Caretta caretta (Loggerhead turtle): 125630402
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Entry
125630402 CDS
T09292
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
ccay
Caretta caretta (Loggerhead turtle)
Brite
KEGG Orthology (KO) [BR:
ccay00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccay01001
]
125630402 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ccay04131
]
125630402 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ccay04147
]
125630402 (LRRK2)
Enzymes [BR:
ccay01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
125630402 (LRRK2)
Protein kinases [BR:
ccay01001
]
Serine/threonine kinases: TKL group
LRRK family
125630402 (LRRK2)
Membrane trafficking [BR:
ccay04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
125630402 (LRRK2)
Exosome [BR:
ccay04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
125630402 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_4
LRR_8
COR
Ras
Arf
LRR_9
Ank_2
LRR_13
AAA_16
T2SSE
GTP_EFTU
Gtr1_RagA
nSTAND3
AAA_22
NACHT
ABC_tran
LRR_NXF1-5
TrwB_AAD_bind
WD40_Prp19
MMR_HSR1
PduV-EutP
Beta-prop_EML_2
Kdo
AAA_7
G-alpha
AAA_29
AAA_23
FtsK_SpoIIIE
MobB
cobW
Septin
TniB
DUF3006
Arm
Motif
Other DBs
NCBI-GeneID:
125630402
NCBI-ProteinID:
XP_048692264
LinkDB
All DBs
Position
1:311114986..311225901
Genome browser
AA seq
2529 aa
AA seq
DB search
MASRGSCPEEEEREEAALRKLTVRLTNVQEGTPLESLLQTLEDLLALAHRPRAPRLFGGR
NVHVPVLLVLDSYPRVVALQQVGWSLFCKLIEVCPATLHNIAPQDVGKDWEVLGVHQHIL
KMLTIHNANRNLLIIGLKTLNLLLSSDIITIMLLDEETDVFLLVFDAMQTFPNNEEIQQY
GCKTLHMLFEKVPEEQLTEFVESKDHMILLNVLKQFQEKEDVVLPALYSLHSLAGPSSNV
EVLMSGNVRCYNVIAEMMKTFPNSEPIQEVSCCLLHKLTLGNFFNILVLNEVHEVIVKAV
IRYSENAKLQAAALSCLALLTETIFLNQDLEERKEEEEGEKLYWLEACYKALKLHRKNVD
VQEAACWALNNLLMYQCNLHKKIGDEDKQYPIHREAMLAMLMHSTAKEVFQAAANALATL
SEQNVSIRKVLLAKGIHINALDIMKKHSDSPEVAESACKMLNHVFEGSFPHLDIVMIVAS
EVIKAMRKHGKVPSVQLEALRVILPFMIPGATEERQNSSSGAVGDADLMLTLKVIKNQCL
LEGTHTLVLDALNRFIGNPGIQKCGLKILSSVVECSGALQMLSQQGATDTILHTLQMYPD
DQEIQCLGLSLLGSLITRKSLCIASMHVLATVLVSTLRRFKEVVEIQIHGFHMILTILDL
SPCFAKLLIYESFDTVIFYQMSMCFTEQRDRQFQSLCCKCFAKIANNDDLKNMMLEKACA
EYNSIMAECLLLLGADVNKNTKTSSLIYQVCEKGSNPKLVELLLTSGAREQDVRSALTVS
IKKGDSQIISLLLRKLSLDVANSSICLGGFCIGRIEPSWLSPLFPNKLTPIKKQTNAGSA
LARMVLGYQMKSFSEDRSRSSCNVTFSEDALDKSDDWIFMPELLVDSVFLLSDDIDSEGS
EGSFLMKKKYNSIAVADLYKDTPLQRYSPTLQRHSNSLGPGSDNEPLVKQRRKLSSDESH
KGISKFQSHLRRSDSLSSLVSEKEYIKSLDLSSNELENIDAISQNCCLTGHLERLEKLEL
HQNALTSIPEQLCETLKCLTYLDLHSNLFASFPTYLLKMNCIANLDISRNEIGPSLALDP
HSKCPSLKQLNLSYNQLSCIPKFLVDVAENLEQLMLEGNKISGICSPICLKKLKVLNISK
NNISSLAVNFLKECTKLEIFSARMNLLDTISNLPSSITSLKLSQNHFVSIPEAILLLPHL
RSVDLSNNKIINLPGPMHWKSLNLRELLFNYNQIDILDLNEKAYAWSRLEKLHLSHNKLK
EIPPQIGFLENLTSLDVSYNPGLSSFPDEMGKLSKVWDLPLDGLHLNLDFKHVGCKARDI
IRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKCKRSDLGTQNPTIGIDVKDWSV
PVKGKVKKDLILNVWDFAGQEEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNI
KARASSSPVILVGTHLDVSDEKQRKACLSKITRELLNKRGFPAIQDCHFVNATEESDAMI
KLRKTIIKESLNFKIRDQPVVGQLIPDSYLELEKIILFERENVPTEFPVIDYKRLLVLVQ
ESQLQLDENELPHAVYFLNESGVLLHFQDPALQLTDLYFVDPKWLCKIMAQILTVKVEGF
PKYPKGIVKRSDVEKFLLKKSRFPKIYMSQYFKLLEKFQIALPLGEDQLLVPSSLSDHRP
VIELPHCENSGIIIRLYEMPYFPMGFWSRLINRLLEVSPYMLSGRERALRPNRMYWRQGV
YLNWSPEAYCLVESAVFDSNPDSFLKITAPSCRKGCILLGQVVDHIDSLMEEWFPGLLDI
DVCGEGETLLKKWALCSFEDGKEHQKILLDDLLEKAEEGDLLVNPDQPRFTIPIAQIAPD
LILADLPRNIMLNNDELEFDQAPEFLLGDGGFGSVYRASYGGEEVAVKIFNKHTSLRLLR
QELAVLCHLHHPSLVSLLAAAIRPRMLVMELAPKGSLDRLLQQDSSSLTKTLQHRIALHV
ADGLRYLHSSMIIYRDLKPHNVLLFTLYPNSAVIAKIADYGIAQYCCRMGIKTSEGTPGF
RAPEVARGNVIYNQQADVYSFGLLLYDILTAGGRIIEGMKFPNEFDELAIHGKLPDPVKE
YGCAPWPEVESLISKCLKENPQERPTSAQVYDILNSAKLICLMRHISIRSAFAAECMVAA
NQSCKKAGVWIGTGNTKKGQVSFIDLNTDGHTCEDIADGRILCLALVTLPTEKENWILAG
TQFGSLWAFNTEDGKNKHHLQKMSDSVTCLYSNFFSKQSKQKNFFLVGTADGKIAVFEDQ
VVKYKGAAPLKILTIGNVSTPLTCLSESTCVSEKNIVWGGCGTKIILLSGDISIQTLIET
KTSQLFCHKAYSDANIISIAVDKSIYLAKKNSHFVEVWDKKTEKLCELIDCAHFLKEEVV
KLNKESKHTVAYSGRVKTICLQKNTALWIGTGGGHILLLDLSTRRPIRIIRDFCASVRVM
LTAQLGSLKNVMLVLGHCYKCDEDDKCQKELQSCMSVWDIKLPHEVQNLKKHIEVRQELA
EKMRRFSLD
NT seq
7590 nt
NT seq
+upstream
nt +downstream
nt
atggccagtcgcggcagctgccccgaggaggaggagagggaggaagccgccctgaggaaa
ctgaccgttcgcctcacgaacgtgcaggaggggacgccgctggagagcttgctgcagacg
ctggaggacctgctggccttggcccaccggccccgcgcgccccggctgttcggcggccga
aacgtccacgtgccggtgctgctggtgttggactcctacccgcgagtggtcgcgctgcag
caggtgggttggtcacttttttgtaaattaatagaagtgtgtccagccactctacataac
atagctcctcaggatgttggaaaggattgggaagtacttggtgttcatcagcatattctt
aaaatgcttactatccacaatgcaaacagaaacctcttgataataggactcaagacacta
aacctactactctcttcagatataattacaattatgctcttagatgaagagacagatgta
tttttgttggtgtttgatgctatgcaaaccttcccaaacaatgaagaaatccagcagtat
ggatgtaaaactttgcacatgctttttgagaaagttccagaagagcagctgactgaattt
gttgaaagcaaagatcacatgatcctactgaatgtgttaaaacagtttcaagaaaaagaa
gatgtagtacttccggcactttattctttacattcattagctggtccatccagcaatgtt
gaagtgctcatgtctggaaatgttagatgttacaatgtcatagcggaaatgatgaaaaca
tttcccaacagtgaaccaattcaggaagtgagttgctgtttgttgcacaagcttacactg
ggaaattttttcaacattctggtattaaatgaggtacatgaagtcattgtgaaggctgtt
ataagatactctgaaaatgcaaagttacaggctgcagcactcagttgtttagctctcctc
acggaaacaatatttttaaatcaagacttagaggaaagaaaagaagaggaagagggagaa
aaattatattggctggaagcatgctataaagcattaaaattgcaccgaaaaaacgtagat
gtacaggaggctgcctgttgggctttgaacaatctgttgatgtaccaatgcaaccttcat
aagaaaattggagatgaagataaacagtaccccatacacagagaagcaatgctagccatg
ctgatgcattccacagcaaaagaagtgtttcaggcagctgctaatgccttggcaacttta
tcagaacaaaatgtaagtattagaaaggttctgttggcaaaaggaatacacattaatgca
ttggacataatgaagaaacattcagactctcctgaagtggctgaaagtgcctgcaaaatg
ctgaatcatgtttttgaaggaagtttcccccatctggacatagtgatgatagttgcatca
gaagtcataaaggccatgaggaaacatggaaaggtgccatctgtacagctggaggccctt
cgagtcattttaccttttatgatccctggtgccacagaagaacggcaaaatagttcttca
ggagcagtgggagatgctgacttgatgcttaccttaaaagtaattaaaaaccagtgtttg
ttggaggggactcacacactagtgcttgatgctttgaacaggtttattggaaatcctggc
attcagaaatgtggattaaaaatactttcttctgtagtggagtgttctggtgcactacaa
atgttatcccagcaaggagccacagacactatacttcacacactacagatgtatccagat
gatcaagaaatacagtgcttaggtttgagtcttctaggatctttgattacaagaaagagt
ttatgtatcgcatctatgcatgtgctggcaacagttctggtttctactttacgacgattt
aaggaggtcgttgaaatacagatacacggatttcacatgatcttgacaatccttgacttg
tcaccttgttttgcaaagctgctgatatatgaatcatttgacacagtcattttttatcag
atgtccatgtgtttcactgaacaaagagaccggcagtttcaaagcttgtgctgtaaatgc
ttcgctaaaatagccaacaatgatgatttaaaaaacatgatgctggagaaagcatgtgct
gaatacaatagcattatggctgaatgtttacttttactaggagctgatgttaataagaac
acaaagacgagctctttaatctatcaggtttgtgagaaaggaagcaatcctaagctggtg
gaactactattaactagtggtgctcgagagcaggatgttcggagtgctttaacagtcagc
ataaagaaaggagatagccaaatcattagcttgctcttaaggaagcttagcctggatgtg
gccaacagcagtatatgtcttggaggattttgtattggaagaattgaaccttcctggctt
agccctttgttcccaaataaacttactcctataaaaaaacaaacaaatgcaggttctgca
ttggcaagaatggtgctcggataccaaatgaagagtttttcagaagaccgatcaagatcc
agttgtaatgtaactttctctgaagatgcactagataaaagtgatgattggatattcatg
cctgagctattagtagacagtgtttttctcttgagtgatgatatcgatagtgaagggagt
gaaggttcatttctgatgaaaaagaaatacaactccattgcagttgctgatctgtacaaa
gatacacccttacaaagatattctcctactttgcaaaggcattccaattctctgggacct
ggttcagataatgaaccattagtgaagcaaagaagaaaattgtcttcagatgaatctcac
aaagggatctcaaaattccagtcacatttaagacgatcagacagtttgtcttctttggtc
tctgagaaagaatatattaagtcattagatctttcatcaaatgagctggagaatatagat
gccatcagtcagaactgctgcttaactggtcacttggaacgtcttgagaaattggagctg
caccaaaatgcactcacaagcattccagaacaactgtgtgaaactttgaaatgtttgact
tacttggatttgcatagtaacctgtttgcatcttttcctacttatttactgaaaatgaat
tgtattgcaaaccttgatatctctcggaatgaaattggcccttccttagctttggatcca
catagcaaatgcccatctctaaagcagcttaatctatcatacaatcagctgtcatgcatt
cctaaatttcttgtggatgttgcagaaaacctggaacagttaatgctagaaggaaacaaa
atttcaggtatatgttcacccatatgcttgaagaaactgaaagttttaaacattagtaag
aacaatatttcatccctggctgttaattttctcaaggagtgcacaaaattggagatattt
agtgccaggatgaatttacttgataccatatctaacttgccatctagcataacaagttta
aaattatctcaaaatcattttgtcagtattccagaagcaattcttcttcttccacatttg
cgatcagtagacttaagcaacaataaaatcataaacctgcctggacctatgcactggaaa
tccttaaacttaagggagctcttgtttaactacaatcagatagacattttggacttgaat
gaaaaagcatatgcatggtctaggctagaaaagctacacctgtcccataacaagttaaag
gagattcctcctcagattggcttccttgaaaacttgacatctctggatgtaagttataat
cctggcttgagttcctttccagatgaaatgggaaagttgtccaaagtctgggatcttcct
ttggatgggcttcatcttaatttagatttcaaacatgttggatgcaaagccagagacatt
ataaggtttcttcagcagcggctaaagaaggctgtcccttataacagaatgaaactcatg
attgtgggaaatactggcagtggtaaaactacactgttacaacaactaatgaaatgcaag
cgatcagatttggggacacagaatcctacaataggcatagatgtaaaggactggtcagtt
ccagtgaaaggcaaagtgaagaaggatttgatattaaatgtctgggattttgcaggacaa
gaggagttctacagcactcatccccattttatgactcagagagccttgtatcttgctgtt
tatgatctcagcaaaggacaagcagaagtggatgctatgaagccgtggctgtttaatatc
aaggctcgagcttcatcatcccccgtgattcttgttggcactcatttagatgtctctgat
gagaaacaacgtaaggcctgtctgagtaaaattaccagagagctgttgaataaaaggggt
ttcccagcaatccaagattgtcattttgtaaatgctacagaagaatctgatgctatgatc
aaacttcggaaaaccataataaaggagagtctgaatttcaagatcagagaccagccagta
gtaggacagctaatcccagacagctatctggaacttgagaagataattttattcgaacgt
gaaaatgttccaactgaatttcctgtgattgactataagcgattattagtactggtgcaa
gaaagtcagttacagctggatgaaaatgaacttcctcatgcagtttactttctgaatgaa
tcaggcgtactgctacattttcaagacccagcactccagctaacagatctgtattttgtg
gaccctaagtggctgtgtaaaatcatggcacagattttgacagtgaaagtggaaggcttt
cctaaataccctaagggaattgtaaagcgttcagatgtggaaaaattccttttaaagaag
agcagattccctaagatctacatgtcacaatactttaagcttctggaaaagttccaaatt
gcattgccattaggagaagatcaactacttgttccaagcagtttgtctgatcacagacct
gttatagagcttccccactgtgaaaactcaggaatcatcattaggctgtatgagatgcca
tactttcccatgggattctggtccagactgatcaacaggttgcttgaagtgtctccttac
atgctctcaggaagagaacgagctcttcgtcctaatagaatgtattggagacaaggcgtt
tacctgaactggtctcctgaagcttactgtctagtggaatcagcagtatttgatagcaat
ccagacagttttttgaaaattacagctccttcttgcagaaaaggttgtatccttttgggg
caagttgtggatcacattgattctcttatggaagaatggtttccaggtttactggatata
gatgtatgtggtgaaggggaaactctgttgaagaaatgggctttgtgtagctttgaggat
ggcaaagagcaccaaaaaatattacttgatgatttacttgaaaaagctgaagaaggtgat
ctcttagtaaatccagatcaaccaagatttaccattccaatagcccagattgctcctgac
ctgatattggctgatttgcctagaaatatcatgttgaacaatgatgaattggaatttgac
caggctcctgaatttctgttgggtgacggtggttttggatctgtgtaccgcgcatcatat
ggtggagaagaagtagctgtaaagatttttaataaacatacctccctcagactcttacga
caagagcttgcagtgctttgtcatcttcatcaccctagcttagtatctttgctggctgct
gcaatccgtccccggatgttggtaatggaattagcccctaagggttctctggatcgttta
cttcagcaagatagttcaagcttaactaaaacacttcagcacaggatagctctacatgta
gcagatggtttaaggtatctacattcttcaatgatcatttatcgtgatttaaagcctcat
aatgtgctgctctttacattatatcccaattcagcagtcattgcaaagattgctgattat
ggcattgctcagtattgctgcagaatggggataaaaacctcagaaggtacaccaggattt
cgagcaccagaggttgccagaggaaatgttatttacaatcagcaagctgatgtatattca
tttggcttgcttctttatgacattttaacagcaggaggtagaataattgaaggcatgaag
tttccaaatgaatttgatgaattagcaattcatggaaaattaccagatcctgtcaaagaa
tatgggtgtgccccctggcctgaagttgaaagtttaatcagcaagtgtttgaaagaaaac
cctcaggaaagacctacatcggcccaggtttatgatattttgaactccgcaaagcttatc
tgtttgatgagacacatttcaatacgtagtgcctttgcagcagagtgcatggttgcagct
aatcaaagctgcaagaaggcaggggtctggatcggtactggaaatacaaaaaaaggacag
gtttcatttattgacttaaatacagatggccatacttgtgaggacattgcagatggaaga
atcttgtgtttggctttagtgactcttcctacagagaaagaaaactggattttggcagga
acccagtttggttctctgtgggcatttaatacagaagatggaaaaaacaaacaccatctt
cagaaaatgtccgattctgttacctgtttatacagcaactttttttcaaagcaaagcaaa
cagaagaatttttttctggtgggaacagctgatggcaaaatagcagtttttgaagaccaa
gtagtaaagtacaagggtgcggcacctttgaagatcttaactatagggaatgtcagcaca
ccacttacgtgcttaagtgaatccacatgtgtatctgaaaaaaatatagtctggggaggc
tgtggaacaaagatcatattattatctggtgatatatctattcaaaccctaattgagaca
aagacaagtcagctattctgtcacaaggcttacagtgacgcaaacattatttcaatagca
gtagacaaatccatctacttggctaagaaaaacagccattttgtggaagtttgggataag
aaaacagagaaactttgtgaactaattgactgtgcacattttctaaaggaagaagtagtg
aaactaaataaagaatcaaaacatacagtggcttattctggaagagtgaagaccatctgt
ctacaaaaaaatactgccctctggataggaacagggggaggacatatcctgctgcttgat
ttatcaacacgtcgtcctatacgaataatacgcgatttttgtgcctctgttcgagtcatg
ctgacagcccagctagggagcctcaagaatgtcatgctggttttggggcactgctataaa
tgtgatgaagacgacaaatgtcagaaagaactgcagtcgtgtatgtccgtgtgggacatt
aagctgccccatgaagtacaaaacctgaaaaagcacattgaagtgagacaggaattagca
gaaaaaatgagaaggttttctttggattaa
DBGET
integrated database retrieval system
