KEGG   Caretta caretta (Loggerhead turtle): 125626753
Entry
125626753         CDS       T09292                                 
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
ccay  Caretta caretta (Loggerhead turtle)
Pathway
ccay04010  MAPK signaling pathway
ccay04012  ErbB signaling pathway
ccay04020  Calcium signaling pathway
ccay04510  Focal adhesion
ccay04520  Adherens junction
ccay04530  Tight junction
Brite
KEGG Orthology (KO) [BR:ccay00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125626753 (ERBB2)
   04012 ErbB signaling pathway
    125626753 (ERBB2)
   04020 Calcium signaling pathway
    125626753 (ERBB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    125626753 (ERBB2)
   04520 Adherens junction
    125626753 (ERBB2)
   04530 Tight junction
    125626753 (ERBB2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ccay01001]
    125626753 (ERBB2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ccay04147]
    125626753 (ERBB2)
   04090 CD molecules [BR:ccay04090]
    125626753 (ERBB2)
Enzymes [BR:ccay01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     125626753 (ERBB2)
Protein kinases [BR:ccay01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   125626753 (ERBB2)
Exosome [BR:ccay04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   125626753 (ERBB2)
CD molecules [BR:ccay04090]
 Proteins
  125626753 (ERBB2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Adeno_E3_CR2 ABC1 Protocadherin Haspin_kinase Tcell_CD4_C PDGLE EphA2_TM DUF2613
Other DBs
NCBI-GeneID: 125626753
NCBI-ProteinID: XP_048686093
LinkDB
Position
24:complement(3610873..3661995)
AA seq 1257 aa
MKKMILPSSCCFCMGLLLASFLPGCWSTEVCTGTDMKLLRPSSPENHYATLSRLYQDCQV
VQGNLEITYLGPDADMSFLKDIKEVQGYVLIAQNQVSRVQLESLRIIRGTQLYEEKYALA
VLANSDPTGTVGLQELGMRHLTEILKGGVHIEGNPQLCFQETILWGDIFHKNNDLAQHQQ
INSSRERTCAECRSFCSQGHCWGEGPQYCQTLTKSICDGCPRCKGTKPTDCCHEQCAAGC
TGPKHSDCLACLHVNRSGICELHCPPHFIYNSDIYQSVPNRDGRYTFGASCVSQCPYNYL
ATEVGSCTLVCPQDSQEVSTDSVQKCEKCSKPCPEGCYGLGVDFLKGVRAVNASNIQHFA
HCTKIFGSLAFLPETFAGDPATNTAPLKPEQLKSFGSLEELTGFLYIESWPETFPDLSIF
QNLRIIRGRVLHNGAYSLILQNLSIVSLGLRSLQEISSGMVLVHQNPNLCFLQKVPWEAI
FRNQRQTLFQTDNKPVEQCENEGLVCFRLCAKGQCWGPGPTQCVACERFLRGQECVESCN
LLDGAVREHVNGTRCLSCHPECLPQNGTETCNGSEADQCAACAHYRDAQYCVERCPSGVK
ADSSFVPIWKYPDEHGVCQLCPTNCSHSCMIRDEDGCPVDQKPSQVTSIIAGVVGALLAL
VLVLIIVVCIKRRKQQERKLAMRRLLQETELVEPLTPSGALPNQAQMRILKETELKKVKV
LGSGAFGTVYKGIWIPDGESVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRL
LGICLTSTVQLVTQLMPYGCLLDYVRENKDRIGSQDLLNWCVQIAKGMSYLEDVRLVHRD
LAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDV
WSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSEC
RPRFRELVTEFSRMARDPQRFVVIQNDDMMVPGSPIDSTFYRALLEEDDMQDLVDAEEYL
VPHQGFFNAEPSASYRSRIPSTRSTTESQVDAEETEDSAHYPYLGKALLEQSKGPTPDMF
DRDYVASKPLQSPPVREASTLQRYSEDPTSVSSDKNEGPESESYISPSSCSTAPEYVNQM
EDCLSPSKHQRSQVSTLEKPKGHLGKNGLIKEPKNPFQGSFANAVENPEYLTPHNLSLAS
AFTQAFDNPYYWNQDPSKVNPAEPGSTTNGFTTTPTAENPEYLGLTASIPPPKDTSD
NT seq 3774 nt   +upstreamnt  +downstreamnt
atgaaaaagatgatccttcccagcagctgctgtttctgcatggggctgcttttagcctct
ttcttgccgggctgctggagcacagaagtctgcacgggcaccgacatgaagctcctgcgt
ccctccagcccagaaaaccactacgccaccctcagccgcctctaccaggactgccaggtg
gtgcagggcaacctggagatcacctacctggggccagacgctgatatgtccttcctcaag
gatatcaaggaggtccagggctacgtgctgattgcgcagaaccaagtgagccgcgtgcag
ctggagagcctgcgcatcatccggggcacccagctctacgaggagaaatacgcgctggcc
gttctcgccaactccgaccccaccgggacggtggggctgcaggagctgggcatgaggcat
ctgacagagatcctgaagggcggggtgcacatcgagggcaacccccagctgtgtttccag
gagaccatcctgtggggcgacatcttccacaaaaacaacgacctggcccagcaccagcag
atcaacagcagcagggagaggacgtgtgctgaatgcagaagcttctgttcccaagggcac
tgctggggggaagggccgcagtactgccagacactgaccaaaagcatctgcgacgggtgc
cccaggtgcaagggcacgaagcccacggactgctgccacgagcaatgcgcagcgggctgc
actgggcccaagcactcggactgcctggcctgtctgcacgtcaaccgcagcgggatctgc
gagctgcactgcccgccccacttcatctacaactcggacatctaccagtcggtgcccaac
cgggacgggcgctacaccttcggagccagctgtgtcagccagtgcccctacaattacctg
gccacggaggtgggctcctgcacgctggtgtgtccccaggacagccaggaggtgagcacg
gacagcgtgcagaagtgcgagaagtgcagcaagccctgcccggaaggctgctatgggctg
ggcgtggatttcttgaagggcgtccgagccgtcaatgcctccaacatccagcactttgcc
cactgcaccaagatctttggcagcctggccttcctgcccgagaccttcgcgggggatccc
gccaccaacactgcacccttgaagccggagcagctcaagagcttcgggagcctggaggag
ctgacaggcttcttgtacatcgagtcctggccagagaccttcccagacctgagcatcttc
cagaacctccggatcatccgaggacgagtgcttcacaacggtgcctactccctgatactg
cagaacctgtccatcgtctcgctgggcctgcgctccctgcaggagatcagcagcgggatg
gtgctggtccaccagaaccccaacctctgcttcctccagaaggtgccctgggaagccatc
ttcaggaaccagcgccagacgctgttccagactgacaacaagcctgtggagcagtgtgag
aacgaggggctggtgtgcttccgtctctgcgccaaggggcagtgctgggggccgggcccc
acgcagtgcgtggcctgcgagcgcttcctgcgcgggcaggagtgcgtggagtcctgcaac
cttctggacggggccgtccgggaacatgtcaacgggacccgctgcctctcctgccaccct
gagtgcctgccccagaacggcacggagacctgcaacggatcggaggcggaccagtgcgcg
gcctgcgcccattacagagatgcccagtactgtgtggagaggtgcccgagtggggtgaag
gctgattcctcctttgtgcccatctggaagtatccggatgaacatggcgtctgccaattg
tgccccaccaactgcagccactcgtgcatgatccgggatgaagatggctgccccgtggat
cagaagccaagccaggtgacgtccatcatagccggcgtggttggcgccctcctggccctg
gtcttggtcctgatcatcgtcgtgtgcatcaagcggaggaagcagcaggagcggaagctc
gccatgcggcgcctcttgcaggagactgagctggtggagccgctgacgcccagcggggcc
ctccccaatcaagcccagatgcggatcctgaaggagaccgagctgaagaaagtgaaagtg
ttgggctccggggcctttggcaccgtgtataagggcatctggatccccgacggcgagagc
gtgaagatccccgtggccattaaagtcttgagagagaacacgtcgcccaaggccaacaag
gagatcctggacgaggcctacgtgatggcaggtgtgggcagcccctacgtctcccgcctc
ctgggcatctgcctcacctccacggtgcagctggtcacccagctcatgccctacggctgc
ctgctggactacgtgcgggagaacaaggaccgcatcggctcccaggacctgctcaactgg
tgtgtgcagatcgcaaaggggatgagctatctggaggacgtacggctggtgcaccgggac
ctggctgctcgcaacgtgctggtgaaaagccccaatcatgtgaaaatcactgactttggc
ctggcccggctgctggacatcgatgaaacagagtaccacgcggacgggggaaaggttccc
atcaagtggatggctctggagtccatcctgcgcaggagattcacgcaccagagtgacgtc
tggagctatggagtgaccgtctgggagctgatgacttttggtgccaagccgtacgatggg
atcccggcccgagagatccccgacctcctggagaagggagagcggctgccccagcctccc
atctgcaccatcgatgtctacatgatcatggtgaaatgttggatgatcgactcggagtgt
cgccccaggttccgggagctggtcacagagttctcccgtatggcgagggacccacagcgc
tttgtggtcatccagaatgacgacatgatggtgccgggcagtcccatagacagcaccttc
taccgcgccctgctggaagaggacgacatgcaggacttggtggatgctgaggagtacctg
gtccctcaccagggtttcttcaatgcagagccctctgccagctaccgcagccggatccct
tccaccaggagcacgacagagagccaggtggatgcagaggagacagaggactcggcccac
tatccgtacctgggcaaggctctcttggagcagtcgaagggccccactcccgacatgttt
gacagggactacgtggcaagcaaaccccttcagagcccgcctgtgcgggaggccagcacc
ctccagcgctacagcgaggaccccaccagcgtctcaagtgacaagaacgaggggccggaa
tcggagagctacattagcccgtcatcctgcagcacagctccagagtatgtgaaccagatg
gaggattgcctctcacctagcaagcaccaaagatcccaggtgtccacacttgagaagcca
aagggacacctgggaaagaacgggctaatcaaggaaccaaagaaccctttccaaggcagc
ttcgccaatgccgtggagaatccagagtacctgaccccacacaacctttccttggcaagt
gctttcacgcaggcctttgacaacccttactactggaaccaggacccttccaaagtcaat
cctgccgaaccaggctccacaaccaatggcttcaccacgactccgactgccgagaatcca
gagtatcttggcctcaccgcgtccatcccgccgcccaaggacacatcagattaa

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