Caretta caretta (Loggerhead turtle): 125638619 Help Entry 125638619         CDS       T09292                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism ccay  Caretta caretta (Loggerhead turtle) Pathway ccay04020   Calcium signaling pathway ccay04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:ccay00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     125638619 (RYR3)    04020 Calcium signaling pathway     125638619 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:ccay04040]     125638619 (RYR3) Ion channels [BR:ccay04040]  Voltage-gated cation channels   Ryanodine receptor    125638619 (RYR3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY MIR Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_5 Motif Other DBs NCBI-GeneID:  125638619 NCBI-ProteinID:  XP_048710595 LinkDB All DBs Position 6:complement(68655267..69230566) Genome browser AA seq 4903 aa AA seqDB search MLIPIGEEELYRAQQAASGGNQSLSRADSSRAMAEGGEGGEDEIQFLRTDDEVVLQCVAN IQKEQRKFCLAAEGLGNRLCFLEPTSEAKYVPPDLCICNFVLEQSLSVRALQEMLASTGE NASEGAVQGGGHRTLLYGHAILLRHSFSGMYLTCLSTSRSQTDKLAFDVGLQENAAGEAC WWTIHPASKQRSEGEKVRIGDDLILVSVSSERYLHLSMSNGNVQVDASFMQTLWNVHPTC SGSSTEEGFLLGGHVVRFFHGHDECLTIPSTDQSDSQQKRVLYEIGGAGVRARSLWRVEP LRISWSGSYIKWGQPFRLRHITTGQYLALTEEQGLSLLDRGKSDTKSTSFCFRASKEKLE TVHKRDIEGMGVAEIKYGDSICFVQHVTSALWLTYQAQDAKAPRLGPLKRKVILHQEGHM DDGLTLQRCQHEESQAARIIRNTSSLFSQFISGNNRTAAPIALPIEEVLETLQDLITYFQ PPEEELEHEDKQNKLRSLKNRQNLFKEEGMLALVLNCIDRLNVYNSAAHFAGVAREESGT AWKEILNLLYKLLAALIRGNRNNCTQFSNNLDWLISKLDRLESSSGILEVLHCILIESPE ALNLIAEEHIKSIISLLDKHGRNHKVLDVLCSLCLCNGVAVRANQNCICDNLLPRRDLLL QTRLINDVTSMRPNIFLGVAEGSAQYKKWYFELIIDQVDAFLTAEPTHLRVGWASTSGYA PYPGGGEGWGGNGVGDDLYSYGFDGLHLWSGRVPRAVASVNQHLLASDDVVSCCLDLGVP SISFRINGQPVQGMFENFSVDGLFYPVVSFSAGIKVRFLLGGRHGEFKFLPPTGYAPCYE ALLPKEKMKLEPVKEYKRDSDGVRDLLGTTQFLSQASFIPCPIDTTQIVLPLHLEKIRDK LAENIHELWGMNKIELGWTYGKIRDDNKRQHPCLVEFSKLPETEKNYNLQMSTETLKTLL ALGCHIVHANLAAEEDLKKVKLPKNYMMSNGYKPAPLDLSEVKLLPSQEVLVDKLAENAH NVWAKDRIKQGWTYGIQQDLKNKRNPRLVPYALLDERTKKSNRDSLREAVRTFAGYGYNI EPPDQELADQTVAKVSIDKIRFFRVEQSYAVTSGKWYFEFEAVTGGDMRVGWARPGCRPD IELGADDQAFVFEGSRGQRWHLGSGFFGRNWQPGDVVGCMINLDDKSMIFTLNGELLITN KGSELAFADFEIEKGLVPICSLGLSQIGRMNLGMNASTFKYYTMCGLQEGFEPFAVNMNR DVAMWFSKRLPTFVNVPKNHAHIEITRIDGTIDSPPCLKVTHKTFGTQNSNADMIYCRLS MPIEFHSSFNYGTGVTSASADAFQKRKQNQETALHTTTYYYSVRIFAGQDPSSVWVGWVT PDYHFYSENFDLNKNSTVTVTLGDERGRVHESVKRSNCYMVWGGDISANSQRSSRSNVDL EIGCLVDLGTGMLSFTANGKDLGTCYQVEPTTKLFPAVFIQPMSTNLFHFELGKLKNTMP LSAAIFKSEEKNPIPQCPPRLDVQTITPVLWSRMPNSFLKVETERISERHGWVVQCLEPL QMMALHIPEENRCVDILELCEQEDLLQFHYHTLKLYSSVCALGNNRVAYALCSHVDLSQL FYTIDNQYLPGLLRAGFYDLLISIHLERAKEAKLMMNNEFIIPITDETRKIELYPDESKR HGLPGVGLSTCLKPGFNFSTPCFIVASEEHQKPSPEIPLEILKTKAISMLTEAVHCSGVH IRDPVGGKVEFQFVPVLKLIGTLLVMGVFDDDDVKQILLLIDPNVFGEHKEETEEKTDKE EVTQIEEKAVEAGEEALKETKPPMKGLVQTRLPESVKLQMCELLNYFCDCELRHRVEAIV SFADNYVSKLQYNQKYRYNELMQALNMSAALTAKKTKEFRSPPQEQINMLLNFQLREDCP CPEEIREELYEFHDDLLIHCGIPLEEEEEMDEDTSWMGKLRSLIYKIKGPPKAEKKEPTE VEEKSPTTLKELISQTMVRWAQEDQIQDPELVRIMFNLLRRQYDSIGELLQALRKAYTIS AASVQDTINLLAALGQIRSLLSVRMGKEEELLMINGLGDIMNNKVFYQHPNLMRILGMHE TVMEVMVNVLGGDKSQQIAFPKMVASCCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGL ASPSMRGSTPLDVAAASVMDNNELALALEEPDLEKVVTYLAGCGLQSCPMLVAKGYPDIG WNPIEGERYLSFLRFAVFVNSESVEENASVVVKLLIRRPECFGPALRGEGGNGLLAAMQG AIKISENPTLDLPSQCYKREVSVEEEEEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQ TGKGEAIRIRSILRSLVPTEDLVGIISIPLKLSTVNKDGTVNEPDMSASFCPDHKAPMVL FLDRVYGIKDQSFLLHLLEVGFLQDLRASASLDTVSLSTTEAALALNRYICSSVLPLLTR CAPLFSGTEHYASLIDSTLHTIYRLSKGRSLTKAQRDTIEECLLAICHHLRPSMLQQLLR RLVFDVPLLNEYCKMPLKLLTNHYEQLWKYYCLPSGLGSYGIAAEEELHLTEKLFWGIFD SLSHKFLSLLQKYDPELFRMALPCLSAIAGALPPDYLDTRIRVTLKKQTSVDPEGNFDPK PINTINLTLPEKLEYIVSKYAEHSHDKWACDKSNSGWKYGVSLDENMKTHPLIRPFKTLT EKEKEIYRWPARESLKTMLAMGWSLERTKEGEAMVQQRENEKLRSISQPSQGNGYSPTPL DLSNVVLSRELQGMVEVVAENYHNIWARKKKMELESKGGGSHPLLVPYDTLTAKEKSRDR EKAQELFKFLQMNGIVVSRGLKDMDLDASSMEKRFAFKFLKKILKYVDSAQEFIAHLEAI VTSGKTEKSPHDQEIKFFAKVLLPLVDQYFTNHCLYFLSSPIKSLSSSGYASNKEKEMLA SLFCKLAALVRHRISLFGSDATTMVSCLHILAQTLDTRTVMKSGSELVKAGLRAFFENAA EDLEKTLENLKLGKFTHSRTQIKGVSQNINYTTVALLPILTSIFEHIAQHQFGVDLLLGD VQVSCYRILCSLYSLGTGKNIYVERQRPALGECLASLAAAIPVAFLEPSLNSYNPLSVFN TKTARERAILGMPDTVEEMCPDIPQLDGLMKEINDLAESGARYTEMPHVIEVTLPMLCNY LSYWWERGSENMPKSAGPCCTMVTSEQLSIILGNILKIINNNLGIDEASWMKRIAVYAQP IISKARPDLLKTHFIPTLEKLKKKAIKIVMEEEQLRADSKSDTQEAELLILDEFAVLCRD LYAFYPMLIRYVDNNRANWLKKPDADSDELFQMVAEVFILWCKSHNFKREEQNFVIQNEI NNLAFLTGDSKSKMSKSGGQDQERKKLKRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGD QELISLAKIRYSHRDTDEEVKEHLRNNLHLQEKSDDPAVKWQLNLYKDILKSEEPADPEK AVERVQRISAAVYHLEQVEQPLRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHKIST FFLSTFQRVWLEKVHEKTQYDRLILMLTTPPKKDEEEVEETEKHPDPLHQIILHFSRNAL TERSKLDDDPLYTAYSAMMAKSCQSEEEEEEDEEKEKTFEEKEMEKQKTLYQQARLHDRG AAEMVLQMISASKGELGPMVIETLKLGIAILNAGNTLVQQKMLDYLKEKKDAGFFQSLSG LMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVLQNDEFTRDLFRFLQLLCEG HNNDFQNFLRTQMGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKNVIDESGQRNFSKA LAVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSKDSSQIELLK ELLDLLKDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTSS DAFKDYDPDGKGIISKKEFQKAMEGQKQYTQSELEFLLSCAEADENDMFNYVDFVDRFHE PAKDIGFNVAVLLTNLSEHMPNDSRLQCLLDPAASVLNYFEPYLGRIEIMGGAKKIERVY FEISESSRMQWEKPQVKESKRQFIFDVVNEGGEQEKMELFVNFCEDTIFEMQLASQISES DSAERPEEEEEDEPYYVMEVGDDEEEEKSLESASAFAMACVAVKRNAANFLKMVTLRNLR KQYRKVRKMTIKELVKVFFSFFWMLFVGLFQLFFTIVWGIFQILWSTVFGGGLVEGAKNI KVTKILGDMPDPTQFGIHDDIMEAEKVEGIEHGIRVELVQFVKGEKGETDIMSDIFGIHA KKEGGSKHGHDAGLGDVAEIVGTDTPPSLESTVRRKRKAQISEIAKEDETETKAESEKAD MEDGEKEDKAKEEVQSEHLGKEETKKKKRRHGQKIEKPEAVMANFFKVVEIYQTKMLHYL ARNFYNLRFLALFVAFAINFILLFYKVTEEPLDELEEDSDLWNSFEEEEEEEGVVFFVLQ ESTGYMAPTLRALAVIHTIISFVCVIGYYCLKVPLVVFKREKEIARKLEFDGLYITEQPS EDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKNALDFSPV EETEPEEASLVSWLSSIDTKYHIWKLGVVFTDNSFLYLAWYTTMSILGHYNNFFFAAHLL DIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDM KCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRIVFDITFFFFVIVILLAIIQG LIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHGFEMHTLQEHNLANYLFFLMY LINKDETEHTGQESFVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14712 nt NT seq  +upstreamnt  +downstreamnt atgctaataccgataggagaagaggagctgtaccgagcacagcaagctgccagtggaggc aatcagagtcttagcagagctgactcctcaagagccatggctgaagggggtgaaggaggg gaagatgaaatacagttcctgcgaactgatgatgaagtagtacttcagtgtgttgccaac attcagaaagaacagcgaaagttctgcctggcagctgagggacttgggaatcgcctgtgc tttttggaaccaacttcagaagctaaatatgtgcctccagatctttgcatctgtaatttt gtgctggagcagtctctttctgtcagagccctacaggaaatgctggccagcacaggggaa aatgccagtgaaggggcagttcaaggaggtggtcacagaaccctgctgtatggccatgct atactacttcggcattcgttcagtggaatgtatttgacttgtttgtcaacatcaagatcc cagacagataaacttgcatttgatgtggggttacaagaaaatgcagcaggtgaggcatgc tggtggacaatacatcctgcttcaaaacagagatcagaaggagaaaaagttcgaattggc gatgatcttatcctggtcagtgtgtcctctgaaagatatctgcatctctccatgtcaaat ggaaatgttcaggtggatgcctcctttatgcaaacactctggaacgtccatcctacatgc tcaggaagtagcactgaagaaggatttctacttggtgggcatgtagtacgtttttttcat ggccatgatgagtgtttgacaatcccatctacagaccagagtgattcacagcagaagagg gtattgtatgaaataggaggagctggtgttcgtgcaagatccttgtggagagtggaaccc cttcgtataagttggagtggcagttacatcaaatggggacaacctttccgccttcgacac attacaacaggacagtacttggcacttactgaagaacaaggtctttcacttttagacaga gggaagtcagacacaaaatctacttccttttgttttagagcatcaaaggaaaaactggaa actgttcataaacgggacatagaaggcatgggagtcgccgaaataaagtatggtgattcc atttgttttgtccagcatgtaaccagtgcattgtggctgacttatcaagcacaggatgct aaagcaccacgtttaggacccttgaaaagaaaggttatattacaccaagaaggacatatg gatgatggtctaacattacaaaggtgtcaacatgaagaatcccaggctgctcgaatcatt cgcaatacttccagcttatttagccaatttataagtggaaacaacagaacagcagcaccc atcgccctgcctattgaggaggtacttgagaccctgcaagacctgattacttatttccag cctccagaagaagaactagaacatgaagataagcaaaacaaacttcgctcactcaaaaac agacaaaatttgttcaaagaagagggaatgctggcactagttttgaactgcatcgatcgc ttaaacgtctacaacagtgcagctcattttgcaggagttgcaagggaggaaagtggaaca gcatggaaggaaattctgaatctcctttacaaattgctagctgccctcattcgtggtaac agaaataactgcacccagttttccaataacctcgactggctaatcagtaaattggataga ctagaatcttcctcaggtattctggaagtattacattgcatcttgattgaaagtccagag gctttaaatttgatagcagaggaacatatcaagtctattatttcattgctggataaacat ggacgcaatcacaaggttcttgatgtgctttgctctctgtgtctctgtaatggagttgca gtgcgtgccaatcagaactgtatctgcgacaatctactcccccgaagagatttgctcttg caaacccgtttgattaatgatgtgacaagcatgaggccaaacatatttttgggggttgct gagggctctgcacagtataagaagtggtactttgaactaataatcgatcaggtagacgca tttttgacggcggaacccactcatctacgggttggctgggcctctacatcaggttatgct ccttatcctggaggtggagaaggatggggtggcaatggtgttggtgatgacctctactcc tatggttttgatggccttcatttgtggtctggtcgagtaccccgagctgtagcatctgtc aatcagcatttgttggcatctgatgacgtagttagctgctgcttggatttaggggtgccc agtatttcattccgcattaatgggcaacctgtacagggaatgtttgagaacttcagtgtc gatggacttttctatcctgtggtgagcttctctgcaggtatcaaggttcgtttcctactg ggtggacgtcatggagagtttaagttcctgcctcccactggatacgcaccctgctatgaa gctttgcttccaaaggagaagatgaaattggaaccagtaaaagagtataagagagattct gatggagttagggatttgctgggtacaacacaattcctctcccaagcttccttcattcct tgtccaatagataccactcagattgttttgcctcttcaccttgaaaagatcagggacaag ttggctgaaaatatccatgaactatggggaatgaataaaatagaacttggctggacctat ggcaagatacgggatgataataaaagacaacacccttgtctcgtggagttctcaaaatta cctgaaacagagaagaattataacctacaaatgtcaacagaaaccctaaaaactcttttg gcccttggatgtcatattgtgcatgctaatctggcagctgaggaagatcttaagaaagta aaacttcctaaaaattacatgatgtcaaatgggtataaacctgcccctctagatctttct gaagtgaaattgttaccttctcaagaagttttagttgataaacttgcagagaacgcacat aatgtctgggcaaaagacagaataaaacaaggatggacctatggcattcaacaggacctt aagaacaaacgaaatcctcgactggtgccatatgcattattagatgagcgtactaagaaa tcaaatagagacagtcttcgtgaagctgttcggacttttgctggttatggatataatatt gagccaccagaccaagaactagctgaccaaactgtggcaaaagtcagcattgataagata cgtttcttcagggtagaacagtcttatgcagtgacatctggaaagtggtactttgagttt gaagctgtgacgggtggagatatgcgtgttggctgggcaaggccaggctgccggccggac atagaattgggagctgatgaccaagcatttgtgtttgaaggcagcagaggccagcgttgg catctaggcagtggattctttggacgaaactggcaaccaggagatgtcgttggttgtatg ataaacttagatgacaagtccatgatctttactctgaatggggagttgcttataaccaat aaaggttcagaacttgcctttgcagactttgaaatagaaaagggtttagtcccaatttgc tcactgggtttgtctcagattggccgtatgaaccttggaatgaatgccagcaccttcaag tattatacaatgtgcggccttcaagagggttttgaaccttttgctgtcaacatgaaccga gatgtcgctatgtggtttagcaaacgcttaccaacttttgtcaacgtgccaaaaaatcat gctcatattgagataacgagaatcgatggaaccattgacagcccaccttgcttgaaagtg acccacaagacatttggcacacagaacagcaatgcagacatgatatattgccgtttgagc atgcccattgagttccattcatcctttaactatggcactggtgtgacaagtgcatctgct gatgctttccaaaaaagaaaacagaaccaagaaactgctcttcacactacaacatactat tactcagtgcgaatatttgctggtcaagacccatcctctgtctgggttggctgggtaaca cctgactaccacttttacagtgaaaatttcgacctaaacaaaaatagcacagtgacagtt actttaggtgatgaaagaggcagggttcatgaaagtgtgaagcgcagtaactgctacatg gtttggggtggagacatttctgctaattcccagagatcaagtcgcagtaatgttgattta gaaattggatgcctagttgacctgggtactggaatgttgtcattcacagccaatggaaaa gaccttggcacttgttatcaggttgaaccaaccacaaaattatttccagcagtttttata caacctatgagcacaaatttgtttcatttcgaacttggtaaattaaagaacaccatgcct ttatcagcagccatctttaaaagtgaagagaaaaatcccattcctcagtgccccccacgc cttgatgtgcaaacaattacacctgtgctctggagcagaatgcctaacagcttcctgaag gtggagactgagcgtatcagtgaacgccatggttgggtagtgcagtgtctggagccactg caaatgatggcacttcatattccagaggagaacaggtgtgttgatatattggagctatgt gaacaagaggatttgctgcaatttcactaccacactttaaaactctatagctcagtttgt gcactgggtaataatagagttgcttatgcactctgtagccatgtggacctatctcagtta ttttacacaatagataatcagtatttacctggactcttacgcgctggattctatgatcta cttatcagtattcatttggaacgtgccaaagaagccaagcttatgatgaacaatgaattt atcattccaattacagatgaaactagaaaaattgaattatatcctgatgaatcaaagaga catgggttaccaggagttgggcttagcacttgtttgaaaccaggttttaatttttctact ccttgtttcattgtggccagtgaagaacatcagaagcccagtccagagataccacttgag atactcaaaaccaaggccataagcatgctgacagaggcagtacactgtagtggtgttcat atccgagaccctgttggagggaaagttgaattccagtttgttcctgttcttaaacttata ggaactttacttgtaatgggggtttttgatgatgatgatgtgaaacagattttacttctt attgatcccaatgtgtttggagagcacaaggaagaaacagaagagaaaacggataaggag gaagttacacagattgaagaaaaagctgtggaagctggggaagaggcattaaaggaaact aaaccgccgatgaaaggcttagtgcagacaagattacctgaatctgttaaactccagatg tgtgagctactcaattatttctgtgactgtgagctgcgacacagggttgaagctattgta tcatttgcagataattatgtgtcaaagctgcaatataatcagaaatacaggtacaatgaa ctcatgcaagcattaaacatgtctgctgctttgactgccaagaagacgaaggaatttcgc tctccccctcaagaacagattaatatgttgctaaattttcaactgagagaagattgtccc tgtccagaggagattcgggaagagctatatgagtttcacgatgatcttctaattcactgt ggtattccactcgaagaagaagaggagatggatgaagacacttcctggatgggcaaactt cgttcactgatatacaaaatcaaaggcccaccaaaagcagaaaaaaaagagcctacagag gtggaggaaaagtctcccactactttgaaggaactcatatctcagactatggtgcgctgg gctcaggaagaccagatccaagatccagaattagtccggattatgttcaacctacttcgt aggcaatatgacagcatcggtgagctactgcaggctctgaggaaggcctacactattagt gctgcttctgtgcaggatacaatcaatttactagcagcactaggccagattcgctccctt ctcagtgtcagaatgggaaaagaagaggaattgcttatgattaatggattaggggatata atgaacaacaaggtgttttatcagcatcctaacttaatgagaatccttggtatgcatgag acagttatggaagtgatggtaaatgtgcttggaggagataaatctcagcagatcgctttt cctaagatggtggcaagctgttgtcggttcctgtgctacttctgtcgaatcagccgccaa aaccaaaaggccatgtttgagcatctaagttacttgctggaaaacagcagtgttgggctt gcatctccttctatgaggggttccactccactagatgttgcagctgcttctgtaatggac aataatgagcttgcactagctttggaagagccagacctggaaaaggttgtcacctacttg gctggttgtgggcttcagagctgccctatgctggtagctaaaggatatcctgacattgga tggaatccaatagagggtgaacgttacctatcattcttaagatttgctgtctttgttaac agtgaaagtgttgaggaaaatgctagtgttgttgtcaagctccttattcgacgcccagaa tgctttgggccagctcttagaggagaaggaggaaatggtttgctggcagctatgcaagga gctattaagatctcagagaacccaactcttgaccttccatctcagtgctataaaagagaa gtcagtgttgaagaagaggaggaggaagagattgtgcacatgggcaatgcaatcatgtcc ttttattcagctctgatagacttgcttggacgctgtgcaccagaaatgcatcttatccaa actgggaaaggagaagctattcgaatcaggtcaattcttcgttctcttgtgccaacagaa gatttggttgggattataagtataccactaaagctatcaacagttaacaaagatggtaca gtcaacgagccagacatgtctgcaagtttctgtcctgaccataaagcacccatggtgctg tttttggaccgtgtctatggtattaaggaccaaagcttcctcctccacctactggaggtt ggatttttacaagacttaagagcatctgcctctctggatacagtatccctgagcaccaca gaggcagctcttgcactaaatagatatatttgctcatctgtgcttccattactaacaaga tgtgctcccctcttttccggaacggagcattatgcctctctgattgattcaacacttcac acaatatatagactatccaagggacggtcccttacaaaagcacaaagagatactattgaa gaatgcttgcttgctatatgccaccatttacgtccctctatgctacagcagctattacga cggctagtttttgatgtacccttacttaatgaatactgtaaaatgccactcaagcttcta acaaatcattatgagcaattatggaaatattactgcctaccgtctggattggggagttac ggaattgcagcagaagaagagttacatttaactgagaaacttttctggggaatttttgat tccctctctcataagttcctatctctcctgcagaagtatgatccagagctcttccgaatg gccttgccttgtctaagtgctatagctggggctttgcctccagattatttagacaccaga attagagtaactttgaaaaagcagacttcagtggatccagagggaaactttgatcccaaa cctatcaacacaatcaaccttactcttcctgaaaaattggagtatattgttagcaagtat gctgaacattctcatgacaaatgggcctgtgacaagagtaatagtggatggaaatatggt gtttcactggatgaaaatatgaagacacatccgttaataaggcctttcaaaacattaact gaaaaggaaaaggaaatttatcgttggcctgccagagaatcgcttaaaaccatgttagcc atgggatggagtctagaaaggaccaaggaaggagaagcaatggtacagcagcgtgaaaat gaaaagctccgcagcatatcacagcctagccaaggaaatggatacagcccaacaccactt gatctttctaatgttgtactctctagggagctccagggaatggttgaggtagtagcagaa aactatcataacatttgggccagaaagaagaaaatggaattggagagcaaaggaggaggt agtcatcctttactggtaccttatgacaccttgacagccaaggagaagtctcgggaccgg gagaaggcacaagagctgtttaaattccttcaaatgaatggcatcgttgtatctaggggt ctgaaagatatggatttggatgcatcatccatggaaaagaggtttgcatttaagtttttg aagaagattctaaaatatgttgactctgctcaagagttcattgcacatttggaagccatt gtcaccagtggaaaaacagagaaatcaccacatgaccaagaaattaaattctttgccaaa gttctcctaccattagttgaccagtactttaccaatcactgcctgtacttcctgtcttct ccaattaagtcactcagtagcagtggatatgcttccaataaggaaaaagaaatgttggca agcctattctgcaaacttgctgctcttgttagacataggatttcactttttgggagtgat gctactacaatggtgagctgcctgcacatcttggctcagacactggatacacgaaccgtc atgaaatcaggctcagagttggttaaagctggattacgtgcattctttgaaaatgcggct gaagatctggaaaagactttagaaaatcttaaacttgggaaatttacccattcacgaaca caaattaaaggtgtctcacagaacatcaactatactacagtggcattattgcctatattg acatcaatttttgaacatattgcgcagcatcagtttggtgttgatttacttttgggtgat gtgcaagtttcatgttatagaattctttgtagcctatattcccttgggactggaaagaac atctatgttgaaagacagcgtccagcacttggtgagtgcttagcatcccttgcagcagcc attccagtcgcattccttgaaccttctctgaacagttacaacccactctctgtcttcaac acaaaaactgctagagagagagccattttaggtatgccagatacagttgaagagatgtgt ccagatatccctcagctagatggattaatgaaggaaattaatgatttagcagagtctggg gccagatacactgaaatgccccacgtgattgaggttaccttacctatgctatgcaactat ttatcgtactggtgggaaagagggtctgagaatatgcctaaaagtgctggaccctgctgt acaatggtaacctctgagcaactcagcatcattctgggaaacattctgaaaatcatcaac aacaacctgggaatagatgaagcatcttggatgaagagaattgcagtttatgctcaacct atcatcagcaaagccaggcctgatctgttgaaaacccactttattccaactctggagaaa ctaaagaagaaagctataaagatagtaatggaggaggagcaactaagagcagacagtaaa agtgatacccaagaagcagagctactcattctagatgagtttgcagttctttgccgagac ctctatgccttctatccaatgctgatacgttatgtagacaacaacagagcaaattggctc aagaaaccagatgcagattctgatgaacttttccaaatggtagctgaggtttttatcttg tggtgtaaatcacataacttcaagagagaagaacaaaattttgtgattcagaatgaaatc aacaatttggcatttttaacaggcgacagcaagagcaagatgtctaaatctggaggacaa gaccaagagcgaaagaaattgaagcgtagaggggatttgtattcaatacagacatccttg attgtagctgcacttaaaaagatgcttcctattggtttgaatatgtgcactcctggagat caagagctgatttctttggctaagattagatacagtcatagggacacagacgaagaagtc aaagaacatttacgtaacaacttgcatttgcaggaaaagtctgatgacccagctgtgaaa tggcagttgaacctgtacaaggacattttgaaaagtgaggagcctgctgatcctgagaaa gctgtggaacgggtgcagagaatctcagcagctgtctatcatctggagcaggtcgagcaa ccattaagatcaaaaaaagctgtttggcacaaactcttgtcaaaacaacgcaaaagggcc gttgtcgcttgtttcaggatggcaccgttgtacaatctgccaagacacaaaattagcact ttcttcctgagcacctttcaacgtgtttggctggaaaaagtacatgaaaaaactcagtat gacaggcttatactcatgttaacgacacctccaaaaaaggatgaggaggaggtggaagag actgaaaaacaccctgatccacttcatcagataatcctccatttcagtcgcaatgctctc actgagagaagcaaactagatgatgatcctttgtacactgcctattcagccatgatggcc aagagctgtcaaagtgaagaagaggaagaagaggatgaagaaaaagagaagacatttgag gagaaagaaatggaaaagcagaaaactctttatcagcaagctcgtctgcacgaccgtgga gctgctgagatggttcttcagatgattagtgcaagcaaaggtgaactgggccccatggtt attgaaacattaaaacttggcattgccattctaaatgctggtaataccttagttcagcag aaaatgttagactaccttaaagagaagaaggatgctggattttttcagagtctctctggc ttaatgcaatcttgcagtgttcttgacttgaatgcatttgaaagacagaataaagcagaa ggtcttggaatggttactgaagaaggaactctcatcgttcgtgagcgtggtgagaaagtg ctacagaatgatgagtttactcgagatctgtttagatttttacagctgctttgtgaaggt cataacaatgattttcagaatttcctgcgtactcagatgggcaacactacaaccgtgaat attatcatcagcactgttgactatctcttacgtcttcaggaatcaattagtgacttctat tggtactattcaggaaaaaacgtgattgatgaatctggacagcgtaacttctctaaagct ttggctgttaccaaacaaattttcaactcacttacagaatatatccagggaccttgcata ggtaaccagcagagtctggctcacagtaggctgtgggatgcagttgttggcttccttcat gtctttgctaacatgcaaatgaaactctctaaggattccagtcagattgaattacttaag gaattgttggatctcctgaaggatatggttgtgatgctcttgtcactacttgaaggtaat gttgtaaatgggactattggaaaacagatggtggacacactggtagaatcatctagtaat gtagaaatgatcttgaagttcttcgacatgttcctcaaattgaaagacctaaccagctca gatgctttcaaagactatgatccagatggtaaaggcatcatctcaaagaaagaattccag aaagcaatggaaggtcagaaacaatacacacagtcagaacttgaattccttctgtcctgt gcagaagctgatgaaaatgacatgtttaattatgttgattttgtggacagattccatgag ccagccaaagacattggatttaatgtggcagtcttgttaactaacctttcagagcacatg ccaaatgattcacgccttcagtgcttactagatccagcagcaagtgtacttaattacttt gaaccttaccttggccgtattgaaataatgggtggagccaagaaaattgaaagagtttac tttgaaatcagtgagtccagtagaatgcagtgggagaagccacaggtgaaagaatccaaa aggcagttcatatttgatgttgtaaacgaaggcggggaacaagagaaaatggagctgttt gtgaatttctgtgaggacacaatctttgaaatgcagttagcttctcagatctctgaatca gattcagctgaacgacctgaagaggaggaagaggatgagccttattatgtaatggaagtt ggagatgatgaggaagaagaaaaatctctggaatcagcttcagcttttgcaatggcctgt gttgcagtgaagaggaatgctgccaactttttaaaaatggtcactttaaggaaccttagg aaacaatacagaaaagttagaaagatgactataaaggaattggtgaaagtgtttttctcc tttttctggatgctatttgtagggttattccagttgttcttcaccatcgtatgggggatt ttccagattctctggagtactgtgtttgggggtggcttggttgaaggagccaaaaacatc aaagttaccaaaatattaggggacatgcctgacccaacacagtttggaatccatgatgac atcatggaagctgagaaggttgaaggcattgagcatggcattagagttgaacttgtgcag tttgtgaaaggtgaaaaaggagaaacagacataatgtcggatatttttggcattcatgca aagaaagaaggtggctcaaaacatggtcatgatgctgggcttggtgatgttgcagaaata gttggtacagatactcctccctctttggaaagcactgttcgtaggaaaagaaaagcacag atatctgaaatagcaaaagaagatgaaacagaaacaaaagcagaatccgagaaggctgac atggaagatggtgagaaagaagacaaagcaaaggaagaagtacaatctgagcatttggga aaggaggaaaccaagaaaaagaaacgaaggcatggacaaaaaatagagaaacctgaggca gttatggctaatttttttaaagtcgtggaaatttatcaaacgaaaatgctgcattacttg gctagaaatttctacaacttaagatttcttgctctgtttgttgcatttgccatcaacttt atactgctattctacaaggtgacagaagaaccattagatgagttagaggaagactctgat ctatggaattcatttgaagaagaggaagaggaagagggagtggtgttttttgttttacaa gagagtacaggttacatggcaccaacactcagggctctagcagttattcatactatcatc tcctttgtctgtgtgattggatactattgtctaaaggttcccctggttgtatttaagcgc gaaaaggaaatcgccaggaagttggaatttgatggtctgtacattacagaacagccctca gaggatgacattaaaggacaatgggatcgcctggtcataaacactccatcctttcctaac aattactgggacaagtttgtaaaacggaaggttattaacaaatatggtgatttgtatgga gcagagcgcatagctgaactcttggggttggacaaaaatgctcttgatttcagtccagtg gaagagactgaaccagaggaagcatctcttgtatcatggttaagctctattgatacaaag taccacatctggaagcttggagttgttttcactgacaattccttcttgtacttagcttgg tacacaactatgtctatccttggccattacaacaacttcttctttgctgctcacttgctg gatattgctatgggtttcaagactctacgaaccattctgtcttctgtaactcacaatggc aaacagcttgtactgactgtaggattgttggctgtagtagtctacctttacactgttgtg gcattcaacttcttccgcaagttttacaacaaaagcgaagatgaagatgagccagacatg aaatgtgatgacatgatgacatgttacctgttccacatgtatgtgggtgtgagagctggt ggtggcattggggatgaaattgaagaccctgctggggacccttatgaaatgtatcgaatt gtctttgacattacattcttcttcttcgtcattgtcatcctactggctatcattcaaggt ctgattattgatgcctttggtgaattaagagatcagcaagaacaagtgagagaagatatg gagaccaaatgtttcatttgtggaattggtaatgactattttgacacgaccccacatggt tttgaaatgcatactttacaagagcacaatttggcaaactatctcttctttctaatgtat ctcattaataaggatgaaactgagcacactggtcaggaatcatttgtatggaaaatgtac caagaaagatgctgggatttcttcccagctggagattgcttccgtaaacaatatgaggat caacttggataa

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