KEGG   Castor canadensis (American beaver): 109698990
Entry
109698990         CDS       T04791                                 
Symbol
Map2k6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan04010  MAPK signaling pathway
ccan04015  Rap1 signaling pathway
ccan04218  Cellular senescence
ccan04380  Osteoclast differentiation
ccan04620  Toll-like receptor signaling pathway
ccan04664  Fc epsilon RI signaling pathway
ccan04668  TNF signaling pathway
ccan04750  Inflammatory mediator regulation of TRP channels
ccan04912  GnRH signaling pathway
ccan04935  Growth hormone synthesis, secretion and action
ccan04936  Alcoholic liver disease
ccan05014  Amyotrophic lateral sclerosis
ccan05022  Pathways of neurodegeneration - multiple diseases
ccan05132  Salmonella infection
ccan05135  Yersinia infection
ccan05145  Toxoplasmosis
ccan05161  Hepatitis B
ccan05163  Human cytomegalovirus infection
ccan05167  Kaposi sarcoma-associated herpesvirus infection
ccan05169  Epstein-Barr virus infection
ccan05170  Human immunodeficiency virus 1 infection
ccan05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ccan05417  Lipid and atherosclerosis
ccan05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109698990 (Map2k6)
   04015 Rap1 signaling pathway
    109698990 (Map2k6)
   04668 TNF signaling pathway
    109698990 (Map2k6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    109698990 (Map2k6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    109698990 (Map2k6)
   04664 Fc epsilon RI signaling pathway
    109698990 (Map2k6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    109698990 (Map2k6)
   04935 Growth hormone synthesis, secretion and action
    109698990 (Map2k6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    109698990 (Map2k6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    109698990 (Map2k6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    109698990 (Map2k6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    109698990 (Map2k6)
   05161 Hepatitis B
    109698990 (Map2k6)
   05163 Human cytomegalovirus infection
    109698990 (Map2k6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    109698990 (Map2k6)
   05169 Epstein-Barr virus infection
    109698990 (Map2k6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    109698990 (Map2k6)
   05135 Yersinia infection
    109698990 (Map2k6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    109698990 (Map2k6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    109698990 (Map2k6)
   05022 Pathways of neurodegeneration - multiple diseases
    109698990 (Map2k6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109698990 (Map2k6)
   05418 Fluid shear stress and atherosclerosis
    109698990 (Map2k6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109698990 (Map2k6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccan01001]
    109698990 (Map2k6)
Enzymes [BR:ccan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     109698990 (Map2k6)
Protein kinases [BR:ccan01001]
 Serine/threonine kinases: STE group
  STE7 family
   109698990 (Map2k6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344
Other DBs
NCBI-GeneID: 109698990
NCBI-ProteinID: XP_020039043
UniProt: A0A250XYQ1
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINILGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaaaattccaaaagaagcattt
gaacaacctcagaccagttcaacgccacctcgagatttagattccaaggcttgcatttct
attggaaatcagaacttcgaggtgaaggcagatgacctggagcctatagtggagctggga
cgaggtgcgtacggggtggtggagaagatgcggcatgtgcccagcgggcagatcatggca
gtgaagaggatccgggccactgtaaatagccaggagcagaaaaggctattaatggatttg
gatgtttccatgaggacagttgactgtccatttacggtcaccttttatggcgcactcttc
cgagagggcgatgtttggatctgcatggagctcatggatacgtcattagataaattctac
aaacaagttattgataaaggccaaacgattccagaggatatcctagggaagatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctctctgtcattcatcgagacgtc
aagccttcgaatgtgctgattaatattctgggtcaagtgaagatgtgtgattttggaatt
agtggctacctggtggactctgttgctaaaacaattgatgcaggttgcaagccatacatg
gcccctgaaagaataaacccagagctcaaccagaagggctacagcgtgaagtctgacatc
tggagtctgggcatcaccatgattgagctggctatccttcggtttccctatgattcatgg
ggaactcccttccagcagctcaaacaggtggtagaagagccatcaccacaactcccagca
gacaagttctcagcagagtttgttgactttacctcacaatgcttaaagaagaattccaaa
gaacggcctacatatccagagcttatgcaacatccatttttcaccctacatgaatccaaa
gcaacagatgtggcatcttttgtaaaactgattcttggagactaa

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