| Entry |
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| Symbol |
Abcc1
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| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
ccan Castor canadensis (American beaver)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:ccan00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
109697739 (Abcc1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
109697739 (Abcc1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
109697739 (Abcc1)
04981 Folate transport and metabolism
109697739 (Abcc1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
109697739 (Abcc1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
109697739 (Abcc1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:ccan02000]
109697739 (Abcc1)
Enzymes [BR:ccan01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
109697739 (Abcc1)
Transporters [BR:ccan02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
109697739 (Abcc1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1569 aa
MAPTPSGAHPGPKPSPRIQKEAGMDVGRPLSEPSGAGQEPFYISTSVSTAVKWGTDWNVT
WYTSNPDFTKCFQNTVLVWVPCLYLWACFPFYFLYLSRHDRGYIQMTHLNKTKTALGFLL
WVVCWADLFYSFWERSWGVLLAPVLLVSPTLLGITMLLATLLIQLERRKGVQSSGIMLTF
WLVALLCALAILRSRIMTALKEDTQVDLFRDVTFYVYLSLVLIQLVLSCFSDRSPLFSET
ISDSNPCPESGASFLSRITFWWITGLMIRGYRQPLEASDLWSLNKEDTSEQVVPVLVKNW
KKECAKSRKQPVRVVYSAKEPAKPREGSKVDVNEEAEALIVKAPQKERAPSLFKVLYKTF
GPYFLVSFFFKALHDLMMFAGPEILKLLINFVNDTQAPDWQGYFYTALLFISACLQTLVL
HQYFHICFVSGMRVKTAVIGAVYRKALVITSSARKSSTVGEIVNLMSVDAQRFMDLATYI
NMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPFNAVMAMKTKTYQVAHMKSKDNR
IKLMNEILNGIKVLKLYAWELAFKDKVMAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVA
LSTFAVYVTVDKNNVLDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRVFLS
HEELEPDSIERRPMKDGGGTNSITVKNATFTWSRGEPPTLTGITFSIPDGALVAVVGQVG
CGKSSLLSALLAEMDKVEGQVALKGSVAYVPQQAWIQNDSLRENILFGRPLQERYYKAVM
EACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDIYLFDDPLSAVDAH
VGKHIFENVIGPKGMLQNKTRLLVTHGISYLPQVDVIVVMSGGKISEMGSYQELLARDGA
FAEFLRTYASTEQDQTLEEEGLTGLSGPGKEAKPMENGVLVTDTSGKHLQRQLSSASSYS
GDTSRHHASSAELHKAGAKEETWKLMEADKAQTGQVQLSVYWDYMKAIGLFISFLSIFLF
LCNHVSALASNYWLSLWTDDPIVNGTQEHTKVRLSVYGALGISQGVAVFGYSMAVSVGGI
LASRRLHLDLLHSVLRSPVSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVL
GACVIILLATPVAAAIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYSHFSETLLGV
SVIRAFEDQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLEYVGNCIVLFAALFAVISR
HSLSAGLVGLSVSYSLQITAYLNWLVRMSSEMETNIVAVERLKEYSEIEKEAPWQIQETA
PPSNWPQVGRVEFRDYGLRYREDLDLVLKHISITIDGGEKVGIVGRTGAGKSSLTLGLFR
INESAEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTA
LELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDL
ETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYMRVIVLDKGEIRECGPPSDLLQQRGIFY
SMAKDAGLV |
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| NT seq |
4710 nt +upstreamnt +downstreamnt
atggctccgaccccttctggtgcccaccctgggccaaagccaagtccaaggatccagaag
gaagctggcatggacgtgggtaggcccctgagtgagccttctggtgcaggccaggagcca
ttttacatcagcacctcagtttccacagctgttaaatggggaacggactggaatgtcacg
tggtacaccagcaaccccgacttcaccaagtgctttcagaacaccgtcctcgtgtgggtg
ccctgtttgtacctctgggcctgtttccccttctacttcctctatctctcccgacacgac
cggggctatattcagatgacacacctcaacaaaaccaaaactgccttggggttccttctg
tgggtcgtctgctgggcagatctcttctactctttctgggaaagaagttggggtgtgttg
ctggccccggtgttgctggtcagcccaaccctcttgggcatcaccatgctgctcgctacc
cttttaattcagctcgagcgaaggaagggagtccagtcctcagggatcatgctcactttc
tggcttgtagccctactgtgtgccctggccatcttgagatccagaatcatgactgcctta
aaagaggacactcaagtggacctgttccgcgatgtcactttctacgtgtacctttccctt
gtgctcattcagctcgtgctgtcctgcttctcagaccgatcgcccctgttctccgaaacc
atcagtgactccaatccttgcccggagtccggtgcctcattcctttccaggatcaccttc
tggtggatcacagggttgatgatccggggctaccgccagcccctggaggccagtgacctc
tggtcgctgaacaaggaggacacttcagaacaagtggtgccggtgttggtgaagaactgg
aagaaggagtgtgccaagtctcggaagcagcctgtgagggtcgtgtactctgccaaggag
cctgccaagcccagagagggttccaaggtggatgtgaacgaggaggcggaggccctgatt
gtcaaggccccgcagaaggagcgtgccccctccttgttcaaggtgttgtacaagaccttc
gggccctacttcctcgtgagcttcttcttcaaggctctgcatgacctcatgatgttcgct
ggccccgagatcttgaagttgctcatcaactttgtgaacgacacacaggcgcctgactgg
cagggctatttctacacagcgctgctgttcatcagtgcctgcctgcagacgctggtgctg
caccagtacttccatatctgcttcgtcagcggcatgcgtgtcaagaccgctgtgattggg
gctgtgtaccggaaggccctggtgatcaccagctcagcgagaaagtcatccacggttgga
gagattgtcaacctcatgtctgtggacgcccagaggttcatggacttggccacgtacatt
aacatgatctggtcagcccctctgcaagtcatccttgctctctacctcctgtggctgaac
ctgggtccctctgtcctggctggtgtggctgtgatgatccttatggtgcctttcaatgct
gtgatggccatgaagaccaaaacctaccaggtggcccacatgaagagcaaggacaatcgg
attaaactgatgaacgaaattctcaacgggatcaaggtactcaagctgtacgcctgggag
ctggcattcaaggacaaggtgatggccatcaggcaggaggagctgaaggtgctcaagaag
tctgcctacctggctgccgtggggaccttcacctgggtgtgcacaccgttcctggtggcc
ctgtctacttttgccgtctatgtgaccgtggacaagaacaacgtcctggatgcacagaag
gccttcgtgtccttggccttgttcaacatccttcgtttccccctcaacatcctccccatg
gtcatcagcagcatcgtgcaggccagtgtgtccctcaagcgcctgagggtcttcctgtcc
cacgaggagctggagccagacagcattgagcggaggcccatgaaggatggcgggggaaca
aacagcattactgtgaagaatgccacattcacgtggtccaggggagaacctcccacgctc
actggcatcaccttctccatcccggacggcgccctggtggccgtggtgggccaggtgggc
tgtgggaagtcctctctgctctcagccctcttggctgagatggacaaggtggagggacaa
gtggctctcaagggctcggtggcctacgtcccccagcaggcctggattcagaatgactct
ctgagagaaaacatcctttttgggcgcccgctgcaggagcggtattacaaggccgtgatg
gaggcctgtgccctcctcccggacctggaaatcctgcccagcggggaccggaccgagatc
ggcgagaagggtgtgaacctgtcggggggccagaagcagcgcgtgagcctggcccgggct
gtgtactgcgactcggacatctacctcttcgatgacccgctctcggccgtggacgcccac
gtggggaagcacatctttgaaaacgtgattggtcctaaggggatgctgcagaacaagaca
cggctcctggttacacatggcatcagctacctgccacaggtggacgtcatcgtggtcatg
agtggcgggaagatctcagagatgggctcctaccaggagctgctggcccgggacggggcc
tttgctgagttcctgcgcacatacgccagcactgagcaggaccagaccttggaggaggag
gggttaacaggcctcagtggtccagggaaggaggcaaagccgatggagaatggcgtgcta
gtgacggacacctcagggaagcacctgcagaggcagctgagcagcgcctcctcctacagt
ggggacaccagcaggcaccacgccagcagtgccgagctgcacaaggctggggccaaggag
gagacctggaagctgatggaggcggacaaggcgcagacaggccaggtgcagctgtccgtg
tactgggactacatgaaagctattgggcttttcatatccttcctgagcatcttcctcttc
ctgtgcaaccacgtctctgccctggcctccaactactggctcagcctctggacagacgac
cccattgtcaatgggacccaggagcacacaaaggtccggctgagcgtctatggagccctg
ggcatctcacaaggcgtcgccgtgttcggctactccatggccgtgtccgtgggcggcatc
ctggcctcccgtcgcctgcacctggacctgctgcacagtgtgctgcgctcgcccgtcagc
ttcttcgagcgcacgcccagcgggaacctggtgaaccgcttctccaaggagctggacacg
gtggactccatgatcccgcaggtcattaagatgtttatgggctccctgttcaacgtcctg
ggcgcctgcgtcatcatcctgctggccacgcctgtcgctgcggccatcatcccgcccctc
ggccttgtctacttcttcgtgcagcggttctatgtggcctccagccggcagctgaagcgc
ctcgagtcggtcagtcgctccccggtctattcacacttcagcgagaccttgctgggggtc
agcgtcatccgtgcctttgaggaccaggagcgcttcatccgccagagcgacctcaaggtg
gatgagaaccagaaggcttattaccccagcatcgtggccaacaggtggctggccgtgcgg
ctggagtatgtcggcaactgcattgttctgtttgctgccctgtttgcagtcatctccagg
cacagcctcagcgctggcttggtgggcctctccgtgtcttactccttgcagatcacggca
tacttgaactggctagttcggatgtcgtctgagatggagaccaacattgtggccgtagag
agactcaaggaatattcagaaatcgagaaagaggctccctggcagatccaggagactgcg
ccacccagcaactggccacaggtgggccgagtggagttccgggactatggcctgcgctac
cgagaggacctggacttggttctcaaacacatcagcatcaccattgatgggggagaaaag
gttggcatcgtgggtcggacaggagctgggaagtcatctctgaccttgggcttgtttcgg
atcaatgaatctgcagaaggagaaatcatcattgatggcgtcaacattgccaagattggc
ctgcacaacctgcgcttcaagatcactatcatcccccaggaccctgttttgttctcgggt
tccctccgcatgaacctggacccattcagccagtactcggatgaagaggtctggacggcc
ctggagctggcgcacctgaagggcttcgtgtcagcccttcctgacaagctgaaccacgag
tgcgcagaaggtggcgagaacctgagtgttgggcagcgccagcttgtgtgtctggcccgg
gctctgctgaggaagacgaagattcttgtgttggatgaggccacagcagccgtggacctg
gaaacggacaacctcattcagtccaccatcagaacacagtttgaggactgcaccgtgctc
accattgcccaccgactcaacaccatcatggactacatgagggtgatcgtcctggacaaa
ggagaaatccgggagtgcggccccccctccgacctcctgcagcagaggggtatcttctac
agcatggccaaagatgctggcttggtgtga |
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