Cyprinus carpio (common carp): 109113571 Help Entry 109113571         CDS       T05134                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism ccar  Cyprinus carpio (common carp) Pathway ccar04020   Calcium signaling pathway ccar04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:ccar00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     109113571 (ryr3)    04020 Calcium signaling pathway     109113571 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:ccar04040]     109113571 (ryr3) Ion channels [BR:ccar04040]  Voltage-gated cation channels   Ryanodine receptor    109113571 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 EF-hand_1 EF-hand_6 Ago_Mid Motif Other DBs NCBI-GeneID:  109113571 NCBI-ProteinID:  XP_042602899 Ensembl:  ENSCCRG00000033603 UniProt:  A0A9Q9XJC9 LinkDB All DBs Position B20:complement(17042727..17118503) Genome browser AA seq 4864 aa AA seqDB search MAEGGEGEDEVQFLRTDDEVVLQCVAAIQKENRKFCLTAEGLGNRLCYLEPTSEAKYFPP DLCICNFVLEQSLSVRALQEMLAGQSGEGNPDHEQWAAQGGGHRTLLYGHAILLRHSFSG MYLTCLKTSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVS SERYLHLSISNGSIQVDASFMQTLWNVQPTCSRSNMEVGFLLGGHVIRLFHGHDESLTIP GSEQSQEQQRVVNYETGKGGSKARSLWRLEPLRISWSGSHIRWGQPFRLRHLSTGHYLGQ TEDNGLILLDREKSDTTATAFCFRSSKEKIDSGPKRDIDGMGVAEIKYGDSVCFIMHVST GLWLSYQAPDAKSSRLGPLKRRAVLSLEGHMDDGLTLQLCQHEESRAARIIRNTTRLFTQ FIRGLDGLNGEKTTEVTLPVCEVLQTLDDLIVYFQQPDSELEHEEKQRQLRSLIKRQDLF KEEGMLTLVSHCIDRLNVYNSAAEFEELAGEEAGEAWKDILNLLYELLAALIRGNRTNCT QFSRKLDWLVSKLERLESSSGILEVLHCILIESPESLNIIQKAHIRSIISLLYKHGRNHK ILDVLCSLCVCNGVAVRANQNFICDHLLPRRDLLLQTRLINDVQSMRPNIFLGMSEGSAQ YKKWYFELIIDQVDHYVTSEPTHLRVGWATTKGYAPYPGGGEGWGGNGVGDDLYSYGFDG LHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNVDGFFF PVVSFSAGVKVRFLLGGRHGDFKFLPPAGYAPCYEALLPKEKMRVEPVKEYKRDLEGVRD LLGTTEFLSQASFIPVPVDTSQIVLPPHLENVRDKLAENIHELWGMNKIELGWMYGKIRD DNKRQHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVAQVNINAEDDLKKIKLPKN YMMANGYKPTPLDLSDVKLTPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNRRN PRLVPYALLDERTKKSNRDSLREAIRTLVGYGYFIDPPDQETAHIVEKEGIESIRLFRVE KTYAVKTGKWYFEFEALTGGDMRVGWARPGCRPDIELGLDDQSFVFDGYRGRRVHMGSHF FGRTWTKGDVVGCMINMEDKSMIFTLNGEIVITNKGSELCFADFETEDGFIPVCSLGLSQ IGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPEDHPHIEVT RIDGTVDTPPCLKVTHKTYGTQTSNDDMVCCRLSMPVEFHSGPRKITDINELIAEDQRAK KDDGGKTDYGSITKYFYSVRVFAGQDPSSVWVGWVTPDYHYYSKHFSLSTVRTVTVTLGD ERGRVHESVRRSNCYMVCAGDVVSGSAGRSNTDLEIGCSIDLASGLVSFTANGRDLPTAY QVEPNTKLFPAVFVQPTSPNLFQFEFPKIPDAMPLSSAIFKSLQRNPEPQCPPRLDVQTI VSVLWSRMPNTFLSVETARVSERHGWVVQCLEPLQMMAVHIPEENRCIDIMELSENEDLR QFHYHTLKLFCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGQLREGFYDVLISIHL ETGKEAHLMMNNEFIIPVTDETRSIRLFPDDSKRHSLPGVGLSTSLTTRLNFTPPYFISP KRDQPLFSPQIPLGILKEKAISMLTEAVQGGGAHIRDPVGGSVEYQFVPILKLISTLLIM GALTSEEVRTILLLIDPTVFGDGKEEEEQMAVVEQGAEKEEATSNEEKAVEAGEEESKEA KQSPKGLLEKSLPESVKRQMCELLHYFCDCELKQRIEAIVAFSDDFVSKLQYNQKFRYNE LMQALNMSAAVTAKKTREFRSPPQEQINMLLNFSAGDDCTCPEELQEELQSFHDDLRLHC GIPMEEEEEEQDTSLKGRLMSLVYKIKGRPQKTEEKPTEQEQAAPTNLKELISQTMVTWA QECKIQDPALVRSMFSLLRRQYDGIGELLRALRKSYTISAKSVGDAINLLASLGQIRSLL SVRMGEEEGQLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGGKDKEIAFP KMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLACPAMRGSTPLDVAASSVMDN NSLALALEEPDLEKVVTYLAGCGLQNCPMLIARGYPDIGWNPIEGERYLSFLRFAVFVNG ESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISEDPALDLPNLPEGAAP TIGEDEEEEEVAHMGNSIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSLVPTK DLVGIISIPLKMPVVNKDGTVTEPDMNASFCPEHKAPMVLFLDRVYGIDDQSFLMHLLEV GFLPDLRASASLDSEVLRSTETALAMNRYIGSAVLPLLTRCAHLFTHTEHYATLVDSTLH TIYRLSKGRSLTKAQRDAIDECLLAICMHLRPSMLQQLLRRLVFDVPQLSEYCKMPIKLL TNHYEQNWKYYCLPTGLGSYGMASEEELHLTKKLFWGLFDSLSQKKYDAELFKMAMPCLS AIAGAIPPDYVDSSPGSTLVKQASMDAQGNFDPQPISTANISLPEKLDYIASKFAEHSHE KWYSEKIALGWTAGDKVDDKAKTHPLLKAYKALSEKDRETYRYPVKETLKSMLAMGWNIE RTKEGEAMFQQRETEKQRKISESSQGEFIPAPQDLENVILSRELQAMVETVAENYHNIWA KKKKKELDSKGGGSHPLLVPYDTLTAKEKYRDREKAQELFKFLQVNGYAISRGLKDMEQD SSSMEKRIAYKFLKRLLNYVDSAQEFIAHLEALATSGKTEKSPHDQEIKFFAKVLLPLID LYFKNHCLYFLSSPNINLSSSGYASNKEKEMITSLFCKLAALVRHRITLFGSDSTTMVSC LHILSRSLDFRTVMKSGSELVKAGVRTFFENAAEDLEKTLENLKLGKLGQSRTQMKGVTQ IISYTSAALLPILTVLFQHITQHQFGAELLLDDIQLSCYRILTSLYSLGTGKNLYVEKQL PVLGECLSTLVGAMPVAFLEPHLNMHNPQSVFNTKTPRERAILSMPDTVDEMCPEMPNLD GLMKDIGDISESGARYTEMPQVIEVILPMLCNYLSYWWAKGPENSPVDTNCCTTVTSEHL SLILGNILKILNNNLGIDNAPWMKRLAVYSQPIISKASPDLLRMHFLPTLEKLKKKTVKV VAEEELLRAESRADTQEAELQILDEFAVLCRDLYAFYPMLIRYVDNNRSKWLKQPDSDST KLFKMVSEIFILWCKSHNFKREEQNFVVQNEINNLAFLTGDSKTKMSKSGGQDQERRGKR RRGELYSIQTSLIVAAHKKMLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKDYLRKNL HLQEKSADPAVQWQVNLYRDVVVKNEGPPDPEHNVERVQAISAAVYHLDQVEQPLRNKKM VFQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLSGYQSLWIETEEYSFEEKLVQDLA KTPMTVVEEEEEEEAEVHPDPLHQLILHFSHNALTERSFLEEDPLYIAYADMMAKSCAEN EEEEEEEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTGTLK LGISILNGGNVLVQQKMLDYLKEKRDAGFFKSLSGLMMSCSVLDLNAFERQNKAESLGMV TEEGSINMRERGSKVLQNDDFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIIST VDYLLRLQESISDFYWYYSGKDIMDEAGQLNFSKALAVAKQIFNSLTEYIQGPCIGNQQS LAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMVVMMLSLLEGNVVNGT IGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPDCKGIISKKEFQKSMDS QKQYTQSEIEFLLSCVEADENGMFNYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSH LSTFLNLAESVLSYFEPYLGRIEIMGGAKRIERVYFEISESSRTQWEKPQVKESKRQFIF DVVNEGGESEKMELFVNFCEDTIFEMQLASQISEPDAAERPAEDEDEELHSLLEGLSEEE DSPLESASAFTAACASVKKSMSNFRKMLTFKNMRKQFKKFRKLTIREMITGFFSFFWMLF TGFFKGIFAIIFGFFHIIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVMEAEK SESSELVVSADMVQMTGAGAEKLEGDMIMDLLNPAAKKEGKHGAEPGLGDVCEVLSESSA PVEKKKSQKVAAEKPESEPEKADTENQEKEDKAKEETPEEPPAAKPAPKAKHGSGKEAAP AFMASFFARLEVYKAKMLNYLARNFYTLRLLALFMAFAINFILLFYKVTGEFDDEEEEGS WGGEEEEGDEDDEGMEYFILQESTGYMAPTLTFLALLHTVVSLLCVVGYYCLKVPLVVFK REKEIARKLEFDGLYITEQPSDDDIKGQWDRLVIATPSFPNNYWDKFVKRKVINKYGDLY GAERIAELLGLDKSALDFDPTEEAVVKEASLLSWLSSIDTKYHIWKMGVVLTDNSYLYLI WYTIMSILGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTV VAFNFFRKFYNKSEDEDAPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPSELYR ILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPH GFETHTLQEHNLANYLFFLMYLINKDETEYTGQESYVWKMYQERCWDFFPAGDCFRKQYE DLLG NT seq 14595 nt NT seq  +upstreamnt  +downstreamnt atggccgaaggtggtgaaggggaagatgaggttcagttcttacgaactgatgatgaggtg gtactgcagtgtgtcgctgccattcagaaggagaatcgcaaattctgtcttacagcagag ggactcggcaaccgcctgtgttatctagagcccacatcagaggcgaagtattttcctcct gacctatgcatctgcaactttgtgctggagcagtcgctctcagtgcgggccctgcaggag atgcttgctgggcagagcggtgaagggaatcctgatcatgagcaatgggcagcacaggga ggtggacatcggacactgctctacggtcacgccatcctccttaggcattccttcagtgga atgtatcttacatgcctaaagacttccaggtctctgacagacaaactatcttttgatgtt ggccttcaagaggattcaactggggaagcttgttggtggacaattcacccggcatccaag cagaggtcagagggtgagaaggtgcgcattggagatgacctcatcttggtcagcgtgtcc tctgagaggtacctgcacctctccatttccaatggaagtattcaagtggatgcttcattc atgcaaacactgtggaacgttcagcctacctgctccagaagcaacatggaagtgggattt cttctgggtggacatgtgatacgcttgttccatgggcacgacgagagcctcaccatacca ggatccgagcaaagccaagagcaacagagagtggtgaactatgagaccggcaaaggaggg tccaaggccaggtctttatggagactggagcctcttcggataagctggagcgggagtcac atcagatggggtcagccattccgcctccgccatctctccaccggtcactacctgggccag acagaggacaatggcctgatactactggacagagagaagtctgacaccactgcaacagcc ttctgtttccggtcaagcaaggaaaagattgactctggcccaaagcgtgatattgatggt atgggagttgcagagatcaaatacggcgattcggtctgcttcatcatgcatgtgtccacg ggcctgtggttgtcctaccaggcgcctgatgccaaatcttctcgcctgggcccactgaag agaagggctgtcctgtctcttgagggccatatggatgacgggctgactctgcagctttgc cagcacgaggagtcccgggcggctcgcatcattcgtaataccactcgcctcttcactcag ttcatcaggggtctggatggtttaaatggggagaagactacagaggtgacactgcctgtg tgtgaagtgctgcagacactagacgacctcatcgtgtacttccagcagcctgactctgag ctcgaacatgaggagaaacagaggcagctccgatctctcatcaagcgccaagatctcttc aaagaagagggaatgctaaccctggtctcacattgcatcgatcgtcttaacgtgtacaac agtgccgctgagtttgaggagttagcaggcgaggaggccggagaggcctggaaggacatt ctcaacctcctctatgagcttctggccgctctgattcgaggcaacaggaccaactgcaca cagttctctcgcaagctggattggctggtcagcaagctagagagattggagtcctcatca ggcattttagaagtgcttcactgtatcctaatcgagagtccagaatctctgaacatcatc cagaaggcccacatcagatccattatttctctgctgtacaagcatggacgcaaccacaag attctagatgttctctgttccctgtgtgtctgcaatggtgtggctgtgagagccaatcag aacttcatctgtgaccacctgcttcccaggagagatctgctgctccagacacgattgatc aatgatgtccaaagtatgagacccaacatcttcctgggcatgagtgagggctcggcacaa tataagaaatggtactttgagctgatcatcgatcaagtagaccactatgtgaccagtgag cccacccaccttcgtgttggctgggccaccaccaaaggctacgccccctatcctgggggt ggagagggctggggaggaaatggtgtgggtgatgatctttactcctatggttttgacggg cttcatctgtggtcaggccgaatcccacgggccgtggcctctattaaccagcacttgctg aattcagacgatgttgtgagctgctgtctggatctcggagcccctagcatgtctttccga atcaatggtcagcccgttcaaggcatgtttgaagacttcaacgtagatggcttcttcttt cccgtcgtcagtttctctgcaggggtcaaggtgcgtttcttgttgggtggacgccatggc gactttaagttcctgcctccagccggctatgcaccatgttatgaagcactgctccccaaa gaaaagatgcgtgtggagcctgtgaaggagtataaaagagacctggagggagtgagagat ctgctgggcaccacggagttcctgtcccaggcttccttcattcctgttcctgttgacacc agccagattgttctgcctccacatcttgaaaatgtgcgggacaaattagctgagaacatc catgagctctggggcatgaacaaaatagagcttggctggatgtatggcaagatcagagat gacaacaagagacagcacccttgtcttgttgacttttctaaactgccagaaacagaaaag aattataacctgcagatgtcaactgaaactttgaagaccctgcttgctttgggatgccat gttgcacaagtcaatataaatgctgaagacgacctgaaaaaaattaaactccccaagaac tacatgatggcgaatggctataaacccacaccactagacctttctgatgtgaaactgaca cctggtcaagaggttctagttgataaattggctgaaaatgctcacaatgtttgggccaaa gatcgcatcaaacaaggatggacctatggtattcagcaggatttgaaaaaccgtcgtaat ccacggctggtgccatatgctttattagacgaacgcactaagaaatcaaaccgagacagt cttcgagaggccatccgtactctggttggatatggctattttatagacccacctgatcaa gagactgctcacattgtagagaaggagggcattgaatccatccgtctcttccgtgtggag aagacctatgctgtgaagacagggaagtggtattttgagtttgaggcgctcactggaggt gacatgcgggtgggctgggcacggcccggatgcagacctgatatagaactgggactagat gaccagtcctttgtctttgatggctacaggggccgccgggttcatatgggcagtcatttc tttgggaggacgtggactaaaggagatgtggtgggctgcatgatcaacatggaggacaaa tccatgatattcaccctgaatggagagatcgtaatcaccaacaagggctctgagctctgc tttgctgactttgaaactgaagatggattcattccagtgtgcagcctgggtctttcccaa attggccgcatgaatttaggaaaagacgctagtacttttaagtactacactatgtgtggc cttcaggaaggatttgaaccatttgctgttaacatgaatcgagaagtcaccatgtggttc agcaaacgcctgcctacgtttgttaatgtaccggaggaccacccccatattgaggttact agaatagatggaactgtggacacacctccatgtctaaaggtgacacacaagacatatggg acccagaccagtaatgacgacatggtctgctgtcgtctaagcatgcctgttgagttccac tctggccctcggaagatcactgatatcaatgagctgatcgctgaggaccaaagagccaag aaggatgatggaggcaagactgattatggcagcattacaaagtacttctactctgtgaga gtgtttgctggacaagatccatcatctgtttgggtgggctgggtgacaccagactaccac tactatagcaagcacttcagcctcagcacggttcgcactgtcactgtaacactgggagac gagcggggacgtgttcacgagagtgtgaggaggagtaattgttatatggtctgcgctggg gatgttgtcagcggctccgcaggccgtagtaacactgatctggagattggctgctccata gatctggcctcaggcctggtctcattcactgccaatggcagagatctgcctactgcatac caggttgagcctaacactaagctcttccctgctgtgtttgttcaacccacaagtcccaac ctcttccagtttgagtttcctaaaatcccagatgcaatgcccctgtcttcagccatcttt aagagtttacaaagaaacccagagccccagtgtcctcctcggctggatgtgcagacaatc gtgtccgtgttgtggagcagaatgcccaacaccttcctgtcagtggagacggcccgtgtg agtgagaggcatggctgggtggtgcagtgtctggagcccctgcagatgatggctgttcat atcccagaggagaacaggtgtatcgacatcatggaactatcagaaaacgaagatctacgg cagttccactatcacactttaaagctcttctgcgccctttgtgcattgggcaacactcgt gttgctcacgccctctgtagccatcttgaccaatcgcagctcctgtataccattgataac cagtacctgtctggtcaactgcgtgaaggcttttacgatgtcctcatcagcattcacctg gagacgggcaaagaggcccatctcatgatgaacaatgagtttataatcccagtaacggat gagacgaggagcatccgcctcttccctgacgactctaagcgtcactctcttcctggcgta ggcttgagcacttcactgaccactcgcctcaacttcacccctccgtatttcatcagcccc aagcgcgatcagcctctcttcagccctcagatccctcttggtatcctgaaggagaaagcc atcagtatgcttacggaagctgtgcagggcggaggcgcccacattcgagatcctgtgggc ggaagtgttgagtatcagtttgtgccgattctcaagctgatcagcaccctgctgataatg ggggcgctgaccagcgaggaggtgaggaccatcctgcttctcattgaccccactgtgttt ggggatgggaaggaggaggaggagcaaatggcagtggtggaacagggagcggagaaagag gaggccaccagtaatgaagagaaggctgtggaggcaggggaggaggagagtaaagaagcc aagcagtctcccaaaggtcttctagagaaaagcttgccagagtcggtcaaacggcagatg tgtgaactgctgcactatttctgtgactgtgagctgaagcagcgcattgaagctatagtg gccttctcagatgattttgtgtccaagctgcaatacaatcagaagttccgctacaacgag ttgatgcaagccctcaacatgtcagctgctgtcactgccaagaagacaagagagtttcga tcacctccccaagagcagataaacatgttgttgaacttcagtgctggtgatgattgcaca tgccccgaggagctgcaagaggagctccaaagcttccatgatgacctgcgactacactgt ggaatccctatggaagaggaagaggaggagcaggacacatctcttaaaggccgcctaatg tccctggtatacaagattaaaggtcgtccccaaaaaactgaggaaaaaccaacagagcaa gaacaggctgctcctacgaacctgaaggagctgatatctcagactatggtcacctgggct caggagtgcaagatccaagacccggcactggtccgcagcatgttcagccttttgagaagg cagtatgatggcatcggtgagctgctcagggccttgaggaagagctacaccatcagtgcc aagtctgtaggggacgcaataaacctgctggcctcgctgggccagatccgttcactgctt agcgtccgcatgggagaagaggagggtcagcttatgatcgacggcctgggggacatcatg aacaacaaagtgttttaccagcatccaaatctgatgcgtgttcttggcatgcatgagaca gtaatggaggtcatggtcaacgtgctgggaggaggcaaggataaggagattgccttcccc aagatggtggccagctgttgtcgcttcctttgctacttctgtcgcatcagccgtcagaac cagaaggctatgtttgaccacctgagctacctcctggagaacagcagtgtggggctggct tgccctgccatgagaggctctacacctttagatgtggctgcctcctctgtgatggacaac aacagtttagctctggcacttgaggaacctgatcttgagaaggtggtgacatatctggca ggctgtggcttacaaaactgcccaatgctcattgcaaggggatacccagacattggctgg aacccaatagaaggagaacgctatttatccttcctacggtttgctgtctttgtcaatggt gaaagtgttgaagagaacgctaatgtagtggtgaagcttttgatcaggcgtccggagtgc tttggacctgctctcagaggagagggagggcaaggtttactcgctgctatgaaggaagcc atcaagatctcagaagatcctgctttagacctgcctaacttacccgagggggctgcaccc accattggagaagatgaagaggaggaggaggtcgcccacatgggcaactctattatgtcc ttctactcagcccttattgatcttctgggccgctgtgcacctgagatgcatcttataaac aaaggcaaaggtgaagcactgcgtatccgtgccatcctccgttccttagttcccactaaa gatctggtgggaattatcagtattccactcaaaatgccggtcgtcaataaagatggcacc gtgacagagccagatatgaatgcaagcttctgtccggagcataaggcacccatggtgctt ttcctggaccgtgtctatggtattgacgaccagagctttttgatgcacctgctggaggtg ggcttcctgccagacctgcgagcatcagcctccctggactcggaggtgctcaggtccaca gagacagctctggccatgaaccgctatattggatctgcagtgcttcctctgttgacccgc tgtgctcatctgttcactcacactgagcactatgcaacgctcgttgactctacgctgcac accatctatcgcctctcaaagggccgatcactcaccaaggcccagagagatgctattgat gaatgtctactggccatttgcatgcatctgaggccatcaatgctacagcaacttttacgt cgtcttgtgtttgatgttccacagctttcagagtactgcaagatgcccattaagctgttg accaatcactatgagcagaactggaagtactactgtctgccaacaggcctgggcagctat ggaatggcatcagaggaggaactccacctcaccaaaaaactcttctggggactttttgat tctctttctcaaaagaaatatgatgcagagcttttcaaaatggccatgccatgtctgagt gccatagctggtgccataccacctgattatgttgactccagcccaggttccacattagtt aagcaggcctctatggatgcacaaggcaacttcgacccccagcctataagcacagcaaac atctcactgcctgaaaagctagattacatagcaagcaagtttgctgagcattcccatgag aaatggtactctgagaagattgctctcggctggactgcaggagataaagtagatgacaaa gctaaaactcatccacttctgaaagcgtacaaagcactgagtgaaaaggacagggagact taccgctatcctgtgaaagagactctgaagagcatgttggcaatgggatggaacattgag aggaccaaagaaggagaggccatgttccagcaaagggaaacagaaaaacagcgcaagata tcagagtcctctcagggtgagtttattccagccccacaagatttggaaaatgttattcta tcaagagaactacaggcaatggttgaaacagttgcagaaaattaccacaacatttgggca aagaagaagaaaaaggaacttgacagtaaaggaggaggaagtcatccattgttggtaccg tacgacacactgacggcaaaggagaagtacagagatcgagagaaggcccaagaactcttt aaattcctgcaggtcaatggatatgccatcagcaggggtctgaaggacatggagcaggat tcctcttctatggaaaagaggattgcctataagttcctcaagaggctcttgaattatgta gattctgcacaggagtttatcgcccatcttgaggctttggctactagtgggaagacagaa aaatctccccatgatcaagagatcaagttctttgctaaggttctgctgcccctcatagac ctgtacttcaaaaaccactgcttgtacttcctttcatctcccaatatcaacctgagcagc agtggctacgcatctaacaaagagaaggagatgatcaccagtctattctgtaagctggca gcccttgtcagacataggataacactctttggaagtgactccaccaccatggtgagctgc ttgcacatcctgtcacgctcactggacttcaggactgtgatgaagtctggctcagagctg gtgaaggctggtgtcaggacattctttgagaatgcagcagaagacctggagaagacactg gagaacttgaagctggggaagttgggtcagtcacgcacccagatgaagggcgttacccag atcatcagctacacctcagcggccctgctgcccatcctgacagttctctttcagcatatc acccaacaccagtttggagcagagctgctattggatgacattcagctgtcctgctaccgc atactgaccagcctctactctttgggcaccggcaagaacctctacgtggaaaaacagctt ccggtgctgggtgaatgtttatccacactggttggagccatgcctgttgccttcctggaa ccccacctaaatatgcacaacccccaatctgtcttcaacaccaagacaccaagagaacga gctattttgagcatgccagacactgtggatgagatgtgtcctgagatgcccaatctggac ggcctgatgaaggacattggcgacatttctgaatccggagcacgctacacagagatgccg caggtcatcgaggtcatcctgcccatgttgtgtaactacctgtcttactggtgggcaaaa ggcccagaaaactccccagttgataccaattgctgcacaactgtcacatctgagcatctc agcctaatcctgggcaatatccttaagattctcaataacaaccttggcattgataacgcc ccttggatgaaaagacttgcagtatatagccagcctatcattagcaaagctagcccagat cttcttagaatgcacttcctgccaacacttgagaaactgaagaagaaaacagtgaaggta gttgctgaagaggagctgctgagggctgaaagcagggcagacactcaggaagctgaactg cagattctggatgaatttgctgttctctgcagggatctgtatgccttctatccaatgctc attcgttatgtggacaacaacagatccaaatggctgaagcaaccagattcagattcaact aaacttttcaaaatggtgtcagagattttcatcctttggtgtaaatctcataactttaaa agggaagagcaaaattttgtggtgcaaaatgaaattaacaacctggcgttcctcactgga gacagcaagacgaagatgtcaaagtctggaggtcaggaccaagagagaagaggaaaaagg agaagaggagagttgtactccatccagacttcccttatcgtagcagctcacaagaagatg ttgcccattggtctgaacatgtgcactcctggagaccaggagctcatttcccttgccaag atccgttatagtctgaaagacacagatgatgaggttaaggattacctgaggaagaacctc catcttcaggagaagtcagcagatccagcagtgcagtggcaggtgaacctctacagagat gttgtggtgaagaatgagggacctccagacccagagcataatgtggagagagttcaggcc atctccgctgctgtctaccaccttgatcaggttgaacagccgctgaggaacaagaagatg gtgtttcaaaagctgctgtcaaagcaaagaaagcgtgccgtggtggcctgtttccgcatg gcaccactctacaacttaccaaggcatcgctcaattaacctcttcctcagtggctatcag agtctttggatagagacagaggagtactcctttgaggagaagctagtgcaggacctggca aaaactcccatgactgtggtagaggaagaagaggaagaagaagccgaagttcacccagac cctcttcatcagctcatccttcacttcagtcacaatgctctgacggagagaagttttcta gaagaggatcctctctacattgcatatgctgacatgatggcaaagagctgtgctgagaat gaggaagaagaagaggaagaggagggaaaagaaaaaacttttgaggaaaaagaaatggag aagcagaagattctgtaccagcaggccagacttcacgctcgaggggctgctgagatggtg ctacagatgatcagtgccagtaaaggccgacttggtcctatggtgactggcacccttaaa ctgggcatttctatcctaaatggaggcaacgttcttgtccagcagaaaatgctggattat ttgaaggaaaaacgagatgcgggcttctttaaaagtttatctggactaatgatgtcttgc agtgtgctggatttaaatgcatttgaaaggcaaaataaggcagagagtctaggaatggtg actgaagaagggtcaatcaacatgagagagcggggttccaaagtactacaaaatgatgac tttacaaaggatctgtttaggtttttgcaacttctatgcgaggggcacaataatgatttc caaaacttcttgcggacccagactggaaacactactacagtcaacatcatcattagcact gtggactacctattacgtctacaggaatctataagtgatttctactggtattactctggg aaagatatcatggatgaggctgggcaactgaacttctccaaagctttggcagtagccaaa caaatctttaactcactcactgagtacattcagggcccttgtatagggaatcagcaaagt ttggcacacagcaggttgtgggatgcagtggtcgggttcctgcatgttttcgccaacatg caaatgaaactgtcacaggattctagtcaaatcgagttattgaaagagctgatggatttg cagaaagatatggtggtcatgatgttatctcttttggaaggtaatgtggtgaatggaact attggcaagcagatggttgacacattagtggagtcctccagcaatgtggaaatgatcctt aagttcttcgacatgttcctcaaactgaaggacctcactacatctgataacttcaaggag tacgacccagattgcaaaggcattatatccaagaaggagttccagaagtctatggatagc caaaagcaatacacacagtctgagatcgagtttctcctctcctgtgtggaggctgatgaa aatggtatgttcaactacaaggagtttgtggaacgcttccatgaaccagccaaggacatc ggcttcaacgttgctgtgcttctcactaacctttcagaacacatgcctcacgactcacac ctgtccaccttcttaaacctggctgaaagcgttctcagttactttgagccatacctgggc cgtattgagatcatggggggtgccaagaggattgagagggtctactttgagatcagcgag tctagcagaacccaatgggaaaagcctcaggtcaaagagtccaaacggcaattcatcttc gatgtggtcaacgaaggcggtgagagtgagaagatggagttatttgtgaacttctgtgaa gacactatctttgagatgcagttggcctctcagatctctgagccagatgctgcagaacgt cctgcggaggacgaagacgaggagttgcatagtctgcttgaaggattgtctgaggaggaa gactcacctcttgagtccgcctcagccttcactgcagcctgtgcttctgtgaagaagagc atgtctaatttccgtaaaatgctgacgtttaagaatatgaggaaacagtttaaaaaattc aggaaacttaccatcagggaaatgatcacagggttcttctccttcttctggatgctcttc accgggttcttcaaaggcattttcgccatcatcttcgggttctttcatattatttggtcc tccatgtttggagggggtcttgtggagggtgctaaaaacatgaaagtgacagatatcttg ggtaacatgccggatccaacacagtttgggatccatggtgacgtaatggaagcagaaaaa tccgagagcagcgaattggtggtgtctgcagatatggtgcagatgactggggctggtgct gagaagctggaaggggatatgatcatggatctacttaatccagctgcgaagaaggagggg aagcatggggcagaacctggtctgggtgatgtctgtgaagtcctgtcagaatctagcgcc cctgttgagaaaaagaagagccagaaagtagcagcagagaagccagaatccgagccagag aaagcggacactgagaatcaagagaaagaagacaaggctaaagaggaaactcctgaggaa ccaccagcagcaaaaccagctccaaaagctaaacatggctcaggaaaggaagcagcccca gcatttatggccagcttctttgcaaggcttgaagtctacaaagccaaaatgctgaactac ctggctcgcaatttctacacccttcgtcttctggccttgtttatggcctttgccatcaac ttcatcctgctcttctacaaggtgactggagaattcgatgatgaggaagaggagggatcc tggggtggtgaagaggaggaaggtgatgaagatgatgaaggaatggaatacttcattctt caggagagcactggctacatggcacccacattgacgtttttggctttactgcacacggtc gtctccttactgtgtgtcgttggatattactgccttaaggttcctttagtcgtgttcaag cgggagaaggagatcgccaggaagcttgagtttgatggtttgtatattacagagcagccg tccgatgatgacatcaaaggacagtgggatcgtttggtcattgcaactccgtccttccct aacaattactgggacaaatttgttaagaggaaggtcatcaataaatatggtgacttgtat ggtgccgagcgcatagctgaactcctgggtctggataagagtgctctggacttcgatccc actgaagaggccgtggtgaaggaggcctccctgctgtcctggttgagctcaattgatacc aagtaccacatctggaaaatgggggtggtgctgacagacaactcttacctctacctgatc tggtacaccatcatgtctattctgggacattacaataacttcttctttgccgctcatttg ctggacattgccatgggtgtcaagacactgaggaccatcctttcttctgtgactcacaat ggcaaacagctggtattgactgtgggcctcctggcagttgtggtctacctgtacaccgtg gtggcttttaacttcttccgcaagttctacaacaagagtgaagatgaggacgcacctgac atgaagtgtgatgatatgatgacttgctacctgttccacatgtacgtgggtgtgagagct ggcggtggcatcggtgatgaaatcgaggacccggctggtgacccgtctgagctctaccgt attctgtttgacatcaccttcttcttctttgtcatcgtcattctgctggccatcattcag ggtttgatcattgatgccttcggtgagttgagagaccagcaggagcaggtgaaagaggac atggagacaaaatgcttcatctgtggaattgggaatgactattttgacacaaccccacac ggctttgagacccataccttacaagagcacaatcttgccaactatttattctttctgatg tatctcatcaacaaagatgagactgaatacactggtcaggagtcgtatgtttggaagatg tatcaggagagatgctgggatttcttccctgctggagactgtttccggaagcaatacgag gacctgctgggctag

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