KEGG   Castor canadensis (American beaver): 109698434
Entry
109698434         CDS       T04791                                 
Symbol
Map2k7
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 7 isoform X1
  KO
K04431  mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan04010  MAPK signaling pathway
ccan04012  ErbB signaling pathway
ccan04141  Protein processing in endoplasmic reticulum
ccan04380  Osteoclast differentiation
ccan04530  Tight junction
ccan04620  Toll-like receptor signaling pathway
ccan04660  T cell receptor signaling pathway
ccan04664  Fc epsilon RI signaling pathway
ccan04668  TNF signaling pathway
ccan04722  Neurotrophin signaling pathway
ccan04912  GnRH signaling pathway
ccan04926  Relaxin signaling pathway
ccan04936  Alcoholic liver disease
ccan05010  Alzheimer disease
ccan05016  Huntington disease
ccan05022  Pathways of neurodegeneration - multiple diseases
ccan05132  Salmonella infection
ccan05135  Yersinia infection
ccan05161  Hepatitis B
ccan05167  Kaposi sarcoma-associated herpesvirus infection
ccan05169  Epstein-Barr virus infection
ccan05170  Human immunodeficiency virus 1 infection
ccan05208  Chemical carcinogenesis - reactive oxygen species
ccan05417  Lipid and atherosclerosis
ccan05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    109698434 (Map2k7)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109698434 (Map2k7)
   04012 ErbB signaling pathway
    109698434 (Map2k7)
   04668 TNF signaling pathway
    109698434 (Map2k7)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    109698434 (Map2k7)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    109698434 (Map2k7)
   04660 T cell receptor signaling pathway
    109698434 (Map2k7)
   04664 Fc epsilon RI signaling pathway
    109698434 (Map2k7)
  09152 Endocrine system
   04912 GnRH signaling pathway
    109698434 (Map2k7)
   04926 Relaxin signaling pathway
    109698434 (Map2k7)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    109698434 (Map2k7)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    109698434 (Map2k7)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    109698434 (Map2k7)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    109698434 (Map2k7)
   05161 Hepatitis B
    109698434 (Map2k7)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109698434 (Map2k7)
   05169 Epstein-Barr virus infection
    109698434 (Map2k7)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109698434 (Map2k7)
   05135 Yersinia infection
    109698434 (Map2k7)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    109698434 (Map2k7)
   05016 Huntington disease
    109698434 (Map2k7)
   05022 Pathways of neurodegeneration - multiple diseases
    109698434 (Map2k7)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109698434 (Map2k7)
   05418 Fluid shear stress and atherosclerosis
    109698434 (Map2k7)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109698434 (Map2k7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccan01001]
    109698434 (Map2k7)
Enzymes [BR:ccan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     109698434 (Map2k7)
Protein kinases [BR:ccan01001]
 Serine/threonine kinases: STE group
  STE7 family
   109698434 (Map2k7)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase APH
Other DBs
NCBI-GeneID: 109698434
NCBI-ProteinID: XP_020038237
UniProt: A0A250YI75
LinkDB
Position
Unknown
AA seq 435 aa
MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPIIVITLSPAPAPSQRAALQ
LPLANDGGSRSPSSESSPQHPTPPARPRHMLGLPPTLFTPRSMESIEIDQKLQEIMKQTG
YLTIGGQRYQAEINDLENLGEMGSGTCGQVWKMRFRKTGHIIAVKQMRRSGNKEENKRIL
MDLDVVLKSHDCPYIVQCFGTFITNTDVFIAMELMGTCAEKLKKRMQGPIPERILGKMTV
AIVKALYYLKEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYM
APERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLP
SHMGFSGDFQSFVKDCLTKDHRKRPKYNKLLEHSFIKRYEMLEVDVASWFKDVMAKTESP
RTSGALSQHHLPLFR
NT seq 1308 nt   +upstreamnt  +downstreamnt
atggcggcgtcctccctggagcaaaagctgtcccgactagaagcaaagctgaagcaggag
aaccgcgaggcccggaggaggatcgacctcaacctggatatcagcccccagcggcccagg
cccattattgtgatcactctaagccctgctcctgccccgtcccagcgagcagccctgcag
ctcccgctggccaatgatgggggcagccgttcgccgtcctcagagagctctccacagcac
cccacaccccccgcccggccccgccacatgctggggctcccgccgaccttgttcacaccc
cgcagcatggagagcatcgagatcgatcagaagttgcaggagatcatgaaacagacaggc
tacctaaccatcgggggccagcgctatcaggcagaaatcaatgacctcgagaatctgggt
gagatgggcagtggtacctgtggccaggtatggaagatgcgcttccggaagacaggccac
atcattgccgtcaagcaaatgaggcgctcggggaacaaggaggagaacaaacgcatcctc
atggacctcgatgtggtgctcaagagccacgactgcccctacattgttcagtgcttcggc
accttcatcaccaacactgacgtcttcattgccatggagctcatgggcacctgtgcagag
aagcttaagaagcggatgcagggccctatccctgagcggatcctgggcaagatgactgtg
gcgattgtgaaggcgctgtactacctgaaggagaaacacggcgtcatccaccgagacgtc
aagccctccaacatcctgctggatgagcggggccagatcaagctctgtgactttggcatc
agtggccgcctcgtcgactccaaggccaaaacacggagcgctggctgtgccgcctacatg
gcacctgagcgcatagatcccccggatcccaccaagcctgactatgacatccgggctgat
gtgtggagcctgggtatctccttggtggagctggcaacaggacagtttccctacaagaat
tgcaagacggactttgaggtcctcaccaaagtcctacaggaagaacccccgctcctgccc
agtcacatgggcttctcgggggacttccagtcgttcgtcaaagactgccttactaaagat
cacaggaagagaccaaagtataataagctacttgaacatagcttcatcaagcgctatgag
atgctcgaggtggatgtggcatcctggttcaaggatgtcatggcaaagaccgagtcaccg
cggactagtggagccctgagccaacatcatctgcccttattcaggtag

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