KEGG   Castor canadensis (American beaver): 109697389
Entry
109697389         CDS       T04791                                 
Symbol
Mapk11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan01522  Endocrine resistance
ccan04010  MAPK signaling pathway
ccan04015  Rap1 signaling pathway
ccan04068  FoxO signaling pathway
ccan04071  Sphingolipid signaling pathway
ccan04114  Oocyte meiosis
ccan04148  Efferocytosis
ccan04218  Cellular senescence
ccan04261  Adrenergic signaling in cardiomyocytes
ccan04370  VEGF signaling pathway
ccan04380  Osteoclast differentiation
ccan04550  Signaling pathways regulating pluripotency of stem cells
ccan04611  Platelet activation
ccan04613  Neutrophil extracellular trap formation
ccan04620  Toll-like receptor signaling pathway
ccan04621  NOD-like receptor signaling pathway
ccan04622  RIG-I-like receptor signaling pathway
ccan04625  C-type lectin receptor signaling pathway
ccan04657  IL-17 signaling pathway
ccan04658  Th1 and Th2 cell differentiation
ccan04659  Th17 cell differentiation
ccan04660  T cell receptor signaling pathway
ccan04664  Fc epsilon RI signaling pathway
ccan04668  TNF signaling pathway
ccan04670  Leukocyte transendothelial migration
ccan04714  Thermogenesis
ccan04722  Neurotrophin signaling pathway
ccan04723  Retrograde endocannabinoid signaling
ccan04728  Dopaminergic synapse
ccan04750  Inflammatory mediator regulation of TRP channels
ccan04912  GnRH signaling pathway
ccan04914  Progesterone-mediated oocyte maturation
ccan04917  Prolactin signaling pathway
ccan04926  Relaxin signaling pathway
ccan04932  Non-alcoholic fatty liver disease
ccan04933  AGE-RAGE signaling pathway in diabetic complications
ccan04935  Growth hormone synthesis, secretion and action
ccan04936  Alcoholic liver disease
ccan05014  Amyotrophic lateral sclerosis
ccan05020  Prion disease
ccan05022  Pathways of neurodegeneration - multiple diseases
ccan05132  Salmonella infection
ccan05133  Pertussis
ccan05135  Yersinia infection
ccan05140  Leishmaniasis
ccan05142  Chagas disease
ccan05145  Toxoplasmosis
ccan05152  Tuberculosis
ccan05161  Hepatitis B
ccan05163  Human cytomegalovirus infection
ccan05167  Kaposi sarcoma-associated herpesvirus infection
ccan05169  Epstein-Barr virus infection
ccan05170  Human immunodeficiency virus 1 infection
ccan05171  Coronavirus disease - COVID-19
ccan05205  Proteoglycans in cancer
ccan05208  Chemical carcinogenesis - reactive oxygen species
ccan05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ccan05415  Diabetic cardiomyopathy
ccan05417  Lipid and atherosclerosis
ccan05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109697389 (Mapk11)
   04015 Rap1 signaling pathway
    109697389 (Mapk11)
   04370 VEGF signaling pathway
    109697389 (Mapk11)
   04668 TNF signaling pathway
    109697389 (Mapk11)
   04068 FoxO signaling pathway
    109697389 (Mapk11)
   04071 Sphingolipid signaling pathway
    109697389 (Mapk11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    109697389 (Mapk11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    109697389 (Mapk11)
   04218 Cellular senescence
    109697389 (Mapk11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    109697389 (Mapk11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    109697389 (Mapk11)
   04613 Neutrophil extracellular trap formation
    109697389 (Mapk11)
   04620 Toll-like receptor signaling pathway
    109697389 (Mapk11)
   04621 NOD-like receptor signaling pathway
    109697389 (Mapk11)
   04622 RIG-I-like receptor signaling pathway
    109697389 (Mapk11)
   04625 C-type lectin receptor signaling pathway
    109697389 (Mapk11)
   04660 T cell receptor signaling pathway
    109697389 (Mapk11)
   04658 Th1 and Th2 cell differentiation
    109697389 (Mapk11)
   04659 Th17 cell differentiation
    109697389 (Mapk11)
   04657 IL-17 signaling pathway
    109697389 (Mapk11)
   04664 Fc epsilon RI signaling pathway
    109697389 (Mapk11)
   04670 Leukocyte transendothelial migration
    109697389 (Mapk11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    109697389 (Mapk11)
   04914 Progesterone-mediated oocyte maturation
    109697389 (Mapk11)
   04917 Prolactin signaling pathway
    109697389 (Mapk11)
   04926 Relaxin signaling pathway
    109697389 (Mapk11)
   04935 Growth hormone synthesis, secretion and action
    109697389 (Mapk11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    109697389 (Mapk11)
  09156 Nervous system
   04728 Dopaminergic synapse
    109697389 (Mapk11)
   04723 Retrograde endocannabinoid signaling
    109697389 (Mapk11)
   04722 Neurotrophin signaling pathway
    109697389 (Mapk11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    109697389 (Mapk11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    109697389 (Mapk11)
  09159 Environmental adaptation
   04714 Thermogenesis
    109697389 (Mapk11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    109697389 (Mapk11)
   05208 Chemical carcinogenesis - reactive oxygen species
    109697389 (Mapk11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109697389 (Mapk11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    109697389 (Mapk11)
   05161 Hepatitis B
    109697389 (Mapk11)
   05171 Coronavirus disease - COVID-19
    109697389 (Mapk11)
   05163 Human cytomegalovirus infection
    109697389 (Mapk11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109697389 (Mapk11)
   05169 Epstein-Barr virus infection
    109697389 (Mapk11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109697389 (Mapk11)
   05135 Yersinia infection
    109697389 (Mapk11)
   05133 Pertussis
    109697389 (Mapk11)
   05152 Tuberculosis
    109697389 (Mapk11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    109697389 (Mapk11)
   05140 Leishmaniasis
    109697389 (Mapk11)
   05142 Chagas disease
    109697389 (Mapk11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    109697389 (Mapk11)
   05020 Prion disease
    109697389 (Mapk11)
   05022 Pathways of neurodegeneration - multiple diseases
    109697389 (Mapk11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109697389 (Mapk11)
   05418 Fluid shear stress and atherosclerosis
    109697389 (Mapk11)
   05415 Diabetic cardiomyopathy
    109697389 (Mapk11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109697389 (Mapk11)
   04932 Non-alcoholic fatty liver disease
    109697389 (Mapk11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    109697389 (Mapk11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    109697389 (Mapk11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccan01001]
    109697389 (Mapk11)
Enzymes [BR:ccan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     109697389 (Mapk11)
Protein kinases [BR:ccan01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   109697389 (Mapk11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975 Kinase-like
Other DBs
NCBI-GeneID: 109697389
NCBI-ProteinID: XP_020036555
UniProt: A0A8C0ZPL4
LinkDB
Position
Unknown
AA seq 364 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDTQLRQKVAVKKLSRPFQ
SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYSQAVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFHEANPLAVDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPEAEPYDDSVEAKERTVEEWKELTYQEVLSFKPPELLQPPGTC
EIEQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcgggcccgcgcgccggcttctaccggcaggagctgaataagaccgtgtgggaggtg
ccgcagcggctgcagggcctgcgcccggtgggctccggcgcctacggctcagtctgctcg
gcctacgacacacagctccgccagaaggtggcagtgaagaagctgtcccgcccctttcag
tcactgatccatgcgcgaagaacgtaccgtgagctgcggctgctcaaacatctgaagcac
gagaacgtcattggtcttctggacgtcttcacgcctgctacgtccattgaggacttcagc
gaagtgtacctggtgaccactttgatgggtgccgacttgaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgttcagttcctcgtttaccagctgctgcgcgggctgaagtac
atccattcggcggggatcatccaccgggacttgaagcccagcaacgtggcggtgaatgag
gactgcgagctcaggattctggactttgggcttgcgcgtcaggctgacgaggagatgaca
ggatacgtggccacacgctggtaccgggcgcctgagatcatgctcaattggatgcactac
agtcaagcagtggacatctggtctgtgggctgcatcatggctgagctgctccagggaaag
gccctcttccctggaaatgactacattgaccagctgaaacgcatcatggaggtggtgggc
acacccagccctgaggttctggcaaagatatcctcggagcatgcccggacatacatccag
tccctgccccccatgccccagaaggacctcagcagcatcttccatgaagccaaccccctg
gctgtagacctccttggaaggatgctggtgctggacagtgaccagagggtcagcgcagct
gaggccctggctcatgcatacttcagccagtaccacgacccggatgatgagccagaggct
gagccctatgacgacagtgttgaggccaaggagcgcacagtggaggagtggaaggagctc
acttaccaggaagtcctcagcttcaagcctccagagctgctgcagccacctggcacctgt
gagattgagcagtga

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