcagtgggcaggaggacgccttccgcagttgggccgtgcaaaccttcaaggcagcctgt gagacgtttgatgtccgaggcaaacagcacattcagatccctaagctctacacctctagc gcgacctgggaggcgcagaactacaggctcgtacagaactcacagtcgtttgaactccac aaagcccttggcagtgtgcactccaagcatgtgttcaccctgaggctcaaatcccagcag aatctgcagagtcccaagtccagccgtactaccctcctggtagaactctcctgcaaggac agcccaggcctgagctacctgcctggagagcacctcggggtttttccaagcaaccagcca gccttggtccaaggcatcttggagcgagtagtagatagccccaagccccaccaaaccgtg tgcctggaggccctggacaagagtggcagctactgggtcagagacaagaggctgcctccc tgctcactcagccaggccctcacctacttcctggacatcaccacccctccaacccagctg cagctccaaaagctggcccagctagccacagaagaggctgagagacagaggctggagacc ctgggtcagccctcagagtacaacaagtggaagttcaccaacagccccacgttcctggag gtgctggaggagttcccatcactgcgggtccctgctgcctttctgctgtcccagctcccc attctgaagccccgctactactccatcagttcctcccaggaccacacacccacagaggtc caccttacagtggccgtggtcacctaccgcacccgagatggtcagggtcccttgcaccac ggcgtctgcagcacttggctcagcagcctgaagccccaggacccagtgccctgttttgtg cgaagtgccaaaggcttccagcttcccaaagacccctcccaaccttgcatcctcatcggg cctggcacaggcatcgcgcccttccgcagtttctggcagcagcgactccatgactcccaa cacaaagggctcaaggggggccacatgaccctggtgttcgggtgccgctgtccagacgag gaccacctgtactgggaggagatgttggagatggccaggaagggcgtgttacatgagctg cacacagcctattctcggctgcctggcaagcccaaggtctacgttcaagacctcctgcgg cagcagctggcaggtgaggtgctccgcgtgctccatgaggagccaggccacctctatgtt tgtggggatgtgcgcatggcccgggacgtggtccacaccctgaagcagttggtggctgac agcctgaacttgaatgaggagcaggttgaggactatttcttccagctcaagagccagagg cgctatcatgaagatatctttggtgctgtctattcctaccaagtgagaaaggacaggaca gcggggcagaccagcgatggagaagttgaagctgctggaatgaaatataacaatggagac actgttgagctgtggtccacggccctaaggagatag

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