Couchioplanes caeruleus: COUCH_02345
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Entry
COUCH_02345 CDS
T08133
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ccaz
Couchioplanes caeruleus
Pathway
ccaz00290
Valine, leucine and isoleucine biosynthesis
ccaz00620
Pyruvate metabolism
ccaz01100
Metabolic pathways
ccaz01110
Biosynthesis of secondary metabolites
ccaz01210
2-Oxocarboxylic acid metabolism
ccaz01230
Biosynthesis of amino acids
Module
ccaz_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ccaz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
COUCH_02345 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
COUCH_02345 (leuA)
Enzymes [BR:
ccaz01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
COUCH_02345 (leuA)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
TSC21
Motif
Other DBs
NCBI-ProteinID:
UQU65209
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Position
complement(489969..491708)
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AA seq
579 aa
AA seq
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MSSDVNADPIARQSPSRMPFERYIPYQQQFAVDLPDRRWPSRRVEAAPRWCAVDLRDGNQ
ALIDPMSPERKRRMFSLLVAMGYKEIEVGFPAASQTDYDFVRQLIEQDLIPDDVTIQVLV
QCREHLIDRTFESIRGAKRAIVHFYNSTSTLQRRVVFGLDKAGITDIATTGARLCQKYAE
IHTPDTEIFYEYSPESYTGTELDYALEICSAVIDVIDPTPDRPLIINLPATVEMATPNVY
ADSIEWMDRHLPRRESIILSLHPHNDRGTAVAAAELGVLAGADRVEGCLFGNGERTGNVD
LVTLGLNLFSQGIDPMIDFSDIDEIKRAVEYCNQLPVHERHPYVGDLVYTAFSGSHQDAI
KKGLAALQEDAAEAGVDVDKFAWGVPYLPIDPKDLGRTYEAVIRVNSQSGKGGVAYIMKE
EHKLDLPRRLQIEFSGVVQHVTDAEGGEVGPQQMWDIFASEYLVDHQQFGIVELERYTTA
TVDGKVEIDAEVRHRNTRRPVVGLGNGPIDAYVQALEPLGIKVRVLDYAEHALTSGEDAQ
AAAYVECEINDRTVWGVGLDANIVTASIKAVTSAVNRVR
NT seq
1740 nt
NT seq
+upstream
nt +downstream
nt
atgtccagcgacgtgaacgccgatccgatcgcccggcagagccccagccggatgccgttc
gagcgctacatcccttaccaacaacagttcgccgtcgacctgcccgaccgccggtggccg
tcgcggcgcgtcgaggccgccccgcgctggtgcgcggtcgacctgcgtgacggcaaccag
gccctgatcgacccgatgtcccccgagcgcaagcggcgcatgttcagcctgctcgtcgcg
atgggctacaaggagatcgaggtcggcttcccggccgccagccagacggactacgacttc
gtccgccagctcatcgagcaggacctgatccccgacgacgtgacgatccaggtgctggtc
cagtgccgcgagcacctgatcgaccgcacgttcgagtcgatccgtggcgccaagcgcgcg
atcgtgcacttctacaactcgacctcgacgctgcagcgccgcgtcgtcttcggcctggac
aaggccggcatcaccgacatcgcgacgaccggggcccggctctgccagaagtacgcggag
atccacaccccggacaccgagatcttctacgagtactcgccggagtcgtacacgggcacc
gagctggactacgcgctggagatctgctcggcggtcatcgacgtcatcgaccccaccccg
gaccgcccgctgatcatcaacctgccggcgacggtcgagatggccacccccaacgtgtac
gcggacagcatcgagtggatggaccgccacctgccccgccgcgagagcatcatcctcagc
ctgcacccgcacaacgaccgcggtacggccgtggccgccgccgagctgggcgtgctggcc
ggcgcggaccgcgtcgagggctgcctgttcggcaacggggagcgcacgggcaacgtcgac
ctggtcacgctgggcctgaacctgttctcccagggcatcgaccccatgatcgacttctcg
gacatcgacgagatcaagcgcgcggtcgagtactgcaaccagctgccggtgcacgagcgg
cacccgtacgtcggcgacctggtgtacaccgcgttctccggctcgcaccaggacgcgatc
aagaagggcctggcggcgctgcaggaggacgcagcggaggccggcgtcgacgtggacaag
ttcgcgtggggagtgccgtacctgccgatcgacccgaaggacctcggacgcacgtacgag
gccgtcatccgggtcaactcgcagtccggcaagggcggcgtggcgtacatcatgaaggag
gagcacaagctcgacctgccgcgccggctgcagatcgagttctccggcgtggtgcagcac
gtcaccgacgccgagggcggcgaggtcggcccgcagcagatgtgggacatcttcgccagc
gagtacctcgtcgaccaccagcagttcggcatcgtcgagctggagcgctacacgacggcc
accgtggacggcaaggtcgagatcgacgcggaggtgcggcaccgcaacacccgccgcccg
gtcgtcggcctcggcaacggcccgatcgacgcgtacgtgcaggcgctcgagccgctgggc
atcaaggtccgggtcctggactacgccgagcacgcgctgacgtccggtgaggacgcgcag
gccgccgcgtacgtggagtgcgagatcaacgaccgcacggtgtggggcgtgggcctcgac
gcgaacatcgtcaccgcctcgatcaaggccgtgaccagcgcggtgaaccgcgtccgctga
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