KEGG   Castor canadensis (American beaver): 109693025
Entry
109693025         CDS       T04791                                 
Symbol
Atf4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan04010  MAPK signaling pathway
ccan04022  cGMP-PKG signaling pathway
ccan04137  Mitophagy - animal
ccan04141  Protein processing in endoplasmic reticulum
ccan04151  PI3K-Akt signaling pathway
ccan04210  Apoptosis
ccan04211  Longevity regulating pathway
ccan04261  Adrenergic signaling in cardiomyocytes
ccan04668  TNF signaling pathway
ccan04720  Long-term potentiation
ccan04722  Neurotrophin signaling pathway
ccan04725  Cholinergic synapse
ccan04728  Dopaminergic synapse
ccan04911  Insulin secretion
ccan04912  GnRH signaling pathway
ccan04915  Estrogen signaling pathway
ccan04918  Thyroid hormone synthesis
ccan04922  Glucagon signaling pathway
ccan04925  Aldosterone synthesis and secretion
ccan04926  Relaxin signaling pathway
ccan04927  Cortisol synthesis and secretion
ccan04928  Parathyroid hormone synthesis, secretion and action
ccan04932  Non-alcoholic fatty liver disease
ccan04934  Cushing syndrome
ccan04935  Growth hormone synthesis, secretion and action
ccan05010  Alzheimer disease
ccan05012  Parkinson disease
ccan05014  Amyotrophic lateral sclerosis
ccan05020  Prion disease
ccan05022  Pathways of neurodegeneration - multiple diseases
ccan05030  Cocaine addiction
ccan05031  Amphetamine addiction
ccan05034  Alcoholism
ccan05161  Hepatitis B
ccan05163  Human cytomegalovirus infection
ccan05166  Human T-cell leukemia virus 1 infection
ccan05203  Viral carcinogenesis
ccan05207  Chemical carcinogenesis - receptor activation
ccan05215  Prostate cancer
ccan05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    109693025 (Atf4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109693025 (Atf4)
   04668 TNF signaling pathway
    109693025 (Atf4)
   04022 cGMP-PKG signaling pathway
    109693025 (Atf4)
   04151 PI3K-Akt signaling pathway
    109693025 (Atf4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    109693025 (Atf4)
  09143 Cell growth and death
   04210 Apoptosis
    109693025 (Atf4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    109693025 (Atf4)
   04922 Glucagon signaling pathway
    109693025 (Atf4)
   04912 GnRH signaling pathway
    109693025 (Atf4)
   04915 Estrogen signaling pathway
    109693025 (Atf4)
   04926 Relaxin signaling pathway
    109693025 (Atf4)
   04935 Growth hormone synthesis, secretion and action
    109693025 (Atf4)
   04918 Thyroid hormone synthesis
    109693025 (Atf4)
   04928 Parathyroid hormone synthesis, secretion and action
    109693025 (Atf4)
   04925 Aldosterone synthesis and secretion
    109693025 (Atf4)
   04927 Cortisol synthesis and secretion
    109693025 (Atf4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    109693025 (Atf4)
  09156 Nervous system
   04725 Cholinergic synapse
    109693025 (Atf4)
   04728 Dopaminergic synapse
    109693025 (Atf4)
   04720 Long-term potentiation
    109693025 (Atf4)
   04722 Neurotrophin signaling pathway
    109693025 (Atf4)
  09149 Aging
   04211 Longevity regulating pathway
    109693025 (Atf4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    109693025 (Atf4)
   05203 Viral carcinogenesis
    109693025 (Atf4)
  09162 Cancer: specific types
   05215 Prostate cancer
    109693025 (Atf4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109693025 (Atf4)
   05161 Hepatitis B
    109693025 (Atf4)
   05163 Human cytomegalovirus infection
    109693025 (Atf4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109693025 (Atf4)
   05012 Parkinson disease
    109693025 (Atf4)
   05014 Amyotrophic lateral sclerosis
    109693025 (Atf4)
   05020 Prion disease
    109693025 (Atf4)
   05022 Pathways of neurodegeneration - multiple diseases
    109693025 (Atf4)
  09165 Substance dependence
   05030 Cocaine addiction
    109693025 (Atf4)
   05031 Amphetamine addiction
    109693025 (Atf4)
   05034 Alcoholism
    109693025 (Atf4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109693025 (Atf4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    109693025 (Atf4)
   04934 Cushing syndrome
    109693025 (Atf4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ccan03000]
    109693025 (Atf4)
Transcription factors [BR:ccan03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    109693025 (Atf4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF4407 Laminin_II Fez1 KIF21A Asd-4 DUF3450
Other DBs
NCBI-GeneID: 109693025
NCBI-ProteinID: XP_020029638
UniProt: A0A250YG23
LinkDB
Position
Unknown
AA seq 347 aa
MSEMSFLSSEVLAGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSGDKAKAGSSE
WLAVDGLVNASDTGKEDAFSGTDWMLEKMDLKEFDFDALFRLDDLETMPDELLATLDDTC
DLFTPVVQETNKEPPQTVNPIGHLPECLTKTDQVAPFTFLQPLPPGVLSSTPDHSFSLEL
GSEVDISEGDRKPDSTAYITMIPQCVKEEDNPSDNDSGICMSPESYPGSPQHSPSTSRGS
PNRSLPSAGVPRGSTRPKPYDPPGEIAKMKAEKLDKKLKKMEQNKTAATRYRQKKRAEQE
ALTGECKELEKKNEVLKEKADALAKEIQYLKDLIEEVRKARGKKKVP
NT seq 1044 nt   +upstreamnt  +downstreamnt
atgagcgagatgagcttcctgagcagcgaggtgttggcgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaagaaagcctaggcctcttagatgactacctggaggtg
gccaagcactttaaacctcatgggttctccggtgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcaatgcctcagataccggcaaggaggatgccttctcc
gggacagattggatgttggagaaaatggatctgaaggagtttgacttcgatgccctgttt
cgtttggatgacctagaaaccatgccagatgagctgttggccacgttggatgacacgtgt
gatctctttaccccagtagtccaagagactaacaaggagcccccccagacagtgaaccca
attggccatctcccagagtgtttaacaaaaaccgatcaggttgcccctttcaccttctta
caacctcttcccccaggggtcctctcttccactccagaccattcctttagtttagagtta
gggagtgaagtggatatctctgaaggagataggaagcccgactctactgcttacattacc
atgatcccccagtgtgtaaaggaggaagacaacccctcagataatgacagtggcatctgt
atgagcccggagtcatatccaggctctccccagcacagcccctccacctctagggggtct
ccaaataggagcttgccatctgcaggtgtcccccgtgggtctacccgccccaaaccttat
gatcctcctggagaaatagcaaaaatgaaggctgagaagctggataagaaactgaagaaa
atggagcagaacaagacagcagccaccaggtaccgtcagaaaaaaagggcagagcaggag
gccctcactggtgaatgtaaagagctagaaaagaagaatgaggttctgaaagagaaggca
gatgctctggccaaggagatccagtatctgaaagatttgatagaagaggtccgcaaagca
agggggaaaaagaaggtcccctaa

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