Castor canadensis (American beaver): 109701440
Help
Entry
109701440 CDS
T04791
Symbol
Bace1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
109701440 (Bace1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
ccan01002
]
109701440 (Bace1)
Enzymes [BR:
ccan01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
109701440 (Bace1)
Peptidases and inhibitors [BR:
ccan01002
]
Aspartic peptidases
Family A1: pepsin family
109701440 (Bace1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
109701440
NCBI-ProteinID:
XP_020042577
UniProt:
A0A8C0WV59
LinkDB
All DBs
Position
Unknown
AA seq
501 aa
AA seq
DB search
MAPALPWLLLWVGSGMLPAQGTQHGIRLPLRSGLAGPPLGLRLPRETDEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGTGFPLNQSEVLASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAQKRIGFAVSAC
HVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggccccagccctgccctggctcctgctgtgggtgggctccgggatgctgcctgcccaa
ggcacccagcacggcatccggctgcccctgcgcagcggcctggcggggccccctctgggg
ctgcggctgccccgggagaccgacgaggagccagaagagcccggccggagaggtagcttt
gtggagatggttgacaacctgaggggcaagtccggccaaggctactatgtggagatgacg
gtgggcagccccccacaaacgctcaacatcctggtggacacaggcagcagtaactttgca
gtgggggcggccccccaccctttcctgcatcgctactaccagagacagctgtccagcaca
taccgggacctccggaagggtgtatatgtgccctacacccagggcaagtgggagggggag
ctgggcaccgacctggtgagcatccctcatggccccaacgtcactgtgcgtgccaacatt
gctgccatcactgaatcggacaagttcttcattaatggctccaactgggaaggcatcctg
gggctggcctatgctgagatcgccaggcctgatgattctctggagcccttctttgactcc
ctggtgaagcagacccatgttcccaacctcttctccctgcagctctgtggcactggcttc
cctctcaaccagtctgaggtgctagcctctgttggagggagcatgatcattgggggtatc
gaccattcactgtacacaggcagtctctggtacacacccatccggcgggagtggtattat
gaggtgatcattgtgcgggtggaaatcaatggacaagatctgaaaatggactgcaaggag
tacaactacgacaaaagcatcgtggacagtggcaccaccaaccttcgtttgcccaagaaa
gtatttgaagctgcagtcaagtccatcaaggcagcctcctcgacagagaagttcccagat
gggttttggctgggggagcagctggtatgctggcaagcaggcaccaccccttggaacatt
ttcccagtcatctcactctacctcatgggtgaggtcaccaatcagtcctttcgcatcacc
atccttccacagcaatacctgaggccggtggaagatgtggccacgtcccaagacgactgt
tacaagtttgccatctcacagtcctccacgggcactgtcatgggagctgttatcatggag
ggcttctacgttgtctttgatcgggcccaaaaacgaattggctttgctgtcagtgcttgc
catgtgcacgatgagttcaggacggcagcagtggaaggcccttttgtcactctggacatg
gaagactgtggctacaacattccacagaccgatgagtcgaccctcatgaccatagcctat
gtgatggctgccatctgtgccctcttcatgctgccactctgcctcatggtgtgccagtgg
cgctgcctccgctgcctccgccatcagcacgatgactttgctgatgatatatccctgctg
aagtga
DBGET
integrated database retrieval system
