Castor canadensis (American beaver): 109694415
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Entry
109694415 CDS
T04791
Symbol
Top2a
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
109694415 (Top2a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ccan03032
]
109694415 (Top2a)
03036 Chromosome and associated proteins [BR:
ccan03036
]
109694415 (Top2a)
Enzymes [BR:
ccan01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
109694415 (Top2a)
DNA replication proteins [BR:
ccan03032
]
Eukaryotic type
DNA Topoisomerases
109694415 (Top2a)
Chromosome and associated proteins [BR:
ccan03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
109694415 (Top2a)
Centrosome formation proteins
Centriole proteins
109694415 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
109694415
NCBI-ProteinID:
XP_020031911
UniProt:
A0A8B7VIT3
LinkDB
All DBs
Position
Unknown
AA seq
1529 aa
AA seq
DB search
MEVSPLQPVSENMQVNKKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQM
WVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN
GKGIPVVEHKVEKMFVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET
ASREYKKMFKQTWMDNMGRAGEMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMVR
RAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCL
TMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMW
IFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQV
QLNKKCSAVKHNRIKGIPKLDDANDAGSRNSTECTLILTEGDSAKTLAVSGLGVVGRDKY
GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD
QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSS
TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPDDDAAISLAFSKKQIDDR
KEWLTNFMEDRRQRKLLGLPEDYLYGQATTYLTYNDFINKELILFSNSDNERSIPSMVDG
LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL
NLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEWY
IPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIEE
LALNQYVINGEVAILNSTTIEISELPVRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYH
TDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTALDILRD
FFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRG
YDSDPVKAWKEAQQKVPDEEENEESDNDNEKSDSVTDSGPTFNYLLDMPLWYLTKEKKDE
LCKQRKEKEQELDTLKKKSPSDLWKEDLAAFIEELEVVEAKEKQDEQVVLSGKGGKAKGK
KTQMAEVLPSPQGKRVIPQVTVEMKAEAEKKIKKKIKSESTEGTPKEDDIELEGLKQRLE
KKQKKEPDTKAKKQTTLPFKPIKKGKKRNPWSDSESDMSSTESNFDVPPREIEPRRAATK
TKFTVDLDSDEDFSDFDEKNEDEDFVPSDASPPKTKAPPKHTKKELKPQKSVMSVDLEAG
DSENSVPPSTSPPAANFSTETEIINLPSKNNVTAKKTATKSQSSTSTAGTKRKVAPKKTK
ADPALNSDISQKPDPAKTKNRRKRKPSTSDDSDSNFEKVISKGATSKKPKEESYDFHVDM
DSAVAPRAKSVRAKKPITYLEESDEDDLF
NT seq
4590 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcctgtaagtgaaaatatgcaagtgaacaaaaagaaaaat
gaagatgctaagaaaagactgtctgttgaaagaatctatcaaaagaaaacgcaattggaa
cacatcttgctccgcccagacacctacattggctctgtggaattagtgacccagcaaatg
tgggtttacgatgaagatattggcattaactatagggaagtcacttttgttcctggtttg
tacaaaatctttgatgaaattctagttaatgctgcagacaacaaacaaagggatccaaaa
atgtcttgtattagagtcacgattgacccagaaaacaatttaattagtatatggaataat
ggaaaaggaattcctgttgttgaacacaaagttgagaagatgtttgtcccagctctcatc
tttggacaactcttaacttctagtaactatgacgatgatgaaaagaaagtgacaggtggt
cgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaaaca
gcaagtagagaatataagaaaatgttcaaacagacatggatggataacatggggagagct
ggtgagatggaactcaagccctttagtggagaagattatacatgtatcaccttccagcct
gatttatctaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggttaga
agagcatatgatattgctggatccactaaagatgtcaaagtctttcttaatggaaataag
ctgcccgtgaaaggattccgtagttatgtggatatgtatttgaaggataaattagatgaa
actggcaacccattgaaagtaatacatgagcaagtaaaccacagatgggaagtgtgttta
acaatgagtgaaaaaggctttcagcaaattagttttgtcaacagcattgctacttccaag
ggtggtagacatgttgattatgtagctgatcagattgtgagtaaacttgttgatgtagtg
aagaagaagaacaagggtggtgttgcagtgaaagcacatcaggtgaaaaatcacatgtgg
atttttgtgaatgccttaattgaaaacccaacatttgactctcagacaaaagaaaatatg
actttacaagccaagagctttgggtcaacatgtcaattaagtgaaaaattcatcaaagct
gcaattggctgtggtattgtagaaagcatactaaactgggtgaagtttaaggcccaagtc
cagttaaacaagaagtgttctgctgtaaaacataatagaatcaagggaattcccaaacta
gatgatgccaatgatgcaggaagccgaaactccaccgagtgtacacttatcctgactgag
ggagactcagccaagactttggctgtttcaggccttggtgtagttgggagagacaaatat
ggggttttccctcttagaggaaagatactcaatgtccgagaagcttctcataagcagata
atggaaaatgcagaaattaacaacatcattaagattgtgggtcttcagtacaagaaaaac
tatgaagatgaagattcattgaagactcttcgttacgggaagataatgattatgacagat
caggaccaagacggttctcatatcaaaggcttgctgattaattttatccatcacaactgg
ccctctcttctgcgacatcgttttctagaggaatttatcactcccattgtaaaggtatct
aaaaacaagcaagaaatggcattctatagccttcctgaatttgaagaatggaagagttct
actccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggcaccagcacatca
aaggaagctaaggagtactttgcagatatgaaaagacatcgtatccaattcaaatattct
gggcctgacgatgatgctgcaatcagtctggcctttagcaaaaaacagatagatgatcga
aaggaatggttaactaatttcatggaggacagaagacaacggaagttacttggccttcct
gaggattatttatatggacaagctaccacctacctgacgtacaatgacttcataaacaag
gaacttatccttttctcaaattctgataatgagagatctatcccatctatggtagatggt
ttgaaaccaggtcagagaaaagttttgtttacttgtttcaaaagaaatgataagcgagaa
gtaaaggttgcccaattagctggatcagtggcagaaatgtcatcttatcatcatggtgag
atgtcactaatgatgaccatcatcaatttggctcagaattttgtggggagcaataatctg
aacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattctgct
agtcctcgatacatctttacaatgctcagccctttggctcggttgttatttccaccaaaa
gatgatcacacattaaagttcttatatgacgacaaccaacgtgttgagcctgaatggtac
attcctattatacccatggtgctaataaatggtgctgaaggaattggaactgggtggtcc
tgcaaaattcccaactttgatgttcgtgaagttgtaaataacattaggcgtttgatggat
ggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtacaattgaagag
ctggctttaaatcagtatgtgattaatggtgaagtagctattcttaactccacaaccatt
gaaatctcagaacttcccgtcagaacatggactcagacatacaaagaacaggttctagaa
cccatgttgaatggcactgagaagacaccccctctcataacagactatagggaataccat
acagataccacagtgaagtttgttgtgaagatgactgaagaaaaattagcagaggcagaa
agagttggattacacaaagtcttcaaactccaaactagtctcacctgcaactctatggtg
ctttttgaccatgtaggctgtttaaagaaatatgacacagcattggatattctcagagac
ttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatgctt
ggtgcagaatcagctaaactgaacaatcaggctcgctttatcttagagaaaatagatggc
aaaattatcattgaaaacaagcctaagaaagaattaattaaagttctgattcagagggga
tatgattcagatcctgtgaaagcctggaaagaagcccagcaaaaggttccagacgaagaa
gaaaatgaagaaagtgacaatgacaatgaaaaaagtgactctgtaacagattctgggcca
accttcaactatcttcttgatatgcccctttggtatctaaccaaggaaaagaaagatgaa
ctgtgtaaacaaagaaaggaaaaggagcaagagttggacacattaaagaaaaagagccca
tcagatttgtggaaagaagacttagctgcttttattgaagaactggaggttgttgaagcc
aaggaaaaacaagatgaacaagtagtactttctgggaaagggggaaaagcaaagggaaaa
aaaacacagatggctgaggttttgccttctccacaaggaaaaagagtcattcctcaagtg
actgtagagatgaaagcagaagcagaaaagaaaattaaaaagaaaattaagagcgaaagt
acggagggaacacctaaggaagatgatatagaactagaaggcctaaaacaaagattagag
aagaaacagaaaaaagaaccagataccaaggcaaagaaacaaactacgttgccatttaaa
cctatcaaaaagggaaagaagagaaacccctggtctgattctgaatcagatatgagcagt
actgaaagtaattttgatgtccctccacgagaaatagagccacggagagctgcaacaaaa
actaagttcacagtggatttggattcagatgaggatttctcagattttgatgaaaaaaat
gaagatgaagattttgttccatcagatgctagtccacctaagaccaaagctccaccaaaa
catactaaaaaagaactgaagcctcagaaaagtgtcatgtcagttgaccttgaagcaggt
gattctgagaacagtgtaccaccttctacaagccctccagctgctaatttctcaactgaa
actgaaattataaacctaccttccaaaaataacgtgacagcaaaaaagacagcaacaaaa
agtcagtcttctacctctactgctggtaccaaaagaaaggtcgcaccaaaaaaaaccaaa
gcagatccagccttaaattctgatatctctcaaaagcctgatcctgccaaaaccaagaat
cggcgcaaaaggaagccatccacttctgatgattctgactctaattttgagaaagtcatt
tctaaaggcgccacaagcaagaaacccaaggaggagagctatgatttccatgtggacatg
gactcagccgtagctccgcgggcaaagtctgtacgagcaaagaaacctataacgtacctt
gaagagtcagatgaagatgatctgttttaa
DBGET
integrated database retrieval system
