Castor canadensis (American beaver): 109693177
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Entry
109693177 CDS
T04791
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan04217
Necroptosis
ccan04380
Osteoclast differentiation
ccan04620
Toll-like receptor signaling pathway
ccan04621
NOD-like receptor signaling pathway
ccan04630
JAK-STAT signaling pathway
ccan04658
Th1 and Th2 cell differentiation
ccan04659
Th17 cell differentiation
ccan05145
Toxoplasmosis
ccan05160
Hepatitis C
ccan05161
Hepatitis B
ccan05162
Measles
ccan05164
Influenza A
ccan05165
Human papillomavirus infection
ccan05167
Kaposi sarcoma-associated herpesvirus infection
ccan05168
Herpes simplex virus 1 infection
ccan05169
Epstein-Barr virus infection
ccan05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
109693177 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
109693177 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
109693177 (Tyk2)
04621 NOD-like receptor signaling pathway
109693177 (Tyk2)
04658 Th1 and Th2 cell differentiation
109693177 (Tyk2)
04659 Th17 cell differentiation
109693177 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
109693177 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
109693177 (Tyk2)
05160 Hepatitis C
109693177 (Tyk2)
05171 Coronavirus disease - COVID-19
109693177 (Tyk2)
05164 Influenza A
109693177 (Tyk2)
05162 Measles
109693177 (Tyk2)
05168 Herpes simplex virus 1 infection
109693177 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
109693177 (Tyk2)
05169 Epstein-Barr virus infection
109693177 (Tyk2)
05165 Human papillomavirus infection
109693177 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
109693177 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccan01001
]
109693177 (Tyk2)
Enzymes [BR:
ccan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
109693177 (Tyk2)
Protein kinases [BR:
ccan01001
]
Non-receptor tyrosine kinases
JAK family [OT]
109693177 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
APH
FERM_C_FAK1
ABC1
Motif
Other DBs
NCBI-GeneID:
109693177
NCBI-ProteinID:
XP_020029898
UniProt:
A0A250YMD8
LinkDB
All DBs
Position
Unknown
AA seq
1180 aa
AA seq
DB search
MPLCQWKAMAKARKPSGVDAQPMASVGGLKVLLHWAGPDGGEPWVTFNEPSLTAEEICIR
IAHKVGITPPCFNLFALFDAHTQVWLPPNHILDVSRDTGLMLYFRMRFYFRNWHGMSLQE
PAVYRCGFPGTEPSSDRAEQGVQLLDSAAFEYLFEQGKHEFVNDVVSLWDLSSEEEIHHF
KNESLGMAFLHLCHLALCRGVPLEEVAREISFKNCIPRSFRQQIRQHNALTRLRLRTVFR
KFLRAFQPGQLSQQVVMVKYLATLERLAPRFGTERVPVCHLELLAQAEAEPCYIQDRGQG
PVDPSPESATGPPTHEVLVTGVGGIQWRPVQAEDSKGGSSSSRNPMPTLSRKKPKAHEEG
KQLVDRPREPPWTYFCDFQDISHVVLKECHVSIHLQDNQCLELSLPSRAMALSFVALLDG
YFRLTADSSHYLCHEVAPPRLVMSIQDGVHGPLLDPFVQAKLRTEDGLYLIHWSTSHPHR
LILSVAQRNLAPSTQSLRLRKFPITQQAGAFVLEGWGRSFASVQELRVALQGCSLRAGDD
CFSLRRCCLPRPGEISNLIIVRGSRTSTKPLNLSQLSFHRVHQDEITQLSHLGQGTRTNV
YEGLLRVGGPEEGQADSGAPEPAGGRVQELRVVLKVLDPSHHDIALAFYETASLMSQVSH
AHLAFVHGVCVRGSENIMVTEYVEHGPLDVWLRRERGHVLMTWKVAVAQQLASALSYLED
KNLVHGNVCGRNILLARPGLAEGTSPFIKLSDPGVGLGALSREERVEHIPWTAPECLPGG
NNSLSTAADKWGFGATLLEICFDGEAPLQGRGPSEKERFYQKQHQLPEPSCPELATLTSQ
CLTYEPAQRPSFRTILRDLTRLQPHNLVDVSAVNPDSPASDPTVFHKRYLKKIRDLGEGH
FGKVSLYCYDPTNDGTGEMVAVKALKAGCGPQLRSGWRREIDILRTLYHEHIVKYKGCCE
DQGEKSVQLVMEYVPLGSLRDYLPRHSVGLVQLLLFAQQICEGMAYLHAQRYIHRDLAAR
NVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDVWSF
GVTLYELLTHCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPDRCPSEVYLL
MKNCWEAEASFRPTFQNLIPILKMVHDKYQGQAPSVFSVC
NT seq
3543 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgtcagtggaaagccatggccaaggcccgcaagcccagtggggtggatgct
cagcccatggcctccgtgggaggcctgaaggtgcttctgcattgggctggccctgatggc
ggggagccctgggtcaccttcaacgagccctcactgactgccgaggagatctgcatccga
atcgcacacaaagtcgggatcacgccaccctgcttcaatctcttcgccctctttgatgcc
cacacccaagtatggctgcccccaaaccacatcctagatgtgtccagagacacaggcctg
atgctgtatttccgcatgaggttctatttccggaactggcacggcatgagtctccaggag
ccagctgtgtaccgctgtgggtttccggggaccgaaccatcctcagatcgggcagagcag
ggggtacagctcttggactcagctgcgtttgagtatctctttgagcagggcaagcatgag
tttgtgaatgatgtggtgtccctgtgggacctgtccagcgaggaagagatccaccatttt
aagaacgagagcctgggcatggcctttctccacctgtgccaccttgctctgtgccgcggt
gtccccctggaggaggtggccagggagatcagcttcaagaactgcatcccgcgctccttc
cgccagcagatccgccagcacaacgcgctgacccggctgcgcctgcgcactgtcttccgc
aagttcctgcgggctttccagccgggccagctgtctcagcaggtggtcatggtcaagtac
ctggccaccctcgagcgcctggcgccccgcttcggcactgaacgcgtacccgtgtgtcac
ctggagctactggcccaggctgaggcagagccctgctatatccaagacagagggcagggc
cctgtggaccccagccccgaatcggccaccgggccccccacccacgaggtgctggtgact
ggtgtcggtggcatccagtggcggccagtacaggctgaggattccaagggtggcagcagc
agcagcaggaaccccatgcccactctgtccaggaagaaacccaaggcccatgaggagggt
aagcagctggtggacaggcctcgggaaccaccgtggacctacttctgtgacttccaggac
atctctcacgtggtgctgaaagagtgccatgtcagtatccacctacaggacaaccagtgc
ctggagctgagcctgccttcccgtgctatggccctgtcctttgtggcactgctggatggc
tacttccgcttgaccgctgactctagccactacctgtgccacgaggtggcaccgccacgg
ctggtgatgagtatccaggatggtgtccatggacctctgctggatccgtttgtgcaggcc
aagctccgaactgaggatggcctctacctcatccactggagcaccagtcacccccaccgc
ctcatcctctcagtggcccagcggaacctggcacccagcacgcagagcttgcgcctcagg
aagttccccatcacgcagcaggccggggccttcgtgctggagggctggggccgctccttt
gccagcgtgcaggagctgcgggttgccttgcaaggctgctctctgcgggctggggacgac
tgcttctccctgcgccgctgctgcctgccccggccgggagaaatctccaaccttatcatc
gtgcgggggtctcggaccagcaccaagccactgaatctcagccagctcagcttccacagg
gtgcaccaggatgaaatcacccagctatcgcatttgggccagggtacaaggaccaatgtg
tatgagggtctcctgcgagtagggggccctgaggaaggacaagcagacagcggggcccca
gaacctgctgggggccgtgtgcaggagctacgtgtggtgcttaaagtactggatcccagt
caccacgacatcgccctggccttctacgaaacagccagcctcatgagccaggtctcccac
gcgcacctggccttcgtgcatggcgtctgtgtgcgcggctctgagaatatcatggtgaca
gagtatgtggagcacgggcccctggatgtgtggctgcggcgagagagaggccatgtgctc
atgacgtggaaggtagcagtggcccaacagctggccagtgccctcagctacctggaggat
aagaacctggttcatggtaacgtgtgtggccgtaacatcctgctggctcgcccggggctg
gcggagggcaccagcccatttatcaagctgagtgaccctggcgtgggtctgggcgccctc
tccagggaagagcgggtggaacacatcccctggacggctcctgagtgcctgcctggtggg
aacaacagcctgagcaccgctgctgataagtggggctttggcgccaccctccttgaaatc
tgctttgatggggaggcccctctgcagggccgtggcccctctgagaaagagcgtttctac
cagaagcagcaccagctgcctgagccctcctgccctgagctggccacactcaccagccag
tgcctgacctatgagcccgcccagcggccatccttccgcaccatcctgcgcgacctcact
cggctgcagccccacaatctcgtggatgtctctgctgtgaacccggactcacctgcctca
gaccccacggttttccacaagcgttatttgaaaaagatccgggatctgggcgagggtcac
tttggcaaggtcagcctgtactgctacgacccgaccaacgatggcaccggcgagatggtg
gcggtgaaagccctgaaggcgggttgcggcccccagctccgctcgggctggaggcgggag
atcgatatcctgcgcacgctgtaccacgagcatatagtcaagtacaagggctgctgcgag
gaccaaggcgagaagtcggtacagctcgtcatggagtacgtgcctctgggtagcctcaga
gactacttgccgaggcacagcgtcgggctggtccagctgctgctgttcgcccagcagatc
tgcgagggcatggcctacctgcacgcacagcgctacatccaccgagatctagctgcacgc
aacgtgctactggacaacgacaggctggtcaagatcggggactttggactagccaaggcc
gtgcctgaaggccacgagtactaccgtgtgcgcgaggacggagacagccctgtgttctgg
tatgccccagagtgcctgaaagagtgtaagttctactatgcatctgatgtctggtctttt
ggggtaaccctctatgagctcctgacacactgtgactccagccagagccccccttcgaaa
ttcatcgagctcataggcctcacccagggccagatgacggtgctgaggctcactgagttg
ctggaacgaggagagaggctcccccgaccggacaggtgtcccagtgaggtttatcttctc
atgaagaactgttgggaggcagaggcctccttccgccctaccttccagaacctcataccc
atcctcaagatggttcacgacaagtaccaaggccaggccccctcagtgttcagcgtgtgc
tga
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integrated database retrieval system
