Cinclus cinclus (white-throated dipper): 134042431
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Entry
134042431 CDS
T10813
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
ccic Cinclus cinclus (white-throated dipper)
Pathway
ccic00270
Cysteine and methionine metabolism
ccic00480
Glutathione metabolism
ccic01100
Metabolic pathways
ccic01240
Biosynthesis of cofactors
ccic04216
Ferroptosis
Module
ccic_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
ccic00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
134042431 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
134042431 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
134042431 (GCLC)
Enzymes [BR:
ccic01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
134042431 (GCLC)
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Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
134042431
NCBI-ProteinID:
XP_062345729
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Position
3:complement(23388158..23423061)
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AA seq
636 aa
AA seq
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MGLLSQGSPLSWEETRRYAEHVRRHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVCLALRGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPDYKPTPVEEGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDRNTPSPFIETFPNDDGEAAKAAKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEQLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVVDGCGSAQNGTGTNTEEYTLMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEINY
SLMWKCNQIAQGQAECPELLGVGFNKKQSGNKTDSL
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcaaggctcgccgctgagctgggaggagacgcggcggtacgcggag
cacgtgcggcggcacggcatcctccagttcctccacatctaccgcgccctgcgcgaccgc
cacaaggacgtgctcaagtggggcgacgaggtggaatatatgttggtgaaatttgaccat
gaaaacaagaaagtgtgtttggcactccgtggtgaagaagttcttcaaacgctgcaagac
aagggggagaaggtaaaccccaatcacccaacactctggagaccagaatatggaagttac
atgattgaaggaacacctggacagccatatgggggaaccatgtctgaattcaacactgtg
caagacaacatgaggaaaagacggcaagaggctgcttctgtactcaaagaaaatgaggct
gtttgcacagtgacatcatttccaaggttaggctgtcctgggtttacactgccggattat
aagccaacaccagtagaagaaggagcttcaaaatctctcttttttccagatgaagccatc
aataaacatcctagatttagtacactgaccagaaacattcgacacagaaggggagagaag
gttgtgataaatgtaccaatatttaaagataggaacacgccatcacctttcattgaaaca
tttcctaatgatgatggagaagcagcaaaggcagccaagccagactacatatatatggat
gctatgggttttggaatgggaaactgttgtctccaggtgacatttcaggcttgcagcatt
tccgaagcaaggtatctctatgatcagctagctacaatttgtcccattgtgatggcgttg
agtgctgcatctccattctacagaggctacgtgtctgacattgactgtcgctggggagtg
atctctgcttccgtggatgatcgaacacgggaggagagaggcctagagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcagctaata
aaggaaggtattgaccaccttttggcacagcatattgcacacttgttcattcgagaccca
ctgactttgtttgaggagaaaatacatctagatgatgcaaatgaatccgaccattttgag
aatattcagtctacaaactggcagacaatgaggtttaagccaccacctccaaattcagat
attggatggagagtggaattcagacctatggaggtccagttaacagactttgaaaactct
gcatatgttgtgtttgtggtattgctaacgagagtgattctgtcatataaactggatttt
ctcattcctttgtccaaggtggatgaaaacatgaaggtggcccagaaaagagatgctgta
cgacagggcatgttttacttcagaaaagatatatgcaaaggtggaaatgctgttgtggat
ggatgtggctctgcacagaatgggacaggcaccaacacagaagagtacaccttaatgagc
attgatacaattatcaatgggaaggaaggagtctttcctggtttgatcccaattttgaat
tcctatcttgaaaacatggaagtggatgtagacacaagatgcaccatcctaaactatctg
aagctaataaaaaagagagcctctggagaattaatgacagttgctcgatggatgagggaa
ttcatcgcacagcatccggactacaagcaagacagtgtgataactgatgaaattaattac
agccttatgtggaaatgtaaccaaattgctcaaggccaggcagagtgtcctgaactattg
ggggtaggatttaataagaaacaaagtggaaacaaaactgactctttgtaa
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