KEGG   Castor canadensis (American beaver): 109694743
Entry
109694743         CDS       T04791                                 
Symbol
Pld1
Name
(RefSeq) phospholipase D1
  KO
K01115  phospholipase D1/2 [EC:3.1.4.4]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan00564  Glycerophospholipid metabolism
ccan00565  Ether lipid metabolism
ccan01100  Metabolic pathways
ccan04014  Ras signaling pathway
ccan04024  cAMP signaling pathway
ccan04071  Sphingolipid signaling pathway
ccan04072  Phospholipase D signaling pathway
ccan04144  Endocytosis
ccan04666  Fc gamma R-mediated phagocytosis
ccan04724  Glutamatergic synapse
ccan04912  GnRH signaling pathway
ccan04928  Parathyroid hormone synthesis, secretion and action
ccan05200  Pathways in cancer
ccan05208  Chemical carcinogenesis - reactive oxygen species
ccan05212  Pancreatic cancer
ccan05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    109694743 (Pld1)
   00565 Ether lipid metabolism
    109694743 (Pld1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    109694743 (Pld1)
   04072 Phospholipase D signaling pathway
    109694743 (Pld1)
   04071 Sphingolipid signaling pathway
    109694743 (Pld1)
   04024 cAMP signaling pathway
    109694743 (Pld1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    109694743 (Pld1)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    109694743 (Pld1)
  09152 Endocrine system
   04912 GnRH signaling pathway
    109694743 (Pld1)
   04928 Parathyroid hormone synthesis, secretion and action
    109694743 (Pld1)
  09156 Nervous system
   04724 Glutamatergic synapse
    109694743 (Pld1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109694743 (Pld1)
   05208 Chemical carcinogenesis - reactive oxygen species
    109694743 (Pld1)
   05231 Choline metabolism in cancer
    109694743 (Pld1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    109694743 (Pld1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccan04131]
    109694743 (Pld1)
Enzymes [BR:ccan01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.4  phospholipase D
     109694743 (Pld1)
Membrane trafficking [BR:ccan04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    109694743 (Pld1)
 Endosome - Golgi transport
  Others
   Others
    109694743 (Pld1)
SSDB
Motif
Pfam: PX PLDc PH PLDc_2 DUF3785
Other DBs
NCBI-GeneID: 109694743
NCBI-ProteinID: XP_020032464
UniProt: A0A8B7VMU0
LinkDB
Position
Unknown
AA seq 1005 aa
MSLQKEPRVNTSALQKIAADMSNLIENLDTRELHFEGEEVECDVSPSDPKTQEVCIPFSA
IYNTQGFKEPNIQTYLSGCPIKAQVLEVERFTTRVPSINLYTIELTHGEFKWQVKRKFKH
FQEFHRELLKYKAFIRIPIPTRRHTFRRQNVKGEEPQEMPSLPRSSENRIREEQFFGRRK
QLEDYLTKILKMPMYRNYHATTEFLDISQLSFIRDLGPKGLEGMIMKRSGGHRVPGLNCC
GQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFRIKVGKKETETKYGLRIDN
LSRTLILKCNSYRHARWWGGAIEEFIQKHGTNFLKDHRFGSYAAIQEDTLAKWYVNAKGY
FEDVANAIEEAEEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQQGVRIFVMLYK
EVELALGINSEYSKKTLMRLHPNIKVMRHPDHVSSSVYLWAHHEKLVIIDQSIAFVGGID
LAYGRWDDNEHRLTDVGSVKRITSGPSLGSLTAAMTESMESLSLRGKNEPIKDGPVLKNV
NDADSKLKGIGKPRKFSKFSLYRQLYKHHLHNTDSISSVDSASNTGSIRSLQTGVGELHG
ETRFWHGKDYCNFVFKDWVQLDKPFADFIDRYSTPRMPWHDISSVVHGKAARDVARHFIQ
RWNFTKIMKPKYRSLSYPFLLPKSQTTAHELRYQVPGAVRATVQLLRSAADWSAGIKYHE
ESIHSAYIHVIENSKHYIYIENQFFISCADDKVVFNKVGDAIAQRILKAHREGQRYRAYI
IIPLLPGFEGDISTGGGNALQAIMHFNYRTMCRGENSILGQLKPMLGNQWINYISFCGLR
THAELEGNLVTELIYVHSKLLIADDNTVIIEITWSANFFVSVTQLGGYLYFRVVLGYISD
PSEDIQDPVSDKFFKEVWVSTAARNATIYDKVFRCLPNDEVHNLMQLRDFITKPILARED
PIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPMEVWT
NT seq 3018 nt   +upstreamnt  +downstreamnt
atgtctctgcaaaaggagcccagagtaaacacctctgcactgcagaaaatcgctgctgac
atgagcaatttgattgaaaatctagacacgcgggagctccatttcgagggagaggaggta
gaatgtgatgtgtctcccagtgaccccaagactcaggaagtgtgtatccctttctccgct
atttataacactcaaggatttaaggagcctaacattcagacgtatctctccggctgtcca
ataaaagcacaagtcctggaagtggagcgcttcacaacaagggtaccaagtatcaacttg
tacactattgaattaacacatggggagtttaagtggcaagttaagaggaaatttaagcac
tttcaagaatttcacagagagctgctcaagtacaaagcctttatccgaatccccattccc
accagaagacacacattcaggagacaaaatgtcaaaggggaggagccccaagagatgccc
agtttgccccggtcatctgaaaacaggattcgggaagaacagttctttggcagaaggaaa
caactggaagattacttgacaaaaatactaaaaatgcccatgtatagaaactatcatgcc
acaacagaattccttgatataagccagctgtctttcatccgagatttgggaccaaagggc
ctagaaggtatgatcatgaaaagatctgggggacacagagtaccaggcttgaattgctgt
ggtcagggaagagcctgctaccggtggtcaaaaaggtggctaattgtgaaagattccttt
ttactgtacatgaagccagacagcggtgccattgcctttgtcctgctggtagataaagaa
ttcagaattaaggtggggaagaaagagacagagacgaaatacggtcttcgaattgataat
ctttcaaggacacttattttaaaatgcaacagttacagacatgctcggtggtggggaggg
gctatagaagaattcatccagaaacacggcaccaacttcctcaaagatcaccgatttgga
tcctatgctgctatccaggaggacactctggctaagtggtatgttaatgccaaaggatat
tttgaagacgtggcgaatgccatagaagaggcagaagaagagattttcatcacagattgg
tggttaagtccagagatcttcctgaaacgcccagtggttgaaggaaatcgttggcggttg
gactgcattcttaaacgaaaagcacagcagggtgtgcgtatcttcgtcatgctatacaag
gaggtggagctcgcactggggatcaacagtgagtacagcaagaagacactgatgcggctg
caccccaacataaaggtgatgaggcacccggatcatgtgtcatccagcgtctacctgtgg
gctcatcacgagaaacttgtcatcatagatcagtcaatagccttcgtgggtggcattgac
ctggcctacgggagatgggacgacaatgagcacaggctcacagacgtgggcagtgtgaag
aggatcacctcagggccgtctctgggctctctcacagctgcaatgacagagtctatggaa
tccttaagcctcagaggtaaaaacgaacccattaaagatgggcctgtcctgaagaatgtg
aatgatgctgattccaaactgaaaggaatcggaaagcccagaaagttctccaaatttagc
ctctaccgacagctgtacaaacatcacctgcacaacacagacagcatcagcagcgtcgac
agcgcctccaacaccggctccatccgcagcttacagacaggtgtgggggagctgcatggg
gagacccggttctggcacggaaaggactactgcaattttgtcttcaaagactgggttcag
ctggacaagccttttgctgatttcattgacaggtactccactccccggatgccctggcat
gatattagctctgtggtccacgggaaggcggctcgcgatgttgcaagacacttcatccaa
cgctggaacttcacaaagattatgaaaccaaaataccggtccctttcttatccttttctg
cttccgaagtctcaaaccacagcccatgagctgaggtaccaggtgcctggggctgtccgc
gccactgtgcagttgctccgctctgctgctgattggtctgctggtataaagtaccatgaa
gagtccatccactctgcttacatccatgtgatagagaacagcaagcactacatctatatt
gaaaaccaatttttcataagctgtgctgatgacaaagtcgtgttcaacaaggtgggcgat
gccattgcccagaggatcctgaaggctcacagggaaggccagagataccgggcatacatt
ataataccacttttgccaggctttgaaggagacatttccacgggtggaggaaacgctctg
caggcaataatgcacttcaactacagaactatgtgcagaggagaaaattccatccttgga
cagttaaaaccaatgcttggtaatcagtggataaactacatttcattctgtggtcttaga
acacacgcagagctagaaggaaatctagtcactgaacttatctatgtccacagcaagctg
ctaattgctgatgataacactgtcattattgaaataacatggtcagcaaacttctttgtc
tcagttactcaacttggaggttacttatatttcagagttgtccttggctatatttctgac
ccaagtgaggacattcaggatccagtgagtgacaaattcttcaaggaggtgtgggtctca
acagcagctcgaaatgctacaatttatgataaggtgttccggtgccttcctaatgacgaa
gtacacaatttaatgcaactgagagactttataaccaagcctatcttagcaagggaagat
cccattagagctgaggaagaactaaaaaagatccgtgggttcttggtgcaatttcccttt
tatttcctttctgaagaaagcctgctgccttctgttggaaccaaagaagccatagtgccc
atggaggtttggacttag

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