| Entry |
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| Symbol |
Abcc4
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| Name |
(RefSeq) multidrug resistance-associated protein 4 isoform X1
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| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
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| Organism |
ccan Castor canadensis (American beaver)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:ccan00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
109698762 (Abcc4)
09132 Signal transduction
04024 cAMP signaling pathway
109698762 (Abcc4)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
109698762 (Abcc4)
04981 Folate transport and metabolism
109698762 (Abcc4)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
109698762 (Abcc4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:ccan02000]
109698762 (Abcc4)
Transporters [BR:ccan02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
109698762 (Abcc4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1216 aa
MLPVHTEVKPNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYSVLPQDRSKHLGEEL
QGYWDKEVFRAKKDARKPSLTKAIIKCYWKSYVILGIFTLIEEGTKVIQPIFLGKVINYF
ESYDPSDSVALHTAYGYATVLTVCTLFLAILHHLYFYHVQCAGMRLRVAMCHMIYKKALR
LSNMAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAVAVTVLLWMEIGISCLAG
MAVLIILLPLQSCIGKLFSSLRSKTAAFTDARIRTMNEVITGIRIIKMYAWEKSFADLIA
SLRRKEISKVLKSSYLRGMNLASFFVANKIILFVTFTTYVLLGNVITASRVFVAMTLYGA
VRLTVTLFFPAAIERVSEAIVSIRRIQNFLVLDEVSRRTPQPPSDGKALVHVQDFTAFWD
KALETPTLQGLSFTVRPGELLAVVGPVGAGKSSLLSAVLGELPPSQGLVSVHGRIAYVSQ
QPWVFSGTVRSNILFGKKYEKERYEKVIKACALKKDLQLLEDGDLTVIGDRGATLSGGQK
ARVNLARAVYQDADIYLLDDPLSAVDAEVGKHLFQLCICQTLHEKITILVTHQLQYLKAA
SQILILKDGKMVQKGTYTEFLKSGVDFGSLLKKENEEAEQSPAPGTPTLRNRTFSESSVW
SQQSSRLSLKDGAQEGQDTEDTPVVQSEASRSEGKVGFKAYKNYFTAGASWFVIIFLILL
NIAAQVAYVLQDWWLSYWANEQSRLNTTVNGEGNTTEKLDLTWYLGIYGGLTGATVLFGI
ARSLLVFHVLVNSSQTLHNKMFESILRAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLTF
LDFIQTLLLVISVVAIAAAVIPWIAIPLVPLAIIFLVLRRYFLETSRDVKRLESTTRSPV
FSHLSSSLQGLWTIRAYRAEDRCQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIFV
IVVAFGSLILAKTLDGGQVGLALSYALTLMGMFQWSVRQSAEVENMMISVERVIEYTDLE
KEAPWEYQKRPPPAWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSREKVGIVGRTGAG
KSSLISALFRLSEPEGKIWIDKILTSEIGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFNE
HTDEELWNALKEVQLKEAIEDLPGKMDTELAESGSNFSVGQRQLVCLARAILKKNRILII
DEATANVDPRFWIQED |
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| NT seq |
3651 nt +upstreamnt +downstreamnt
atgctcccggtccataccgaggtgaagcccaacccgctgcaggacgccaacctctgctcg
cgcgtgttcttctggtggttaaaccccttgtttaaaattggtcataaaaggagattagaa
gaagatgatatgtattcagtgcttccgcaagatcgctcaaaacaccttggagaagagcta
caagggtactgggataaagaagtcttcagagccaagaaggatgcacggaagccttcgtta
acaaaagcaatcataaagtgttactggaaatcttacgtaattttgggaatttttacatta
attgaggaaggcaccaaagtaattcagcccatatttttggggaaagttattaattatttt
gaaagttatgatcccagcgattctgtggctttgcacacagcttatggctatgccacagtg
ctgactgtctgcacgctctttttggccatcttgcatcacctgtatttctatcacgttcag
tgcgctggaatgaggttaagagtagccatgtgtcatatgatttacaagaaggcacttcgt
cttagcaacatggccatggggaagacaaccacgggccagatagtcaacctgctgtccaat
gatgtaaacaaatttgatcaggtgacaatctttttacactttctgtgggctggaccactg
caggctgttgcagtgactgttctgctctggatggagataggaatatcatgtctggctggg
atggcagttctcattatccttctgcctttgcagagctgcatcgggaagttgttctcatcg
ctacggagcaagacagcagcttttacggatgccaggatcaggaccatgaatgaggttata
actggcataaggataataaaaatgtatgcttgggaaaagtcctttgcagatctcattgcc
agtttgagaaggaaggaaatttccaaggttctgaaaagttcctacctcagagggatgaat
ttagcatcatttttcgttgcaaacaaaatcatcctgttcgtgaccttcaccacctacgtg
ttgcttggcaatgtgatcacagccagccgtgtgtttgtggcaatgacgctgtatggcgct
gtgcggttgacagtcaccctcttcttccctgcagccattgaaagagtgtcagaggcaatt
gtcagcattcgaagaatccagaacttcctggtacttgacgaggtatcacggcgcacaccc
cagcccccatcagatggtaaagcgttagtacacgtgcaggattttactgctttctgggac
aaggcattagaaactccaaccctacaaggtctctcctttactgtcagacctggtgaattg
ttagctgtggttggccctgtgggagcaggcaagtcgtcactgttgagcgctgtgcttggt
gagctacctccaagtcaggggctggtcagcgtgcatggaagaattgcctatgtttctcag
cagccttgggtgttctcaggaactgtgaggagtaatattttatttgggaagaaatatgag
aaggaacggtatgagaaagtaataaaggcttgtgctctgaaaaaggacttacagcttttg
gaggatggggacctgactgtgataggagatcgtggagccacattgagtggagggcagaaa
gcgcgggtgaatctcgcaagagcagtctatcaagacgctgacatctacctcctggacgac
ccgctcagcgcagtagatgcagaagttggcaagcacctgttccagctgtgcatttgtcaa
accttgcatgagaagatcacaattttagtgactcaccagttgcagtacctcaaagctgca
agccaaattttgatattgaaagatggtaaaatggtgcagaagggaacctacactgagttc
ctaaaatctggagtcgatttcggctcccttttgaagaaagaaaatgaggaagcggagcag
tctccagccccaggaactcccacgctgaggaaccggaccttctcagaatcttccgtgtgg
tcacagcagtcttccagactgtctttgaaagatggagctcaggaaggccaagatacagag
gatacaccagtagtgcaatcagaggcgagtcgttcagaaggaaaagttggttttaaggcc
tataagaattacttcacagctggtgcttcctggtttgtcatcattttcctcattctgcta
aacatagcagctcaggttgcctatgtccttcaggactggtggctttcctactgggcaaat
gaacaaagcagactgaataccactgtgaatggggaaggaaatacaacagagaagctagat
cttacctggtacttaggcatttatggaggtttaactggagccactgtcctcttcggcata
gcaaggtcactgttggtattccacgtccttgttaattcttcacaaactttgcacaacaag
atgtttgagtcaatcctgagagctccagtgttgttctttgatagaaatccaataggaaga
attttaaatcgtttctccaaagacattggacatatggatgacttgcttcccctgacattt
ctagatttcatccagactttgctccttgtgatcagtgtggtagccattgcggccgccgtg
attccttggattgcaatacccttggttcctcttgccatcattttcttggttcttcggcga
tatttcttagaaacatcaagggatgtcaaacgcctggaatctacaacacggagtccggta
ttttcccatttatcctcttccctccaggggctctggaccatccgagcatacagagctgaa
gacaggtgtcaggagctatttgatgcacaccaggacttacattcagaggcttggttcttg
tttttgacaacatctcgatggttcgctgtgcgtctggatgccatctgtgccatctttgtc
atcgttgttgcctttgggtccctcattctggccaaaactttggatggtggacaggttggc
ctggctttatcctatgccctcacgcttatggggatgttccagtggtccgtgagacaaagt
gccgaagtagagaacatgatgatttccgtggagagggtgattgaatacactgacctggaa
aaagaagcaccttgggaataccagaaacgccctcccccagcctggccccacgaaggagtg
atcgtctttgataatgtgaacttcacatacagtttagatggacctctggtgttgaagcac
ctgacagcactcattaagtcaagggaaaaggttggaattgtgggaagaacaggagctgga
aaaagttccctcatctcggcccttttcagattgtcagaacctgaaggtaaaatttggatt
gataagatcttgacaagtgaaattggacttcatgatttaaggaagaaaatgtcaatcata
ccgcaggaacctgttttgttcactggaacaatgaggaagaacctggatcccttcaatgaa
cacacagatgaggaactgtggaatgctctgaaagaggtacaacttaaagaagccattgaa
gatcttcctggtaagatggatactgaattagcagaatcaggatccaattttagtgttgga
cagagacaattagtatgccttgccagggcaattctcaagaagaatcggatattgattatt
gatgaagcaacagcgaatgtggatccaaggttttggattcaggaagactga |
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