Ruminiclostridium cellulolyticum: Ccel_0499
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Entry
Ccel_0499 CDS
T00835
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
cce
Ruminiclostridium cellulolyticum
Pathway
cce00230
Purine metabolism
cce01100
Metabolic pathways
cce01110
Biosynthesis of secondary metabolites
Module
cce_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
cce00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
Ccel_0499
Enzymes [BR:
cce01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
Ccel_0499
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
NapD
Motif
Other DBs
NCBI-ProteinID:
ACL74881
UniProt:
B8I6I9
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Position
576490..580260
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AA seq
1256 aa
AA seq
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MKSTVKRLFVVKKHPYDVEAQGLLKDFRETLGIESLESLKIVNRYDVEGISDSEYQLARN
TIFSEPTVDSAYDEEFKIPSNCRAFAVEFLPGQYDQRADSAAQCIQLLTQGDRPEINTAR
VIVLQGSINEKEFNSIKEYYINPVESREAKMEKPETLKAEVEQPEDVATLEGFTSMNEKQ
LSELLREMGFAMSFDDIIFCQNYFKNSEKRDPSVTEMRMIDTYWSDHCRHTTFLTCIDSV
KFEKGRFTEIIEETYKDYIEKREDIYKDRNDKDICLMDIALMAMKALKKQGKLNDLDLSD
EINACSIVVNADINGKNEEWLVMFKNETHNHPTEIEPFGGAATCLGGAIRDPLSGRVYVY
QAMRVTGSGDPRTKLEDTIQGKLPQKKITTGAASGYSSYGNQIGLATGQVAEIYDEGYVA
KRMEIGAVIGAAPRKNVVRMQPEAGDKIILLGGRTGRDGCGGATGSSKAHTEESLITCGA
EVQKGNAPTERKIQRLFRNPNASTLIKRCNDFGAGGVSVAIGELADGLEINLDAVPKKYE
GLDGTELAISESQERMAVVVEACDVEKFIGFAAEENLEAVVVAEVKAEPRLKMSWRGKQI
VDLSREFLNSNGAKQRIDIEISAPDEETYFDKCNEIEIDNLKEYWIKNLQNLNRCSQKGL
VERFDSTIGANTVLMPFGGKTQLTPAEGMAAKLPLMEGDTTTGTLMSFGYNPDIAKWSPF
HGAVYAVVESIAKIVAMGGDYSKARLTLQEYFEKPGKDAKRWGKPLSALLGAYYAQMKLG
TAAIGGKDSMSGSFMDMDVPPTLVSFAVNTVNVDNVISNEFKGVGSRVVLLKVKLDDNIL
PDFDELDRVYSRVNKLAKEKAILSASSVRSGGIAEIISKMAFGNMIGFTLKGIADVSLLF
KPFYGSLILEIPENIDLTKALEGLRYTVLGVTTANSEININGTVIDLGELSHKWQEPLEK
VFPTRVSEVQGTTVQYNFEAKTKAKPSVKIAKPRVFIPVFPGTNCEYDTKKVFENAGGIV
ETMVIKNMTHKDIEESIKRMEKLIDNSQIIMIPGGFSAGDEPEGSGKFIATAFRNPVVSE
AVMKLLKNRDGLVLGICNGFQALIKLGLLPFGEIREIDEVCPTLTFNTIGRHQSCLVKTR
IASNLSPWLNNVKVGDIHTIAISHGEGRFTANSEVMAGLEANGQIATQYVDLNGKPTLDI
SFNPNGSINAVEGITSPDGRVFGKMGHSERIGTNLYKNVPGEKDQQLFRAGIEYFG
NT seq
3771 nt
NT seq
+upstream
nt +downstream
nt
atgaaaagtactgtaaaaagactatttgttgtaaagaaacatccttatgacgttgaagca
cagggacttttgaaggacttcagagaaacgctgggaatagagtcattggaatctttaaag
attgtcaatagatatgatgtagaaggcataagcgattctgaatatcaactggcaagaaac
accatattttctgaaccgacagttgattctgcgtatgatgaggagtttaaaattccttca
aactgcagagcttttgctgttgagtttcttcccggacaatatgatcaaagagcagattcg
gctgctcaatgtatacagcttttaacacaaggcgacaggcctgaaattaatactgccaga
gtaattgttttacaaggcagcataaacgaaaaagaattcaattccataaaagaatactat
ataaatcccgttgaaagcagagaggctaaaatggaaaaacccgaaactcttaaagctgag
gttgagcagcctgaggatgttgctactcttgagggatttacatccatgaatgaaaaacaa
ctctcggagcttttaagggaaatgggttttgcaatgtcttttgacgacataattttctgc
cagaactacttcaaaaactcggaaaagcgtgacccttcagtaacagaaatgagaatgata
gacacttactggtcggatcattgcagacatacaacttttcttacctgtattgatagtgta
aagtttgaaaaaggcagatttacagaaatcattgaggagacctacaaggactacattgaa
aaaagagaggatatctacaaggaccgtaatgacaaggatatatgccttatggacattgct
cttatggcaatgaaagcattgaaaaagcagggaaaattgaatgaccttgacctctcagat
gaaataaatgcatgtagcatagttgtcaatgcagacataaacggaaaaaatgaagagtgg
cttgtaatgtttaaaaatgagacacacaaccatcctacggaaatcgaaccctttggtgga
gctgcaacatgccttggaggagctatcagagacccgttgtcgggaagagtttatgtatat
caggcaatgagagtaacaggaagcggcgaccccaggacaaagcttgaagacacaatacaa
ggaaaacttccgcaaaagaaaataaccacaggagccgcttctggatacagttcctacggg
aaccagataggtcttgctacagggcaggtagctgaaatatacgacgagggctacgttgca
aaaagaatggaaattggtgctgtaataggtgcagctccaagaaaaaatgtggtaaggatg
cagcctgaagcgggggataagataatactccttggagggagaacgggaagagacggctgc
ggaggagcaacgggttcgtctaaagcacatacggaagaatctttgataacatgcggtgct
gaggtacagaagggtaatgcccctacagagagaaaaatacaacgattattcagaaatccc
aatgcaagcacattaataaaaagatgtaatgacttcggtgcaggcggtgtttccgttgca
ataggagaattggcagatggtcttgaaataaatcttgatgctgtaccaaagaagtatgaa
ggattggatggaacagaactggcaatttcggagtcacaggagcgtatggctgttgttgtt
gaagcctgcgatgtggaaaaattcataggctttgcagcagaagaaaatctggaagctgtg
gttgtcgcagaagttaaggcagaacctaggcttaaaatgtcatggagaggaaagcagata
gttgacttaagccgtgaattcctgaattcaaatggtgcaaaacaacggattgacatagag
atttctgcaccggatgaagaaacatattttgataaatgcaatgaaatagagatagacaat
ttaaaagaatactggattaaaaacctgcaaaatcttaacagatgcagtcaaaagggtcta
gttgaaagatttgattcaacaataggtgcaaatacagtacttatgcctttcggcggaaaa
acacagcttacccctgcggaaggaatggctgcaaagctgccccttatggagggtgacaca
acaaccggaacacttatgtcttttggatacaatccggacatagcaaaatggagtcctttc
catggagcagtatatgctgttgtagaatctattgcaaaaattgtggcaatgggtggtgat
tacagcaaggcaaggcttacacttcaggaatattttgaaaagccgggaaaagatgcaaag
cgttggggaaaaccgcttagtgccttacttggtgcgtactatgcacagatgaagctggga
acggcagctatcggcggaaaggacagtatgtcgggaagctttatggacatggatgttccg
ccgacactggtatctttcgctgtaaacactgttaacgtggacaacgttatttccaatgaa
ttcaagggtgtaggaagcagggttgtactgctcaaagtaaaacttgatgataatatactt
cctgattttgatgagcttgacagagtgtatagtcgtgttaacaagctagctaaagaaaaa
gccatattatctgcaagttccgtaagatctgggggtattgctgaaataatcagtaaaatg
gcatttggtaatatgattggatttacacttaaagggatagcggatgtttcacttctgttt
aaacccttctatggttctttaatccttgaaatacctgaaaatatagatttgacaaaagca
ctggaaggacttagatacactgtattgggtgttaccacagccaattctgaaattaacata
aacggtactgtaattgatcttggggagctttcccacaagtggcaggaacctttggaaaag
gtgttccctacaagagtaagtgaagtccagggaactacagttcaatacaattttgaagca
aaaacaaaagctaaaccttccgtaaagatagcaaaaccaagagtattcattcccgtattt
ccgggaacaaactgtgaatacgatactaaaaaggtatttgaaaatgccggcggaatcgta
gaaacaatggtaataaaaaatatgactcataaggacatcgaagagtctataaagagaatg
gaaaaactcattgataattctcagattatcatgatacccggaggcttcagtgcaggtgat
gaacctgaaggatcaggtaagtttattgctacagcatttagaaatcctgttgtcagtgaa
gctgtcatgaagcttttgaagaatagagacggattagttttaggtatatgtaacggattt
caggcattgattaagctcggacttcttccttttggagaaataagagaaattgacgaggta
tgtcctacattgacatttaataccataggacgacaccagtcctgtcttgtaaaaacgaga
atagcatcaaacctttcaccatggctgaacaatgtaaaggttggtgacatccatacaata
gcaatatcccacggtgaaggaaggtttactgcaaacagtgaggttatggctggtttggag
gcaaacggacagattgcaacacagtatgttgatttaaatggaaagcctacattagacatt
tcatttaatcctaatggctcaattaatgctgtggaaggtattacaagtccggatggaaga
gttttcggtaaaatgggacattcggaaagaataggtacaaacctatataaaaatgtaccg
ggtgaaaaagaccagcaattgttccgtgctggaattgagtattttggttga
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