KEGG   Castor canadensis (American beaver): 109697782
Entry
109697782         CDS       T04791                                 
Symbol
Mgst1
Name
(RefSeq) microsomal glutathione S-transferase 1 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan00480  Glutathione metabolism
ccan00980  Metabolism of xenobiotics by cytochrome P450
ccan00982  Drug metabolism - cytochrome P450
ccan00983  Drug metabolism - other enzymes
ccan01100  Metabolic pathways
ccan01524  Platinum drug resistance
ccan05200  Pathways in cancer
ccan05204  Chemical carcinogenesis - DNA adducts
ccan05207  Chemical carcinogenesis - receptor activation
ccan05208  Chemical carcinogenesis - reactive oxygen species
ccan05225  Hepatocellular carcinoma
ccan05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    109697782 (Mgst1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    109697782 (Mgst1)
   00982 Drug metabolism - cytochrome P450
    109697782 (Mgst1)
   00983 Drug metabolism - other enzymes
    109697782 (Mgst1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109697782 (Mgst1)
   05204 Chemical carcinogenesis - DNA adducts
    109697782 (Mgst1)
   05207 Chemical carcinogenesis - receptor activation
    109697782 (Mgst1)
   05208 Chemical carcinogenesis - reactive oxygen species
    109697782 (Mgst1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    109697782 (Mgst1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    109697782 (Mgst1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    109697782 (Mgst1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ccan02000]
    109697782 (Mgst1)
Enzymes [BR:ccan01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     109697782 (Mgst1)
Transporters [BR:ccan02000]
 Other transporters
  Pores ion channels [TC:1]
   109697782 (Mgst1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 109697782
NCBI-ProteinID: XP_020037218
UniProt: A0A8B7W010
LinkDB
Position
Unknown
AA seq 191 aa
MCLMLQYKLIKRQWYLCLFFPFLSKIFLRFQIKIEKMAHLNQLLENEVFMAFTSYATIIL
TKMMFMSTATAFYRLKRKVFANPEDYAAFGKEENAKKYLQTDDRVERVRRAHLNDLENIV
PFLGIGLLYSLSGPDLSTALLHFRLFVGARIYHTIAYLTPFPQPNRGLAFFVGFGVTFSM
AYRLLKSRLYL
NT seq 576 nt   +upstreamnt  +downstreamnt
atgtgtttaatgctgcaatataaactcattaagagacaatggtatttgtgcttgtttttc
ccctttttgtccaaaatctttttaagattccagatcaaaattgaaaaaatggctcatctc
aaccagctgttggaaaatgaagtcttcatggcctttacctcttacgcaacaattattctt
acaaaaatgatgtttatgagcactgcaactgcattctacagactaaaaaggaaggttttt
gccaacccagaagactatgcagcctttggcaaggaagagaatgccaagaaatatcttcaa
acagatgacagggtggaacgcgtacgaagagcccacctgaatgaccttgaaaacattgtt
ccatttcttgggatcggcctgttgtattccttgagtggtccagatctctctacagccctc
ctgcacttcagactctttgttggagcacggatctaccacacaattgcctatctgacaccc
tttccacagccaaatagagggttggctttttttgttggatttggagttaccttttcaatg
gcctacagattactgaagagtagattgtacctgtga

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