Caretta caretta (Loggerhead turtle): 125634377 Help Entry 125634377         CDS       T09292                                  Symbol MDN1 Name (RefSeq) midasin isoform X1   KO K14572   midasin Organism ccay  Caretta caretta (Loggerhead turtle) Pathway ccay03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:ccay00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     125634377 (MDN1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:ccay03009]     125634377 (MDN1) Ribosome biogenesis [BR:ccay03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     125634377 (MDN1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA AAA_16 AAA_3 AAA_7 AAA_22 nSTAND3 TsaE Sigma54_activ_2 AAA_14 ABC_tran Sigma54_activat AAA_6 AAA_18 AAA_25 MDN1_4th DUF815 PduV-EutP Gtr1_RagA Motif Other DBs NCBI-GeneID:  125634377 NCBI-ProteinID:  XP_048700966 LinkDB All DBs Position 3:138863082..139027212 Genome browser AA seq 5582 aa AA seqDB search MEALRLHLAGALQLVAQRNEKSSSELGRFLAKQIWTRQDRQCILNALAQLLVDKECTLLI GRQFRPILLDLLERNAEAINAGGQINHDLHERLCVAMSKLIGDHPDVLPFALRYFKDTSP VFQRLFLESSDANTVRYGRRRMKLRDLMEAAYLFLQQEQSVFRELWDWSVCVPLLRSHDT LVRWYTSNCLALVTCMNDEHKLSFLKKIFNPDELIRFRLKQLEESQMWNVERALVLANPD TSLWHREKGLQYTQGDIISGDLSANVIAVCGVVLPRQQLVPKEQESTIQNFVLVESTCMN LQNLAMAVAFQNPVLLEGPIGCGKTSLIEYLAVITGRMKPPHILKVQLGDQTDSKTLLGM YRCTDVPGEFVWQPGTLTQAVTKGHWILLEDIDYAPLDVISVLIPLLENEELLIPGRGDC LKVSPGFQFFATRRVFSCGGGWYRQQNSHATLLDKHWTKIRMDNMNKAELKEILQGRYPN LAAVTDRLLDIYIQLTGDKHQTTEISFPACEQGVEDTSEMRKENKRPNLEGRELSLRDLL NWCGRIAYNFDSSSSTTAVNIFQEALDCFTAMLSKQGSRQKMAEIIGSKLNISKKKAEFY CQLHKPEILTREHEVAVGRVRLLRKQTQALLIQREKQNFAATRPSSVLIEQLAMCVDKGE PVLLVGETGTGKTSTVQYLAHITGHHLRVINMNQQSDTADLLGGYKPVDNKLIWLPLRES FEELFSQTFSRKQNQTFLGHIQTCYRQKRWHDLLKLMQHVHKSAINKEAKENTSGSPLKE KWEAFGLRLNHAHQQMKMTENFLVFAFVEGTLAQAVKKGEWILLDEINLASAETLECLSG LLEGSSGSLVLLDRGDTEPLVRHPGFRLFACMNPATDVGKRNLPPGIRNRFTELYVEELQ NEGDLLILIMDYLKGLNVSKNTVQGIMNFYLSVRKETEAKLVDGTGHRPHYSLRTLCRAL RFAASNPCKNIQRSLYEGFCLGFLTQLDRVSHPIVQKLICQHIVSGNIKSLLKQPLPEPQ GGRAVQIEGYWISVGDKEPVIDETYVLTSSVKLNLKDIVRVVSAGTHPVLIQGETSVGKT SLIRWLAAASGNRCVRINNHEHTDIQEYIGCYTSDASGKLMFKEGVLIDAMRKGYWIILD ELNLAPTDVLEALNRLLDDNRELFITETQEVVRAHPRFMLFATQNPPGLYGGRKVLSRAF RNRFVELHFDELPSAELETILHKRCSLPPSYCSKLVKIMLNLQSYRRGSTVFAGKHGFIT LRDLFRWAERYRLAEQTEKDYDWLQHLANDGFMLLAGRVRKQEEVDVIQSVLEKHFKKKL YPHSLFSEESVRKLLVKSSTQMSVMDSEFSHVVWTQGMRRLAVLVGRALEFGEPVLLVGD TGCGKTTICQIFAALANQKLHSVNCHLHMETSDFLGGLRPVRQRSKDKEEFDSSRLFEWH DGPLVLAMKEDGFFLLDEISLADDSVLERLNSVLEVEKTLVLAEKGSQEDEDNEVELLIA GKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSNSREDLIQIVKHNLHPGLSLDRI NHQGTDIAELMMDFIEWLTNQEFGRQCILSVRDVLSWVNFMNVMVEDEEYSLFYISTVTS FVHAACLVYIDGIGSGTTSCSADTALSAREKCLKFLCEKLCTIVELTEYQKDELRIYYRT KEREFIWMENFIGVHPFFIPRGPVFQRNSVSDYALNAGTTAVNAQRLLRALQLNKPILLE GSPGVGKTSLVAALAKASGNCLVRINLSEQTDVTDLFGTDLPVEGGKGGEFAWRDGPLLA ALKGGHWIVLDELNLASQSVLEGLNACFDHRAEIYIPELGMSFHVQHKKTKIFGCQNPYR QGGGRKGLPKSFLNRFTQVYVDPLTAADMEFIGNTLFPAIDKNIIAKMVAFNNKIDQEVN ALKKWGQKGGPWEFNLRDLFRWCQLILVDQSPGCYDPGQHVFLVYGERMRTREDQEKVIS IFRDVFGQNSNPYRGTRQFLITPYNVQIGYSVLARGNYIPPPCRRLSLLHHSLQSLESIM KCVHMGWMVILVGPAAVGKTSLVELLAHLTGHRLKVMAMNSAMDTTELLGGFEQVDVIRP WQCLLEKVESAVRTLIRDSLLLTEICPDDAEVVLRAWSSFILNFKPKSLGEGSRSVTSEL VNKLEGILSLIQRLNNKINSYSKAEFSRLMEEFRHFRLQLVQSVDGKSHGTFEWVDGMLI QALQSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTMSERGVIDGTTPTVAPHPNFRLFL SMDPFHGEISRAMRNRGIEIYIPGESDGNLLDNLDMKVLLHGLGLQGDSVCNALMAVHSE AKETIAGSVLTLSSLIHATTLIVQQLHRGLGLVKSFYRACWEVYVRSQQSQMNQKLVLEL VMKHVSALTSHATWGDSLLAMGLWPDSLPAGLFLAEDSLLSTVQSDGQVLAYCLNRLSLK NSRTLPLTLQDLQKVMQSTNAESLRFSAVQMDAYWTDEIEVLSTSVELFIEKASNQDWML RVRWLNHLTKNLPQVLDSVRTQLEAGAASLNSFYSSPLSAGISSVIKLLQPNITDEHVMP LDPRWNMQFLNIIRNSMNFETEVEHTDQLFVLLMSVANRAILFLDREKRSYTEKNLITSK KLRTSALRMSLEFHKDPGSYNSLPHAIVANLAAFFELWDAFMLHWVKSSQVTLTDDNVHE IFYCLLWRDRFWAASDTLTVDSPGLALLSLHWHWVVKHLINRIPQMLAGHEQHKVSKEIQ SVSQQIHSCLANPAGISIGVKKLQKSLGRPLPFKDKLVMESVAQLKELSKALNILEMRPT FGESRWQDEICCLKTAATGWEIKKALLQATGLVLRANHLEDVNPGELRTFVNLQCSHLKA EGVKLGHSEEIHTEDTVSSQLDSASLIQLCSRIQLWPAMEYLAVLWQYKLTADCVTKACL SSLFFSYRENSNQQLHKCSELSQYVAFCLKLTPTASQHLYGLWHLLHLNKVSHEEMSLLW SELISSVLEFFWHSTVTTDPEYWLTWKPLPGAEERKMPKSPMYRFMKGPGVLNQAVFSKC LFEILTSSIKTSQWDASGLPVLSSSHVILGEWMERAQQLQEINTVLWTNMSVSSMAEFRC TDSRIQDVMLCRQLLALKDLIPVDLQEEYSQRCDKLSSKDPVAFQYILKVLKDVTGQEVL PKEVLCLLLTCLQQFFGEGEGIQDLSETARRGSLWVNMGLVQIQVWLPQTRFDPAVKREY KLKYAKEELHHLQCKWKTLNLSAQLHTGKDLEDEAITSFTHPHIRLLPQRMQQLKEQIDN LSRKQAFRPQVPPYDCLYQEVHQYVTSIAQISTVQDLLARLLQFLRGNRPKSLQAVQNLL NEEASWQESHHQFRKHLAEEYTLYPDAITPLQAAILQLQHGMRLVSSEVYATLNSMVCPA KLDTLVTSLLAFPSVGPTFPSYLSHADTLCSVQSMNILCGLKKLSLKRSEGESDERVQSS YPTQEQLLVNALLYLRCHVLSKGELDQKSLQLFRHLCQAIINEWDEQERCIQEQEEQESR LYRYRSKSYGTGRSEEEEEEREFRRRFPLYEKDFEDITAQASLEEKMENEDDSEDSVATE ITLLSQSSMQTVMMIHQQLCLNFARSLWYQQSLPPHQAKHYFSAFLSCYQTGASLVAHCY PLIGAEMNDYLLGSQLLVGTLLQNTLFEEVTSDLVIQQDAPYDFYQHPNIQQVRQCQPVL DNFTKEVNRLLQEWPEHPALMQLLVVMDRIRSFPLSSPLSKFLNGLEILLAKSQDWEENA SRTLSLRKHLDLVTQLIIQWRRLELNCWSVSLDNSMKQHTERSTKHWFSIHQMIEKYMQE QTEGSTEETNEQLSLTVLVHTLQAFIEGSTLGEFHTRLQALLVFHCHVLLMPQVEGKDML CSILWNLYNYYKQFAECVQARITELRQPIEKELKEFVKISKWNDVSFWAIKQSVEKTHRT LFKFMKKFESVLKEPCRPALVESDKEEGLDCLERQEESENKETKVQRLNSILRKTLSART DAAKTVLLEECYGGVMFDTESLQCRLPKLTKRMKMLCATLMKKNSFLDLVESLEQFTGDI IVSVVELQNLTINQAADKEKQKSEVKHILMQKQRALSDLFKSLTTTGLSYRKGLAWSRSK DPQDMLCLHPLDLHSALALVNCTHELDAKLLTEISSVWDGCQKYFYRSLARHSRLQTALL APAKEIGLGSIDRCKGFTAHLMKTLVKQRSSLTALTEQWIILRNLLSCIQEIDSRMNVTR EYNVAFPPQDSIQQWTERLQHLAMQCMMILEQLSWFVQCCPREQSLICSHDVRTDMKTNI PQCKGTEKNLENAQMGIPDLIQSELKYLSPVTAEQLPSGCRMRKQDQLWQQLSARVTEML TEIKTVKADIDRLRQQSCETLFYSWKDFEVCSSGLSCLLKVSAQLQSIESLYVLQGMEGR QSTKQMALIKSLEYIQGEVNKTAADFTTWKTQLLSLTSDCDGNQESDDGFVEHFSVQVET AIHVVLYAIQCLTERKQEEGKEEEKCSEEDEEEASADRLKSGLLTQLLDEDLYADVSSLH VQKIISAISELLERLKSYGEDCTADKHKFFNQSCYLLVRLMPMLSKYSDLILFYLIVSLA SHRSTGKLLSVLTSIFTELTQKGFCLPKELMEDAAGEGATEFHDYEGGGIGDGEGKKDVS DKIENEDQVEDTYQKGQEKEKEDPDSKPDIEGEDNAIEMSEDFEGKMHDGEQDKKEDSEK SDEDEELDKQMGNLGDAEADKLDERLWGDDNDDDDEEDNDNDDSKTEESGPGMDEGDSEL VAKDDNLDAGNKNDKKKPSKDEEKEEQAEDGENKEKIHEQIDEREYDENEADPYHGKQEK QLEAEALDLPDDLNLENEERSDEDKEGEEEENPFEIEEKPVDLDEAENGEDKDGEDTQDT GRDPEPAEGSTSEDKAEGEGEVGEEADDQEEGNTENSEENEEEKTQPLTEDKESAEEERE KGIPAADQGLQPQEEEDEDSLEKDEQLPESVERMEHEAHGSTGEENLQSDSAVELAGAAS EKDQAKEEHGSGAADANQTEGHESNLMARLASQKQSRKNTQSFKRKPGQADNERSMGDHS EHVHKRLRTIESSSEAKQNTTQPEQNVEEADAFEHIKQGTESYDAQTYDVASKEQQKPTM PLGEEKEEVVSEEAAMETEMQNNEDLNAVDTEELKPEVKKYSATKTLGSDEMELEIQAFN SEEVKDANADKQPKVPEEEPERNQDSTIHMAHQFLMDTTVLHIIKDPEELRQELEKQLEA WQTQQSGNPDEEKTAAEMWQRYLALTAPLSQQLCEQLRLILEPTQAAKLKGDYRTGKRLN MRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMIDNHSKQLAYESLAVIGNA LTLLEVGQIAVCSFGETVQLLHPFHEPFSDQSGTRILRLCKFQQKKTKIAQFLESSANMF AAAQQLSQNINPETAQLLLIVSDGRGLFLEGKERVTAAVQAAQNANIFVIFVVLDNPNSR DSILDIKVPIFKDPGEMPEIRSYMEEFPFPFYIILRDVNALPETLSDALRQWFELVTASE SL NT seq 16749 nt NT seq  +upstreamnt  +downstreamnt atggaggccctgcggctccacctagccggtgcgctgcagctggtggcgcagcggaacgag aagagcagcagcgagctgggcaggttcctggccaagcagatctggactcggcaggatcgc cagtgtattctcaatgccttagcacagttattagtggataaagaatgtactctactgatt ggtcgtcagtttcgaccaatcctgctggatttactggaaagaaatgcagaagccattaat gctggtggccaaatcaaccacgatctgcatgaaaggctttgtgtagcaatgagcaagctc attggtgaccaccctgatgtgcttccgtttgctctcagatattttaaggatacatcacca gtgttccaaagactcttcttggaaagttctgatgcaaacacagtccgatatgggcgcaga cggatgaagttacgtgatctcatggaagctgcatacctattcctccaacaagagcagtct gtattccgggaattgtgggactggagtgtgtgtgttccgctgctaaggagtcatgatact ttggtccgctggtacacttcaaattgccttgctttggttacatgtatgaatgatgagcac aaattatctttccttaagaagatcttcaatccagatgaattaatacgtttcagactaaag caactggaagaatcacagatgtggaatgtggagagagcccttgttttggccaatccagac acctctctttggcacagagagaaagggctgcagtacacacaaggagacatcatatcaggt gacctctctgcaaatgtaatagcagtatgtggagttgtgctaccaaggcaacaacttgtg cctaaagaacaggaaagtaccattcagaattttgtgctggttgaatctacctgcatgaat cttcaaaaccttgcaatggcagtagctttccagaatcctgtattattagagggaccaata ggatgtggcaaaacttctttaattgagtatttagcagtcattacaggaagaatgaagccc cctcatattctgaaagttcaacttggagatcagacggacagtaagacattactgggtatg tatcgttgtacagatgtgccaggggagtttgtgtggcagcctggaactttgacacaagct gtcaccaaagggcactggattctgctggaggatattgactatgctcctctggatgtgatc tcagtgctgattcctcttctggaaaatgaagaattactgattcctggtcgtggagactgt ttaaaagtgtctcctggattccagttctttgcaaccagaagagtcttcagctgtggtggt ggttggtaccgacaacaaaacagtcatgctactcttctggacaagcattggaccaaaatt cggatggataacatgaataaagcagaactcaaagagattcttcagggcagataccccaac cttgctgctgtgactgatcgtctactagacatttatattcagctgactggagacaagcat cagacaacagaaatcagttttcctgcctgtgagcagggagtggaagatacatcagaaatg agaaaagaaaacaaaaggccaaatctggagggaagagaactctctctgagagatttattg aattggtgcggcaggattgcctacaactttgacagctcttcctcaactactgcagtgaat atttttcaggaggcattagactgtttcacagctatgctgtccaagcaagggagcaggcag aaaatggcagaaattattggaagcaaactaaacatttccaagaaaaaggcagagttctat tgtcagcttcataaaccagaaattctaacaagggaacatgaagtcgctgtgggaagagtg cggctcttgcggaagcaaactcaggcacttcttatacaaagggagaagcaaaactttgct gccacacgcccatcttcggtactgattgaacagcttgcgatgtgtgttgacaaaggagag cctgtgctattggtgggtgaaacaggaactggcaaaacctcgactgtccaataccttgct catattacaggacaccatttgagggttatcaatatgaaccaacagagtgacactgcagat ctgcttgggggctataagccagtggataacaaattgatttggctgcccttacgagagtct tttgaggaactcttctctcagacgttttccaggaagcaaaatcaaactttcttgggtcat atccagacgtgttacagacagaaacgttggcatgatctactcaaattaatgcagcatgtt cacaaatcagccattaataaggaagcaaaagaaaacacatcaggctcaccactgaaagaa aagtgggaagcatttggtcttagacttaaccatgcccatcaacagatgaaaatgacagaa aattttctggtgtttgcatttgtagagggtactctggcacaagcggtgaagaaaggagag tggattttactggatgagattaatttggcttcagcagagactttagaatgcctgagtggc ttgctagaaggatcatctggctcactggtgttactagacagaggagacacagaacctctg gtgcgtcaccctggttttcgtttgtttgcctgtatgaatccagctacggatgttggaaag agaaatctacccccaggaataagaaacaggtttactgaactttatgtagaagaactgcag aatgaaggagacttgctaattcttatcatggactatctgaaaggcttgaatgtgagcaaa aacacagtacaaggaatcatgaacttctatttatctgtgagaaaagagacagaagcaaaa ttggtggatgggactggccatagacctcactacagccttcgaacactttgcagggctttg agatttgcagcatctaatccatgtaaaaacatacagcgctcactgtatgagggcttttgc ttgggcttcctgacacagcttgacagagtttctcacccgatagttcagaagctaatttgc cagcatattgtctctggcaacatcaaaagcctccttaagcagccactaccagagccccaa ggagggagagctgtacaaatagaaggttactggatttcagtgggggataaggaacctgtg atagatgagacttatgtactaacttcttctgttaaacttaatctgaaagacattgtcaga gttgtgtctgcagggactcatccagtgctgattcaaggagagacatcagttggtaaaact agtttaattcgctggttggctgcagctagtgggaaccgctgtgtgcggattaacaatcac gaacatactgacatccaggagtatattggctgttatacgtcagacgcttctgggaagctg atgtttaaggaaggtgtccttattgatgctatgagaaagggctactggattatcctcgat gaactgaatttggctcctacagatgttctggaggcactcaacagactgctggatgataac agagagctgttcataacagagacacaagaagttgtcagggcacaccctcgatttatgctg tttgctacacagaatccaccaggactgtatgggggcaggaaggtgttgtccagagccttc aggaatcgttttgtggagctgcattttgatgagctgccaagtgctgagctagaaacaatc cttcacaagcgatgcagtctgccaccttcttactgcagtaaactcgtcaaaatcatgctg aatctgcagtcttatcgcagaggttcaacagtgtttgctgggaagcatggtttcattact cttcgagatctgtttcgttgggctgaaagatacagattggcagaacagacagagaaggat tatgactggcttcagcatttagcaaacgatggtttcatgcttctggcaggcagagtcagg aagcaggaggaggttgatgttattcaaagtgtccttgaaaagcattttaagaagaaattg tatcctcactctctcttctcagaggaaagtgttagaaagttattggttaaatcatctacg cagatgtcggtgatggacagcgagtttagtcatgttgtctggactcaagggatgaggagg cttgcagttctggtaggacgagccctggagtttggcgaaccagtactgctggtgggagac actgggtgtggcaaaactactatttgtcagatatttgcagccttggcaaatcagaaatta cattctgtgaactgccacttgcatatggagacatcagacttcctgggaggactacggcca gtcagacagagatcaaaggacaaggaggaatttgacagttctagactctttgaatggcac gatggaccccttgttttagcaatgaaggaggacggcttttttctcctggatgagatttca ttagctgatgattctgtgttggaaagacttaatagtgttcttgaagttgagaagacgctg gtgcttgctgaaaaaggtagtcaagaagatgaggataatgaagtagaacttctgattgcg ggaaagaaatttcgcatcctagcaaccatgaacccaggaggtgactttggaaaaaaagag ctttctcctgcactgcgcaacagatttacagagatatggtgtccacagagtaacagtcgt gaggatttaatacagatcgtaaagcacaatcttcatccaggactgtctctggacaggata aaccaccaagggacagacatagctgagctgatgatggactttattgaatggctaaccaac caagaatttgggcgtcagtgtattctcagtgtccgggacgtcttatcgtgggttaacttt atgaatgtcatggtagaagatgaggagtacagcctattttacatctctactgtgacgtct tttgtccatgctgcgtgcctggtgtacattgatggaataggttcaggtacaacatcttgt tctgctgatactgctttatccgctcgtgaaaaatgtctgaaattcttatgtgagaaactt tgcactattgttgagcttacggaatatcagaaggatgaactgaggatttactacagaaca aaggagagagaatttatatggatggaaaacttcatcggagtccatccattttttatacca agaggccctgtttttcagaggaacagtgtttcagattatgctttaaatgcaggaactaca gcagtgaatgcacaaaggctgttaagagccttacagcttaacaaacccattctgctggag gggtctccaggcgtgggcaagaccagtctagtagcagcattggcaaaggcttcaggaaat tgccttgttcgaatcaacctgtctgagcaaacggatgtgacagatttatttgggacagac ttgcctgtggaaggtggaaagggaggagaatttgcctggcgtgatggacccctgcttgca gcattaaagggtggacactggattgtattagatgagttgaatctggcttctcagtctgta ttagaaggactaaatgcctgctttgatcaccgagcagagatttacatcccagaattaggg atgagttttcatgtgcaacataagaagacgaagatctttggatgccagaatccctacaga caaggaggtggaagaaaggggctgcccaagtcctttcttaatagatttacacaggtatat gttgatccacttacagctgcagatatggagttcattgggaataccctgtttcctgccatc gacaaaaatattattgctaaaatggttgctttcaataacaagattgatcaagaggttaat gctctcaagaagtggggacagaaaggaggaccctgggaatttaacctgcgtgatcttttt cgctggtgtcagctgatacttgttgatcagtcaccaggatgctatgatccaggccaacat gtatttttggtctatggtgaaagaatgagaaccagagaagaccaagagaaggtcatttcc atattcagggatgtttttggccagaattctaatccatataggggaaccagacagtttctc atcactccttataatgttcagattggctactcagttcttgctcgtggcaactatattcct cccccttgcagacgtctgtctcttttacatcattccctgcagtcccttgagtccataatg aaatgtgtgcatatgggctggatggtaatattggtgggtcctgcagctgttgggaagacc agccttgttgaacttctggctcacctgacaggtcatcgattaaaggttatggcaatgaac agtgctatggatacaactgaactcttaggtggatttgaacaggttgatgtcattcggcca tggcagtgcctactagagaaagtggagagtgctgtgaggacactaataagggacagtctc cttctgactgaaatctgtcccgatgatgctgaagttgtgttgcgtgcttggagcagtttc atccttaactttaaacccaaatctctgggtgaagggagtagaagtgtcacaagtgaactg gtgaacaaactagagggaatactttcacttatccagcgactaaacaacaaaataaactct tattcaaaagcagagttttcgagactgatggaagaatttagacatttcaggctgcagctt gttcagtctgtggatggtaaaagtcatggcacttttgaatgggttgatggaatgttgatt caggcgttgcaatctggggactggcttttaatggacaatgtaaacttctgcaatccatca gtgctggaccgcttgaatgctctactcgaacctgggggcgtccttaccatgagtgagaga ggtgtgatagatggcaccacccctactgttgcccctcatccgaatttcaggcttttcctt tcaatggatccttttcatggggaaatatccagagccatgaggaaccgtgggattgagatt tacattcctggggaaagtgatgggaatttattggacaatctggacatgaaggtgttgctg catggactgggcttacaaggagacagtgtatgcaatgcactcatggctgtacattcagaa gctaaagaaactatagcaggttctgtgttgacattgtcatctttgattcatgctactaca ctaattgtacaacagttgcatcgaggccttggtttagtgaagagtttttacagagcttgc tgggaagtgtacgtccgctcacagcagtcccagatgaaccaaaagcttgtgctggagttg gtaatgaagcatgtttcagctctgacttcccatgcaacttggggtgactccctgctagca atgggattgtggccagactctctacctgcaggtctgtttttagctgaagactcacttctt tctacagtccagagtgacggacaggtccttgcatattgtctgaacagactgagcctgaaa aacagcagaacactgccacttactctgcaagatttgcagaaagttatgcaatccactaat gcagagagtctccgattcagtgctgttcagatggatgcctattggacagatgaaattgaa gtcctatctacttctgttgaattgttcatagaaaaggcatccaatcaggattggatgttg agagttagatggcttaatcacttaaccaagaatctaccacaagtgcttgattcagtgcgc actcaactagaagctggtgccgcatcgctgaacagtttctactccagtcccctctctgct ggaatcagtagtgtgatcaagttgctacagccaaacataacagatgaacacgtgatgccg ctggatccaagatggaatatgcagtttttgaatatcattagaaattcaatgaactttgaa acagaagtggaacacacagatcagctttttgtccttctgatgtctgtagcaaaccgggca atattatttcttgaccgggaaaaaaggagctatactgagaagaacttgattactagcaaa aagttgagaactagtgccttaagaatgtctctagagttccataaagatccagggagttat aactctcttccacatgctattgtggccaatcttgctgctttctttgaactttgggatgcc tttatgttgcactgggtgaagtcttctcaagtgaccttaacagatgacaatgtgcatgag atcttctactgcttgctgtggcgtgaccggttttgggcagcatctgacacactgacggtg gattctccaggcttggcactcctatcgcttcactggcactgggttgtgaagcatttaatt aacagaattcctcagatgctggctggacacgagcagcacaaggtttccaaggaaattcag tctgtttcacagcagattcatagctgtttggccaatcctgctggtatttctattggtgta aagaagctgcagaagtctcttgggagacctcttcctttcaaggataaactggtgatggag tctgttgctcagttgaaagaactcagcaaagcactcaacatcctggagatgagacctacc tttggagaaagcagatggcaggacgaaatctgttgtctgaaaactgctgccactggatgg gaaataaagaaagcactgctgcaggccacgggtctggttctcagagctaatcatttagaa gatgttaatccaggtgaattaaggacgttcgtgaatttacagtgttcacacctgaaagca gaaggagttaagcttggtcattcagaagagattcatactgaagacacggtctccagtcag ttggattctgcctcattaatccagctctgtagtaggattcagttgtggcccgcaatggag tatttggcagtgctctggcagtacaaactgacagcagattgtgtaactaaggcttgccta agcagccttttcttcagctacagggagaacagcaatcaacagctacacaagtgttcagag ctaagtcagtatgtggctttttgccttaaactgacgccaactgcctctcaacatctgtat ggactgtggcacttgttacatcttaataaggtatcccatgaagaaatgtctcttctgtgg tcagaactgatcagtagcgtattagaattcttctggcacagtactgtaaccacagatccg gagtactggttaacctggaagccgctacctggtgcagaggaaaggaaaatgcctaaatcc cctatgtaccgttttatgaagggcccaggtgttttgaaccaagcagttttctcaaagtgc ctctttgaaattctaactagcagcatcaagacaagccagtgggatgcgagtggccttcct gttctgtcctcatcccatgtgatactgggagagtggatggagagagcacaacagcttcaa gaaatcaacacagttttgtggaccaacatgtctgtttcttccatggcagaatttaggtgt acggattccagaatccaggatgtaatgttatgtcggcagctcttggctctgaaggatctg attccagtagacctgcaagaggaatattcacagcgctgtgataaactctcctccaaggac cctgtggcttttcagtacattctcaaagtacttaaggatgtcactggtcaggaggtactg ccaaaagaagtcctctgtctcttgctgacctgcttgcagcaattctttggggaaggagaa ggaattcaggacctatcagagacagctcggcgaggtagcctctgggtgaatatgggtttg gtgcagatccaggtgtggcttccacagactagatttgatcctgcagtgaaaagagaatac aaactcaagtacgccaaggaggagttacaccacctgcagtgtaaatggaagacactgaat ctgtcagcacagttacatacaggaaaagatcttgaagatgaagcaattaccagtttcacg catccgcatatcagacttctaccccaaagaatgcaacagctgaaggaacaaatagacaat ctttccagaaaacaggccttcagaccccaagtcccgccatatgactgcttataccaggag gttcaccagtatgtcaccagcattgcacaaatttccacagtccaggatctcttagcccgt cttctacagttccttcgtggaaatagacctaagtcgctccaggcagtacagaacctgcta aacgaagaagcatcctggcaggaatctcaccatcaatttagaaaacacttggcagaagaa tatactttgtaccctgatgctatcaccccactgcaagctgccattttacagctgcagcat ggcatgagactagtgtcctctgaagtttatgcaacactcaatagtatggtctgtccagcc aaacttgacacccttgttacctctttgttggcatttccttctgttggtcccaccttcccc agttacctttcacatgcggatactttatgctcagtgcaatctatgaacatcctctgtggc cttaaaaagttatctctgaaacgctctgaaggagagtctgatgaaagggttcagagttca tacccaactcaggaacagctgctagtgaatgccttattgtatcttcgatgccatgtattg tctaagggagagctggaccagaaatctctgcagcttttcaggcatctgtgtcaggcaatt ataaacgaatgggatgaacaggagcgctgcatccaggagcaggaggagcaagaaagtcgt ctgtacagatacaggagtaagagctatggaacggggcgaagtgaggaagaggaggaagag agagaatttaggaggagattccctctctatgagaaggactttgaagatatcacagctcag gcaagtctagaagaaaaaatggaaaatgaagatgattccgaggattcagtagccactgaa ataactctcttatcccagagttcaatgcaaacagtgatgatgattcatcagcagttgtgc ctaaacttcgcacgatccctgtggtatcaacagagcctgcccccacatcaagctaaacat tatttcagtgcgtttctttcctgctatcagactggtgcttctctagtggcacactgctat cccttgatcggtgctgaaatgaatgattatcttcttggcagccagcttttagttggcaca cttctccaaaatacactttttgaggaagtgacttcagatctcgtcatacaacaagatgcc ccgtatgacttttaccagcaccctaatattcagcaagttcgacaatgccagcctgtactt gataacttcactaaagaagtaaacaggttactgcaagaatggcctgaacaccctgcactt atgcagctattggttgtgatggacagaatccgtagcttcccactctccagtcctctctca aagttcctgaatggcttagagattctgcttgcaaagtcacaggactgggaggagaatgca agtcgaactttatctttgcggaaacatcttgatttggtcactcagttgatcatccagtgg cgtagactggagttaaactgctggtcggttagtctggacaatagtatgaagcagcacaca gaaagatccacaaagcactggttctcaatccatcagatgatcgagaagtacatgcaagaa caaactgaggggagcacagaagaaaccaatgagcagctgagcttaacagtgctggtccac acactgcaagcttttattgaaggatctaccttgggggaatttcatacacgacttcaagca ctgttggttttccactgtcatgtcctgctaatgcctcaagtagaaggaaaggacatgctg tgcagcattctgtggaacctatacaattattacaagcagtttgcagaatgtgtacaagcc aggattactgaacttcgtcagcctatagaaaaagaacttaaggaatttgtgaaaatttct aagtggaatgatgtcagcttctgggctataaaacagtctgtggagaagacacacaggacc ctctttaaattcatgaagaagtttgaatctgttctgaaggagccctgtcgacctgccctg gttgagagtgataaagaggaagggctagactgcttggagaggcaggaagagtctgagaac aaagagacaaaagttcagaggttaaacagcatattaagaaaaactttgtctgctagaaca gatgctgccaagaccgtgctcttagaagaatgctatggtggagttatgtttgatacagaa tctcttcagtgtcgtttgcccaagcttacaaagcgaatgaagatgttatgtgcaacgctt atgaagaagaactcatttctagacctggtggagagtcttgagcagtttacaggtgatatc attgtctctgtggttgaactgcagaacttaacaattaatcaggctgcagataaggaaaag cagaagtcagaggtcaaacatattcttatgcagaaacaacgggccttatcagatctcttt aaaagccttactacaacaggtttgtcatatcgaaagggccttgcttggtctcgttcaaaa gaccctcaggatatgctttgcctgcaccccttggatttacacagtgcactagccctagtc aactgcacacatgaattggatgccaagttgctgacagagatctcttctgtctgggatgga tgccagaagtacttctatcgatctcttgcacgccactctaggcttcagacagcattatta gcacctgccaaggaaattggactaggtagcattgatagatgtaaaggattcactgcacac cttatgaagacacttgttaagcagaggagctcactcactgccttgacagaacagtggatt atactgaggaatctcctgagttgtatacaggaaattgattcaaggatgaatgttactaga gaatataatgtagcctttcctcctcaagatagtattcagcagtggactgagagactgcaa catcttgccatgcaatgtatgatgatccttgagcagctgtcttggtttgtacagtgctgc ccaagagaacagtctttaatctgtagtcatgatgtaaggacggatatgaaaacaaacatt cctcagtgtaaaggaactgaaaagaatctggaaaatgcccagatgggaatacctgatcta atccaatcagagctaaaatacctatctccagtgactgcagaacaactgccctccggatgc aggatgcgaaaacaggatcagctgtggcagcaattgtctgcaagagtgactgagatgctc acagagattaagaccgtgaaagcagatatagacagactaagacaacagtcttgtgagacc ttattttattcctggaaagattttgaagtttgcagttcagggctgagctgtttgttgaaa gtctcagctcagttgcagagcatagagtccttatatgttcttcaagggatggaaggtagg cagtccacaaagcagatggcattaatcaagagcctagaatacatccaaggggaagttaat aaaactgccgcagacttcactacctggaaaacccagcttctcagtttgacgtcagactgt gatgggaaccaagaatcagatgatgggtttgtagaacatttctcagtgcaagtagaaact gccatccatgttgtcctgtatgctatccagtgtttaacggagagaaaacaggaagaagga aaggaggaagaaaaatgctcggaggaagatgaggaggaggcctcagccgacagactcaag tcagggcttttaactcagctcttggatgaagacctctatgctgatgtgagttctctgcat gtgcagaaaataatttcagccatttcagaactcctggaaagactgaaatcttatggagag gattgcacagcagacaaacacaagttcttcaatcaatcctgctacttacttgtgcgccta atgcccatgctttccaagtattcagatcttatcctgttctatctcattgtttccttggca tctcacagaagtactgggaaattgctttctgttctaactagtatatttacagagctcacc caaaagggattttgtctgccaaaagaattaatggaggatgcagctggagagggagcaaca gagttccacgattatgagggaggtggtattggagatggggaaggcaagaaggatgtgagt gacaaaatagaaaacgaagaccaggtggaagacacttatcaaaaaggtcaagaaaaggag aaagaggatccagactccaaaccagacattgaaggagaggacaatgcaattgaaatgtca gaggactttgaagggaaaatgcatgatggggaacaggacaaaaaagaagacagtgagaaa tcagatgaagatgaagagctggataaacagatgggaaatcttggtgacgctgaagctgat aaactggatgagaggctctggggtgatgacaatgacgatgatgatgaagaggacaatgac aatgatgacagtaaaacagaagaatccggaccaggaatggatgagggtgattctgagctt gttgcaaaagatgacaacttggatgcaggcaataaaaatgataaaaagaagccatccaag gatgaagaaaaagaggaacaagcagaggatggtgaaaacaaagagaaaattcacgaacaa atagatgagcgtgaatatgatgagaatgaggcagatccctatcatggtaagcaagagaag cagcttgaagctgaagctttggaccttcctgatgacctgaacttagagaatgaagagagg agtgatgaggacaaggaaggagaagaagaagaaaatccttttgagatagaagagaagcca gtggatttagatgaggctgaaaatggagaagataaggatggagaagatactcaagataca ggcagagatccagagccagctgaaggaagcacctctgaagataaagcagagggtgaaggt gaagtgggggaagaagctgatgaccaagaagaaggaaatacagaaaactctgaggaaaat gaagaggagaaaacacaaccactgacagaagataaagaatctgctgaagaggagagagag aaagggatcccagctgctgaccaaggccttcaacctcaggaagaagaggatgaagatagt ctggagaaggatgagcagttacctgaatctgtagagagaatggaacatgaagctcatggg tcgacaggagaagaaaatctgcagagtgacagtgctgttgagctggctggagcagcttca gaaaaggaccaggctaaagaggaacatgggagtggagctgcagatgcaaatcaaacagaa ggccatgaatccaacttaatggcacgactggcttctcagaaacaaagcagaaaaaataca cagagttttaagaggaaacctggtcaggctgacaatgagcgctcaatgggggaccacagt gaacatgtccacaagcgactgagaaccatagaatccagcagtgaagccaaacagaataca actcagcctgaacaaaatgtggaagaagctgatgcgtttgaacacattaaacaaggcact gaatcctacgatgcacaaacttatgatgtagctagcaaggagcagcagaaacctactatg cctcttggtgaagagaaggaagaggtggtttctgaagaagcagccatggagacagaaatg cagaacaatgaagacctcaatgctgtagacacagaggagctgaagccagaagtaaagaag tatagtgccactaaaacccttgggtctgatgaaatggagttggaaatccaggctttcaac tccgaggaggtcaaagatgctaacgcagacaaacaaccaaaggtgccagaggaggaacca gaaagaaaccaagactctactatacatatggcccatcaatttttgatggacactacagtc ctgcatataattaaagatcctgaagagttgagacaggaactggaaaagcaactggaagct tggcaaactcagcaatctggaaacccagatgaggaaaagacggcagctgagatgtggcag aggtatttagcactgaccgctcctctttcacaacagctttgtgagcagctacgactcata cttgaacccactcaggcagctaagttgaaaggtgattacagaacaggaaaaagactgaat atgcgcaaagtgattccatatattgccagtcagttccgaaaggataaaatctggttgcga agaaccaagcccagcaaacgtcagtaccagatttgcttggccattgatgactcgtctagt atgatagacaaccactccaaacagcttgcatatgaatccctggcagtgattggaaatgca ttgacccttctggaagtggggcagattgctgtatgtagctttggagagacagttcaactt ctgcacccattccatgaaccattcagtgaccagtcaggaacacggatattacgcctctgc aaatttcaacaaaagaaaactaagatagctcagtttctagaatcatcagcaaatatgttt gctgcagcacagcagttgtctcaaaatatcaatccagaaaccgctcagctgctcttgata gtatctgatggaagaggccttttcctagaaggcaaggaacgagtcacagcagcagttcag gctgctcaaaatgccaatatctttgtcatttttgtcgtattagataatcctaattcccgg gattccatcttggacattaaagtacctatattcaaagaccccggagaaatgcctgaaatc agatcctacatggaagagttcccattcccattctacataatcctcagagatgtgaatgcc ctcccagagactctcagtgatgcactgcgacagtggtttgaactggtgactgcctcggag agtctatag

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