Castor canadensis (American beaver): 109695994 Help Entry 109695994         CDS       T04791                                  Symbol Itgb4 Name (RefSeq) integrin beta-4 isoform X1   KO K06525   integrin beta 4 Organism ccan  Castor canadensis (American beaver) Pathway ccan04151   PI3K-Akt signaling pathway ccan04382   Cornified envelope formation ccan04510   Focal adhesion ccan04512   ECM-receptor interaction ccan04810   Regulation of actin cytoskeleton ccan04820   Cytoskeleton in muscle cells ccan05165   Human papillomavirus infection ccan05410   Hypertrophic cardiomyopathy ccan05412   Arrhythmogenic right ventricular cardiomyopathy ccan05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     109695994 (Itgb4)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     109695994 (Itgb4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     109695994 (Itgb4)   09142 Cell motility    04820 Cytoskeleton in muscle cells     109695994 (Itgb4)    04810 Regulation of actin cytoskeleton     109695994 (Itgb4)  09150 Organismal Systems   09158 Development and regeneration    04382 Cornified envelope formation     109695994 (Itgb4)  09160 Human Diseases   09172 Infectious disease: viral    05165 Human papillomavirus infection     109695994 (Itgb4)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     109695994 (Itgb4)    05412 Arrhythmogenic right ventricular cardiomyopathy     109695994 (Itgb4)    05414 Dilated cardiomyopathy     109695994 (Itgb4)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ccan04147]     109695994 (Itgb4)    04515 Cell adhesion molecules [BR:ccan04515]     109695994 (Itgb4)    04090 CD molecules [BR:ccan04090]     109695994 (Itgb4) Exosome [BR:ccan04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    109695994 (Itgb4)   Exosomal proteins of bladder cancer cells    109695994 (Itgb4) Cell adhesion molecules [BR:ccan04515]  Integrins   Integrin beta subunits    109695994 (Itgb4) CD molecules [BR:ccan04090]  Proteins   109695994 (Itgb4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Integrin_beta fn3 Calx-beta Integrin_B_tail Pur_ac_phosph_N EGF_Teneurin I-EGF_1 PSI_integrin Ig_DSCAM-DSCAML_C EGF_integrin EGF_2 EGF_TEN vWA_SIBA-E DUF3805 Motif Other DBs NCBI-GeneID:  109695994 NCBI-ProteinID:  XP_020034402 UniProt:  A0A8B7VS04 LinkDB All DBs Position Unknown AA seq 1870 aa AA seqDB search MAGLCPNLWARLLLAGLLSFSLPGNMANRCKKAQAESCTECIRVDKDCAYCADELFKERR CNTQVELLAAGCRREYVVVMESSFKITEETQIDTTLRRSQVYPQRLQVRLRPGEERHFEF EVFEPLESPVDLYILMDFSNSMSDDLDNLKQMGQNLAKILSQLTSDYTIGFGKFVDKVSV PQTDMRPEKLKEPWPNSDPPFSFKNVISLTDDVKEFWDKLQGERISGNLDAPEGGFDAIL QTAVCTRDIGWRPDSTHLLVFSTESAFHYEADGANVLAGIMNRNDEKCHLDGKGAYTQYK TQDYPSVPTLVRLLAKHNIIPIFAVTNYSYSYYEKLHTYFPVSSLGVLQEDSSNIVDLLE EAFYRIRSNLDIRALDSPRSLRTEVTSKMFQKTKTGSFHIRRGEVGTYDVQLRAVEDVDG THVCQLAEDDQKGNIHLKPSFSDGLQIDVGIICDVCACELQKEVRSARCHYRGDFMCGHC VCNEGWSGKTCNCSTGSLSDTQPCLREGEELPCSGHGECQCGRCVCYGEGRYEGHFCEYD NFQCPRTSGFLCNDRGRCSMGQCVCEPGWTGASCDCPLSNATCIDSNGGICNGRGYCECG RCHCDQQSLYTDTTCEINYSAIRLGLCEDLRSCVQCQAWGTGEKKGRSCQECSFKVKMVD ELKKAEEVVESCSFRDEDDDCTYSYTVEGDGSPGPNSTVLVHRKKDCPPNSFWWLIPLLI FLLLLLALLLLLCWKYCACCKACLALLPCCNRGHMVGFKEDHYMLRENLMASDHLDTPML RSGNLKGRDMVRWKITNNVQRPGFATHAASTNPTELVPYGLSLRLARLCTENLMKPGTRE CDQLRQEVEENLNEVYRQVTGAHKLQQTKFRQQPNAGKKQDHTIVDTVLMAPRSAKQTLL KLTEKQVEQGAFHELKVAPGYYTLTAEQDARGMVEFQEGVELVDVRVPLFIRPEDDDEKQ LLVEAIDVPVGTATLGRRLVNITIIKEQASGVVSFEQPEYLVSHGEQVARIPVVRRILDN GKSQVSYRTQDNTAQGNRDYVPMEGELLFHPGETWKELQVKLLELQEVDSLLRGRQIRRF HVQLSNPKFGARLGQPQSATVIIGEPDELDRNLVSQALSSLPPPRGDLDAPQNPNAKAAG SRKIHFNWLPPPGKPTGYRVKYWIQGDSESEAHLLDSKVPSVELTNLYPYCDYEMKVCAY GAQGEGPYSSLVSCRTHQEVPSEPGRLAFNVVSSTVTQLSWAEPAETNGEITAYEVCYGL VNEDNRPIGPMKKVLVDNPKNRMLLIENLRESQPYRYTVKARNGAGWGPEREAIINLATQ PKRPMSIPIIPDIPIVDAQGGEDYESFLMYSDDVLRSPAGSQRPSVSDDTGGGWKFEPLL GEELDLRSITWLLPPELIPRLSVSSGRSSDDSGTGGAAREGGGRARAATPRPPGEHLVNG RMDFAFPGSANSLHRMTAANVAYGTHLSPHLPHPMLSTSSTLTRDYHSLTRTEHSHSATL PRDRSTLTSLSSQGLPPIWEDGRSRLPLSWALGSWSRAQMKGLPNSRGSRDTIILAGQPA SPSWGPDFHMAVGVPDTPTRLVFSALGPTSLKVSWQEPQSERVLLGYSVEYQLLNGGELY RLNIPNPDQTSVVVEDLLPNHSYVFRVRAQSQEGWGREREGVITIESQVHPQSPLCPLPG SAFTLSTPSAPGPLVFTALSPDSLQLSWERPRRPNGDILGYLVTCEMAQGGGPATTFRVD GDNLESRLTVPGLSENVPYKFKVQARTTEGFGPEREGVITIESQDGGPFPQLGSHSGLFQ HPLQGEFSSITTTHTSTTEPFLVDGLTLGSQHLEASGSLTRHVTQEFVSRTLTTSGTLST QVSDQQFFQP NT seq 5613 nt NT seq  +upstreamnt  +downstreamnt atggcagggctgtgtcccaacctgtgggccaggctgctgttggcaggtctgctaagtttc agccttccagggaacatggccaaccgctgcaagaaggctcaggcggagagctgcaccgag tgcatccgtgtggacaaggactgtgcctattgtgcggatgagctgtttaaggagcggcgc tgcaacacgcaggtggagctgttggcggcaggctgccggcgggagtacgtggtggtcatg gagagcagcttcaaaatcacagaggaaacccagattgacaccactctgcgccgtagccaa gtgtacccacaacgcctgcaggtccggctgcggccgggggaggagcgtcactttgagttc gaggtgtttgagcctctggagagccccgtggatctgtatatcctcatggacttctccaac tccatgtctgatgacttggacaacctcaagcagatggggcagaacctggccaagatcctg agccagctcaccagtgactacacgatcgggtttggcaaatttgtggacaaagtcagtgtc cctcagacagacatgaggcctgagaagctgaaggaaccctggcccaacagtgaccccccc ttctccttcaagaacgtcatcagcctgacagatgatgtgaaggagttctgggataaactg cagggagagcggatctcaggcaatctggatgcacctgaaggcggctttgatgccattctt cagacagctgtgtgtacaagggacattggctggcgccctgacagcacccacctgctggtg ttctccactgagtctgccttccactatgaggctgatggcgccaatgtgctggctggcatc atgaaccgcaatgatgagaagtgtcacctggacggcaagggagcctacacccagtacaag acacaggactacccatcagtgcccacgctggtgcgcctgcttgccaagcacaacatcatc cccatcttcgctgtcaccaactactcctacagctactacgagaagctgcatacatatttc ccggtctcctcgctgggagtgctgcaggaggactcatccaacatcgtggacctgctagag gaggccttctatcgcattcgctccaacctggacatccgagccctggacagcccccgaagc ctgcggaccgaggtcacctccaagatgttccaaaagacaaagactggatccttccacatc aggcggggggaagtgggcacatacgacgtacaactgcgggctgtggaagatgtagacggg acacacgtgtgtcagctggcagaagatgatcagaaaggcaacatccacctaaagccctcc ttctccgacggcctccagatagacgtgggcatcatctgtgacgtgtgtgcttgtgaactg caaaaagaggtgcggtcagctcgctgccactatagaggagacttcatgtgcgggcactgt gtgtgcaatgagggctggagtggcaagacctgcaactgttccacgggctctctgagtgac acacagccctgccttcgggagggtgaggaattgccgtgctcaggccatggggaatgccag tgtgggcgctgtgtgtgctatggtgaaggccgctacgagggtcacttctgcgagtatgac aacttccagtgtccccgcacctccgggttcctctgcaatgataggggacgctgctccatg ggccagtgtgtgtgtgagcctggttggacaggtgccagctgtgactgtcccctcagcaat gccacctgcatcgatagcaatgggggcatctgtaatggacgtggctactgcgagtgtggc cgctgccactgcgaccagcagtcgctctacacagacaccacctgtgagatcaactactca gcgatccgcctgggcctctgtgaggacctgcgctcctgtgtgcagtgccaagcttggggc accggggagaagaaggggcgctcgtgccaggagtgcagcttcaaggtcaagatggtagat gagcttaagaaagctgaagaggtagtggagtcctgctccttccgggacgaggatgatgac tgcacctacagctacactgtggagggtgacggcagccctgggcccaacagcaccgttctg gtccacaggaaaaaggactgtcctcctaactccttctggtggctcatccccctgctcatc ttcctcctgctgctcttggcactgttgctgctgctttgctggaagtattgtgcctgctgc aaggcctgcctggcattgctcccttgctgtaaccgaggtcacatggtgggctttaaggaa gaccactacatgctgcgcgagaacctcatggcctcagaccacctggacacacccatgctg cgcagcgggaacctcaaggggcgtgacatggtccgctggaagatcaccaacaatgtgcag agacctggctttgccacccatgctgccagcaccaaccccacagagctggtgccctatggg ctgtccctgcgccttgcccgcctctgcacggagaacctgatgaagcctggcacccgagag tgtgaccagctgcgccaggaggtggaggagaatctgaacgaggtatacagacaggtcacc ggtgcacacaagctccagcaaacaaagttccggcaacagccaaacgccgggaaaaagcaa gaccacaccattgtggacacagtgctgatggcgccccgctcggccaaacagactctgcta aagctgacagagaagcaagtggagcagggggccttccacgagctcaaggtggctcctggc tactacactctcactgcagagcaggatgcccgaggcatggtggagttccaagagggtgtg gagctggtggacgtgcgtgtgcccctcttcatccggcctgaggatgacgatgagaagcag ctgctggtggaggccatcgatgtgcctgtgggcactgccactcttggccgccgcctggta aacatcaccatcatcaaggagcaagccagcggggtggtgtcctttgagcagcctgagtac ttggtcagccacggggagcaagtggcccgcattcctgttgtcaggcgcatcctggacaat ggcaaatcccaggtctcctaccgcactcaggacaacacagcccagggcaatcgggactat gtcccaatggagggtgagctgctgttccaccctggggagacctggaaggagttacaggtg aagctcctggagctgcaggaagtagattccctcctgcgaggacgccaaattcgccgcttc catgtccaactcagcaaccccaagttcggagcccgcctgggccagccccagtcggccaca gtcatcattggagagccagatgaactggaccggaaccttgtcagtcaggccctttcatca ctgccaccccctcgtggtgacctggacgctccacagaaccccaatgccaaagctgctggt tcccggaaaatccatttcaattggcttccccctcctggcaagccaacagggtacagggtg aagtactggatccagggtgactccgagtctgaagcccacctgctagacagtaaggtgccc tcggtggaactcaccaacctgtacccttactgtgactacgagatgaaggtgtgtgcctat ggagcacagggcgaggggccctacagctccctggtctcctgccgcacccaccaggaagta cccagcgagccagggcgtctggccttcaatgtggtctcttccacggtgacccagctgagc tgggcggagcctgctgagaccaatggcgagatcacagcgtacgaggtctgctatggcctg gtcaacgaggacaaccgacccattggacccatgaagaaggtgctggtggacaaccccaag aaccgaatgttgctcattgagaaccttcgagaatcccagccataccgctacacagtgaag gcgcgcaacggggcaggctgggggcctgaacgggaggccatcatcaacctagccacccag cctaagcggcccatgtccatccccatcatcccagacatccccattgtggatgcccagggc ggggaagactacgaaagcttcctcatgtacagtgatgacgtcctgcgctccccggctggc agccagaggcccagcgtctctgatgacactggcggtggctggaagttcgagcccctgctg ggggaggagctggacctgcgaagcatcacgtggctgctgcccccggagctcatcccgcgc ctgtcggtcagcagcgggcgctcctccgacgacagcggcacggggggcgcggccagggag ggaggcggccgggcccgcgcagcgacgccccggcctcccggagagcacttggtgaatggc cggatggactttgccttcccgggcagtgccaactccctgcacaggatgactgcggccaat gtggcttatgggacccacctgagcccacacctgccccacccaatgctgagcacatcctcc accctcacacgtgactaccactctctgacccgcacagaacactcacactctgccactctg cccagagaccgctctaccctcacctccctctcctcccagggcctccctcccatttgggaa gacgggaggagcaggcttccgctgtcctgggccctggggtcctggagtcgagctcagatg aaggggctccccaactccaggggctcccgagacactataatcctggctgggcagccagca tcaccatcctggggtccagatttccatatggctgtgggcgtacctgacacacctacccgg ctggtgttctctgccctggggcccacatctctgaaagtgagctggcaggagccacagagc gagcgtgtgctgctggggtacagcgtggagtaccagctgctgaatgggggcgagctgtat cgactcaacatccccaaccctgaccaaacttcggtggtggtggaagacctcctgcccaac cactcctatgtgttccgagtgcgggctcagagccaggagggctggggccgagagcgtgag ggtgtcattaccattgaatcacaggtgcacccgcagagcccactctgccccctgccaggc tctgccttcacgctgagcacccccagtgcccccggcccactggtattcacggccctcagc cctgactcactgcagctgagctgggagagaccacgcagacccaatggagatatcctcggt tacctggtgacctgcgagatggcccaaggaggaggaccagccaccacattccgggtggat ggagacaacctagagagccgactgacagtacctggcctcagtgagaatgtgccctacaag ttcaaagtacaggccaggaccactgagggcttcggaccagagcgggagggcgtcattacc attgagtcccaggatggaggccccttcccgcagctgggcagccactcagggctcttccag cacccactacagggcgagttcagcagcatcaccaccacccacaccagcaccactgagccc ttccttgtggatggattgaccctggggtcccaacacctggaggcaagtggctccctcacc cggcatgtgacccaggaatttgtgagccggaccctgactaccagtggaaccctcagcacc caggtgtcggaccaacaattcttccaaccctga

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