KEGG   Castor canadensis (American beaver): 109696190
Entry
109696190         CDS       T04791                                 
Symbol
Ddb2
Name
(RefSeq) DNA damage-binding protein 2 isoform X1
  KO
K10140  DNA damage-binding protein 2
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan03420  Nucleotide excision repair
ccan04115  p53 signaling pathway
ccan04120  Ubiquitin mediated proteolysis
ccan05161  Hepatitis B
ccan05169  Epstein-Barr virus infection
ccan05200  Pathways in cancer
ccan05202  Transcriptional misregulation in cancer
ccan05210  Colorectal cancer
ccan05212  Pancreatic cancer
ccan05213  Endometrial cancer
ccan05214  Glioma
ccan05216  Thyroid cancer
ccan05217  Basal cell carcinoma
ccan05218  Melanoma
ccan05220  Chronic myeloid leukemia
ccan05222  Small cell lung cancer
ccan05223  Non-small cell lung cancer
ccan05224  Breast cancer
ccan05225  Hepatocellular carcinoma
ccan05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    109696190 (Ddb2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    109696190 (Ddb2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    109696190 (Ddb2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109696190 (Ddb2)
   05202 Transcriptional misregulation in cancer
    109696190 (Ddb2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109696190 (Ddb2)
   05212 Pancreatic cancer
    109696190 (Ddb2)
   05225 Hepatocellular carcinoma
    109696190 (Ddb2)
   05226 Gastric cancer
    109696190 (Ddb2)
   05214 Glioma
    109696190 (Ddb2)
   05216 Thyroid cancer
    109696190 (Ddb2)
   05220 Chronic myeloid leukemia
    109696190 (Ddb2)
   05217 Basal cell carcinoma
    109696190 (Ddb2)
   05218 Melanoma
    109696190 (Ddb2)
   05213 Endometrial cancer
    109696190 (Ddb2)
   05224 Breast cancer
    109696190 (Ddb2)
   05222 Small cell lung cancer
    109696190 (Ddb2)
   05223 Non-small cell lung cancer
    109696190 (Ddb2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    109696190 (Ddb2)
   05169 Epstein-Barr virus infection
    109696190 (Ddb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:ccan04121]
    109696190 (Ddb2)
   03400 DNA repair and recombination proteins [BR:ccan03400]
    109696190 (Ddb2)
Ubiquitin system [BR:ccan04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     109696190 (Ddb2)
DNA repair and recombination proteins [BR:ccan03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      109696190 (Ddb2)
SSDB
Motif
Pfam: WD40_CDC20-Fz WD40 WD40_WDHD1_1st WD40_Prp19 Beta-prop_EML_2 Beta-prop_RIG_2nd Beta-prop_WDR75_1st WDR55 Beta-prop_IFT140_1st Beta-prop_WDR90_POC16_2nd Beta-prop_WDR19_1st Beta-prop_TEP1_2nd Beta-prop_EIPR1 EIF3I WD40_RFWD3 Beta-prop_TEP1_C Beta-prop_CAF1B_HIR1 Beta-prop_HPS5 NBCH_WD40 WD40_MABP1-WDR62_2nd Beta-prop_Vps41 Beta-prop_NWD2_C Beta-prop_WDR35_TULP_N
Other DBs
NCBI-GeneID: 109696190
NCBI-ProteinID: XP_020034722
UniProt: A0A8B7VSW5
LinkDB
Position
Unknown
AA seq 431 aa
MASKKRPETQKSPEVVRLRSRRSRSPRELEPQAKRLRVKSSGSSRRGDSGCLWAGLASLQ
VPPPCSSIIRDLYRHKLGEAAWPSLQQGLQQSFLHSLASYQIFQKAAPFDRRATSLAWHP
THPSTLAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNLLNTNQFFASSMEGTT
RLQDFKGNTVRVFTSSNTCNVWFCSLDVSAKSRVVVTGDNVGHVILLNTDGKELWNLRMH
KKKVTHVALNPCCDWLLATASVDQTVKIWDLRQVRGKASFLFSLPHRHPVNAACFSPDGA
RLLTTDQKSEIRVYSASQWDCPLGLIPHPHRHFQHLTPIKAAWHPRHNLIVAGRYPDPSF
KSCAPYELRTIDVFDGNSGKMMCQLYDPESSGIISLNEFNPMGDTLASAMGYHILIWSQE
KAGPQKENERQ
NT seq 1296 nt   +upstreamnt  +downstreamnt
atggcttccaagaaacgcccagaaacccagaagtcccctgaggtcgtgcgcctcaggagc
aggaggagcagaagcccccgggagctggagcctcaggccaagaggctccgtgtgaagagc
tccggttctagtaggagaggtgactcaggctgcctttgggcagggctggctagcctgcaa
gtcccaccaccgtgcagcagcatcatcagggacctctaccggcataagttgggtgaagct
gcctggccttcactacagcagggtctccagcagtcctttttgcactctctggcttcttac
cagatattccaaaaagctgcgccctttgacaggagagctacatccttggcatggcacccg
actcaccccagcaccctggctgtgggttccaaaggaggagatatcatgctctggaacttt
ggcataaaggacaaacccaccttcattaaagggattggagctggagggagcatcactggg
ctgaaatttaatcttctcaataccaaccagttttttgcctcctcaatggagggaacaact
aggctgcaagactttaaaggcaacactgtccgagtttttaccagctcaaacacctgcaat
gtctggttttgcagcctggatgtgtctgccaaaagccgagtggtcgtcacaggagataat
gtggggcatgtaatcctgctgaacacagatggcaaggagctttggaatctcagaatgcat
aaaaagaaagtgactcatgtggctctgaacccctgctgtgattggttactggccacagcc
tctgtagatcaaacagtgaaaatctgggacctgcgccaggttagagggaaagccagcttc
ctcttctcgctgccacacaggcatcctgtcaacgcagcttgtttcagcccagatggagcc
cgcctcctaactactgaccagaagagtgagatccgggtttactctgcctcccagtgggac
tgcccccttggacttatcccccaccctcaccgtcacttccagcacctcacacctattaag
gcagcctggcatcctcggcacaacctcattgttgcaggccgttatccagatcctagtttc
aaaagttgtgccccctatgaactgaggacgattgatgtatttgatggaaactcagggaag
atgatgtgtcagctctatgacccagaatcttctggtatcatttcgctcaatgaattcaac
ccaatgggggacacactggcctctgccatgggttatcacattctcatttggagccaggag
aaagctgggccacagaaagaaaatgaaagacaatga

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