KEGG   Cinclus cinclus (white-throated dipper): 134050657
Entry
134050657         CDS       T10813                                 
Symbol
SMURF1
Name
(RefSeq) E3 ubiquitin-protein ligase SMURF1
  KO
K04678  E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
Organism
ccic  Cinclus cinclus (white-throated dipper)
Pathway
ccic04120  Ubiquitin mediated proteolysis
ccic04137  Mitophagy - animal
ccic04144  Endocytosis
ccic04340  Hedgehog signaling pathway
ccic04350  TGF-beta signaling pathway
ccic04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:ccic00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    134050657 (SMURF1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    134050657 (SMURF1)
   04350 TGF-beta signaling pathway
    134050657 (SMURF1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    134050657 (SMURF1)
   04137 Mitophagy - animal
    134050657 (SMURF1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    134050657 (SMURF1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccic04131]
    134050657 (SMURF1)
   04121 Ubiquitin system [BR:ccic04121]
    134050657 (SMURF1)
   03029 Mitochondrial biogenesis [BR:ccic03029]
    134050657 (SMURF1)
Enzymes [BR:ccic01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     134050657 (SMURF1)
Membrane trafficking [BR:ccic04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    134050657 (SMURF1)
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    134050657 (SMURF1)
Ubiquitin system [BR:ccic04121]
 Ubiquitin ligases (E3)
  HECT type E3
   134050657 (SMURF1)
Mitochondrial biogenesis [BR:ccic03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    134050657 (SMURF1)
SSDB
Motif
Pfam: HECT WW C2 DUF7350
Other DBs
NCBI-GeneID: 134050657
NCBI-ProteinID: XP_062359850
LinkDB
Position
16:3156789..3198051
AA seq 729 aa
MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDP
KWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCK
LNPTDTDAVRGQIVVSLQTRDRIGTGGSVVDCRGLLENEGTVYEDSGPGRPLSCFMEEPA
PYTDTTGAAGGGGCRFLESPSQDQRLQAQRLRTPEVRAHVQTPQNRPHGHQSPELPEGYE
QRTTVQGQVYFLHTQTGVSTWHDPRIPRDLNSVNCDELGPLPPGWEVRSTVSGRIYFVDH
NNRTTQFTDPRLHHIMNHQCQLKEPSQQPLPAPNEGSLEEGEELPAQRYERDLVQKLKVL
RHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAR
EWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSINPDHLSYFHFVGRIMGLAVFHGHY
INGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILENDITPVLDHTFCVEHNAFGRI
LQHELKPNGRNIPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQ
KELELIIGGLDKIDLNDWKSNTRLKHCMADSNIVKWFWQAVETFDEERRARLLQFVTGST
RVPLQGFKALQGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAV
EETCGFAVE
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgtcgaatcccggtacccgccggaacggatccagcatcaagatccgcctcacagtatta
tgtgccaagaatctcgcaaagaaagatttcttcagacttcctgacccatttgctaaaata
gttgtggatgggtcaggtcagtgccattccactgacactgtgaagaacacgttggacccc
aagtggaaccagcattacgatctatacgttgggaaaacagattccataaccatcagtgta
tggaaccataaaaaaatccataagaaacagggagctggcttcctggggtgtgtccgactc
ctctccaatgccatcagcaggctaaaagatactggataccagcgtttggatctatgcaaa
ctcaaccccacagacaccgatgctgtccgaggccaaatagtggtcagtttacagacacgg
gacagaataggcacaggaggttctgtagtagactgcagagggcttttggagaatgaagga
acggtttatgaagattctgggccggggaggccactgagctgcttcatggaggagccagcc
ccgtacacggacacgacgggagcggcgggaggaggcggctgccgcttcctggagtctccc
agccaggaccagagactgcaggcccagaggctccgcacccccgaggtcagagctcatgtc
cagacacctcagaacaggccccacggccaccagtcacctgagctacctgaaggctacgag
caaagaacaacggtacagggacaggtttattttttgcacacacagactggagtgagcacg
tggcacgacccaaggataccaagagaccttaacagtgtgaattgtgatgaactgggacct
ttgcctccaggctgggaagtcagaagtacagtttcaggaagaatatattttgtagatcat
aacaacagaaccacacaattcacagatccacgactacatcacatcatgaaccatcaatgc
cagctaaaagagcccagccagcagcctctaccagctccaaatgagggatcattggaagag
ggtgaggagttgcctgcacagagatatgaaagagacttggtacaaaagttgaaagttctt
agacatgagctgtctcttcagcaacctcaggctggtcactgtcgcattgaagtatccaga
gaggaaatatttgaggaatcctatcgtcagataatgaagatgaggccaaaggacttgaaa
aagaggcttatggtgaaattcagaggagaggaaggcctggattatggaggagtagcaaga
gagtggttgtatttactgtgccatgaaatgttgaatccctactatggactcttccagtac
tccacagataacatttacatgctgcaaatcaatccagactcttctatcaatcctgaccat
ttgtcttatttccattttgttggtcggataatgggtttggctgtgttccatggacactat
atcaacggggggttcacagttcccttttacaaacagctgctggggaagcccatccagctc
tccgatctggaatctgttgacccagaattacacaaaagtttagtctggatcttagagaac
gatatcacgccagtcctggaccatacattctgtgtggaacacaatgccttcgggaggatt
ttacagcatgaactcaaaccaaatggcaggaatattccagtgacagaagagaacaagaag
gaatatgtcaggctgtacgtgaactggaggttcatgagaggaatagaggcacagttcctg
gctctgcagaaaggttttaatgaacttattcctcaacatctccttaagccttttgaccag
aaggaacttgagctgatcataggaggcctggataagatagacctgaatgactggaagtcc
aacacccgcctaaagcactgcatggctgacagcaacattgtcaagtggttctggcaagca
gtggaaacgtttgatgaagaaagaagggcaaggctgctgcagtttgtgacgggctcgacg
cgtgtcccacttcaaggtttcaaggctttacaaggcgctgcaggacccagactgtttacc
atccatttaatagatgcaaacacagacaaccttccaaaagcccacacttgctttaaccgg
atcgacattccgccttatgagtcatacgagaagctttatgagaagctgttgacagctgtg
gaagagacatgtgggtttgctgtggaatga

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