KEGG   Castor canadensis (American beaver): 109698840
Entry
109698840         CDS       T04791                                 
Symbol
Tpo
Name
(RefSeq) thyroid peroxidase
  KO
K00431  thyroid peroxidase [EC:1.11.1.8]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan00350  Tyrosine metabolism
ccan01100  Metabolic pathways
ccan04918  Thyroid hormone synthesis
ccan05320  Autoimmune thyroid disease
Module
ccan_M00043  Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    109698840 (Tpo)
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    109698840 (Tpo)
 09160 Human Diseases
  09163 Immune disease
   05320 Autoimmune thyroid disease
    109698840 (Tpo)
Enzymes [BR:ccan01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.8  iodide peroxidase
     109698840 (Tpo)
SSDB
Motif
Pfam: An_peroxidase EGF_CA Sushi EGF_3 FXa_inhibition cEGF Plasmod_Pvs28 D_CNTX
Other DBs
NCBI-GeneID: 109698840
NCBI-ProteinID: XP_020038853
UniProt: A0A8B7W4M0
LinkDB
Position
Unknown
AA seq 927 aa
MKMPTALAVMLAVASTGIFFAFILTAKELLWGKTGKSHVTSIVEASRLMVDNAFYSTMKR
NLKRREVASPAELLSFSKLPEPTSRAMSRAAEILETSIQTMKNKQSRHPTDVLSEELLNL
IANLSGCLPHMLPPKCPDTCLANKYRHITGACNNRDHPRWGASNTALARWLPPVYEDGFS
QPRGWNPTFLYNGFPLPPVREVTRHIIQVSNEAVTEDDQYSDFLTAWGQYIDHDIALTPQ
SASTTAFSGGADCLLTCENQNPCFPIQLPANSWPTAGAACLPFYRSSAACGTGDQGALLG
NLSAANSRQQMNSLTSFLDASTVYGSSAAAEKLLRNWTSAAGQLRVNARHRDAGRALLPF
GPPRAPAACAPPPAPSAPPPGAPRAPCFLAGDGRASEVPALAAVHTLWLREHNRLAAALK
ALNAHWSADNVYQEARKLVGALHQIITMRDYVPRILGPEAFGQYVGPYEGYDSTVNPTVS
NVFSTAAFRFGHATVHPLVRRLDADFQDHAGLPRLQLHDGFFSPWRLIQEGGVDPVVRGL
LARPAKLQVQEQLMNEDLTERLFVLSNSGTLDLASLNLQRGRDHGLPGYNEWREFCGLPR
LDTPADLSRAIANRSVVNKIMDLYKHPDNIDVWLGGLVENLLPRARTGPLFACLIGKQMK
ALRDGDRFWWENSLVFTEAQRRELKKHSLSRVICDNTGLTRVPVDAFHTAEFPQDFESCD
NIPSMDLEVWRETFQQDDKCGFPEEVDNGDFVHCDEAGQRVLVYSCHHGYELQGQEQVTC
TQDGWDFQPPVCKDVNECADPTHPPCHPSATCKNTKGSFQCVCTDPYVLAEDGRTCITPG
RLPRASWVSIVLGAILVGGLASLTWMVICRWTHSDTKATLPITGRDVSATAQSGCKKCLE
RRLTPPRAAARKAEQEPACGSQVLLCE
NT seq 2784 nt   +upstreamnt  +downstreamnt
atgaagatgcccacagccctggccgtcatgctggctgtggccagcaccggaatcttcttc
gctttcatcttgacagccaaagaactcctttggggaaagactgggaagtcccatgtcacc
agcatcgtggaagccagcaggctcatggtggacaatgccttctacagcaccatgaagaga
aacctcaagagaagggaagtcgcctccccagctgagcttctgtctttctccaaactcccc
gagccaaccagcagggccatgtcccgagctgcggagatcctggaaacctcaatacagaca
atgaaaaacaaacagtcccggcaccccacagatgtcctatcagaagagctcctgaacctg
attgccaacttgtctggatgcctacctcacatgctgccaccaaagtgtcccgacacttgc
ctggcgaacaagtacagacacatcactggggcatgcaacaacagggaccatcctaggtgg
ggagcctccaatacagccctggccagatggctccctccagtctacgaagatggcttcagt
cagcccagaggctggaaccccaccttcttgtacaatgggtttccactgcccccggtgcgg
gaggtgacaaggcacattattcaagtttctaacgaggcggtgacagaagacgaccagtat
tctgacttcctgacagcgtggggacagtacatcgatcacgacattgctctcacaccacag
agcgccagcaccaccgccttctcggggggagccgactgcctgctgacgtgtgagaaccaa
aacccatgcttccccatacagctccccgcgaactcgtggccgacggcgggcgccgcgtgc
ctgcccttctaccgctcgtccgccgcctgcggcaccggggaccagggcgcgctcctcggg
aacctgtcggccgccaactcccggcagcagatgaacagcctgacctccttcctggacgcg
tccaccgtgtacggcagctccgcggccgccgagaagctgctgcgcaactggaccagcgcg
gcggggcagctgcgggtcaacgcgcgccatcgcgacgccggccgcgccctcctgcccttc
gggccgccgcgcgcgcccgccgcctgcgcgcccccgcccgcccccagcgcgcccccgccc
ggagccccgcgcgcgccctgcttcctggccggcgacggccgcgccagcgaggtccccgcc
ctggcggccgtgcacacgctgtggctgcgcgagcacaaccgcctggccgccgcgctcaag
gccctcaacgcgcactggagcgcggacaacgtctaccaggaggcgcgcaagctggtgggc
gccctgcaccagatcatcaccatgagggactatgttcccaggatcctgggccccgaggcc
ttcggacagtatgtggggccctatgagggttatgacagcacagtgaatcctacggtgtcc
aacgtcttctctacggccgccttccgcttcggccatgccacggtccacccgctggtgagg
cggctggacgcagacttccaggaccatgctgggctccccaggctgcagctgcatgatggc
ttcttcagcccctggaggctcatccaggaaggtggtgtggacccagtggtcagaggcctc
ctagccaggccagccaagctgcaggtgcaggagcagttgatgaacgaggacctgaccgag
cggctcttcgtgctgtccaactcgggcaccttggacctggcatcactgaacctgcagcgg
ggccgggaccatggcctaccaggctacaatgaatggagagagttctgtggcctgccacgg
ctggacaccccagctgacctgagcagggccatcgccaacaggagcgtggtcaacaagata
atggacttgtacaagcatccagacaatatcgacgtgtggctgggcggcttggttgaaaac
ctcctgccaagggcccggacaggtcctctgttcgcatgcctcattgggaagcagatgaag
gccctgagggatggggacaggttttggtgggaaaacagcctggtcttcacagaagcacag
aggcgggagctgaaaaagcactcactgtctcgagtcatctgtgacaacaccggcctcacc
agggtccctgtggatgccttccacactgcagaattcccccaggactttgagtcctgtgac
aacatcccaagcatggacctcgaggtgtggcgggagacctttcagcaagatgacaagtgt
ggcttcccggaggaagtggacaatggggactttgtgcactgtgatgaggctgggcagcgc
gtgctggtatattcctgtcaccatggatacgagctccaagggcaggagcaggtgacctgc
acccaagatggatgggatttccagcctccggtctgcaaagatgttaatgagtgtgcagac
ccgacccacccaccgtgccacccctccgctacgtgcaagaatactaaaggcagcttccag
tgtgtgtgcaccgacccctatgtgctggctgaggacgggaggacctgtattactcctggc
aggctgcctcgggcatcctgggtctccattgtgctgggtgcgattctcgttggaggtttg
gcgagcctcacctggatggtgatttgcaggtggacacactccgataccaaagccacactg
ccaatcactgggagagatgtaagtgcgactgcccagtcggggtgcaagaagtgtctggag
cggaggctgacaccgcccagggcagcagctcggaaagcagagcaggaacctgcctgcggg
tcccaggtcctgctctgcgagtag

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