Castor canadensis (American beaver): 109695445
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Entry
109695445 CDS
T04791
Symbol
Pde3b
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase B
KO
K13296
cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:
3.1.4.17
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan00230
Purine metabolism
ccan01100
Metabolic pathways
ccan04022
cGMP-PKG signaling pathway
ccan04024
cAMP signaling pathway
ccan04371
Apelin signaling pathway
ccan04910
Insulin signaling pathway
ccan04914
Progesterone-mediated oocyte maturation
ccan04922
Glucagon signaling pathway
ccan04923
Regulation of lipolysis in adipocytes
ccan04924
Renin secretion
ccan05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
109695445 (Pde3b)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
109695445 (Pde3b)
04024 cAMP signaling pathway
109695445 (Pde3b)
04022 cGMP-PKG signaling pathway
109695445 (Pde3b)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
109695445 (Pde3b)
04922 Glucagon signaling pathway
109695445 (Pde3b)
04923 Regulation of lipolysis in adipocytes
109695445 (Pde3b)
04914 Progesterone-mediated oocyte maturation
109695445 (Pde3b)
04924 Renin secretion
109695445 (Pde3b)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
109695445 (Pde3b)
Enzymes [BR:
ccan01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
109695445 (Pde3b)
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Paralog
GFIT
Motif
Pfam:
PDEase_I
Motif
Other DBs
NCBI-GeneID:
109695445
NCBI-ProteinID:
XP_020033573
UniProt:
A0A8B7VPL3
LinkDB
All DBs
Position
Unknown
AA seq
1125 aa
AA seq
DB search
MKRDERDVKAMRSPQAPDGVGSPPESVRNGYVKSCVSPLRQDPPRGFFFHLCRLCNVEPP
SPSRPQPRRGSPSAGARLSLGALAAFVLALLLLLLLLLGAGPESWASGVAGLRTLLSVCS
YSLSPLFSIACAFFFLTCFLTRTQRGSSPGPGPGPGPGPGGGSWWLLALPACCYLGDLLA
WPCWAWPWGTAAPHPIPAPAPASRLVLVLSCVGLLTFARPGTLRHRIVVLPFASCVWWVS
FASLGALPAFLRPLLSCLVGATGCLLALGLDHFFHIREASPHPRCWASGAEDKVPVIRPR
RRSSCVSLGETAAASHGGSGKVFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGV
DLSVLNEARNMVSDLLIDPSLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCS
EIEDPAEKGDRKLPKGLSSRNSLPTPQLRRSSGTSGLLPTEQSSRWERSNGRRPHQEFGI
PSQGYYLNGPFSSNLLAMPKQRSSSISLSHHVGLRRAGALSSLSPVNSPSHGPLSPGSLT
NRSPVEFPDTADFLTKPSVVLHRSLGNAPSTPDFYQYLRNSDSNLCNSCGRQILKYISTC
ESDGTDHHGGKSGEEDSTIFSKESFNLMETQPEEEAENRVCRKLPLEGDNHLTEEAQQPN
IGQEALLDLMLVEDYDSLIEKMSNWNFQIFELVEKMGAKSGRILSQVMYTLFQDTGLLEI
FKIPTQEFMNYFHALENGYRDIPYHNRIHATDVLHAVWYLTTRPIPGLQQIHNDHETGNE
TDSDVRLTPGQIAYISSKSCSIPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAF
LVATNAPQAVLYNDRSVLENHHAASAWNLYLSRSEYNFLLNLDHVEFKRFRFLVIEAILA
TDLKKHFDFLAEFNAKANDVNSNGIEWNNENDRLLVCQVCIKLADINGPAKVRDLHLKWT
EGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQ
WLEAEEDDDTESGDDEDGEELDTDHEEMEDNLNPKPQRRKGRRRIFCQLMHHLTENHKIW
KEIIEEEEKCKAEGNKLQVENTSLPQADEIQVIEEADEEEERQFE
NT seq
3378 nt
NT seq
+upstream
nt +downstream
nt
atgaagagggacgagcgagacgttaaagccatgaggtccccccaggcgccggacggggtc
ggctcgccccccgagagtgtgcggaatggctacgtgaagagctgtgtgagccccttgcgg
caggaccctccgcgcggcttcttcttccacctctgccgcctctgcaacgtggagccgccg
tcgccctcccgcccgcagccgcggcgcggctccccctccgccggggcgcgcctctcgctg
ggcgccctggccgcctttgtcctcgcgttgctgctgctgctgctgctgctgctgggcgcg
gggcccgagagctgggcgtccggggtcgccgggctgcgcacgctgctgagcgtgtgctcg
tacagccttagtcccctcttcagcatcgcctgtgccttcttcttcctcacctgcttcctg
acccggacccagcgggggtccagtcccggtcccggccccggccccggccctggcccgggc
ggcggctcctggtggctgctggcgctgcccgcttgctgttacctgggggacttgttggcg
tggccatgctgggcttggccgtgggggaccgcggccccgcaccccatcccggccccggcg
cccgcgagcaggctggtcctggtgctgagctgcgtgggtctgctgacattcgcgcgcccc
gggacgctccggcaccgcatcgtggtgctgcccttcgccagctgcgtctggtgggtgtcc
ttcgccagcctcggggcgctacccgccttcctgcggccgctgctgtcctgcctggtcggg
gccaccggctgcctgctggccctgggcttggatcacttctttcacatcagggaagcctcg
ccgcatccccgctgttgggccagtggcgcggaagacaaagtgcctgtgatccgaccccgc
aggaggtccagctgcgtgtcgctgggagagaccgcggctgcctcccatggtggcagtggc
aaagtattccggagaccctcgctgccctgcatctccagggagcagatgattctttgggat
tgggatttaaagcagtggtacaaacctcattaccagaattctggaggtggaaatggagtt
gatctttcagtgctaaatgaggctcgcaatatggtgtcagatcttctgattgacccaagc
cttcccccacaagtcatttcttccctacggagtatcagtagcttgatgggtgctttctca
ggttcctgtaggccgaagattaatcctcttacaccatttcctggattttacccctgctct
gaaatagaggatccagctgagaaaggagatcgaaaacttcccaagggactaagtagtagg
aatagtttgccaactccacagttgaggaggagctcaggaacttcaggattgctacctact
gaacagtcttcaaggtgggaacgcagtaatggcagaaggcctcaccaagaatttgggatt
ccaagtcaaggatactatctaaatgggccttttagttcaaatctcctggcaatgccgaag
caaaggtcatcatctatatcactgtctcaccatgtaggtctcagaagagctggtgcttta
tccagcctgagtcctgtgaattctcccagccatgggccactgtctcctggctctctaact
aatcggtcacccgtagaatttcctgatactgctgattttcttactaagccaagtgttgtt
ttacatagatctctgggaaatgcacccagtacaccagatttttatcagtaccttagaaat
tctgatagcaatctgtgtaacagctgtggacgtcaaatactaaaatacatttcaacatgt
gaatctgatggtacagaccaccacggtggaaaatcaggtgaggaagacagcaccattttc
tcaaaagaatcattcaaccttatggaaactcaaccagaagaggaagcagagaacagagtc
tgcagaaaattacctttggaaggtgataatcacctaacagaagaggcacagcaaccaaat
attggacaggaagcattactggaccttatgttagtagaagattatgactcattaatagaa
aagatgagcaactggaattttcaaatttttgagcttgtagaaaaaatgggagcaaaatca
ggaaggattctcagtcaggttatgtataccttatttcaagacactggtttattggaaata
tttaaaatccccactcaagaatttatgaactattttcatgcattagaaaatggctatcga
gacattccatatcacaatcgtatacatgccacagatgtcctacatgcagtttggtatctg
acaacacggccaattccaggcttacaacagatccacaatgatcatgaaacaggaaatgaa
acagattctgatgttagacttactcctgggcaaattgcttatatttcttcgaagagctgc
tctatcccagatgagagttatggctgcctgtcttcaaacattccagcattagaattgatg
gctttgtatgtggcagctgccatgcatgattatgatcacccagggaggactaatgcattt
ctagtggctacaaatgcacctcaggcagttttgtacaatgacagatctgttctggaaaat
catcatgctgcatcagcttggaatctgtatctttctcgctcagaatacaactttcttctt
aatcttgatcatgtggaattcaagcgttttcgttttttagtcattgaagcaatccttgcc
acagatcttaaaaagcattttgatttccttgctgaatttaatgccaaggccaatgatgta
aatagtaatggcatagaatggaataatgaaaatgatcgcctcttagtctgccaagtgtgc
atcaaattagcagacataaatggcccagcaaaagttcgggacttgcatttgaaatggaca
gaagggatcgtcaatgaattttatgaacagggagatgaagaagcaaatcttggcctacca
atcagtccctttatggatcgttcttctcctcaactagcaaaactccaagaatcttttatc
acccacattgtgggtcccctgtgtaactcctacgatgctgctggtttgctgccgggtcag
tggctagaagcggaagaggatgatgatactgaaagtggtgatgatgaagatggtgaagaa
ttagatacagatcatgaagaaatggaagacaatctaaatcctaaaccacaaagaaggaaa
ggcagacggcgaatattttgtcagctaatgcaccacctcactgaaaaccacaagatatgg
aaggaaatcatagaggaagaagaaaaatgtaaagccgaggggaataaactgcaggtggag
aatacctccttacctcaagcagatgagattcaggtcattgaagaagcagatgaagaggaa
gagcgacagtttgaataa
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