KEGG   Castor canadensis (American beaver): 109702281
Entry
109702281         CDS       T04791                                 
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan01521  EGFR tyrosine kinase inhibitor resistance
ccan01522  Endocrine resistance
ccan04012  ErbB signaling pathway
ccan04015  Rap1 signaling pathway
ccan04062  Chemokine signaling pathway
ccan04081  Hormone signaling
ccan04137  Mitophagy - animal
ccan04144  Endocytosis
ccan04360  Axon guidance
ccan04370  VEGF signaling pathway
ccan04510  Focal adhesion
ccan04517  IgSF CAM signaling
ccan04518  Integrin signaling
ccan04520  Adherens junction
ccan04530  Tight junction
ccan04540  Gap junction
ccan04611  Platelet activation
ccan04613  Neutrophil extracellular trap formation
ccan04625  C-type lectin receptor signaling pathway
ccan04727  GABAergic synapse
ccan04750  Inflammatory mediator regulation of TRP channels
ccan04810  Regulation of actin cytoskeleton
ccan04912  GnRH signaling pathway
ccan04915  Estrogen signaling pathway
ccan04917  Prolactin signaling pathway
ccan04919  Thyroid hormone signaling pathway
ccan04921  Oxytocin signaling pathway
ccan04926  Relaxin signaling pathway
ccan05100  Bacterial invasion of epithelial cells
ccan05135  Yersinia infection
ccan05152  Tuberculosis
ccan05161  Hepatitis B
ccan05163  Human cytomegalovirus infection
ccan05167  Kaposi sarcoma-associated herpesvirus infection
ccan05168  Herpes simplex virus 1 infection
ccan05203  Viral carcinogenesis
ccan05205  Proteoglycans in cancer
ccan05207  Chemical carcinogenesis - receptor activation
ccan05208  Chemical carcinogenesis - reactive oxygen species
ccan05219  Bladder cancer
ccan05417  Lipid and atherosclerosis
ccan05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    109702281
   04015 Rap1 signaling pathway
    109702281
   04370 VEGF signaling pathway
    109702281
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    109702281
   04517 IgSF CAM signaling
    109702281
   04518 Integrin signaling
    109702281
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    109702281
   04137 Mitophagy - animal
    109702281
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109702281
   04520 Adherens junction
    109702281
   04530 Tight junction
    109702281
   04540 Gap junction
    109702281
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109702281
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    109702281
   04613 Neutrophil extracellular trap formation
    109702281
   04625 C-type lectin receptor signaling pathway
    109702281
   04062 Chemokine signaling pathway
    109702281
  09152 Endocrine system
   04912 GnRH signaling pathway
    109702281
   04915 Estrogen signaling pathway
    109702281
   04917 Prolactin signaling pathway
    109702281
   04921 Oxytocin signaling pathway
    109702281
   04926 Relaxin signaling pathway
    109702281
   04919 Thyroid hormone signaling pathway
    109702281
  09156 Nervous system
   04727 GABAergic synapse
    109702281
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    109702281
  09158 Development and regeneration
   04360 Axon guidance
    109702281
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    109702281
   05207 Chemical carcinogenesis - receptor activation
    109702281
   05208 Chemical carcinogenesis - reactive oxygen species
    109702281
   05203 Viral carcinogenesis
    109702281
  09162 Cancer: specific types
   05219 Bladder cancer
    109702281
  09172 Infectious disease: viral
   05161 Hepatitis B
    109702281
   05168 Herpes simplex virus 1 infection
    109702281
   05163 Human cytomegalovirus infection
    109702281
   05167 Kaposi sarcoma-associated herpesvirus infection
    109702281
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    109702281
   05152 Tuberculosis
    109702281
   05100 Bacterial invasion of epithelial cells
    109702281
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109702281
   05418 Fluid shear stress and atherosclerosis
    109702281
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109702281
   01522 Endocrine resistance
    109702281
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccan01001]
    109702281
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccan04131]
    109702281
Enzymes [BR:ccan01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     109702281
Protein kinases [BR:ccan01001]
 Non-receptor tyrosine kinases
  SRC family
   109702281
Membrane trafficking [BR:ccan04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    109702281
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    109702281
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    109702281
  Macropinocytosis
   Kinases
    109702281
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 SH3_10 Haspin_kinase DUF7063 SH3_3
Other DBs
NCBI-GeneID: 109702281
NCBI-ProteinID: XP_020043260
UniProt: A0A8B7WHZ7
LinkDB
Position
Unknown
AA seq 478 aa
AEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFRKGERLQIVNNTE
GDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNTENPRGTFLVR
ESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHAD
GLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIK
TLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETG
KYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNE
YTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGVLLTELTTKGRVPYPGMVNREVLDQV
ERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq 1437 nt   +upstreamnt  +downstreamnt
gccgagcccaagctcttcgggggcttcaattcctcggacactgtcacctccccgcagagg
gcggggccgctggccggcggagtgaccacctttgtggccctctatgactacgagtcacgg
acagagactgacctgtccttcaggaaaggggagcggctccagattgtcaacaacacggag
ggagactggtggctggcccactcgcttagcacgggacagaccggctacatccccagcaac
tacgtggctccttctgactccatccaggctgaagagtggtactttggcaagatcaccaga
cgggagtcagagcggttactgctcaacacagaaaaccctagagggaccttcttggtgcga
gaaagcgagaccacgaaaggtgcctactgcctctcagtgtcagactttgacaatgccaag
ggcctcaacgtgaagcactacaagatccggaagctggacagcgggggtttctacatcacc
tcgcgcacccagttcaacagcctgcagcagctggtggcctactattccaagcatgccgat
ggcctgtgccaccgtctcaccaccgtgtgccccacgtctaagccacagacccagggcctg
gccaaggacgcctgggagatcccccgggagtcgctgcggctggaggtcaagctgggccag
ggctgcttcggagaggtgtggatgggaacctggaatggcaccaccagggtggccatcaaa
accttgaagccgggcaccatgtctccagaggccttcttgcaggaggcccaggtcatgaag
aagctgaggcacgagaagctggtgcagctgtatgctgtggtgtcggaggaacccatctac
attgtcacagagtacatgagcaaggggagtttgctggacttcctcaagggggaaaccggc
aagtacttgcgactgcctcagctggtggacatggctgcccagatcgcctctggcatggcc
tacgtggagcggatgaactacgtccaccgagacctacgcgccgccaacatcctggtcggg
gagaacttggtgtgcaaagtggctgacttcgggctggcccggctcatcgaggacaatgag
tacacggcccggcaaggtgccaaattcccgatcaagtggacagctcccgaagccgccctc
tacggccgcttcaccatcaagtcggacgtgtggtcctttggggtcctgctgaccgagctc
accaccaagggacgggtgccctaccctgggatggtgaaccgggaggtgctggaccaagtg
gagcggggctaccggatgccctgcccgccggagtgccccgagtccctgcatgacctcatg
tgccagtgctggcggaaggagcccgaggagcggcccaccttcgagtacctccaggccttt
ctggaggactacttcacgtccaccgagccgcagtaccagccgggggagaacctatag

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