KEGG   Couchioplanes caeruleus: COUCH_02345
Entry
COUCH_02345       CDS       T08133                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
ccaz  Couchioplanes caeruleus
Pathway
ccaz00290  Valine, leucine and isoleucine biosynthesis
ccaz00620  Pyruvate metabolism
ccaz01100  Metabolic pathways
ccaz01110  Biosynthesis of secondary metabolites
ccaz01210  2-Oxocarboxylic acid metabolism
ccaz01230  Biosynthesis of amino acids
Module
ccaz_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ccaz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    COUCH_02345 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    COUCH_02345 (leuA)
Enzymes [BR:ccaz01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     COUCH_02345 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer TSC21
Other DBs
NCBI-ProteinID: UQU65209
LinkDB
Position
complement(489969..491708)
AA seq 579 aa
MSSDVNADPIARQSPSRMPFERYIPYQQQFAVDLPDRRWPSRRVEAAPRWCAVDLRDGNQ
ALIDPMSPERKRRMFSLLVAMGYKEIEVGFPAASQTDYDFVRQLIEQDLIPDDVTIQVLV
QCREHLIDRTFESIRGAKRAIVHFYNSTSTLQRRVVFGLDKAGITDIATTGARLCQKYAE
IHTPDTEIFYEYSPESYTGTELDYALEICSAVIDVIDPTPDRPLIINLPATVEMATPNVY
ADSIEWMDRHLPRRESIILSLHPHNDRGTAVAAAELGVLAGADRVEGCLFGNGERTGNVD
LVTLGLNLFSQGIDPMIDFSDIDEIKRAVEYCNQLPVHERHPYVGDLVYTAFSGSHQDAI
KKGLAALQEDAAEAGVDVDKFAWGVPYLPIDPKDLGRTYEAVIRVNSQSGKGGVAYIMKE
EHKLDLPRRLQIEFSGVVQHVTDAEGGEVGPQQMWDIFASEYLVDHQQFGIVELERYTTA
TVDGKVEIDAEVRHRNTRRPVVGLGNGPIDAYVQALEPLGIKVRVLDYAEHALTSGEDAQ
AAAYVECEINDRTVWGVGLDANIVTASIKAVTSAVNRVR
NT seq 1740 nt   +upstreamnt  +downstreamnt
atgtccagcgacgtgaacgccgatccgatcgcccggcagagccccagccggatgccgttc
gagcgctacatcccttaccaacaacagttcgccgtcgacctgcccgaccgccggtggccg
tcgcggcgcgtcgaggccgccccgcgctggtgcgcggtcgacctgcgtgacggcaaccag
gccctgatcgacccgatgtcccccgagcgcaagcggcgcatgttcagcctgctcgtcgcg
atgggctacaaggagatcgaggtcggcttcccggccgccagccagacggactacgacttc
gtccgccagctcatcgagcaggacctgatccccgacgacgtgacgatccaggtgctggtc
cagtgccgcgagcacctgatcgaccgcacgttcgagtcgatccgtggcgccaagcgcgcg
atcgtgcacttctacaactcgacctcgacgctgcagcgccgcgtcgtcttcggcctggac
aaggccggcatcaccgacatcgcgacgaccggggcccggctctgccagaagtacgcggag
atccacaccccggacaccgagatcttctacgagtactcgccggagtcgtacacgggcacc
gagctggactacgcgctggagatctgctcggcggtcatcgacgtcatcgaccccaccccg
gaccgcccgctgatcatcaacctgccggcgacggtcgagatggccacccccaacgtgtac
gcggacagcatcgagtggatggaccgccacctgccccgccgcgagagcatcatcctcagc
ctgcacccgcacaacgaccgcggtacggccgtggccgccgccgagctgggcgtgctggcc
ggcgcggaccgcgtcgagggctgcctgttcggcaacggggagcgcacgggcaacgtcgac
ctggtcacgctgggcctgaacctgttctcccagggcatcgaccccatgatcgacttctcg
gacatcgacgagatcaagcgcgcggtcgagtactgcaaccagctgccggtgcacgagcgg
cacccgtacgtcggcgacctggtgtacaccgcgttctccggctcgcaccaggacgcgatc
aagaagggcctggcggcgctgcaggaggacgcagcggaggccggcgtcgacgtggacaag
ttcgcgtggggagtgccgtacctgccgatcgacccgaaggacctcggacgcacgtacgag
gccgtcatccgggtcaactcgcagtccggcaagggcggcgtggcgtacatcatgaaggag
gagcacaagctcgacctgccgcgccggctgcagatcgagttctccggcgtggtgcagcac
gtcaccgacgccgagggcggcgaggtcggcccgcagcagatgtgggacatcttcgccagc
gagtacctcgtcgaccaccagcagttcggcatcgtcgagctggagcgctacacgacggcc
accgtggacggcaaggtcgagatcgacgcggaggtgcggcaccgcaacacccgccgcccg
gtcgtcggcctcggcaacggcccgatcgacgcgtacgtgcaggcgctcgagccgctgggc
atcaaggtccgggtcctggactacgccgagcacgcgctgacgtccggtgaggacgcgcag
gccgccgcgtacgtggagtgcgagatcaacgaccgcacggtgtggggcgtgggcctcgac
gcgaacatcgtcaccgcctcgatcaaggccgtgaccagcgcggtgaaccgcgtccgctga

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